基本信息
丁侃 男 博导 上海药物研究所
电子邮件:kding@mail.shcnc.ac.cn
通信地址:上海浦东张江祖冲之路555号
邮政编码:201203

研究领域

    运用有机化学、细胞生物学、分子生物学,中药学等化学与生物学交叉学科手段,进行生物体内多糖、寡糖、蛋白聚糖结构与功能研究,在此基础上致力于重大疾病的药物研发。

招生信息

   
招生专业
100706-药理学
100701-药物化学
招生方向


教育背景

   
学历
-- 研究生
学位
-- 博士

专利与奖励

   
专利成果
[1] 丁侃. 一种天葵子糖肽、其制备方法及用途. CN202310023083.5, 2023-01-05.
[2] 丁侃. 一种月季花中新均一多糖的制备及其在抗纤维化药物中的应用. CN202211651073.8, 2022-12-21.
[3] 丁侃. 铁皮石斛花中新聚糖的制备及其调节肠道菌群的新应用. CN202211651085.0, 2022-12-21.
[4] 丁侃. 一种芫花新聚糖的制备及其新用途. CN202211651316.8, 2022-12-21.
[5] 丁侃. 海藻硫酸多糖及其制备方法和用途. CN202211624541.2, 2022-12-16.
[6] 丁侃. 一种栀子多糖及其制备方法及用途. CN202210314228.2, 2022-03-28.
[7] 丁侃. 一种合欢花非均一多糖,其制备方法及用途. CN202210215654.0, 2022-03-07.
[8] 丁侃. 丁香多糖、其制备方法及应用. CN202111230082.5, 2021-10-21.

