基本信息
方晓东 男 博导 其他
电子邮件： fangxiaodong@gmail.com
通信地址： 深圳市盐田区洪安三街华大公寓7-1108
邮政编码：
电子邮件： fangxiaodong@gmail.com
通信地址： 深圳市盐田区洪安三街华大公寓7-1108
邮政编码：
研究领域
2006年加入华大基因，一直从事与基因组学大规模数据采集、分析和挖掘的科研活动和大规模基因组中心的运营和管理工作。了解生命科学领域的研究和产业发展方向，熟悉大规模基因组中心、生物信息学中心的筹建、运营和战略规划，有良好的团队组建和管理运营能力。研究方向主要是通过对基因组、表观组、转录组、蛋白质组、代谢组和微生物组等多个层面的组学数据进行分析和整合，探索生物的演化、发育、适应的分子机制，以及重大疾病发生发展的分子机理。熟悉新一代测序技术等高通量平台的技术特点和各种测序应用类型的数据特征、分析思路、方法策略，包括全新参考基因组构建、变异检测、群体遗传学、甲基化、组蛋白修饰等表观遗传修饰调控，编码及非编码RNA的转录调控，微生物组与宿主的互作等。
招生信息
招生专业
0710Z1-基因组学
086000-生物与医药
招生方向
肿瘤基因组与肠道菌群研究
群体基因组学研究
教育背景
2012-09--2015-10 哥本哈根大学 博士
2003-09--2006-07 华南热带农业大学 硕士
1999-09--2003-07 华南热带农业大学 学士
2003-09--2006-07 华南热带农业大学 硕士
1999-09--2003-07 华南热带农业大学 学士
工作经历
工作简历
2006-06~现在, 深圳华大基因科技服务有限公司, 副总裁、首席技术官
社会兼职
2017-03-22-今,研究员, 广州中医药大学 研究员
2015-07-01-2020-07-01,客座教授, 中南大学湘雅三医院客座教授
2013-08-31-2018-08-31,客座教授, 西安交大法医学院 客座教授
2015-07-01-2020-07-01,客座教授, 中南大学湘雅三医院客座教授
2013-08-31-2018-08-31,客座教授, 西安交大法医学院 客座教授
专利与奖励
专利成果
[1] 李英睿, 李瑞强, 方晓东, 李松岗, 余 昶, 王 俊, 杨焕明, 汪 建. 一种单核苷酸多态性检测方法. 中国: CN101539967, 2009-09-23.
出版信息
发表论文
[1] Yufen Huang, Puzi Jiang, Zhengjiao Liang, Rouxi Chen, Zhen Yue, Xuefeng Xie, Changge Guan, Xiaodong Fang. Assembly and analytical validation of a metagenomic reference catalog of human gut microbiota based on co-barcoding sequencing. FRONTIERS IN MICROBIOLOGY[J]. 2023, 第 8 作者 通讯作者 14: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10196144/.
[2] Weiming He, Jian Yang, Yi Jing, Lian Xu, Kang Yu, Xiaodong Fang, Tobias Marschall. NGenomeSyn: an easy-to-use and flexible tool for publication-ready visualization of syntenic relationships across multiple genomes. BIOINFORMATICS[J]. 2023, 第 6 作者 通讯作者 39(3): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027429/.
[3] Yin Zhang, Juan Shen, Wei Cheng, Bhaskar Roy, Ruizhen Zhao, Tailiang Chai, Yifei Sheng, Zhao Zhang, Xueting Chen, Weiming Liang, Weining Hu, Qijun Liao, Shanshan Pan, Wen Zhuang, Yangrui Zhang, Rouxi Chen, Junpu Mei, Hong Wei, Xiaodong Fang. Microbiota-mediated shaping of mouse spleen structure and immune function characterized by scRNA-seq and Stereo-seq. JOURNAL OF GENETICS AND GENOMICS[J]. 2023, 第 19 作者 通讯作者 http://dx.doi.org/10.1016/j.jgg.2023.04.012.
