基本信息

董宇辉 男 博导 高能物理研究所
电子邮件:dongyh@ihep.ac.cn
通信地址:北京市石景山区玉泉路19号(乙)中国科学院高能物理研究所
邮政编码:100049
研究领域
(1)蛋白质结构解析方法研究;
(2)时间分辨蛋白结构研究;
(3)X射线生物成像。
招生信息
招生专业
070205-凝聚态物理
071010-生物化学与分子生物学
071011-生物物理学
071010-生物化学与分子生物学
071011-生物物理学
招生方向
蛋白质结构和功能,X射线晶体学
DNA损伤修复的结构生物学研究
溶液状态蛋白质结构研究
DNA损伤修复的结构生物学研究
溶液状态蛋白质结构研究
教育背景
1990-09--1995-07 中国科学院高能物理研究所 理学博士
1986-09--1990-07 中山大学物理系 理学学士
1986-09--1990-07 中山大学物理系 理学学士
学历
-- 研究生
学位
-- 博士
工作经历
1995.7-1997.7:中国科学院物理研究所博士后;
1997.7-2001.1:意大利Trento大学工学院,博士后,客座研究员;
2001.1至今:入选中国科学院“引进国外杰出人才”,任中国科学院高能物理研究所研究员。
工作简历
2001-01~现在, 中国科学院高能物理研究所, 研究员
1997-07~2001-01,意大利Trento大学工学院, 博士后,客座研究员
1995-07~1997-07,中国科学院物理研究所, 博士后
1997-07~2001-01,意大利Trento大学工学院, 博士后,客座研究员
1995-07~1997-07,中国科学院物理研究所, 博士后
教授课程
X射线晶体学(近代物理方向)
科研实践Ⅱ-前沿物理研究******
同步辐射应用概论
科研实践Ⅰ-综合物理实验******
X射线晶体学
结构生物学导论
X射线晶体学(2)
X射线晶体学(1)
X射线晶体学(2)
X射线晶体学(1)
科研实践Ⅱ-前沿物理研究******
同步辐射应用概论
科研实践Ⅰ-综合物理实验******
X射线晶体学
结构生物学导论
X射线晶体学(2)
X射线晶体学(1)
X射线晶体学(2)
X射线晶体学(1)
专利与奖励
北京市科技进步二等奖
专利成果
[1] 李明, 张冬霓, 刘鹏, 张常睿, 崔荣丽, 盛伟繁, 董宇辉, 陶冶. 一种分频拼接干涉仪. CN: CN116718103A, 2023-09-08.
[2] 李明, 张冬霓, 李啸宇, 陆辉华, 黎刚, 董宇辉, 盛伟繁, 刘鹏. 芒果扭摆器. CN: CN114501769A, 2022-05-13.
[3] 李明, 张冬霓, 李啸宇, 陆辉华, 黎刚, 董宇辉, 盛伟繁, 刘鹏. 芒果扭摆器. CN: CN114501769A, 2022-05-13.
[4] 李明, 张冬霓, 李啸宇, 陆辉华, 黎刚, 董宇辉, 盛伟繁, 刘鹏. 芒果扭摆器. CN: CN114501769A, 2022-05-13.
[5] 王文佳, 常广才, 胡凌飞, 张连辉, 董宇辉, 刘鹏. 去除X射线散射和衍射实验中模糊效应的方法. CN: CN104268421B, 2017-07-28.
[6] 王文佳, 常广才, 胡凌飞, 张连辉, 董宇辉, 刘鹏. 去除X射线散射和衍射实验中模糊效应的方法. CN: CN104268421A, 2015-01-07.
[2] 李明, 张冬霓, 李啸宇, 陆辉华, 黎刚, 董宇辉, 盛伟繁, 刘鹏. 芒果扭摆器. CN: CN114501769A, 2022-05-13.
[3] 李明, 张冬霓, 李啸宇, 陆辉华, 黎刚, 董宇辉, 盛伟繁, 刘鹏. 芒果扭摆器. CN: CN114501769A, 2022-05-13.