出版信息

   
发表论文
[1] JOURNAL OF HEPATOLOGY. 2023, 第 10 作者  通讯作者  
[2] Pan, Haoyu, Chen, Xia, Wang, PeiPei, Peng, Junfeng, Li, Judong, Ding, Kan. Effects of Nemacystus decipiens polysaccharide on mice with antibiotic associated diarrhea and colon inflammation. FOOD & FUNCTION[J]. 2023, 第 6 作者  通讯作者  14(3): 1627-1635, 
[3] Jiang, Lan, Zhang, Tianji, Lu, Hongzhong, Li, Saijuan, Lv, Kangjie, Tuffour, Alex, Zhang, Lixin, Ding, Kan, Li, JinPing, Li, Hongmei, Liu, Xueting. Heparin mimetics as potential intervention for COVID-19 and their bio-manufacturing. SYNTHETIC AND SYSTEMS BIOTECHNOLOGY. 2023, 第 8 作者  通讯作者  8(1): 11-19, http://lib.cqvip.com/Qikan/Article/Detail?id=7109432344.
[4] Saijuan Li, Tingting Li, Binqiang Wang, Chang Wen, Meixia Li, Kan Ding. A structure defined pectin SA02B from Semiaquilegia adoxoides is metabolized by human gut microbes. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2023, 第 6 作者  通讯作者  234: 123673, http://dx.doi.org/10.1016/j.ijbiomac.2023.123673.
[5] Sun, Chuanxin, Chen, Xia, Yang, Shangpo, Jin, Can, Ding, Kan, Chen, Chang. LBP1C-2 from Lycium barbarum alleviated age-related bone loss by targeting BMPRIA/BMPRII/Noggin. CARBOHYDRATE POLYMERS[J]. 2023, 第 5 作者  通讯作者  310: http://dx.doi.org/10.1016/j.carbpol.2023.120725.
[6] 李赛娟, 苏娟, 靳灿, 丁侃. 中药抗冠状病毒的作用机制及临床应用研究进展. 中草药[J]. 2023, 第 4 作者54(1): 334-345, http://lib.cqvip.com/Qikan/Article/Detail?id=7109027509.
[7] 伍东立, 乔新华, 韩文生, 谢婷, 时畅, 黄雨云飞, 孙传鑫, 丁侃, 陈畅. 枸杞子多糖提取物LBP1C通过激活TFEB延缓衰老. 生物化学与生物物理进展[J]. 2023, 第 8 作者50(8): 1926-1936, http://www.pibb.ac.cn/pibbcn/article/abstract/20230219?st=article_issue.
[8] JOURNAL OF HEPATOLOGY. 2023, 第 10 作者  通讯作者  
[9] Liao, Wenfeng, Hu, Xiaodong, Du, Zhenyun, Wang, Peipei, Ding, Kan. A homogalacturonan from Lonicera japonica Thunb. disrupts angiogenesis via epidermal growth factor receptor and Delta-like 4 associated signaling. GLYCOCONJUGATE JOURNAL[J]. 2022, 第 5 作者  通讯作者  39(6): 725-735, 
[10] Li, Saijuan, Jin, Can, Gao, Pengcheng, Zhou, Wanqi, Xiao, Rongrong, Zhang, Zhenqiang, Liao, Wenfeng, Ding, Kan. A Novel Pectin-Like Glycopeptide Isolated from the Fruit of Fructus Mori Impedes Aggregation and Production of A beta(42). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2022, 第 8 作者  通讯作者  70(32): 9908-9918, 
[11] Hu, Chaoyu, Wu, Shengjie, He, Fei, Cai, Deqin, Xu, Zhuojia, Ma, Wenjing, Liu, Yating, Wei, Bangguo, Li, Tiehai, Ding, Kan. Convergent Synthesis and Anti-Pancreatic Cancer Cell Growth Activity of a Highly Branched Heptadecasaccharide from Carthamus tinctorius. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, 第 10 作者  通讯作者  61(32): https://www.doi.org/10.1002/anie.202202554.
[12] Li Yan, Yang Qingran, Yang Chi, Ding Kan, Xu Guangzhou. Evaluation of the predominant bacteria and proinflammatory cytokine expressions in odontogenic cysts. ACTA BIOCHIMICA ET BIOPHYSICA SINICA[J]. 2022, 第 4 作者54(3): 409-411, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7254917&detailType=1.
[13] BingbingLiYingHongYuGuShengjieYeKailiHuJianYaoKanDingAihuaZhaoWeiJiaHoukaiLi. Functional Metabolomics Reveals thatAstragalusPolysaccharides Improve Lipids Metabolism through Microbial Metabolite 2-Hydroxybutyric Acid in Obese Mice. Engineering[J]. 2022, 9(2): 111-122, https://journal.hep.com.cn/engi/EN/10.1016/j.eng.2020.05.023.
[14] Huang, Lulin, Zeng, Hui, Jin, Can, Ma, Xiaonan, Zhang, Yiwen, Huang, Chunfan, Du, Zhenyun, Ding, Kan. Sulfated galactoglucan impedes xenografted lung cancer cell growth by blocking angiogenesis via binding BMPRs. CARBOHYDRATE POLYMERS[J]. 2022, 第 8 作者  通讯作者  289: http://dx.doi.org/10.1016/j.carbpol.2022.119412.
[15] Zhang, Shihai, Pei, Rongjuan, Li, Meixia, Su, Haixia, Sun, Hao, Ding, Yaqi, Su, Minbo, Huang, Chunfan, Chen, Xia, Du, Zhenyun, Jin, Can, Zang, Yi, Li, Jia, Xu, Yechun, Chen, Xinwen, Zhang, Bo, Ding, Kan. Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection. CARBOHYDRATE POLYMERS[J]. 2022, 第 17 作者  通讯作者  275: 118779-118779, http://dx.doi.org/10.1016/j.carbpol.2021.118779.
[16] Huang, Chunfan, Jing, Xiaoqi, Wu, Qianhu, Ding, Kan. Novel pectin-like polysaccharide from Panax notoginseng attenuates renal tubular cells fibrogenesis induced by TGF-beta. CARBOHYDRATE POLYMERS[J]. 2022, 第 4 作者  通讯作者  276: http://dx.doi.org/10.1016/j.carbpol.2021.118772.
[17] Pan, HaoYu, Zhang, ChunQian, Zhang, XiuQi, Zeng, Hui, Dong, ChunHong, Chen, Xia, Ding, Kan. A galacturonan from Dioscorea opposita Thunb. regulates fecal and impairs IL-1 and IL-6 expression in diarrhea mice. GLYCOCONJUGATE JOURNAL[J]. 2022, 第 7 作者  通讯作者  39(1): 131-141, http://dx.doi.org/10.1007/s10719-022-10053-z.
[18] 卞娅, 葛广波, 丁侃. 中药多糖抗病毒机制研究进展. 上海中医药大学学报[J]. 2021, 第 3 作者35(5): 89-96, http://lib.cqvip.com/Qikan/Article/Detail?id=7105942414.
[19] Guo, Ciliang, Wang, Yeqing, Zhang, Shihai, Zhang, Xiuqi, Du, Zhenyun, Li, Meixia, Ding, Kan. Crataegus pinnatifida polysaccharide alleviates colitis via modulation of gut microbiota and SCFAs metabolism. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2021, 第 7 作者  通讯作者  181: 357-368, http://dx.doi.org/10.1016/j.ijbiomac.2021.03.137.
[20] 王莹, 金红宇, 丁侃, 马双成. 中药多糖质量控制体系初探. 药物分析杂志[J]. 2021, 第 3 作者41(10): 1670-1680, http://lib.cqvip.com/Qikan/Article/Detail?id=7106198224.
[21] Ke Chen, Zhongqiang Wang, Kan Ding, Yongzheng Chen, Yasuhisa Asano. Recent progress on discovery and research of aldoxime dehydratases. GREEN SYNTHESIS AND CATALYSIS[J]. 2021, 第 3 作者2(2): 179-186, http://dx.doi.org/10.1016/j.gresc.2021.04.001.
[22] Meixia Li, Ciliang Guo, Yeqing Wang, Zhenyun Du, Sheng Chen, Yulan Wang, Kan Ding. Nostoc sphaeroids Kütz polysaccharide and powder enrich a core bacterial community on C57BL/6j mice. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2020, 第 7 作者  通讯作者  162: 1734-1742, http://dx.doi.org/10.1016/j.ijbiomac.2020.08.026.
[23] Tao, Hong, Chen, Xia, Du, Zhenyun, Ding, Kan. Corn silk crude polysaccharide exerts anti-pancreatic cancer activity by blocking the EGFR/PI3K/AKT/CREB signaling pathway. FOOD & FUNCTION[J]. 2020, 第 4 作者  通讯作者  11(8): 6961-6970, http://dx.doi.org/10.1039/d0fo00403k.
[24] Wang, Yeqing, Shao, Saicong, Guo, Ciliang, Zhang, Shihai, Li, Meixia, Ding, Kan. The homogenous polysaccharide SY01-23 purified from leaf of Morus alba L. has bioactivity on human gut Bacteroides ovatus and Bacteroides cellulosilyticus. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 第 6 作者  通讯作者  158: 698-707, http://dx.doi.org/10.1016/j.ijbiomac.2020.05.009.
[25] Bian, Youcheng, Zeng, Hui, Tao, Hong, Huang, Lulin, Du, Zhenyun, Wang, Jiao, Ding, Kan. A pectin-like polysaccharide from Polygala tenuifolia inhibits pancreatic cancer cell growth in vitro and in vivo by inducing apoptosis and suppressing autophagy. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 第 7 作者  通讯作者  162: 107-115, http://dx.doi.org/10.1016/j.ijbiomac.2020.06.054.
[26] Wang, Ying, Xiao, Fei, Jin, Can, Wang, Wucheng, Chen, Xia, Liu, Qin, Ding, Kan. The impact of structural modification of sulfated polysaccharides on bone morphogenic protein 2 and inhibition of endothelial cell angiogenesis. CARBOHYDRATE RESEARCH[J]. 2020, 第 7 作者  通讯作者  496: http://dx.doi.org/10.1016/j.carres.2020.108093.
[27] Zeng, Hui, Huang, Lulin, Tao, Hong, Zhang, Yiwen, Ding, Kan. Structural elucidation of a pectin from roots of Polygala tenuifolia and its neuritogenesis inducing activity in PC12 cells. CARBOHYDRATE POLYMERS[J]. 2020, 第 5 作者  通讯作者  236: http://dx.doi.org/10.1016/j.carbpol.2020.116048.
