丁宝全 男 博导 国家纳米科学中心
电子邮件: dingbq@nanoctr.cn
通信地址: 国家纳米科学中心
邮政编码: 100190
电子邮件: dingbq@nanoctr.cn
通信地址: 国家纳米科学中心
邮政编码: 100190
研究领域
生物纳米材料与器件
招生信息
招生专业
070304-物理化学(含:化学物理)071011-生物物理学0703J1-纳米科学与技术
招生方向
生物纳米材料自组装与微纳加工结合技术纳米电子光子学
教育背景
2000-09--2006-08 纽约大学 博士学位1996-09--2000-07 吉林大学 学士学位
工作经历
2009-10--2010-10 亚利桑那州立大学 研究助理教授
2006-09--2009-09 劳伦斯伯克利国家实验室 博士后
2006-09--2009-09 劳伦斯伯克利国家实验室 博士后
教授课程
纳米功能材料
专利与奖励
专利成果
( 1 ) Polygonal nanostructures of polynucleic acid multi-crossover molecules and assembly of lattices based on double crossover cohesion, 发明, 2006, 第 2 作者, 专利号: U.S. Pat. Appl. Publ. (2006), 55 pp( 2 ) 一种用于运载抗肿瘤药物的核酸纳米结构及其制备方法和应用, 发明, 2013, 第 1 作者, 专利号: 201310351835.7( 3 ) 一种金钯双金属卫星结构组装体及其制备方法和应用, 发明, 2013, 第 1 作者, 专利号: 201310351835.7( 4 ) 一种海参状核壳结构金银纳米复合材料, 发明, 2015, 第 1 作者, 专利号: 201510172371.2( 5 ) 一种用于活体光声成像的核酸纳米结构-贵金属光敏造影剂复合物探针及其制备方法和应用, 发明, 2014, 第 1 作者, 专利号: 201410426106.8( 6 ) 装载凝血酶的DNA自组装纳米结构、其制备方法及应用, 发明, 2014, 第 3 作者, 专利号: 201410207351.X
出版信息
通讯作者发表论文
[1] Aqib, Raja Muhammad, Wang, Yuang, Liu, Jianbing, Ding, Baoquan. Efficient one-pot assembly of higher-order DNA nanostructures by chemically conjugated branched DNA. CHEMICAL COMMUNICATIONS[J]. 2024, 第 4 作者 通讯作者 60(35): 4715-4718, http://dx.doi.org/10.1039/d4cc01097c.[2] Hong Wang, Changping Yang, Tiantian Wu, Jing Fan, Hanyin Zhu, Jianbing Liu, Baoquan Ding. A Highly Tumor Permeating DNA Nanoplatform for Efficient Remodeling of Immunosuppressive Tumor Microenvironments. Angew. Chem. Int. Ed.[J]. 2024, 第 7 作者 通讯作者 null(null): 10.1002/anie.202412804, [3] Yiming Wang, Run Tian, Zhuoting Li, Shuaijing Ma, Yushuai Wu, Liu Fengsong, Qin Han, Jing Li, Robert Chunhua Zhao, Qiao Jiang, Baoquan Ding. Mesenchymal Stem Cells Engineered by Multicomponent Coassembled DNA Nanofibers for Enhanced Wound Healing. Nano Lett.[J]. 2024, 第 11 作者 通讯作者 24(null): 13955-13964, [4] Zhuoting Li, Yiming Wang, Hong Wang, Haiyan Wang, Yingxu Shang, Shihua Wang, Qin Han, Jing Li, Robert Chunhua Zhao, Qiao Jiang, Ding, Baoquan. Self-Assembled DNA Composite-Engineered Mesenchymal Stem Cells for Improved Skin-Wound Repair. Small[J]. 2024, 第 11 作者 通讯作者 20(null): 2310241, [5] Wang Yuang, Wang Hong, Li Yan, Yang Changping, Tang Yue, Lu Xuehe, Fan Jing, Tang Wantao, Shang Yingxu, Yan Hao, Liu Jianbing, Ding Baoquan. Chemically Conjugated Branched Staples for Super-DNA Origami. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2024, 第 12 作者 通讯作者 146(6): 4178-4186, [6] Haiyan Wang, Yunfei Jiao, Shuaijing Ma, Zhuoting Li, Jintao Gong, Qiao Jiang, Yingxu Shang, Hongling Li, Jing Li, Na Li, Robert Chunhua Zhao, Baoquan Ding. Nebulized Inhalation of Peptide-Modified DNA Origami To Alleviate Acute Lung Injury. Nano Letters[J]. 2024, 第 12 作者 通讯作者 24(null): 6102-6111, [7] Zhan, Pengfei, Peil, Andreas, Jiang, Qiao, Wang, Dongfang, Mousavi, Shikufa, Xiong, Qiancheng, Shen, Qi, Shang, Yingxu, Ding, Baoquan, Lin, Chenxiang, Ke, Yonggang, Liu, Na. Recent Advances in DNA Origami-Engineered Nanomaterials and Applications. CHEMICAL REVIEWS[J]. 