[4] Computational and Structural Biotechnology Journal. 2023, 通讯作者
[5] Computational and Structural Biotechnology Journal. 2023, 通讯作者
[6] Han, Lijuan, Zhao, Ling, Zhou, Yong, Yang, Chao, Xiong, Teng, Lu, Lin, Deng, Yusheng, Luo, Wen, Chen, Yang, Qiu, Qinwei, Shang, Xiaoxiao, Huang, Li, Mo, Zongchao, Huang, Shaogang, Huang, Suiping, Liu, Zhi, Yang, Wei, Zhai, Lixiang, Ning, Ziwan, Lin, Chengyuan, Huang, Tao, Cheng, Chungwah, Zhong, Linda L D, Li, Shuaicheng, Bian, Zhaoxiang, Fang, Xiaodong. Altered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity. ISME JOURNAL[J]. 2022, 第 26 作者 通讯作者 16(4): 983-996, http://dx.doi.org/10.1038/s41396-021-01123-5.
[7] Yang Wang, XiYin Li, WenJie Xu, Kun Wang, Bin Wu, Meng Xu, Yan Chen, LiJun Miao, ZhongWei Wang, Zhi Li, XiaoJuan Zhang, Zhan Yin, BoTong Zhou, YuLan Yang, ChengLong Zhu, MingLiang Hu, JiangMing Zheng, ChenGuang Feng, Qiang Qiu, LeTian Tian, Meng Lu, Fang Peng, WeiJia Lu, JinFeng Tong, JinGou Tong, BeiDe Fu, Peng Yu, Miao Ding, RuiHai Gan, QinQin Zhang, JianBo Jian, Chi Zhang, WeiMing He, Wei Yang, ZiCheng Zhao, QianQian Zhang, Qiang Gao, JunYang Xu, MingZhou Bai, YaPing Zhang, HuanMing Yang, XiaoDong Fang, Wen Wang, Li Zhou, JianFang Gui. Comparative genome anatomy reveals evolutionary insights into a unique amphitriploid fish. NATURE ECOLOGY & EVOLUTION[J]. 2022, 第 42 作者 通讯作者 6(9): 1354-1366, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439954/.
[8] Zeng, Bing, Huang, Peide, Du, Peina, Sun, Xiaohui, Huang, Xuanlin, Fang, Xiaodong, Li, Lin. Comprehensive Study of Germline Mutations and Double-Hit Events in Esophageal Squamous Cell Cancer. FRONTIERS IN ONCOLOGY[J]. 2021, 第 6 作者 通讯作者 11:
[9] Zhao, Ling, Yang, Wei, Chen, Yang, Huang, Fengjie, Lu, Lin, Lin, Chengyuan, Huang, Tao, Ning, Ziwan, Zhai, Lixiang, Zhong, Linda L D, Lam, Waiching, Yang, Zhen, Zhang, Xuan, Cheng, Chungwah, Han, Lijuan, Qiu, Qinwei, Shang, Xiaoxiao, Huang, Runyue, Xiao, Haitao, Ren, Zhenxing, Chen, Dongfeng, Sun, Silong, ElNezami, Hani, Cai, Zongwei, Lu, Aiping, Fang, Xiaodong, Jia, Wei, Bian, Zhaoxiang. A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome. JOURNAL OF CLINICAL INVESTIGATION[J]. 2020, 第 26 作者 通讯作者 130(1): 438-450, http://dx.doi.org/10.1172/JCI130976.
[10] Zhao, Jing, Tian, Xiao, Zhu, Yabing, Zhang, Zhihui, Rydkina, Elena, Yuan, Yongxian, Zhang, Hongyun, Roy, Bhaskar, Cornwell, Adam, Nevo, Eviatar, Shang, Xiaoxiao, Huang, Runyue, Kristiansen, Karsten, Seluanov, Andrei, Fang, Xiaodong, Gorbunova, Vera. Reply to: Transformation of naked mole-rat cells. NATURE. 2020, 第 11 作者583(7814): E8-+, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7917019/.
[11] Rui Xing, Yong Zhou, Jun Yu, Yingyan Yu, Yongzhan Nie, Wen Luo, Chao Yang, Teng Xiong, William K K Wu, Zhongwu Li, Yang Bing, Shuye Lin, Yaping Zhang, Yingqi Hu, Lin Li, Lijuan Han, Chen Yang, Shaogang Huang, Suiping Huang, Rui Zhou, Jing Li, Kaichun Wu, Daiming Fan, Guangbo Tang, Jianhua Dou, Zhenggang Zhu, Jiafu Ji, Xiaodong Fang, Youyong Lu. Whole-genome sequencing reveals novel tandem-duplication hotspots and a prognostic mutational signature in gastric cancer. NATURE COMMUNICATIONS[J]. 2019, 第 28 作者 通讯作者 10(1): 1-13, https://doaj.org/article/e5a9683dd37c418093b34ec48738cee1.