[28] Zeng, Hui, Li, Piaopiao, Zhou, Lishuang, Ding, Kan. A novel pectin from Polygala tenuifolia blocks A beta(42) aggregation and production by enhancing insulin-degradation enzyme and neprilysin. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 第 4 作者  通讯作者  161: 35-43, http://dx.doi.org/10.1016/j.ijbiomac.2020.05.212.
[29] Li XueYing, Tao Hong, Jin Can, Du ZhenYun, Liao WenFeng, Tang QingJiu, Ding Kan. Cordycepin inhibits pancreatic cancer cell growth in vitro and in vivo via targeting FGFR2 and blocking ERK signaling. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2020, 第 7 作者  通讯作者  18(5): 345-355, http://lib.cqvip.com/Qikan/Article/Detail?id=7102093681.
[30] Yue Han, Zeng Hui, Ding Kan. A review of isolation methods, structure features and bioactivities of polysaccharides from Dendrobium species. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2020, 第 3 作者  通讯作者  18(1): 1-27, http://lib.cqvip.com/Qikan/Article/Detail?id=7101130879.
[31] Zhou, Yue, Duan, Yanhong, Huang, Shichao, Zhou, Xuan, Zhou, Lishuang, Hu, Tingting, Yang, Yongfeng, Lu, Jing, Ding, Kan, Guo, Dean, Cao, Xiaohua, Pei, Gang. Polysaccharides from Lycium barbarum ameliorate amyloid pathology and cognitive functions in APP/PS1 transgenic mice. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 第 9 作者  通讯作者  144: 1004-1012, http://dx.doi.org/10.1016/j.ijbiomac.2019.09.177.
[32] Hui Zeng, Piaopiao Li, Lishuang Zhou, Kan Ding. A novel pectin from Polygala tenuifolia blocks Aβ42 aggregation and production by enhancing insulin-degradation enzyme and neprilysin. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2020, 第 4 作者  通讯作者  161: 35-43, http://dx.doi.org/10.1016/j.ijbiomac.2020.05.212.
[33] Li, Meixia, Yue, Han, Wang, Yeqing, Guo, Ciliang, Du, Zhenyun, Jin, Can, Ding, Kan. Intestinal microbes derived butyrate is related to the immunomodulatory activities of Dendrobium officinale polysaccharide. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 第 7 作者  通讯作者  149: 717-723, http://dx.doi.org/10.1016/j.ijbiomac.2020.01.305.
[34] Li, Meixia, Guo, Ciliang, Wang, Yeqing, Du, Zhenyun, Chen, Sheng, Wang, Yulan, Ding, Kan. Nostoc sphaeroids Kutz polysaccharide and powder enrich a core bacterial community on C57BL/6j mice. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 第 7 作者  通讯作者  162: 1734-1742, http://dx.doi.org/10.1016/j.ijbiomac.2020.08.026.
[35] Zhang, Li, Zhang, Jingyu, Ren, Biao, Lu, Wanying, Hou, Chengjian, Wang, Jian, Ma, Xiaolong, Ma, Rong, Liu, Mei, Liu, Zhiheng, Li, JinPing, Ding, Kan, Dai, Huanqin, Zhang, Lixin, Liu, Xueting. Characterization of anti-BCG benzalphaanthraquinones and new siderophores from a *** desert-isolated rare actinomycete Nocardia sp. XJ31. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY[J]. 2020, 第 12 作者104(19): 8267-8278, http://dx.doi.org/10.1007/s00253-020-10842-2.
[36] Guo, Ciliang, Zhang, Shihai, Wang, Yeqing, Li, Meixia, Ding, Kan. Isolation and structure characterization of a polysaccharide from Crataegus pinnatifida and its bioactivity on gut microbiota. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2020, 第 5 作者  通讯作者  154: 82-91, http://dx.doi.org/10.1016/j.ijbiomac.2020.03.058.
[37] Zang, Yi, Ding, Kan, Wang, Guanzhen. Galectin3 INHIBITOR X2 ALLEVIATES LIVER FIBROSIS VIA SURPPRESSION OF INFLAMMATION AND HEPATIC STELLATE CELLS ACTIVATION. HEPATOLOGY[J]. 2019, 第 2 作者70: 885A-885A, https://www.webofscience.com/wos/woscc/full-record/WOS:000488653503155.
[38] Zhang, ChunQian, Chen, Xia, Ding, Kan. Structural characterization of a galactan from Dioscorea opposita Thunb. and its bioactivity on selected Bacteroides strains from human gut microbiota. CARBOHYDRATE POLYMERS[J]. 2019, 第 3 作者  通讯作者  218: 299-306, http://dx.doi.org/10.1016/j.carbpol.2019.04.084.
[39] Zhang, Shihai, Zhang, Chunqian, Li, Meixia, Chen, Xia, Ding, Kan. Structural elucidation of a glucan from Crataegus pinnatifida and its bioactivity on intestinal bacteria strains. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2019, 第 5 作者  通讯作者  128: 435-443, http://dx.doi.org/10.1016/j.ijbiomac.2019.01.158.
[40] Wang, Zheng, Jin, Can, Li, Xueying, Ding, Kan. Sulfated polysaccharide JCS1S2 inhibits angiogenesis via targeting VEGFR2/VEGF and blocking VEGFR2/Erk/VEGF signaling. CARBOHYDRATE POLYMERS[J]. 2019, 第 4 作者  通讯作者  207: 502-509, http://dx.doi.org/10.1016/j.carbpol.2018.11.091.
[41] Yao, Yanli, Zhou, Lishuang, Liao, Wenfeng, Chen, Huanjun, Du, Zhenyun, Shao, Chenghao, Wang, Peipei, Ding, Kan. HH1-1, a novel Galectin-3 inhibitor, exerts anti-pancreatic cancer activity by blocking Galectin-3/EGFR/AKT/FOXO3 signaling pathway. CARBOHYDRATE POLYMERS[J]. 2019, 第 8 作者  通讯作者  204: 111-123, http://dx.doi.org/10.1016/j.carbpol.2018.10.008.
[42] Zeng, Hui, Huang, Lulin, Zhou, Lishuang, Wang, Peipei, Chen, Xia, Ding, Kan. A galactoglucan isolated from of Cistanche deserticola Y. C. Ma. and its bioactivity on intestinal bacteria strains. CARBOHYDRATE POLYMERS[J]. 2019, 第 6 作者  通讯作者  223: http://dx.doi.org/10.1016/j.carbpol.2019.115038.
[43] Zhang, Shihai, He, Fei, Chen, Xia, Ding, Kan. Isolation and structural characterization of a pectin from Lycium ruthenicum Murr and its anti-pancreatic ductal adenocarcinoma cell activity. CARBOHYDRATE POLYMERS[J]. 2019, 第 4 作者  通讯作者  223: http://dx.doi.org/10.1016/j.carbpol.2019.115104.
[44] Fu, Youli, Shi, Lei, Ding, Kan. Structure elucidation and anti-tumor activity in vivo of a polysaccharide from spores of Ganoderma lucidum (Fr.) Karst. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2019, 第 3 作者141: 693-699, https://www.webofscience.com/wos/woscc/full-record/WOS:000506713000072.
[45] 王恒禹, 罗云凤, 姜京华, 丁侃, 董艳萍. 玉米须多糖的提取纯化及结构研究. 首都师范大学学报:自然科学版[J]. 2019, 第 4 作者40(1): 44-49, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFDLAST2019&filename=SDSX201901009&v=MjI4NDFyQ1VSN3FmYitacEZDcmdWYnpMTmluWWRyRzRIOWpNcm85RmJZUjhlWDFMdXhZUzdEaDFUM3FUcldNMUY=.
[46] Qu, Huanhuan, Li, Baixue, Yang, Jingyi, Liang, Huaiwen, Li, Meixia, Ding, Kan. Design, Synthesis and Bioactivity of Core 1 O-glycan and its Derivative on Human Gut Microbiota. LETTERS IN DRUG DESIGN & DISCOVERY[J]. 2019, 第 6 作者  通讯作者  16(12): 1348-1353, http://dx.doi.org/10.2174/1570180816666181218143207.
[47] Zhou, Lishuang, Liao, Wenfeng, Zeng, Hui, Yao, Yanli, Chen, Xia, Ding, Kan. A pectin from fruits of Lycium barbarum L. decreases Beta-amyloid peptide production through modulating APP processing. CARBOHYDRATE POLYMERS[J]. 2018, 第 6 作者  通讯作者  201: 65-74, https://www.webofscience.com/wos/woscc/full-record/WOS:000445030100008.
[48] Zhou, Lishuang, Liao, Wenfeng, Chen, Xia, Yue, Han, Li, Saijuan, Ding, Kan. An arabinogalactan from fruits of Lycium barbarum L. inhibits production and aggregation of A beta(42). CARBOHYDRATE POLYMERS[J]. 2018, 第 6 作者  通讯作者  195: 643-651, https://www.webofscience.com/wos/woscc/full-record/WOS:000433204900073.
[49] Zhou, Lishuang, Huang, Lulin, Yue, Han, Ding, Kan. Structure analysis of a heteropolysaccharide from fruits of Lycium barbarum L. and anti-angiogenic activity of its sulfated derivative. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2018, 第 4 作者  通讯作者  108: 47-55, http://dx.doi.org/10.1016/j.ijbiomac.2017.11.111.
[50] Meng, Yan, Shi, Xiaodan, Cai, Liqin, Zhang, Shihai, Ding, Kan, Nie, Shaoping, Luo, Chuanfu, Xu, Xiaojuan, Zhang, Lina. Triple-Helix Conformation of a Polysaccharide Determined with Light Scattering, AFM, and Molecular Dynamics Simulation. MACROMOLECULES[J]. 2018, 第 5 作者51(24): 10150-10159, https://www.webofscience.com/wos/woscc/full-record/WOS:000454567400012.