[4] 李明, 张冬霓, 李啸宇, 陆辉华, 黎刚, 董宇辉, 盛伟繁, 刘鹏. 芒果扭摆器. CN: CN114501769A, 2022-05-13.
[5] 王文佳, 常广才, 胡凌飞, 张连辉, 董宇辉, 刘鹏. 去除X射线散射和衍射实验中模糊效应的方法. CN: CN104268421B, 2017-07-28.
[6] 王文佳, 常广才, 胡凌飞, 张连辉, 董宇辉, 刘鹏. 去除X射线散射和衍射实验中模糊效应的方法. CN: CN104268421A, 2015-01-07.
出版信息
发表论文
[1] Xiaoyi Zhao, Zheng Dong, Chenglong Zhang, Himadri Shikhar Gupta, Zhonghua Wu, Wenqiang Hua, Junrong zhang, Pengyu huang, Yuhui Dong, Yi Zhang. A step towards 6D WAXD tensor tomography. IUCrJ[J]. 2024, 第 9 作者 通讯作者 11(4): 502-509, https://journals.iucr.org/m/issues/2024/04/00/fs5219/index.html.
[2] Zhongzheng Zhou, Chun Li, Longlong Fan, Zheng Dong, Wenhui Wang, Chen Liu, Bingbing Zhang, Xiaoyan Liu, Kai Zhang, Ling Wang, Yi Zhang, Yuhui Dong. Denoising an X-ray image by exploring the power of its physical symmetry. Journal of Applied Crystallography[J]. 2024, 第 12 作者57(3): 741-754, https://journals.iucr.org/paper?S1600576724002899.
[3] Minghui Sun, Zheng Dong, Liyuan Wu, Haodong Yao, Wenchao Niu, Deting Xu, Ping Chen, Himadri Shikhar Gupta, Yi Zhang, Yuhui Dong, Chunying Chen, Lina Zhao. Fast extraction of three-dimensional nanofiber orientation from WAXD patterns using machine learning. IUCrJ[J]. 2023, 第 10 作者10(3): https://journals.iucr.org/m/issues/2023/03/00/ro5032/.
[4] Zhongzheng Zhou, Chun Li, Xiaoxue Bi, Chenglong Zhang, Yingke Huang, Jian Zhuang, Wenqiang Hua, Zheng Dong, Lina Zhao, Yi Zhang, Yuhui Dong. A machine learning model for textured X-ray scattering and diffraction image denoising. npj Computational Materials[J]. 2023, 第 11 作者 通讯作者 https://www.nature.com/articles/s41524-023-01011-w.
[5] Zhen Zhang, Xiaoxue Bi, Pengcheng Li, Chenglong Zhang, Yiming Yang, Yu Liu, Gang Chen, Yuhui Dong, Gongfa Liu, Yi Zhang. Automatic synchrotron tomographic alignment schemes based on genetic algorithms and human-in-the-loop software. Journal of Synchrotron Radiation[J]. 2023, 第 8 作者30(1): 169-178, https://journals.iucr.org/s/issues/2023/01/00/tv5039/index.html.
[6] 潘新宇, 毕筱雪, 董政, 耿直, 徐晗, 张一, 董宇辉, 张承龙. 叠层相干衍射成像算法发展综述. 物理学报[J]. 2023, 第 7 作者72(5): 102-122, https://wulixb.iphy.ac.cn/en/article/doi/10.7498/aps.72.20221889.
[7] Xinyu Pan, Shuo Wang, Zhongzheng Zhou, Liang Zhou, Peng Liu, Chun Li, Wenhui Wang, Chenglong Zhang, Yuhui Dong, Yi Zhang. An efficient ptychography reconstruction strategy through fine-tuning of large pre-trained deep learning model. ISCIENCE[J]. 2023, 第 9 作者26(12): 108420, http://dx.doi.org/10.1016/j.isci.2023.108420.