[12] Zhou, Xuming, Guang, Xuanmin, Sun, Di, Xu, Shixia, Li, Mingzhou, Seim, Inge, Jie, Wencai, Yang, Linfeng, Zhu, Qianhua, Xu, Jiabao, Gao, Qiang, Kaya, Alaattin, Dou, Qianhui, Chen, Bingyao, Ren, Wenhua, Li, Shuaicheng, Zhou, Kaiya, Gladyshev, Vadim N, Nielsen, Rasmus, Fang, Xiaodong, Yang, Guang. Population genomics of finless porpoises reveal an incipient cetacean species adapted to freshwater. NATURE COMMUNICATIONS[J]. 2018, 第 20 作者 通讯作者 9(1): https://doaj.org/article/e60a0d0e425842b684182d2f309fe086.
[13] Griesmann, Maximilian, Chang, Yue, Liu, Xin, Song, Yue, Haberer, Georg, Crook, Matthew B, BillaultPenneteau, Benjamin, Lauressergues, Dominique, Keller, Jean, Imanishi, Leandro, Roswanjaya, Yuda Purwana, Kohlen, Wouter, Pujic, Petar, Battenberg, Kai, Alloisio, Nicole, Liang, Yuhu, Hilhorst, Henk, Salgado, Marco G, Hocher, Valerie, Gherbi, Hassen, Svistoonoff, Sergio, Doyle, Jeff J, He, Shixu, Xu, Yan, Xu, Shanyun, Qu, Jing, Gao, Qiang, Fang, Xiaodong, Fu, Yuan, Normand, Philippe, Berry, Alison M, Wall, Luis G, Ane, JeanMichel, Pawlowski, Katharina, Xu, Xun, Yang, Huanming, Spannagl, Manuel, Mayer, Klaus F X, Wong, Gane KaShu, Parniske, Martin, Delaux, PierreMarc, Cheng, Shifeng. Phylogenomics reveals multiple losses of nitrogen-fixing root nodule symbiosis. SCIENCE[J]. 2018, 第 28 作者361(6398): 144-+, http://dx.doi.org/10.1126/science.aat1743.
[14] Zhou, Xuming, Sun, Di, Guang, Xuanmin, Ma, Siming, Fang, Xiaodong, Mariotti, Marco, Nielsen, Rasmus, Gladyshev, Vadim N, Yang, Guang. Molecular Footprints of Aquatic Adaptation Including Bone Mass Changes in Cetaceans. GENOME BIOLOGY AND EVOLUTION[J]. 2018, 第 5 作者10(3): 967-975, http://dx.doi.org/10.1093/gbe/evy062.
[15] Zhizhi Wang, Xiqian Ye, Min Shi, Fei Li, Zehua Wang, Yuenan Zhou, Qijuan Gu, Xiaotong Wu, Chuanlin Yin, Dianhao Guo, Rongmin Hu, Nana Hu, Ting Chen, Boying Zheng, Jiani Zou, Leqing Zhan, Shujun Wei, Yanping Wang, Jianhua Huang, Xiaodong Fang, Michael R Strand, Xuexin Chen. Parasitic insect-derived miRNAs modulate host development. NATURE COMMUNICATIONS[J]. 2018, 第 20 作者9(1): https://doaj.org/article/c330aba5f6fa472c93ed1748557e72a2.
[16] Guo, Runxin, Zhao, Yi, Zou, Quan, Fang, Xiaodong, Peng, Shaoliang. Bioinformatics applications on Apache Spark. GIGASCIENCE. 2018, 第 4 作者 通讯作者 7(8): http://dx.doi.org/10.1093/gigascience/giy098.
[17] Roy, Bhaskar, Zhao, Jing, Yang, Chao, Luo, Wen, Xiong, Teng, Li, Yong, Fang, Xiaodong, Gao, Guanjun, Singh, Chabungbam O, Madsen, Lise, Zhou, Yong, Kristiansen, Karsten. CRISPR/Cascade 9-Mediated Genome Editing-Challenges and Opportunities. FRONTIERS IN GENETICS[J]. 2018, 第 7 作者9: https://doaj.org/article/b06591309fb7473aab11fc40063feeb3.