[51] Han, Kun, Jin, Can, Chen, Huanjun, Wang, Peipei, Yu, Mei, Ding, Kan. Structural characterization and anti-A549 lung cancer cells bioactivity of a polysaccharide from Houttuynia cordata. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2018, 第 6 作者  通讯作者  120: 288-296, http://dx.doi.org/10.1016/j.ijbiomac.2018.08.061.
[52] Sun, Feifei, Liu, Yinyin, Wang, Dongdong, Wang, Zhaojie, Mu, Haibo, Wang, Feng, Ding, Kan, Duan, Jinyou. A novel photocleavable heparin derivative with light controllable anticoagulant activity. CARBOHYDRATE POLYMERS[J]. 2018, 第 7 作者184: 191-198, http://dx.doi.org/10.1016/j.carbpol.2017.12.057.
[53] Liu, Qin, Fang, Jianping, Wang, Peipei, Du, Zhenyun, Li, Yanling, Wang, Shunchun, Ding, Kan. Characterization of a pectin from Lonicera japonica Thunb. and its inhibition effect on A beta(42) aggregation and promotion of neuritogenesis. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2018, 第 7 作者  通讯作者  107: 112-120, https://www.webofscience.com/wos/woscc/full-record/WOS:000423892200013.
[54] Gu, Dan, Huang, Lulin, Chen, Xia, Wu, Qianhu, Ding, Kan. Structural characterization of a galactan from Ophiopogon japonicus and anti-pancreatic cancer activity of its acetylated derivative. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2018, 第 5 作者  通讯作者  113: 907-915, http://dx.doi.org/10.1016/j.ijbiomac.2018.03.019.
[55] Yao, Yanli, Yao, Jian, Du, Zhenyun, Wang, Peipei, Ding, Kan. Structural elucidation and immune-enhancing activity of an arabinogalactan from flowers of Carthamus tinctorius L.. CARBOHYDRATE POLYMERS[J]. 2018, 第 5 作者  通讯作者  202: 134-142, http://dx.doi.org/10.1016/j.carbpol.2018.08.098.
[56] Lishuang Zhou, Wenfeng Liao, Hui Zeng, Yanli Yao, Xia Chen, Kan Ding. A pectin from fruits of Lycium barbarum L. decreases β-amyloid peptide production through modulating APP processing. CARBOHYDRATE POLYMERS. 2018, 第 6 作者  通讯作者  201: 65-74, http://dx.doi.org/10.1016/j.carbpol.2018.08.050.
[57] Li, Saijuan, Li, Meixia, Yue, Han, Zhou, Lishuang, Huang, Lulin, Du, Zhenyun, Ding, Kan. Structural elucidation of a pectic polysaccharide from Fructus Mori and its bioactivity on intestinal bacteria strains. CARBOHYDRATE POLYMERS[J]. 2018, 第 7 作者  通讯作者  186: 168-175, http://dx.doi.org/10.1016/j.carbpol.2018.01.026.
[58] Zheng, Changping, Qu, Huanhuan, Liao, Wenfeng, Bavaro, Teodora, Terreni, Marco, Sollogoub, Matthieu, Ding, Kan, Zhang, Yongmin. Chemoenzymatically synthesized GM3 analogues as potential therapeutic agents to recover nervous functionality after injury by inducing neurite outgrowth. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2018, 第 7 作者  通讯作者  146: 613-620, http://dx.doi.org/10.1016/j.ejmech.2018.01.079.
[59] Zhang, L, Wang, P, Qin, Y, Cong, Q, Shao, C, Du, Z, Ni, X, Li, P, Ding, K. RN1, a novel galectin-3 inhibitor, inhibits pancreatic cancer cell growth in vitro and in vivo via blocking galectin-3 associated signaling pathways. ONCOGENE[J]. 2017, 36(9): 1297-1308, https://www.webofscience.com/wos/woscc/full-record/WOS:000395861300013.
[60] Yue, Han, Liu, Yanqiu, Qu, Huanhuan, Ding, Kan. Structure analysis of a novel heteroxylan from the stem of Dendrobium officinale and anti-angiogenesis activities of its sulfated derivative. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2017, 第 4 作者  通讯作者  103: 533-542, http://dx.doi.org/10.1016/j.ijbiomac.2017.05.097.
[61] Wang, Jiwen, Liu, Han, Shen, Xiaokun, Wang, Yueqi, Zhang, Dexiang, Shen, Sheng, Suo, Tao, Pan, Hongtao, Ming, Yue, Ding, Kan, Liu, Houbao. Long non-coding RNA expression profiles in gallbladder carcinoma identified using microarray analysis. ONCOLOGY LETTERS[J]. 2017, 第 10 作者  通讯作者  13(5): 3508-3516, https://www.webofscience.com/wos/woscc/full-record/WOS:000401129800091.
[62] Huang, Shichao, Mao, Jianxin, Ding, Kan, Zhou, Yue, Zeng, Xianglu, Yang, Wenjuan, Wang, Peipei, Zhao, Cun, Yao, Jian, Xia, Peng, Pei, Gang. Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease. STEM CELL REPORTS[J]. 2017, 第 3 作者8(1): 84-94, http://dx.doi.org/10.1016/j.stemcr.2016.12.007.
[63] Qiu, Yuanhao, Hou, Yilin, Sun, Feifei, Chen, Peng, Wang, Dongdong, Mu, Haibo, Zhang, Xiaoli, Ding, Kan, Duan, Jinyou. Hyaluronic acid conjugation facilitates clearance of intracellular bacterial infections by streptomycin with neglectable nephrotoxicity. GLYCOBIOLOGY[J]. 2017, 第 8 作者27(9): 861-867, https://www.webofscience.com/wos/woscc/full-record/WOS:000409143900008.
[64] Liu, Yanqiu, Ding, Yaqi, Ye, Min, Zhu, Tao, Tian, Danbi, Ding, Kan. A Novel Heterogalactan from Antrodia camphorata and Anti-Angiogenic Activity of Its Sulfated Derivative. POLYMERS[J]. 2017, 第 6 作者  通讯作者  9(6): https://www.webofscience.com/wos/woscc/full-record/WOS:000404218500043.
[65] Cai, Deqin, Xun, Chaochao, Tang, Feng, Tian, Xiaobo, Yang, Liyun, Ding, Kan, Li, Wenzhe, Le, Zhiping, Huang, Wei. Glycoconjugate probes containing a core-fucosylated N-glycan trisaccharide for fucose lectin identification and purification. CARBOHYDRATE RESEARCH. 2017, 第 6 作者449: 143-152, http://dx.doi.org/10.1016/j.carres.2017.07.011.
[66] Jin, Can, Du, Zhenyun, Lin, Liyan, Zhou, Lishuang, Li, Saijuan, Liu, Qin, Ding, Kan. Structural Characterization of Mannoglucan from Dendrobium nobile Lindl and the Neuritogenesis-Induced Effect of Its Acetylated Derivative on PC-12 Cells. POLYMERS[J]. 2017, 第 7 作者  通讯作者  9(9): https://doaj.org/article/b95b87dcade844239edea63ff9b5a540.
[67] Cai, Deqin, Yao, Yanli, Tang, Yubo, Wang, Zheng, Shi, Wei, Huang, Wei, Ding, Kan. A Concise Synthesis of Three Branches Derived from Polysaccharide RN1 and Anti-Pancreatic Cancer Activity Study. POLYMERS[J]. 2017, 第 7 作者  通讯作者  9(10): http://dx.doi.org/10.3390/polym9100536.
[68] Cai, Deqin, Guan, Dongliang, Ding, Kan, Huang, Wei. Regioselective protection of xylose for efficient synthesis of arabino-alpha-1,3-xylosides. TETRAHEDRON LETTERS[J]. 2017, 第 3 作者  通讯作者  58(45): 4293-4295, https://www.webofscience.com/wos/woscc/full-record/WOS:000414107300017.
[69] Liu Qin, Wang ShunChun, Ding Kan. Research advances in the treatment of Alzheimer's disease with polysaccharides from traditional Chinese medicine. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2017, 第 3 作者  通讯作者  15(9): 641-652, http://dx.doi.org/10.1016/S1875-5364(17)30093-6.
[70] Sun, Xiaoming, Pan, Qin, Yuan, Chunhui, Wang, Qilong, Tang, XiaoLei, Ding, Kan, Zhou, Xiang, Zhang, XiaoLian. A Single ssDNA Aptamer Binding to Mannose-Capped Lipoarabinomannan of Bacillus Calmette-Guerin Enhances Immunoprotective Effect against Tuberculosis. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2016, 第 6 作者138(36): 11680-11689, https://www.webofscience.com/wos/woscc/full-record/WOS:000383410700041.
[71] Lin, Liyan, Wang, Peipei, Du, Zhenyun, Wang, Wucheng, Cong, Qifei, Zheng, Changping, Jin, Can, Ding, Kan, Shao, Chenghao. Structural elucidation of a pectin from flowers of Lonicera japonica and its antipancreatic cancer activity. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2016, 第 8 作者  通讯作者  88: 130-137, http://dx.doi.org/10.1016/j.ijbiomac.2016.03.025.
[72] Shen, Xiaokun, Li, Jie, Liao, Wenfeng, Wang, Jiwen, Chen, Huanjun, Yao, Yanli, Liu, Houbao, Ding, Kan. microRNA-149 targets caspase-2 in glioma progression. ONCOTARGET[J]. 2016, 第 8 作者  通讯作者  7(18): 26388-26399, http://dx.doi.org/10.18632/oncotarget.8506.
[73] Wang, Jiwen, Yao, Yanli, Ming, Yue, Shen, Sheng, Wu, Nan, Liu, Jiaqi, Liu, Han, Suo, Tao, Pan, Hongtao, Zhang, Dexiang, Ding, Kan, Liu, Houbao. Downregulation of stathmin 1 in human gallbladder carcinoma inhibits tumor growth in vitro and in vivo. SCIENTIFIC REPORTS[J]. 2016, 第 11 作者  通讯作者  6: 