[8] Dong, Zheng, Chen, Chen, Wen, Kaihua, Zhao, Xiaoyi, Guo, Xihong, Zhou, Zhongzheng, Chang, Guangcai, Zhang, Yi, Dong, Yuhui. A Freestanding Chitin-Derived Hierarchical Nanocomposite for Developing Electrodes in Future Supercapacitor Industry. POLYMERS[J]. 2022, 第 9 作者 通讯作者 14(1): http://dx.doi.org/10.3390/polym14010195.
[9] Dong, Zheng, Chen, Sen, Gupta, Himadri S, Zhao, Xiaoyi, Yang, Yiming, Chang, Guangcai, Xue, Jian, Zhang, Yiyang, Luo, Shengnian, Dong, Yuhui, Zhang, Yi. In situ determination of the extreme damage resistance behavior in stomatopod dactyl club. JOURNAL OF SYNCHROTRON RADIATION[J]. 2022, 第 10 作者 通讯作者 29(Pt 3): 775-786, https://www.doi.org/10.1107/S1600577522001217.
[10] Liu, Yu, Geng, YanDa, Bi, XiaoXue, Li, Xiang, Tao, Ye, Cao, JianShe, Dong, YuHui, Zhang, Yi. Mamba: a systematic software solution for beamline experiments at HEPS. JOURNAL OF SYNCHROTRON RADIATION[J]. 2022, 第 7 作者29(Pt 3): 664-669, http://dx.doi.org/10.1107/S1600577522002697.
[11] Du, Xuejian, Gao, ZengQiang, Geng, Zhi, Dong, YuHui, Zhang, Heng. Structure and Biochemical Characteristics of the Methyltransferase Domain of RNA Capping Enzyme from African Swine Fever Virus. JOURNAL OF VIROLOGY[J]. 2021, 第 4 作者 通讯作者 95(5): https://www.webofscience.com/wos/woscc/full-record/WOS:000619748400004.
[12] Zhu, Zhongzhu, Xu, Han, Hu, Lingfei, Li, Ming, Liu, Peng, Dong, Yuhui, Zhou, Liang. A wave optics model for the effect of partial coherence on coherent diffractive imaging. JOURNAL OF SYNCHROTRON RADIATION[J]. 2021, 第 6 作者28: 499-504, https://www.webofscience.com/wos/woscc/full-record/WOS:000626355600016.
[13] Wang, Shuangyue, Geng, Zhi, Zhang, Heng, She, Zhun, Dong, Yuhui. The Pseudomonas aeruginosa PAAR2 cluster encodes a putative VRR-NUC domain-containing effector. FEBS JOURNAL[J]. 2021, 第 5 作者 通讯作者 288(19): 5755-5767, http://dx.doi.org/10.1111/febs.15870.
[14] Wen, Haiying, Liu, Guangfeng, Geng, Zhi, Zhang, Heng, Li, Yanhua, She, Zhun, Dong, Yuhui. Structure and SAXS studies unveiled a novel inhibition mechanism of the Pseudomonas aeruginosa T6SS TseT-TsiT complex. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2021, 第 7 作者 通讯作者 188: 450-459, http://dx.doi.org/10.1016/j.ijbiomac.2021.08.029.
[15] Zhang, Likui, Yan, Yuhua, Gan, Qi, She, Zhun, Zhu, Keli, Wang, Jinhui, Gao, Zengqiang, Dong, Yuhui, Gong, Yong. Structural and functional characterization of the deep-sea thermophilic bacteriophage GVE2 tailspike protein. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 第 8 作者164: 4415-4422, http://dx.doi.org/10.1016/j.ijbiomac.2020.09.053.
[16] Wen, Haiying, Geng, Zhi, Gao, Zengqiang, She, Zhun, Dong, Yuhui. Characterization of the Pseudomonas aeruginosa T6SS PldB immunity proteins PA5086, PA5087 and PA5088 explains a novel stockpiling mechanism. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS[J]. 2020, 第 5 作者 通讯作者 76(Pt 5): 222-227, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000530263400005.