[18] Wang, Wensheng, Mauleon, Ramil, Hu, Zhiqiang, Chebotarov, Dmytro, Tai, Shuaishuai, Wu, Zhichao, Li, Min, Zheng, Tianqing, Fuentes, Roven Rommel, Zhang, Fan, Mansueto, Locedie, Copetti, Dario, Sanciangco, Millicent, Palis, Kevin Christian, Xu, Jianlong, Sun, Chen, Fu, Binying, Zhang, Hongliang, Gao, Yongming, Zhao, Xiuqin, Shen, Fei, Cui, Xiao, Yu, Hong, Li, Zichao, Chen, Miaolin, Detras, Jeffrey, Zhou, Yongli, Zhang, Xinyuan, Zhao, Yue, Kudrna, Dave, Wang, Chunchao, Li, Rui, Jia, Ben, Lu, Jinyuan, He, Xianchang, Dong, Zhaotong, Xu, Jiabao, Li, Yanhong, Wang, Miao, Shi, Jianxin, Li, Jing, Zhang, Dabing, Lee, Seunghee, Hu, Wushu, Poliakov, Alexander, Dubchak, Inna, Ulat, Victor Jun, Borja, Frances Nikki, Mendoza, John Robert, Ali, Jauhar, Li, Jing, Gao, Qiang, Niu, Yongchao, Yue, Zhen, Naredo, Ma Elizabeth B, Talag, Jayson, Wang, Xueqiang, Li, Jinjie, Fang, Xiaodong, Yin, Ye, Glaszmann, JeanChristophe, Zhang, Jianwei, Li, Jiayang, Hamilton, Ruaraidh Sackville, Wing, Rod A, Ruan, Jue, Zhang, Gengyun, Wei, Chaochun, Alexandrov, Nickolai, McNally, Kenneth L, Li, Zhikang, Leung, Hei. Genomic variation in 3,010 diverse accessions of Asian cultivated rice. NATURE[J]. 2018, 第 59 作者557(7703): 43-+, http://dx.doi.org/10.1038/s41586-018-0063-9.
[19] Geng, Xiaofang, Li, Wanshun, Shang, Haitao, Gou, Qiang, Zhang, Fuchun, Zang, Xiayan, Zeng, Benhua, Li, Jiang, Wang, Ying, Ma, Ji, Guo, Jianlin, Jian, Jianbo, Chen, Bing, Qiao, Zhigang, Zhou, Minghui, Wei, Hong, Fang, Xiaodong, Xu, Cunshuan. A reference gene set construction using RNA-seq of multiple tissues of Chinese giant salamander, Andrias davidianus. GIGASCIENCE. 2017, 第 17 作者 通讯作者 6(3): 1-7, https://www.webofscience.com/wos/woscc/full-record/WOS:000403176800001.
[20] Fukushima, Kenji, Fang, Xiaodong, AlvarezPonce, David, Cai, Huimin, CarreteroPaulet, Lorenzo, Chen, Cui, Chang, TienHao, Farr, Kimberly M, Fujita, Tomomichi, Hiwatashi, Yuji, Hoshi, Yoshikazu, Imai, Takamasa, Kasahara, Masahiro, Librado, Pablo, Mao, Likai, Mori, Hitoshi, Nishiyama, Tomoaki, Nozawa, Masafumi, Palfalvi, Gergo, Pollard, Stephen T, Rozas, Julio, SanchezGracia, Alejandro, Sankoff, David, Shibata, Tomoko F, Shigenobu, Shuji, Sumikawa, Naomi, Uzawa, Taketoshi, Xie, Meiying, Zheng, Chunfang, Pollock, David D, Albert, Victor A, Li, Shuaicheng, Hasebe, Mitsuyasu. Genome of the pitcher plant Cephalotus reveals genetic changes associated with carnivory. NATURE ECOLOGY & EVOLUTION[J]. 2017, 第 2 作者1(3): https://www.webofscience.com/wos/woscc/full-record/WOS:000417170400013.