[74] Wang, Wucheng, Chen, Huanjun, Zhang, Lei, Qin, Yi, Cong, Qifei, Wang, Peipei, Ding, Kan. A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting bone morphogenetic protein 4. CARBOHYDRATE POLYMERS[J]. 2016, 第 7 作者  通讯作者  144: 305-314, http://dx.doi.org/10.1016/j.carbpol.2016.02.068.
[75] Cong, Qifei, Chen, Huanjun, Liao, Wenfeng, Xiao, Fei, Wang, Peipei, Qin, Yi, Dong, Qun, Ding, Kan. Structural characterization and effect on anti-angiogenic activity of a fucoidan from Sargassum fusiforme. CARBOHYDRATE POLYMERS[J]. 2016, 第 8 作者136: 899-907, http://dx.doi.org/10.1016/j.carbpol.2015.09.087.
[76] Lin Liyan, Wang Peipei, Du Zhenyun, Wang Wucheng, Cong Qifei, Zheng Changping, Jin Can, Ding Kan, Shao Chenghao. Structural elucidation of a pectin from flowers of Lonicera japonica and its antipancreatic cancer activity. INTERNATIONALJOURNALOFBIOLOGICALMACROMOLECULES[J]. 2016, 第 8 作者
[77] Kan Ding. A fucoidan from Nemacystus decipiens disrupts angiogenesis through targeting BMP4. Carbohydr. Polym. 2016, 第 1 作者  通讯作者  
[78] Kan Ding. microRNA-149 targets caspase-2 in glioma progression. Oncotarget. Oncotarget. 2016, 第 1 作者  通讯作者  
[79] Chen, Huanjun, Cong, Qifei, Du, Zhenyun, Liao, Wenfeng, Zhang, Lei, Yao, Yanli, Ding, Kan. Sulfated fucoidan FP08S2 inhibits lung cancer cell growth in vivo by disrupting angiogenesis via targeting VEGFR2/VEGF and blocking VEGFR2/Erk/VEGF signaling. CANCER LETTERS[J]. 2016, 第 7 作者  通讯作者  382(1): 44-52, http://dx.doi.org/10.1016/j.canlet.2016.08.020.
[80] 张玲芝, 姜猛, 丁侃. 改性果胶的研究进展. 医药[J]. 2015, 第 3 作者281-282, http://lib.cqvip.com/Qikan/Article/Detail?id=664641306.
[81] Cheng CHEN, Yi QIN, Jian-ping FANG, Xin-yan NI, Jian YAO, Hai-ying WANG, Kan DING. WSS25, a sulfated polysaccharide, inhibits RANKL-induced mouse osteoclast formation by blocking SMAD/ID1 signaling. 中国药理学报:英文版[J]. 2015, 第 7 作者1053-1064, http://lib.cqvip.com/Qikan/Article/Detail?id=665982832.
[82] Chen, Cheng, Qin, Yi, Fang, Jianping, Ni, Xinyan, Yao, Jian, Wang, Haiying, Ding, Kan. WSS25, a sulfated polysaccharide, inhibits RANKL-induced mouse osteoclast formation by blocking SMAD/ID1 signaling. ACTA PHARMACOLOGICA SINICA[J]. 2015, 第 7 作者36(9): 1053-1064, http://lib.cqvip.com/Qikan/Article/Detail?id=665982832.
[83] Kan Ding. WSS25, a sulfated polysaccharide, inhibits RANKL-inducted osteoclast formation through blocking SMAD/ID1 signaling. Acta Pharmacol Sin. 2015, 第 1 作者  通讯作者  
[84] Qin, Yi, Ke, Jiyuan, Gu, Xin, Fang, Jianping, Wang, Wucheng, Cong, Qifei, Li, Jie, Tan, Jinzhi, Brunzelle, Joseph S, Zhang, Chenghai, Jiang, Yi, Melcher, Karsten, Li, Jinping, Xu, H Eric, Ding, Kan. Structural and Functional Study of D-Glucuronyl C5-epimerase. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2015, 第 15 作者290(8): 4620-4630, http://dx.doi.org/10.1074/jbc.M114.602201.
[85] Zheng, Changping, Dong, Qun, Chen, Huanjun, Cong, Qifei, Ding, Kan. Structural characterization of a polysaccharide from Chrysanthemum morifolium flowers and its antioxidant activity. CARBOHYDRATE POLYMERS[J]. 2015, 第 5 作者130: 113-121, http://dx.doi.org/10.1016/j.carbpol.2015.05.004.
[86] Wang, Peipei, Zhang, Lei, Yao, Jian, Shi, Yikang, Li, Ping, Ding, Kan. An arabinogalactan from flowers of Panax notoginseng inhibits angiogenesis by BMP2/Smad/Id1 signaling. CARBOHYDRATE POLYMERS[J]. 2015, 第 6 作者121: 328-335, http://dx.doi.org/10.1016/j.carbpol.2014.11.073.
[87] Xiao, F, Qiu, H, Cui, H, Ni, X, Li, J, Liao, W, Lu, L, Ding, K. MicroRNA-885-3p inhibits the growth of HT-29 colon cancer cell xenografts by disrupting angiogenesis via targeting BMPR1A and blocking BMP/Smad/Id1 signaling. ONCOGENE[J]. 2015, 34(15): 1968-1978, https://www.webofscience.com/wos/woscc/full-record/WOS:000352725600011.
[88] Xiong, Xiuming, Chen, Zhaoqiang, Cossins, Benjamin P, Xu, Zhijian, Shao, Qiang, Ding, Kai, Zhu, Weiliang, Shi, Jiye. Force fields and scoring functions for carbohydrate simulation. CARBOHYDRATE RESEARCH[J]. 2015, 401: 73-81, http://dx.doi.org/10.1016/j.carres.2014.10.028.
[89] Zheng, Changping, Dong, Qun, Du, Zhenyun, Wang, Peipei, Ding, Kan. Structural elucidation of a polysaccharide from Chrysanthemum morifolium flowers with anti-angiogenic activity. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2015, 第 5 作者79: 674-680, http://dx.doi.org/10.1016/j.ijbiomac.2015.04.026.
[90] Shen, Xiaokun, Xie, Bojian, Ma, Zhaosheng, Yu, Wenjie, Wang, Wenmin, Xu, Dong, Yan, Xinqiang, Chen, Beibei, Yu, Longyao, Li, Jicheng, Chen, Xiaobing, Ding, Kan, Cao, Feilin. Identification of novel long non-coding RNAs in triple-negative breast cancer. ONCOTARGET[J]. 2015, 第 12 作者6(25): 21730-21739, https://www.webofscience.com/wos/woscc/full-record/WOS:000360969200080.
[91] Li, Jie, Fang, Jianping, Qin, Yi, Liao, Wenfeng, Liu, Hailing, Zhou, Yifa, Ding, Kan. GLCE regulates PC12 cell neuritogenesis induced by nerve growth factor through activating SMAD/ID3 signalling. BIOCHEMICAL JOURNAL[J]. 2014, 第 7 作者459: 405-415, https://www.webofscience.com/wos/woscc/full-record/WOS:000334325400015.
[92] Zhang, Lei, Wang, Peipei, Ding, Kan. The mechanism underlying anti-cancer bioactivity of glycan. GLYCOBIOLOGY. 2014, 第 3 作者24(11): 1185-1185, https://www.webofscience.com/wos/woscc/full-record/WOS:000344670300279.
[93] Wang, Peipei, Ding, Kan. Proteoglycans and Glycosaminoglycans in Misfolded Proteins Formation in Alzheimer's Disease. PROTEIN AND PEPTIDE LETTERS[J]. 2014, 第 2 作者  通讯作者  21(10): 1048-1056, https://www.webofscience.com/wos/woscc/full-record/WOS:000341871000011.
[94] Qin, Yi, Li, Jie, Xu, Eric, Ding, Kan. Structure and catalytic mechanism of D-glucuronyl C5 epimerase, and the role in neuritogenesis regulation in PC12 cell. FASEB JOURNAL. 2014, 第 4 作者28(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000346646704280.
[95] 陈城, 方建平, 王滢, 王海颖, 丁侃. 硫酸化支链淀粉抑制rankl诱导破骨细胞的形成及其作用机制. 中国新药杂志[J]. 2014, 第 5 作者23(1): 25, 
[96] Wang, Ying, Shen, Xiaokun, Liao, Wenfeng, Fang, Jianping, Chen, Xia, Dong, Qun, Ding, Kan. A heteropolysaccharide, L-fuco-D-manno-1,6-alpha-D-galactan extracted from Grifola frondosa and antiangiogenic activity of its sulfated derivative. CARBOHYDRATE POLYMERS[J]. 2014, 第 7 作者  通讯作者  101: 631-641, http://dx.doi.org/10.1016/j.carbpol.2013.09.085.
[97] Wang, Peipei, Liao, Wenfeng, Fang, Jianping, Liu, Qin, Yao, Jian, Hu, Minghua, Ding, Kan. A glucan isolated from flowers of Lonicera japonica Thunb. inhibits aggregation and neurotoxicity of A beta(42). CARBOHYDRATEPOLYMERS[J]. 2014, 第 7 作者  通讯作者  110: 142-147, http://dx.doi.org/10.1016/j.carbpol.2014.03.060.
[98] Ying Wang, Xiaokun Shen, Wenfeng Liao, Jianping Fang, Xia Chen, Qun Dong, Kan Ding. A heteropolysaccharide, l-fuco-d-manno-1,6-α-d-galactan extracted from Grifola frondosa and antiangiogenic activity of its sulfated derivative. CARBOHYDRATE POLYMERS. 2014, 第 7 作者101: 631-641, http://dx.doi.org/10.1016/j.carbpol.2013.09.085.
[99] Shi, Lei, Dong, Qun, Ding, Kan. Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata. FOOD CHEMISTRY[J]. 2014, 第 3 作者152: 291-296, http://dx.doi.org/10.1016/j.foodchem.2013.11.091.
[100] Cong, Qifei, Shang, Mingsheng, Dong, Qun, Liao, Wenfeng, Xiao, Fei, Ding, Kan. Structure and activities of a novel heteroxylan from Cassia obtusifolia seeds and its sulfated derivative. CARBOHYDRATERESEARCH[J]. 2014, 第 6 作者393: 43-50, http://dx.doi.org/10.1016/j.carres.2014.04.016.
[101] Kan Ding. Proteoglycans and Glycosaminoglycans in Misfolded Proteins Formation in Alzheimer’s Disease. Protein Pept Lett. Protein Pept Lett. 2014, 第 1 作者  通讯作者  
[102] Peipei Wang, Wenfeng Liao, Jianping Fang, Qin Liu, Jian Yao, Minghua Hu, Kan Ding. A glucan isolated from flowers of Lonicera japonica Thunb. inhibits aggregation and neurotoxicity of Aβ42. CARBOHYDRATE POLYMERS. 2014, 第 7 作者110: 142-147, http://dx.doi.org/10.1016/j.carbpol.2014.03.060.