[17] Zhang, Yi, Garrevoet, Jan, Wang, Yanhong, Roeh, Jan Torben, Terrill, Nicholas J, Falkenberg, Gerald, Dong, Yuhui, Gupta, Himadri S. Molecular to Macroscale Energy Absorption Mechanisms in Biological Body Armour Illuminated by Scanning X-ray Diffraction with In Situ Compression. ACS NANO[J]. 2020, 第 7 作者 通讯作者 14(12): 16535-16546, http://dx.doi.org/10.1021/acsnano.0c02879.
[18] Liu, Ying, Gao, Zengqiang, Liu, Guangfeng, Geng, Zhi, Dong, Yuhui, Zhang, Heng. Structural Insights Into the Transcriptional Regulation of HigBA Toxin-Antitoxin System by Antitoxin HigA in Pseudomonas aeruginosa. FRONTIERS IN MICROBIOLOGY[J]. 2020, 第 5 作者 通讯作者 10: https://doaj.org/article/1cb346be006d4094ad552f2f2af27347.
[19] Zhou, Juan, Gao, Zengqiang, Zhang, Heng, Dong, Yuhui. Crystal structure of the nucleoid-associated protein Fis (PA4853) from Pseudomonas aeruginosa. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS[J]. 2020, 第 4 作者 通讯作者 76(Pt 5): 209-215, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000530263400003.
[20] Hu, Menglu, Gao, Zengqiang, Zhou, Qiang, Geng, Zhi, Dong, Yuhui. A noise and artifact suppression using resampling(NASR)method to facilitate de novo protein structure determination. 辐射探测技术与方法(英文)[J]. 2019, 第 5 作者 通讯作者 3(3): 247-255, http://lib.cqvip.com/Qikan/Article/Detail?id=7106714880.
[21] Xu, Xuefang, Zhang, Heng, Huang, Ying, Zhang, Yuan, Wu, Changde, Gao, Pengya, Teng, Zhongqiu, Luo, Xuelian, Peng, Xiaojing, Wang, Xiaoyuan, Wang, Dai, Pu, Ji, Zhao, Hongqing, Lu, Xuancheng, Lu, Shuangshuang, Ye, Changyun, Dong, Yuhui, Lan, Ruiting, Xu, Jianguo. Beyond a Ribosomal RNA Methyltransferase, the Wider Role of MraW in DNA Methylation, Motility and Colonization in Escherichia coli O157:H7. FRONTIERS IN MICROBIOLOGY[J]. 2019, 第 17 作者10: https://doaj.org/article/faf56df12b91467192cfbd60fce4ad94.
[22] Zhun She, Zhi Geng, JianHua Xu, YanHua Li, YuHui Dong. Structural characterization of the Imm52 family protein TsiT in Pseudomonas aeruginosa. PROTEIN SCIENCE : A PUBLICATION OF THE PROTEIN SOCIETY[J]. 2019, 第 5 作者 通讯作者 28(5): 971-975,
[23] Shi, Lingling, Gao, Zengqiang, Zhang, Tianyi, Zhang, Heng, Dong, Yuhui. Crystal structure of the type VI immunity protein Tdi1 (Atu4351) from Agrobacterium tumefaciens. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS[J]. 2019, 第 5 作者 通讯作者 75(Pt 3): 153-158, http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000460520900003.
[24] Xu, BingShuang, Liu, Min, Zhou, Ke, Geng, Zhi, Gao, ZengQiang, Dong, YuHui, She, Zhun, Liu, QuanSheng. Conformational changes of antitoxin HigA from Escherichia coli str. K-12 upon binding of its cognate toxin HigB reveal a new regulation mechanism in toxin-antitoxin systems. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2019, 第 6 作者514(1): 37-43, http://dx.doi.org/10.1016/j.bbrc.2019.04.061.