[21] 方晓东. enome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution. PNAS.. 2015, 第 1 作者 通讯作者
[22] Ai, Huashui, Fang, Xiaodong, Yang, Bin, Huang, Zhiyong, Chen, Hao, Mao, Likai, Zhang, Feng, Zhang, Lu, Cui, Leilei, He, Weiming, Yang, Jie, Yao, Xiaoming, Zhou, Lisheng, Han, Lijuan, Li, Jing, Sun, Silong, Xie, Xianhua, Lai, Boxian, Su, Ying, Lu, Yao, Yang, Hui, Huang, Tao, Deng, Wenjiang, Nielsen, Rasmus, Ren, Jun, Huang, Lusheng. Adaptation and possible ancient interspecies introgression in pigs identified by whole-genome sequencing. NATURE GENETICS[J]. 2015, 第 2 作者47(3): 217-+, http://dx.doi.org/10.1038/ng.3199.
[23] Fang, Xiaodong, Seim, Inge, Huang, Zhiyong, Gerashchenko, Maxim V, Xiong, Zhiqiang, Turanov, Anton A, Zhu, Yabing, Lobanov, Alexei V, Fan, Dingding, Yim, Sun Hee, Yao, Xiaoming, Ma, Siming, Yang, Lan, Lee, SangGoo, Kim, Eun Bae, Bronson, Roderick T, Sumbera, Radim, Buffenstein, Rochelle, Zhou, Xin, Krogh, Anders, Park, Thomas J, Zhang, Guojie, Wang, Jun, Gladyshev, Vadim N. Adaptations to a Subterranean Environment and Longevity Revealed by the Analysis of Mole Rat Genomes. CELL REPORTS[J]. 2014, 第 1 作者8(5): 1354-1364, https://doaj.org/article/365fa891334547f7956c0ac9ecf3f840.
[24] Fang, Xiaodong, Nevo, Eviatar, Han, Lijuan, Levanon, Erez Y, Zhao, Jing, Avivi, Aaron, Larkin, Denis, Jiang, Xuanting, Feranchuk, Sergey, Zhu, Yabing, Fishman, Alla, Feng, Yue, Sher, Noa, Xiong, Zhiqiang, Hankeln, Thomas, Huang, Zhiyong, Gorbunova, Vera, Zhang, Lu, Zhao, Wei, Wildman, Derek E, Xiong, Yingqi, Gudkov, Andrei, Zheng, Qiumei, Rechavi, Gideon, Liu, Sanyang, Bazak, Lily, Chen, Jie, Knisbacher, Binyamin A, Lu, Yao, Shams, Imad, Gajda, Krzysztof, Farre, Marta, Kim, Jaebum, Lewin, Harris A, Ma, Jian, Band, Mark, Bicker, Anne, Kranz, Angela, Mattheus, Tobias, Schmidt, Hanno, Seluanov, Andrei, Azpurua, Jorge, McGowen, Michael R, Ben Jacob, Eshel, Li, Kexin, Peng, Shaoliang, Zhu, Xiaoqian, Liao, Xiangke, Li, Shuaicheng, Krogh, Anders, Zhou, Xin, Brodsky, Leonid, Wang, Jun. Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax. NATURE COMMUNICATIONS[J]. 2014, 第 1 作者5: https://www.webofscience.com/wos/woscc/full-record/WOS:000338830400002.
[25] Seim, Inge, Fang, Xiaodong, Xiong, Zhiqiang, Lobanov, Alexey V, Huang, Zhiyong, Ma, Siming, Feng, Yue, Turanov, Anton A, Zhu, Yabing, Lenz, Tobias L, Gerashchenko, Maxim V, Fan, Dingding, Yim, Sun Hee, Yao, Xiaoming, Jordan, Daniel, Xiong, Yingqi, Ma, Yong, Lyapunov, Andrey N, Chen, Guanxing, Kulakova, Oksana I, Sun, Yudong, Lee, SangGoo, Bronson, Roderick T, Moskalev, Alexey A, Sunyaev, Shamil R, Zhang, Guojie, Krogh, Anders, Wang, Jun, Gladyshev, Vadim N. Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii. NATURE COMMUNICATIONS[J]. 2013, 第 2 作者4: https://www.webofscience.com/wos/woscc/full-record/WOS:000323749900001.