[103] Kan Ding. Glce regulates PC12 cell neuritogenesis induced by nerve growth factor through activating Smad/Id3 signaling. Biochem J. 2014, 第 1 作者  通讯作者  
[104] Cong, Qifei, Xiao, Fei, Liao, Wenfeng, Dong, Qun, Ding, Kan. Structure and biological activities of an alginate from Sargassum fusiforme, and its sulfated derivative. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2014, 第 5 作者69: 252-259, http://dx.doi.org/10.1016/j.ijbiomac.2014.05.056.
[105] Liu, Hailing, Zhou, Ling, Shi, Songshan, Wang, Ying, Ni, Xinyan, Xiao, Fei, Wang, Shunchun, Li, Ping, Ding, Kan. Oligosaccharide G19 inhibits U-87 MG human glioma cells growth in vitro and in vivo by targeting epidermal growth factor (EGF) and activating p53/p21 signaling. GLYCOBIOLOGY[J]. 2014, 第 9 作者  通讯作者  24(8): https://www.webofscience.com/wos/woscc/full-record/WOS:000339418000008.
[106] 张晓曼, 廖文锋, 丛启飞, 董群, 丁侃. 桑白皮水提取多糖组分的分离纯化和结构特征. 化学学报[J]. 2013, 第 5 作者71(5): 722-728, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFD2013&filename=HXXB201305004&v=MjExMDkrWm1GeXZtVzd2SkxUWFRiTEc0SDlMTXFvOUZZSVI4ZVgxTHV4WVM3RGgxVDNxVHJXTTFGckNVUjdxZmI=.
[107] Zhang Xiaoman, Liao Wenfeng, Cong Qifei, Dong Qun, Ding Kan. Isolation and Structural Characterization of the Polysaccharides of Cortex Mori radices. ACTA CHIMICA SINICA[J]. 2013, 第 5 作者71(5): 722-728, http://dx.doi.org/10.6023/A13010109.
[108] 王恒禹, 刘玥, 姜猛, 丁侃. 多糖在食品工业中的应用现状. 食品科学[J]. 2013, 第 4 作者34(21): 431, http://lib.cqvip.com/Qikan/Article/Detail?id=47715801.
[109] 黄雄超, 刘玥, 姜猛, 丁侃. 我国保健食品的发展现状与前景. 中国保健营养:下半月[J]. 2013, 第 4 作者492-493, http://lib.cqvip.com/Qikan/Article/Detail?id=90726674504849514850535556.
[110] 范灵婧, 倪鑫炎, 吴纯洁, 丁侃. 菊花多糖的结构特征及其对nfb和肿瘤细胞的活性研究. 中草药[J]. 2013, 第 4 作者44(17): 2364, http://lib.cqvip.com/Qikan/Article/Detail?id=47290578.
[111] Xiao, Fei, Qiu, Hong, Zhou, Ling, Shen, Xiaokun, Yang, Liping, Ding, Kan. WSS25 inhibits Dicer, downregulating microRNA-210, which targets Ephrin-A3, to suppress human microvascular endothelial cell (HMEC-1) tube formation. GLYCOBIOLOGY[J]. 2013, 第 6 作者23(5): 524-535, https://www.webofscience.com/wos/woscc/full-record/WOS:000316964600003.
[112] Liu, HanWei, Yu, XiuZhu, Padula, Daniele, Pescitelli, Gennaro, Lin, ZhiWei, Wang, Fei, Ding, Kai, Lei, Ming, Gao, JinMing. Lignans from Schisandra sphenathera Rehd. et Wils. and semisynthetic schisantherin A analogues: Absolute configuration, and their estrogenic and anti-proliferative activity. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY[J]. 2013, 59: 265-273, http://dx.doi.org/10.1016/j.ejmech.2012.11.003.
[113] Wang, Ying, Fang, Jianping, Ni, Xinyan, Li, Jie, Liu, Qin, Dong, Qun, Duan, Jinyou, Ding, Kan. Inducement of Cytokine Release by GFPBW2, a Novel Polysaccharide from Fruit Bodies of Grifola frondosa, through Dectin-1 in Macrophages. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2013, 第 8 作者61(47): 11400-11409, https://www.webofscience.com/wos/woscc/full-record/WOS:000327812500020.
[114] Zhang Xiaoman, Liao Wenfeng, Cong Qifei, Dong Qun, Ding Kan. Isolation and Structural Characterization of the Polysaccharides of Cortex Mori radices. ACTA CHIMICA SINICA[J]. 2013, 第 5 作者71(5): 722-728, https://www.webofscience.com/wos/woscc/full-record/WOS:000320011200005.
[115] Lv, Xiaofen, Chen, Sihan, Li, Jie, Fang, Jianping, Guo, Yuewei, Ding, Kan. Lobolide, a diterpene, blockades the NF-kappa B pathway and p38 and ERK MAPK activity in macrophages in vitro. ACTA PHARMACOLOGICA SINICA[J]. 2012, 第 6 作者33(10): 1293-1300, http://dx.doi.org/10.1038/aps.2012.100.
[116] Jian-ping FANG, Yang LIU, Jie LI, Wen-feng LIAO, You-hong HU, Kan DING. A novel small molecule, HK-156, inhibits lipopoly- saccharide-induced activation of NF-KB signaling and improves survival in mouse models of sepsis. 中国药理学报:英文版[J]. 2012, 第 6 作者33(9): 1204-1216, http://lib.cqvip.com/Qikan/Article/Detail?id=43191429.
[117] Lv Xiaofen, Chen Sihan, Li Jie, Fang Jianping, Guo Yuewei, Ding Kan. lobolideaditerpeneblockadesthenfbpathwayandp38anderkmapkactivityinmacrophagesinvitro. ACTAPHARMACOLOGICASINICA[J]. 2012, 第 6 作者33(10): 1293, http://lib.cqvip.com/Qikan/Article/Detail?id=43458973.
[118] Fang, Jianping, Wang, Ying, Lv, Xiaofen, Shen, Xiaokun, Ni, Xinyan, Ding, Kan. Structure of a beta-glucan from Grifola frondosa and its antitumor effect by activating Dectin-1/Syk/NF-kappa B signaling. GLYCOCONJUGATE JOURNAL[J]. 2012, 第 6 作者  通讯作者  29(5-6): 365-377, https://www.webofscience.com/wos/woscc/full-record/WOS:000307763900014.
[119] Fang, Jianping, Liu, Yang, Li, Jie, Liao, Wenfeng, Hu, Youhong, Ding, Kan. A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-kappa B signaling and improves survival in mouse models of sepsis. ACTA PHARMACOLOGICA SINICA[J]. 2012, 第 6 作者33(9): 1204-1216, https://www.webofscience.com/wos/woscc/full-record/WOS:000308391000013.
[120] Dong, Qun, Wang, Ying, Shi, Lei, Yao, Jian, Li, Jie, Ma, Fangli, Ding, Kan. A novel water-soluble beta-D-glucan isolated from the spores of Ganoderma lucidum. CARBOHYDRATE RESEARCH[J]. 2012, 第 7 作者353: 100-105, https://www.webofscience.com/wos/woscc/full-record/WOS:000304053900014.
[121] Cao, Bin, Wang, Yong, Ding, Kan, Neamati, Nouri, Long, YaQiu. Synthesis of the pyridinyl analogues of dibenzylideneacetone (pyr-dba) via an improved Claisen-Schmidt condensation, displaying diverse biological activities as curcumin analogues. ORGANIC & BIOMOLECULAR CHEMISTRY[J]. 2012, 第 3 作者10(6): 1239-1245, https://www.webofscience.com/wos/woscc/full-record/WOS:000299342200015.
[122] Kan Ding. Structure of a β-glucan from Grifola frondosa and its antitumor effect by activating Dectin-1/Syk/NF-κB signaling. Glycoconj J. 2012, 第 1 作者  通讯作者  
[123] Qun Dong, Ying Wang, Lei Shi, Jian Yao, Jie Li, Fangli Ma, Kan Ding. A novel water-soluble β-d-glucan isolated from the spores of Ganoderma lucidum. CARBOHYDRATE RESEARCH. 2012, 第 7 作者353: 100-105, http://dx.doi.org/10.1016/j.carres.2012.02.029.
[124] Liu, Yang, Fang, Jianping, Cai, Haiyan, Xiao, Fei, Ding, Kan, Hu, Youhong. Identification and synthesis of substituted pyrrolo2,3-dpyrimidines as novel firefly luciferase inhibitors. BIOORGANIC & MEDICINAL CHEMISTRY[J]. 2012, 第 5 作者  通讯作者  20(18): 5473-5482, http://dx.doi.org/10.1016/j.bmc.2012.07.035.
[125] Feng, Chao, Li, Jie, Ruan, Jinlan, Ding, Kan. MicroRNA-125a inhibits cell growth by targeting glypican-4. GLYCOCONJUGATE JOURNAL[J]. 2012, 第 4 作者  通讯作者  29(7): 503-511, https://www.webofscience.com/wos/woscc/full-record/WOS:000308356000005.
[126] Fang Jianping, Liu Yang, Li Jie, Liao Wenfeng, Hu Youhong, Ding Kan. A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-κB signaling and improves survival in mouse models of sepsis. ACTA PHARMACOLOGICA SINICA[J]. 2012, 第 6 作者33(9): 1204,  http://dx.doi.org/10.1038/aps.2012.56.
[127] Yu, Qianming, Yan, Jun, Wang, Shunchun, Ji, Lili, Ding, Kan, Vella, Cherelyn, Wang, Zhengtao, Hu, Zhibi. Antiangiogenic effects of GFP08, an agaran-type polysaccharide isolated from Grateloupia filicina. GLYCOBIOLOGY[J]. 2012, 第 5 作者22(10): 1343-1352, http://www.corc.org.cn/handle/1471x/2298991.
[128] Chen, Xia, Xiao, Fei, Wang, Ying, Fang, Jianping, Ding, Kan. Structure-activity relationship study of WSS25 derivatives with anti-angiogenesis effects. GLYCOCONJUGATE JOURNAL[J]. 2012, 第 5 作者29(5-6): 389-398, https://www.webofscience.com/wos/woscc/full-record/WOS:000307763900016.
[129] Shang, Mingsheng, Zhang, Xiaoman, Dong, Qun, Yao, Jian, Liu, Qin, Ding, Kan. Isolation and structural characterization of the water-extractable polysaccharides from Cassia obtusifolia seeds. CARBOHYDRATE POLYMERS[J]. 2012, 第 6 作者90(2): 827-832, http://dx.doi.org/10.1016/j.carbpol.2012.06.007.