[25] She, Zhun, Geng, Zhi, Xu, JianHua, Li, YanHua, Dong, YuHui. Structural characterization of the Imm52 family protein TsiT in Pseudomonas aeruginosa. PROTEIN SCIENCE[J]. 2019, 第 5 作者 通讯作者 28(5): 971-975,
[26] Kun Tang, Lei Zheng, Yi Dong Zhao, Shu Hu Liu, Chen Yan Ma, Yu Hui Dong. A micro‐focusing and high‐flux‐throughput beamline design using a bending magnet for microscopic XAFS at the High Energy Photon Source. Journal of Synchrotron Radiation[J]. 2019, 第 6 作者26: 1835-1842, https://www.doi.org/10.1107/S160057751900715X.
[27] Zhang, Zhenfeng, Zhao, Mohan, Chen, Yuanyuan, Wang, Li, Liu, Qinghua, Dong, Yuhui, Gong, Yong, Huang, Li. Architectural roles of Cren7 in folding crenarchaeal chromatin filament. MOLECULAR MICROBIOLOGY[J]. 2019, 第 6 作者111(3): 556-569, https://www.webofscience.com/wos/woscc/full-record/WOS:000461081000002.
[28] Geng, Zhi, Hu, Menglu, She, Zhun, Zhou, Qiang, Gao, Zengqiang, Dong, Yuhui. An iterative refinement method combining detector geometry optimization and diffraction model refinement in serial femtosecond crystallography. 辐射探测技术与方法(英文)[J]. 2018, 第 6 作者 通讯作者 2(1): 190-199, http://lib.cqvip.com/Qikan/Article/Detail?id=7106714838.
[29] Wang, Hanqian, Liu, Xiaoqing, Zhao, Jintong, Yue, Qingxia, Yan, Yuhua, Gao, Zengqiang, Dong, Yuhui, Zhang, Zhiyong, Fan, Yunliu, Tian, Jian, Wu, Ningfeng, Gong, Yong. Crystal structures of multicopper oxidase CueO G304K mutant: structural basis of the increased laccase activity. SCIENTIFIC REPORTS[J]. 2018, 第 7 作者8(1): https://doaj.org/article/6ba9bea98d66419ea5c86adba6f084ec.
[30] Li, Huanhuan, Yang, Kai, Wang, Wenjia, Niu, Yingbo, Li, Jun, Dong, Yuhui, Liu, Yingfang, Wang, Chihchen, Wang, Lei, Liang, Huanhuan. Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2018, 第 6 作者293(4): 1192-1202, http://dx.doi.org/10.1074/jbc.M117.797290.
[31] Jia, Xuanyan, Yao, Jianyun, Gao, Zengqiang, Liu, Guangfeng, Dong, YuHui, Wang, Xiaoxue, Zhang, Heng. Structure-function analyses reveal the molecular architecture and neutralization mechanism of a bacterial HEPN-MNT toxin-antitoxin system. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2018, 第 5 作者293(18): 6812-6823, http://dx.doi.org/10.1074/jbc.RA118.002421.
[32] Zhang, Tianyi, Geng, Zhi, Zhang, Heng, Zhou, Liang, Dong, Yuhui. Electron densitymap evaluation functions for determining the quality of protein crystal structures. 辐射探测技术与方法(英文)[J]. 2018, 第 5 作者 通讯作者 2(2): 42, http://lib.cqvip.com/Qikan/Article/Detail?id=7106713489.
[33] Yuan, Fei, Gao, ZengQiang, Majerciak, Vladimir, Bai, Lei, Hu, MengLu, Lin, XiaoXi, Zheng, ZhiMing, Dong, YuHui, Lan, Ke. The crystal structure of KSHV ORF57 reveals dimeric active sites important for protein stability and function. PLOS PATHOGENS[J]. 2018, 第 8 作者 通讯作者 14(8): http://dx.doi.org/10.1371/journal.ppat.1007232.