[26] Zhang, Guofan, Fang, Xiaodong, Guo, Ximing, Li, Li, Luo, Ruibang, Xu, Fei, Yang, Pengcheng, Zhang, Linlin, Wang, Xiaotong, Qi, Haigang, Xiong, Zhiqiang, Que, Huayong, Xie, Yinlong, Holland, Peter W H, Paps, Jordi, Zhu, Yabing, Wu, Fucun, Chen, Yuanxin, Wang, Jiafeng, Peng, Chunfang, Meng, Jie, Yang, Lan, Liu, Jun, Wen, Bo, Zhang, Na, Huang, Zhiyong, Zhu, Qihui, Feng, Yue, Mount, Andrew, Hedgecock, Dennis, Xu, Zhe, Liu, Yunjie, DomazetLoso, Tomislav, Du, Yishuai, Sun, Xiaoqing, Zhang, Shoudu, Liu, Binghang, Cheng, Peizhou, Jiang, Xuanting, Li, Juan, Fan, Dingding, Wang, Wei, Fu, Wenjing, Wang, Tong, Wang, Bo, Zhang, Jibiao, Peng, Zhiyu, Li, Yingxiang, Li, Na, Wang, Jinpeng, Chen, Maoshan, He, Yan, Tan, Fengji, Song, Xiaorui, Zheng, Qiumei, Huang, Ronglian, Yang, Hailong, Du, Xuedi, Chen, Li, Yang, Mei, Gaffney, Patrick M, Wang, Shan, Luo, Longhai, She, Zhicai, Ming, Yao, Huang, Wen, Zhang, Shu, Huang, Baoyu, Zhang, Yong, Qu, Tao, Ni, Peixiang, Miao, Guoying, Wang, Junyi, Wang, Qiang, Steinberg, Christian E W, Wang, Haiyan, Li, Ning, Qian, Lumin, Zhang, Guojie, Li, Yingrui, Yang, Huanming, Liu, Xiao, Wang, Jian, Yin, Ye, Wang, Jun. The oyster genome reveals stress adaptation and complexity of shell formation. NATURE[J]. 2012, 第 2 作者490(7418): 49-54, https://www.webofscience.com/wos/woscc/full-record/WOS:000309446800030.
[27] Fang, Xiaodong, Mu, Yulian, Huang, Zhiyong, Li, Yong, Han, Lijuan, Zhang, Yanfeng, Feng, Yue, Chen, Yuanxin, Jiang, Xuanting, Zhao, Wei, Sun, Xiaoqing, Xiong, Zhiqiang, Yang, Lan, Liu, Huan, Fan, Dingding, Mao, Likai, Ren, Lijie, Liu, Chuxin, Wang, Juan, Li, Kui, Wang, Guangbiao, Yang, Shulin, Lai, Liangxue, Zhang, Guojie, Li, Yingrui, Wang, Jun, Bolund, Lars, Yang, Huanming, Wang, Jian, Feng, Shutang, Li, Songgang, Du, Yutao. The sequence and analysis of a Chinese pig genome. GIGASCIENCE[J]. 2012, 第 1 作者1(1): 16-16, https://doaj.org/article/1de8892f7950426289030339e59802d0.
[28] Yan, Guangmei, Zhang, Guojie, Fang, Xiaodong, Zhang, Yanfeng, Li, Cai, Ling, Fei, Cooper, David N, Li, Qiye, Li, Yan, van Gool, Alain J, Du, Hongli, Chen, Jiesi, Chen, Ronghua, Zhang, Pei, Huang, Zhiyong, Thompson, John R, Meng, Yuhuan, Bai, Yinqi, Wang, Jufang, Zhuo, Min, Wang, Tao, Huang, Ying, Wei, Liqiong, Li, Jianwen, Wang, Zhiwen, Hu, Haofu, Yang, Pengcheng, Le, Liang, Stenson, Peter D, Li, Bo, Liu, Xiaoming, Ball, Edward V, An, Na, Huang, Quanfei, Zhang, Yong, Fan, Wei, Zhang, Xiuqing, Li, Yingrui, Wang, Wen, Katze, Michael G, Su, Bing, Nielsen, Rasmus, Yang, Huanming, Wang, Jun, Wang, Xiaoning, Wang, Jian. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. NATURE BIOTECHNOLOGY[J]. 2011, 第 3 作者29(11): 1019-U89, https://www.webofscience.com/wos/woscc/full-record/WOS:000296801300023.
[29] Fang, Xiaodong, Zhang, Yanfeng, Zhang, Rui, Yang, Lixin, Li, Ming, Ye, Kaixiong, Guo, Xiaosen, Wang, Jun, Su, Bing. Genome sequence and global sequence variation map with 5.5 million SNPs in Chinese rhesus macaque. GENOME BIOLOGY[J]. 2011, 第 1 作者12(7): R63-R63, http://159.226.149.42:8080/handle/353002/6836.