[130] Xiao-fen LV, Si-han CHEN, Jie LI, Jian-ping FANG, Yue-wei GUO, Kan DING. Lobolide, a diterpene, blockades the NF-κB pathway and p38 and ERK MAPK activity in macrophages in vitro. 中国药理学报:英文版[J]. 2012, 第 6 作者33(10): 1293, http://lib.cqvip.com/Qikan/Article/Detail?id=43458973.
[131] Shen, Xiaokun, Fang, Jianping, Lv, Xiaofen, Pei, Zhicao, Wang, Ying, Jiang, Songshan, Ding, Kan. Heparin Impairs Angiogenesis through Inhibition of MicroRNA-10b. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2011, 第 7 作者286(30): 26616-26627, http://dx.doi.org/10.1074/jbc.M111.224212.
[132] Song, Kai, Li, Qin, Peng, YongBo, Li, Jie, Ding, Kan, Chen, LiJuan, Shao, ChengHao, Zhang, LiJun, Li, Ping. Silencing of hHS6ST2 inhibits progression of pancreatic cancer through linhibition of Notch signalling. BIOCHEMICAL JOURNAL[J]. 2011, 第 5 作者436: 271-282, https://www.webofscience.com/wos/woscc/full-record/WOS:000291413200008.
[133] 周玲, 白志川, 丁侃. 蜈蚣藻的活性成分及其理活性研究进展. 中药材[J]. 2011, 第 3 作者34(1): 147-150, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=4154535&detailType=1.
[134] 邱宏, 丁侃. 硫酸乙酰肝素蛋白聚糖的功能机制研究进展. 生命科学[J]. 2011, 第 2 作者23(7): 648, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFD2011&filename=SMKX201107007&v=MDIzNjlEaDFUM3FUcldNMUZyQ1VSN3FmYitabUZ5emxXcjNLTmlEQWRyRzRIOURNcUk5Rlk0UjhlWDFMdXhZUzc=.
[135] 周玲, 白志川, 丁侃. 蜈蚣藻的活性成分及其药理活性研究进展. 中药材[J]. 2011, 第 3 作者34(1): 147-150, http://lib.cqvip.com/Qikan/Article/Detail?id=36891378.
[136] 刘芹, 宁嘉玲, 丁侃. 基于高效凝胶渗透色谱法的银耳多糖质量控制研究. 中草药[J]. 2011, 第 3 作者42(9): 1732, http://lib.cqvip.com/Qikan/Article/Detail?id=39218271.
[137] Cui, Hengxiang, Shao, Chenghao, Liu, Qin, Yu, Wenjie, Fang, Jianping, Yu, Weishi, Ali, Amjad, Ding, Kan. Heparanase enhances nerve-growth-factor-induced PC12 cell neuritogenesis via the p38 MAPK pathway. BIOCHEMICAL JOURNAL[J]. 2011, 第 8 作者  通讯作者  440: 273-282, https://www.webofscience.com/wos/woscc/full-record/WOS:000298222200011.
[138] Chen, Xia, Cao, Dianxiu, Zhou, Ling, Jin, Hongying, Dong, Qun, Yao, Jian, Ding, Kan. Structure of a polysaccharide from Gastrodia elata Bl., and oligosaccharides prepared thereof with anti-pancreatic cancer cell growth activities. CARBOHYDRATE POLYMERS[J]. 2011, 第 7 作者  通讯作者  86(3): 1300-1305, http://dx.doi.org/10.1016/j.carbpol.2011.06.029.
[139] Wu, GuangWei, Gao, JinMing, Shi, XinWei, Zhang, Qiang, Wei, ShaoPeng, Ding, Kan. Microbial Transformations of Diosgenin by the White-Rot Basidiomycete Coriolus versicolor. JOURNAL OF NATURAL PRODUCTS[J]. 2011, 第 6 作者74(10): 2095-2101, https://www.webofscience.com/wos/woscc/full-record/WOS:000296206500009.
[140] Xu, Yuxia, Dong, Qun, Qiu, Hong, Ma, ChungWah, Ding, Kan. A homogalacturonan from the radix of Platycodon grandiflorum and the anti-angiogenesis activity of poly-/oligogalacturonic acids derived therefrom. CARBOHYDRATE RESEARCH[J]. 2011, 第 5 作者346(13): 1930-1936, http://dx.doi.org/10.1016/j.carres.2011.05.011.
[141] Kan Ding. Silencing of hHS6ST2 inhibits progression of pancreatic cancer through inhibition of Notch signaling. Biochem J. 2011, 第 1 作者  通讯作者  
[142] 章漳, 段朝辉, 丁侃, 王峥涛. 长梗秦艽酮体外抗肿瘤活性及其作用机制探讨. 中国药学杂志[J]. 2010, 第 3 作者259, http://lib.cqvip.com/Qikan/Article/Detail?id=32962864.
[143] Fei Xiao, Kan Ding. Microrna-93 Targeting Heparan Sulfate Biosynthesis Enzyme HS2ST1 Enhances Tumor Cell Growth and HMEC-1 Cell Tube Formation. GLYCOBIOLOGY. 2010, 第 2 作者20(11): 1503-1503, https://www.webofscience.com/wos/woscc/full-record/WOS:000282750300177.
[144] Ding, Kan, Shen, Xiaokun, Xiao, Fei. Microrna Function Study Implicated in Cell Growth and Angiogenesis Probed by Heparan Sulfate Mimetic. GLYCOBIOLOGY. 2010, 第 1 作者20(11): 1482-1482, https://www.webofscience.com/wos/woscc/full-record/WOS:000282750300114.
[145] Tong, Xiankun, Qiu, Hong, Zhang, Xin, Shi, Liping, Wang, Guifeng, Ji, Feihong, Ding, Huiyong, Tang, Wei, Ding, Kan, Zuo, Jianping. WSS45, a sulfated alpha-D-glucan, strongly interferes with Dengue 2 virus infection in vitro. ACTA PHARMACOLOGICA SINICA[J]. 2010, 第 9 作者31(5): 585-592, http://dx.doi.org/10.1038/aps.2010.29.
[146] Dong, Qun, Liu, Xuan, Yao, Jian, Dong, Xiaotang, Ma, Chao, Xu, Yuxia, Fang, Jinian, Ding, Kan. Structural characterization of a pectic polysaccharide from Nerium indicum flowers. PHYTOCHEMISTRY[J]. 2010, 第 8 作者  通讯作者  71(11-12): 1430-1437, http://dx.doi.org/10.1016/j.phytochem.2010.05.019.
[147] Duan, Jinyou, Chen, Vincent L, Dong, Qun, Ding, Kan, Fang, Jinian. Chemical structure and immunoinhibitory activity of a pectic polysaccharide containing glucuronic acid from the leaves of Diospyros kaki. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2010, 第 4 作者46(5): 465-470, http://dx.doi.org/10.1016/j.ijbiomac.2010.03.014.
[148] Xu, Yuxia, Dong, Qun, Qiu, Hong, Cong, Renhuai, Ding, Kan. Structural Characterization of an Arabinogalactan from Platycodon grandiflorum Roots and Antiangiogenic Activity of Its Sulfated Derivative. BIOMACROMOLECULES[J]. 2010, 第 5 作者11(10): 2558-2566, http://ir.simm.ac.cn/handle/153631/1958.
[149] Duan, Jinyou, Dong, Qun, Ding, Kan, Fang, Jinian. Characterization of a Pectic Polysaccharide from the Leaves of Diospyros kaki and Its Modulating Activity on Lymphocyte Proliferation. BIOPOLYMERS[J]. 2010, 第 3 作者93(7): 649-656, http://ir.simm.ac.cn/handle/153631/2020.
[150] Kan Ding. A Polysaccharides, MDG-1, induces S1P1 and bFGF expression and augments survival and angiogenesis in the ischemic heart. Glycobiology. 2010, 第 1 作者  通讯作者  
[151] Qiu, Hong, Yang, Bo, Pei, ZhiChao, Zhang, Zhang, Ding, Kan. WSS25 Inhibits Growth of Xenografted Hepatocellular Cancer Cells in Nude Mice by Disrupting Angiogenesis via Blocking Bone Morphogenetic Protein (BMP)/Smad/Id1 Signaling. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2010, 第 5 作者  通讯作者  285(42): 32638-32646, http://dx.doi.org/10.1074/jbc.M110.105544.
[152] Ma, Zhaocheng, Wang, Jianguo, Zhang, Lina, Zhang, Yufeng, Ding, Kan. Evaluation of water soluble beta-D-glucan from Auricularia auricular-judae as potential anti-tumor agent. CARBOHYDRATE POLYMERS[J]. 2010, 第 5 作者80(3): 977-983, http://ir.simm.ac.cn/handle/153631/2057.
[153] Kan Ding. WSS45, a sulfated α-D-glucan compound, strongly interfere with Dengue 2 virus infection in vitro. Acta Pharmacologica Sinica. 2010, 第 1 作者  通讯作者  
[154] 王硕, 冯怡, 丁侃, 王新平, 徐德生. 麦冬多糖通过S1P1通路保护OGD条件下细胞生存. 药物生物技术[J]. 2009, 第 3 作者220, http://lib.cqvip.com/Qikan/Article/Detail?id=30808253.
[155] 陶咏真, 张俐娜, 韩露, 曾凡波, 丁侃. 水溶性高支化多糖及硫酸酯衍生物抗癌活性研究. 高分子学报[J]. 2009, 第 5 作者852-859, http://lib.cqvip.com/Qikan/Article/Detail?id=31549319.
[156] 章漳, 段朝辉, 丁侃, 王峥涛. 长梗秦艽酮通过调节Akt和ERK1/2通路抑制人肝癌BEL-7402细胞生长. 中国中药杂志[J]. 2009, 第 3 作者3277-3280, http://lib.cqvip.com/Qikan/Article/Detail?id=1001310270.
[157] Tao Yongzhen, Zhang Lina, Han Lu, Zeng Fanbo, Ding Kan. STUDIES ON ANTITUMOR ACTIVITY OF A WATER-SOLUBLE HYPERBRANCHED POLYSACCRARIDE AND ITS SULFATED DERIVATIVES. ACTA POLYMERICA SINICA[J]. 2009, 第 5 作者852-859, http://ir.simm.ac.cn/handle/153631/1082.
[158] 章漳, 王硕, 邱宏, 王峥涛, 丁侃. 硫酸乙酰肝素蛋白聚糖与病毒感染. 中国医疗前沿[J]. 2009, 第 5 作者1-3, http://lib.cqvip.com/Qikan/Article/Detail?id=29795732.
[159] 王硕, 冯怡, 徐德生, 章漳, 丁侃. 麦冬多糖MDG-1对内皮细胞瘦素表达的影响. 中国应用生理学杂志[J]. 2009, 第 5 作者160, http://lib.cqvip.com/Qikan/Article/Detail?id=30467132.
[160] 陈霞, 刘芹, 丁侃. 松茸的化学成分、活性及其药理作用研究进展. 中国医疗前沿[J]. 2009, 第 3 作者114-116, http://lib.cqvip.com/Qikan/Article/Detail?id=30990010.
[161] Kan Ding. Study on antitumor activity of a water-soluble hyperbranched polysaccharide and its sulfated derivatives. ACTAPOLYMERICASINIC. 2009, 第 1 作者  通讯作者  