[34] Dong, Jianshu, Li, Fahui, Gao, Feng, Wei, Jia, Lin, Yajing, Zhang, Yong, Lou, Jizhong, Liu, Guangfeng, Dong, Yuhui, Liu, Lin, Liu, Hongmin, Wang, Jiangyun, Gong, Weimin. Structure of tRNA-Modifying Enzyme TiaS and Motions of Its Substrate Binding Zinc Ribbon. JOURNAL OF MOLECULAR BIOLOGY[J]. 2018, 第 9 作者430(21): 4183-4194, http://dx.doi.org/10.1016/j.jmb.2018.08.015.
[35] Yang, Jingsi, Wang, Fei, Yang, Dan, Zhou, Ke, Liu, Min, Gao, Zengqiang, Liu, Peng, Dong, Yuhui, Zhang, Jianjun, Liu, Quansheng. Structural and biochemical characterization of the yeast HD domain containing protein YGK1 reveals a metal-dependent nucleoside 5′-monophosphatase. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2018, 第 8 作者 通讯作者 501(3): 674-681, http://dx.doi.org/10.1016/j.bbrc.2018.05.047.
[36] Zhang, Zhenfeng, Zhao, Mohan, Wang, Li, Chen, Yuanyuan, Dong, Yuhui, Gong, Yong, Huang, Li. Roles of Leu28 side chain intercalation in the interaction between Cren7 and DNA. BIOCHEMICAL JOURNAL[J]. 2017, 第 5 作者474(10): 1727-1739, http://www.corc.org.cn/handle/1471x/2177413.
[37] Yang, Jingsi, Xu, Bingshuang, Gao, Zengqiang, Zhou, Ke, Liu, Peng, Dong, Yuhui, Zhang, Jianjun, Liu, Quansheng. HicAB toxin-antitoxin complex from Escherichia coli: expression and crystallization. ACTACRYSTALLOGRAPHICASECTIONFSTRUCTURALBIOLOGYCOMMUNICATIONS[J]. 2017, 第 6 作者73(Pt 9): 505-510, https://www.webofscience.com/wos/woscc/full-record/WOS:000409298600002.
[38] Yang, Xiaoyun, Li, Yanhua, Gao, Zengqiang, Li, Zongqiang, Xu, Jianhua, Wang, Wenjia, Dong, Yuhui. Structural analysis of Wss1 protein from saccharomyces cerevisiae. SCIENTIFIC REPORTS[J]. 2017, 第 7 作者 通讯作者 7(1): https://doaj.org/article/7fb2675efc6748e98d4e1ef53b356b3a.
[39] Lin, QingPeng, Gao, ZengQiang, Geng, Zhi, Zhang, Heng, Dong, YuHui. Crystal structure of the putative cytoplasmic protein STM0279 (Hcp2) from Salmonella typhimurium. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS[J]. 2017, 第 5 作者 通讯作者 73(Pt 8): 463-468, http://www.corc.org.cn/handle/1471x/2176933.
[40] Yang, Jingsi, Xu, Bingshuang, Gao, Zengqiang, Zhou, Ke, Liu, Peng, Dong, Yuhui, Zhang, Jianjun, Liu, Quansheng. HicAB toxin-antitoxin complex from Escherichia coli: expression and crystallization. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS[J]. 2017, 第 6 作者73(9): 505-510, https://www.webofscience.com/wos/woscc/full-record/WOS:000409298600002.
[41] Yang, XiaoYun, Li, ZongQiang, Gao, ZengQiang, Wang, WenJia, Geng, Zhi, Xu, JianHua, She, Zhun, Dong, YuHui. Structural and SAXS analysis of Tle5-Tli5 complex reveals a novel inhibition mechanism of H2-T6SS in Pseudomonas aeruginosa. PROTEIN SCIENCE[J]. 2017, 第 8 作者 通讯作者 26(10): 2083-2091, http://www.corc.org.cn/handle/1471x/2177080.