[30] Kim, Eun Bae, Fang, Xiaodong, Fushan, Alexey A, Huang, Zhiyong, Lobanov, Alexei V, Han, Lijuan, Marino, Stefano M, Sun, Xiaoqing, Turanov, Anton A, Yang, Pengcheng, Yim, Sun Hee, Zhao, Xiang, Kasaikina, Marina V, Stoletzki, Nina, Peng, Chunfang, Polak, Paz, Xiong, Zhiqiang, Kiezun, Adam, Zhu, Yabing, Chen, Yuanxin, Kryukov, Gregory V, Zhang, Qiang, Peshkin, Leonid, Yang, Lan, Bronson, Roderick T, Buffenstein, Rochelle, Wang, Bo, Han, Changlei, Li, Qiye, Chen, Li, Zhao, Wei, Sunyaev, Shamil R, Park, Thomas J, Zhang, Guojie, Wang, Jun, Gladyshev, Vadim N. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. NATURE[J]. 2011, 第 2 作者479(7372): 223-227, https://www.webofscience.com/wos/woscc/full-record/WOS:000298030800041.
[2] Weiming He, Jian Yang, Yi Jing, Lian Xu, Kang Yu, Xiaodong Fang, Tobias Marschall. NGenomeSyn: an easy-to-use and flexible tool for publication-ready visualization of syntenic relationships across multiple genomes. BIOINFORMATICS[J]. 2023, 第 6 作者 通讯作者 39(3): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10027429/.
[3] Yin Zhang, Juan Shen, Wei Cheng, Bhaskar Roy, Ruizhen Zhao, Tailiang Chai, Yifei Sheng, Zhao Zhang, Xueting Chen, Weiming Liang, Weining Hu, Qijun Liao, Shanshan Pan, Wen Zhuang, Yangrui Zhang, Rouxi Chen, Junpu Mei, Hong Wei, Xiaodong Fang. Microbiota-mediated shaping of mouse spleen structure and immune function characterized by scRNA-seq and Stereo-seq. JOURNAL OF GENETICS AND GENOMICS[J]. 2023, 第 19 作者 通讯作者 http://dx.doi.org/10.1016/j.jgg.2023.04.012.
[4] Computational and Structural Biotechnology Journal. 2023, 通讯作者
[5] Computational and Structural Biotechnology Journal. 2023, 通讯作者
[6] Han, Lijuan, Zhao, Ling, Zhou, Yong, Yang, Chao, Xiong, Teng, Lu, Lin, Deng, Yusheng, Luo, Wen, Chen, Yang, Qiu, Qinwei, Shang, Xiaoxiao, Huang, Li, Mo, Zongchao, Huang, Shaogang, Huang, Suiping, Liu, Zhi, Yang, Wei, Zhai, Lixiang, Ning, Ziwan, Lin, Chengyuan, Huang, Tao, Cheng, Chungwah, Zhong, Linda L D, Li, Shuaicheng, Bian, Zhaoxiang, Fang, Xiaodong. Altered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity. ISME JOURNAL[J]. 2022, 第 26 作者 通讯作者 16(4): 983-996, http://dx.doi.org/10.1038/s41396-021-01123-5.
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科研活动
科研项目
（ 1 ） 基于转录组学的裸鼹鼠和盲鼹鼠天然抗癌的分子机制, 主持, 国家级, 2017-01--2020-12
（ 2 ） 血脂紊乱影响精子发生的生物标志物的鉴定和临床干预, 参与, 国家级, 2013-01--2017-08
（ 3 ） 基因大数据分析及产业化研究, 参与, 省级, 2016-01--2018-04
（ 4 ） 基于高效图处理的基因拼接分析研究, 参与, 省级, 2017-01--2019-12
（ 5 ） 结直肠癌筛查和疗效预后评估的芯片开发及临床应用规范的建立, 参与, 省级, 2016-01--2018-09
（ 2 ） 血脂紊乱影响精子发生的生物标志物的鉴定和临床干预, 参与, 国家级, 2013-01--2017-08
（ 3 ） 基因大数据分析及产业化研究, 参与, 省级, 2016-01--2018-04
（ 4 ） 基于高效图处理的基因拼接分析研究, 参与, 省级, 2017-01--2019-12
（ 5 ） 结直肠癌筛查和疗效预后评估的芯片开发及临床应用规范的建立, 参与, 省级, 2016-01--2018-09