[162] Hu, Ke, Liu, Qin, Wang, Shunchun, Ding, Kan. New oligosaccharides prepared by acid hydrolysis of the polysaccharides from Nerium indicum Mill and their anti-angiogenesis activities. CARBOHYDRATE RESEARCH[J]. 2009, 第 4 作者344(2): 198-203, http://dx.doi.org/10.1016/j.carres.2008.10.019.
[163] Zhang, Zhang, Wang, Shuo, Qiu, Hong, Duan, Chaohui, Ding, Kan, Wang, Zhengtao. Waltonitone induces human hepatocellular carcinoma cells apoptosis in vitro and in vivo. CANCER LETTERS[J]. 2009, 第 5 作者  通讯作者  286(2): 223-231, http://dx.doi.org/10.1016/j.canlet.2009.05.023.
[164] Cui, Hengxiang, Liu, Qin, Tao, Yongzhen, Zhang, Hongfeng, Zhang, Lina, Ding, Kan. Structure and chain conformation of a (1 -> 6)-alpha-D-glucan from the root of Pueraria lobata (Willd.) Ohwi and the antioxidant activity of its sulfated derivative. CARBOHYDRATE POLYMERS[J]. 2008, 第 6 作者  通讯作者  74(4): 771-778, https://www.webofscience.com/wos/woscc/full-record/WOS:000259765300003.
[165] Qiu, Hong, Ding, Kan. Sulfated Polysaccharide KD1 Inhibits Angiogenesis via Down-regulating Id1 Expression. GLYCOBIOLOGY. 2008, 第 2 作者18(11): 954-954, https://www.webofscience.com/wos/woscc/full-record/WOS:000260141400069.
[166] 董群, 丁侃. 多糖类药物分析中的含量测定方法及研究进展. 2008, 第 2 作者46, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CPFD&dbname=CPFD9908&filename=YYWS200807001014&v=MDQ1OTV2SGludFU3bkpKRnNTUERUY2ZiRzRIdG5NcUk5Rlplc09DQk5LdWhkaG5qOThUbmpxcXhkRWVNT1VLcmlmWmVa.
[167] 崔恒祥, 刘芹, 陶永真, 张俐娜, 丁侃. 葛根中(1→6)-α-D-葡聚糖的结构,构象及其硫酸化衍生物抗氧化活性. 2008, 第 5 作者195-205, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CPFD&dbname=CPFD9908&filename=YYWS200807001057&v=MjM5MTNNT1VLcmlmWmVadkhpbnRVN25KSjE4Y1BEVGNmYkc0SHRuTXFJOUZaZXNLQ3hOS3VoZGhuajk4VG5qcXF4ZEVl.
[168] 雷丰丰, 赵健雄, 王学习, 姚宝泰, 丁侃. 红芪总多糖诱导s180瘤细胞凋亡的实验研究. 中成药[J]. 2008, 第 5 作者30(7): 961, http://lib.cqvip.com/Qikan/Article/Detail?id=27859242.
[169] Kan Ding. Structure and chain conformation of a (1→6)-a-D-glucan from the root of Puerarialobata (Willd.) Ohwi and the antioxidant activity of its sulfated derivative. Carbohydr Polym. 2008, 第 1 作者  通讯作者  
[170] Liu, Liu, Dong, Qun, Dong, Xiaotang, Fang, Jinian, Ding, Kan. Structural investigation of two neutral polysaccharides isolated from rhizome of Polygonatum sibiricum. CARBOHYDRATE POLYMERS[J]. 2007, 第 5 作者  通讯作者  70(3): 304-309, http://dx.doi.org/10.1016/j.carbpol.2007.04.012.
[171] 方积年, 丁侃. 天然药物——多糖的主要生物活性及分离纯化方法. 中国天然药物[J]. 2007, 第 2 作者5(5): 338-347, http://lib.cqvip.com/Qikan/Article/Detail?id=25516321.
[172] 雷丰丰, 赵健雄, 王学习, 姚宝泰, 丁侃. 红芪总多糖对小鼠S180瘤的抑制作用及其机制研究. 中药材[J]. 2007, 第 5 作者30(12): 1548, http://lib.cqvip.com/Qikan/Article/Detail?id=26305731.
[173] 王赛贞, 丁侃, 林树钱, 林志彬. 赤芝多糖肽GL-PP-3A的分离纯化和结构研究. 药学学报[J]. 2007, 第 2 作者42(10): 1058, http://lib.cqvip.com/Qikan/Article/Detail?id=25827586.
[174] Dong, Qun, Yao, Han, Fang, Jinian, Ding, Kan. Structural characterization and immunological activity of two cold-water extractable polysaccharides from Cistanche deserticola Y. C. Ma. CARBOHYDRATE RESEARCH[J]. 2007, 第 4 作者  通讯作者  342(10): 1343-1349, http://dx.doi.org/10.1016/j.carres.2007.03.017.
[175] Blondeau, Nicolas, Lai, Yushuan, Tyndall, Sarah, Popolo, Margherita, Topalkara, Kamil, Pru, James K, Zhang, Ling, Kim, HyungHwan, Liao, James K, Ding, Kan, Waeber, Christian. Distribution of sphingosine kinase activity and mRNA in rodent brain. JOURNAL OF NEUROCHEMISTRY[J]. 2007, 第 10 作者103(2): 509-517, https://www.webofscience.com/wos/woscc/full-record/WOS:000250384500008.
[176] Kan Ding. Separation, Purification and Structure Characterization of a Polysaccharide from Roots of Cudrania tricuspidata(Carr.). Bur. Chem. J. Chin. Univ.-Chin. 2007, 第 1 作者  通讯作者  
[177] Kan Ding. Structure elucidation and sulfated derivatives preparation of two alpha-glycan from Gstrodia elata Bl. and their anti-dengue virus bioactivities. Carbohydr Res. 2007, 第 1 作者  通讯作者  
[178] Kan Ding. Structure investigation of two neutral polysaccharides isolated from rhizome of Polygonatum sibiricum. Carbohydr Polym. 2007, 第 1 作者  通讯作者  
[179] Kan Ding. Monodispersed Fe-Pt Nanoparticles for Biomedical Application. J. Appl. Phys. 2005, 第 1 作者
[180] Ding, K, LopezBurks, M, SanchezDuran, JA, Korc, M, Lander, AD. Growth factor-induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells. JOURNAL OF CELL BIOLOGY[J]. 2005, 171(4): 729-738, 
[181] Kan Ding. Fransson LA The heparan sulfate-specific epitope 10E4 is NO-sensitive and partly inaccessible in glypican-1. Glycobiology. 2004, 第 1 作者  通讯作者  
[182] Kan Ding. Characterization of a rhamnogalacturonan and xyloglycan from Nerium indicum and their activities on PC12 pheochromocytoma cells. J Nat Prod. 2003, 第 1 作者
[183] Ding, K, Mani, K, Cheng, F, Belting, M, Fransson, LA. Copper-dependent autocleavage of glypican-1 heparan sulfate by nitric oxide derived from intrinsic nitrosothiols. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2002, 277(36): 33353-33360, http://dx.doi.org/10.1074/jbc.M203383200.
[184] Cheng, F, Mani, K, van den Born, J, Ding, K, Belting, M, Fransson, LA. Nitric oxide-dependent processing of heparan sulfate in recycling S-nitrosylated glypican-1 takes place in caveolin-1-containing endosomes. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2002, 277(46): 44431-44439, https://www.webofscience.com/wos/woscc/full-record/WOS:000179272000114.
[185] Ding, K, Sandgren, S, Mani, K, Belting, M, Fransson, LA. Modulations of glypican-1 heparan sulfate structure by inhibition of endogenous polyamine synthesis - Mapping of spermine-binding sites and heparanase, heparin lyase, and nitric oxide/nitrite cleavage sites. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2001, 276(50): 46779-46791, http://dx.doi.org/10.1074/jbc.M105419200.
[186] Ding, K, Jonsson, M, Mani, K, Sandgren, S, Belting, M, Fransson, LA. N-unsubstituted glucosamine in heparan sulfate of recycling glypican-1 from suramin-treated and nitrite-deprived endothelial cells - Mapping of nitric oxide/nitrite-susceptible glucosamine residues to clustered sites near the: Core protein. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2001, 276(6): 3885-3894, http://dx.doi.org/10.1074/jbc.M005238200.
[187] 丁侃, 方积年. 多糖类药物的毛细管电泳分析方法及其应用. 色谱[J]. 1999, 第 1 作者17(4): 3-5, http://lib.cqvip.com/Qikan/Article/Detail?id=3722440.
[188] 丁侃, 方积年. 中药走向世界的障碍剖析与思路. 中草药[J]. 1998, 第 1 作者29(8): 3-5, http://lib.cqvip.com/Qikan/Article/Detail?id=3115545.
[189] Ding, K, Lin, G, Ho, YP, Cheng, TY, Li, P. Prederivatization and high-performance liquid chromatographic analysis of alkaloids of bulbs of Fritillaria. JOURNAL OF PHARMACEUTICAL SCIENCES[J]. 1996, 85(11): 1174-1179, http://dx.doi.org/10.1021/js960211v.
[190] Fei He, Haowen Jiang, Chang Peng, Tingting Wang, Rongrong Xiao, Meilin Chen, Nixue Song, Zhenyun Du, Hanlin Wang, Xiaoyu Ding, Yikai Shao, Jianping Fang, Yi Zang, Rong Hua, Jia Li, Kan Ding. Hepatic glucuronyl C5-epimerase combats obesity by stabilizing GDF15. JOURNAL OF HEPATOLOGY. 第 16 作者http://dx.doi.org/10.1016/j.jhep.2023.05.011.
[191] Shen Xiaokun, Fang Jianping, Lv Xiaofen, Pei Zhicao, Wang Ying, Jiang Songshan, Ding Kan. Heparin Impairs Angiogenesis through Inhibition of MicroRNA-10b *. THE JOURNAL OF BIOLOGICAL CHEMISTRY. 第 7 作者286(30): 26616-26627, http://dx.doi.org/10.1074/jbc.M111.224212.

指导学生

已指导学生

方建平  博士研究生  100720-药物设计学  

吕晓芬  博士研究生  100701-药物化学  

邱宏  博士研究生  100701-药物化学  

陈霞  硕士研究生  077901-药物化学  

沈孝坤  博士研究生  100706-药理学  

现指导学生

廖文锋  硕士研究生  077906-药理学  

王滢  博士研究生  100701-药物化学  

秦毅  硕士研究生  077906-药理学  

肖斐  博士研究生  100706-药理学  

王武成  硕士研究生  077901-药物化学