[42] Wang, Wenjia, Yang, Xiaoyun, Chang, Guangcai, An, Pengfei, Cha, Kewen, Dong, Yuhui, Liu, Peng. A method to stabilize the incident X-ray energy for anomalous diffraction measurements. JOURNAL OF SYNCHROTRON RADIATION[J]. 2017, 第 6 作者 通讯作者 24(4): 781-786, http://www.corc.org.cn/handle/1471x/2177289.
[43] Lin, QingPeng, Gao, ZengQiang, Geng, Zhi, Zhang, Heng, Dong, YuHui. Crystal structure of the putative cytoplasmic protein STM0279 (Hcp2) from Salmonella typhimurium. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS[J]. 2017, 第 5 作者 通讯作者 73(8): 463-468, http://www.corc.org.cn/handle/1471x/2176933.
[44] Hu, Haidai, Dong, Jiazhen, Liang, Deguang, Gao, Zengqiang, Bai, Lei, Sun, Rui, Hu, Hao, Zhang, Heng, Dong, Yuhui, Lan, Ke. Genome-Wide Mapping of the Binding Sites and Structural Analysis of Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 2 Reveal that It Is a DNA-Binding Transcription Factor. JOURNAL OF VIROLOGY[J]. 2016, 第 9 作者 通讯作者 90(3): 1158-1168, http://dx.doi.org/10.1128/JVI.01392-15.
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[59] Su, Feng, Lu, Liping, Feng, Sisi, Zhu, Miaoli, Gao, Zengqiang, Dong, Yuhui. Synthesis, structures and magnetic properties in 3d-electron-rich isostructural complexes based on chains with sole syn-anti carboxylate bridges. DALTON TRANSACTIONS[J]. 2015, 第 6 作者44(16): 7213-7222, http://ir.ihep.ac.cn/handle/311005/228299.
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[63] Zhang Jiulong, Zhang Heng, Liu Ying, Zhan Lihong, She Zhun, Dong Cheng, Dong Yuhui. Crystallization and preliminary X-ray study of TsiV3 from Vibrio cholerae. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS[J]. 2014, 第 7 作者70(3): 335-338, http://ir.ihep.ac.cn/handle/311005/224794.
[64] Yan JuanZhi, Zhu MiaoLi, Gao ZengQiang, Dong YuHui. Construction and Photoluminescence Properties of Zn(II)/Cd(II) Complexes with 4-Amino-3,5-propy1-1,2,4-triazole Ligand. CHINESE JOURNAL OF STRUCTURAL CHEMISTRY[J]. 2014, 第 4 作者33(8): 1207-1214, http://ir.ihep.ac.cn/handle/311005/224894.
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[67] Jiang, Ling, Gao, Zengqiang, Li, Yanhua, Wang, Shennan, Dong, Yuhui. Crystal structures and kinetic properties of enoyl-acyl carrier protein reductase broken vertical bar from Candidatus Liberib acterasiaticus. PROTEIN SCIENCE[J]. 2014, 第 5 作者 通讯作者 23(4): 366-377, http://dx.doi.org/10.1002/pro.2418.
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[71] Zhang, Jiulong, Zhang, Heng, Liu, Ying, Zhan, Lihong, She, Zhun, Dong, Cheng, Dong, Yuhui. Crystallization and preliminary X-ray study of TsiV3 from Vibrio cholerae. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS[J]. 2014, 第 7 作者70(Pt 3): 335-338, https://www.webofscience.com/wos/woscc/full-record/WOS:000332405600012.
[72] Peng, Shuxia, Zhou, Ke, Wang, Wenjia, Gao, Zengqiang, Dong, Yuhui, Liu, Quansheng. High-resolution crystal structure reveals a HEPN domain at the C-terminal region of S-cerevisiae RNA endonuclease Swt1. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2014, 第 5 作者453(4): 826-832, http://ir.ihep.ac.cn/handle/311005/224857.
[73] Wang Zixi, Li Lanfen, Dong YuHui, Su XiaoDong. Structural and biochemical characterization of MdaB from cariogenic Streptococcus mutans reveals an NADPH-specific quinone oxidoreductase. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY[J]. 2014, 第 3 作者70(4): 912-921, http://ir.ihep.ac.cn/handle/311005/224790.
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[76] Zhang, Jiulong, Zhang, Heng, Gao, Zengqiang, Hu, Haidai, Dong, Cheng, Dong, YuHui. Structural basis for recognition of the type VI spike protein VgrG3 by a cognate immunity protein. FEBS LETTERS[J]. 2014, 第 6 作者588(10): 1891-1898, https://www.doi.org/10.1016/j.febslet.2014.04.016.
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[110] Zhang, Yangli, Gao, Zengqiang, Zhang, Zhenzhen, Luo, Miao, Huang, Ailong, Dong, Yuhui, Wang, Deqiang. Cloning, purification, crystallization and preliminary X-ray studies of human a1-microglobulin. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS[J]. 2012, 第 6 作者68: 692-694, https://www.webofscience.com/wos/woscc/full-record/WOS:000305073600019.
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[115] Wei, Yong, Zhang, Heng, Gao, ZengQiang, Wang, WenJia, Shtykova, Eleonora V, Xu, JianHua, Liu, QuanSheng, Dong, YuHui. Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA. JOURNAL OF STRUCTURAL BIOLOGY[J]. 2012, 第 8 作者 通讯作者 179(1): 29-40, http://dx.doi.org/10.1016/j.jsb.2012.04.011.
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科研活动
科研项目
( 1 ) 基于同步辐射的蛋白质和复合体三维结构测定新技术研究, 主持, 国家级, 2009-01--2014-12
( 2 ) 综合同步辐射小角散射和晶体学解析蛋白质复合物结构的方法学研究, 主持, 国家级, 2010-01--2013-12
( 3 ) 与环境和纳米生物效应相关的蛋白质研究平台, 主持, 国家级, 2011-01--2012-01
( 4 ) 蛋白质生命周期过程及调控的分子机制, 参与, 国家级, 2012-01--2016-12
( 5 ) 基于自由电子X射线激光的结构解析技术, 主持, 部委级, 2014-01--2018-12
( 6 ) 蛋白质分拣与转运以及降解的结构生物学研究, 主持, 国家级, 2012-01--2016-12
( 7 ) 依托同步辐射光源的蛋白质晶体学前沿关键技术综合研究, 主持, 国家级, 2017-07--2022-06
( 2 ) 综合同步辐射小角散射和晶体学解析蛋白质复合物结构的方法学研究, 主持, 国家级, 2010-01--2013-12
( 3 ) 与环境和纳米生物效应相关的蛋白质研究平台, 主持, 国家级, 2011-01--2012-01
( 4 ) 蛋白质生命周期过程及调控的分子机制, 参与, 国家级, 2012-01--2016-12
( 5 ) 基于自由电子X射线激光的结构解析技术, 主持, 部委级, 2014-01--2018-12
( 6 ) 蛋白质分拣与转运以及降解的结构生物学研究, 主持, 国家级, 2012-01--2016-12
( 7 ) 依托同步辐射光源的蛋白质晶体学前沿关键技术综合研究, 主持, 国家级, 2017-07--2022-06
指导学生
已指导学生
高增强 博士研究生 070205-凝聚态物理
洪才浩 博士研究生 070205-凝聚态物理
孙少瑞 博士研究生 070205-凝聚态物理
许锐 博士研究生 070205-凝聚态物理
刘超培 博士研究生 070205-凝聚态物理
现指导学生
刘广峰 硕士研究生 070205-凝聚态物理
刘忠川 博士研究生 070205-凝聚态物理
曲昆 硕士研究生 070205-凝聚态物理
佘准 博士研究生 070205-凝聚态物理