2023, 第 9 作者 通讯作者 123(7): 3976-4050, http://dx.doi.org/10.1021/acs.chemrev.3c00028.[8] Pitikultham, Piyawat, Putnin, Thitirat, Pimalai, Dechnarong, Sathirapongsasuti, Nuankanya, Kitiyakara, Chagriya, Jiang, Qiao, Ding, Baoquan, Japrung, Deanpen. Ultrasensitive Detection of MicroRNA in Human Saliva via Rolling Circle Amplification Using a DNA-Decorated Graphene Oxide Sensor. ACS OMEGA[J]. 2023, 第 7 作者8(17): 15266-15275, http://dx.doi.org/10.1021/acsomega.3c00411.[9] Lu Xuehe, Wang Hong, Chen Ruofan, Wu Tiantian, Wu Xiaohui, Shang Yingxu, Wang Yuang, Tang Wantao, Liu Dongsheng, Liu Jianbing, Ding Baoquan. Long and Covalently Conjugated Branched DNA Structures for in Situ Gelation in Vivo. CCS CHEMISTRY[J]. 2023, 第 11 作者 通讯作者 5(9): 2125-2139, http://lib.cqvip.com/Qikan/Article/Detail?id=7110783632.[10] Li, Xianlei, Xu, Xuehui, Wang, Kewei, Chen, Yuqiu, Zhang, Yangyuchen, Si, Qingrui, Pan, Zian, Jia, Fan, Cui, Xinyue, Wang, Xuan, Deng, Xiongwei, Zhao, Yi, Shu, Dan, Jiang, Qiao, Ding, Baoquan, Wu, Yan, Liu, Ran. Fluorescence-Amplified Origami Microneedle Device for Quantitatively Monitoring Blood Glucose. ADVANCED MATERIALS[J]. 2023, 第 15 作者 通讯作者 35(29): http://dx.doi.org/10.1002/adma.202208820.[11] Wu, Fan, Li, Na, Ding, Baoquan, Zhang, Wei. Plasmon-Exciton Strong Coupling Effects of the Chiral Hybrid Nanostructures Based on the Plexcitonic Born-Kuhn Model. ACS PHOTONICS[J]. 2023, 第 3 作者 通讯作者 10(5): 1356-1366, http://dx.doi.org/10.1021/acsphotonics.2c02004.[12] Tang Wantao, Tong Ting, Wang Hong, Lu Xuehe, Yang Changping, Wu Yushuai, Wang Yuang, Liu Jianbing, Ding Baoquan. A DNA Origami-Based Gene Editing System for Efficient Gene Therapy in Vivo. Angewandte Chemie International Edition[J]. 2023, 第 9 作者 通讯作者 DOI:10.1002/anie.202315093: [13] Xianlei Li, Xuehui Xu, Kewei Wang, Yuqiu Chen, Yangyuchen Zhang, Qingrui Si, Zi'an Pan, Fan Jia, Xinyue Cui, Xuan Wang, Xiongwei Deng, Yi Zhao, Dan Shu, Qiao Jiang, Baoquan Ding, Yan Wu, Ran Liu. Fluorescence-Amplified Origami Microneedle (FAOM) Device for Quantitatively Monitoring Blood Glucose. Advanced Materials[J]. 2023, 第 15 作者 通讯作者 [14] Tian, Run, Shang, Yingxu, Wang, Yiming, Jiang, Qiao, Ding, Baoquan. DNA Nanomaterials-Based Platforms for Cancer Immunotherapy. SMALL METHODS. 2023, 第 5 作者 通讯作者 7(5): https://www.doi.org/10.1002/smtd.202201518.[15] Wu Xiaohui, Yang Changping, Wang Hong, Lu Xuehe, Shang Yingxu, Liu Qing, Fan Jing, Liu Jianbing, Ding Baoquan. Genetically Encoded DNA Origami for Gene Therapy In Vivo. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2023, 第 9 作者 通讯作者 145(16): 9343-9353, http://dx.doi.org/10.1021/jacs.3c02756.[16] Wu Tiantian, Wang Hong, Tian Run, Guo Shuang, Liao Yuhui, Liu Jianbing, Ding Baoquan. A DNA Origami-based Bactericide for Efficient Healing of Infected Wounds. Angewandte Chemie International Edition[J]. 2023, 第 7 作者 通讯作者 doi:10.1002/anie.202311698: [17] Qiao Jiang, Yingxu Shang, Yiming Xie, Baoquan Ding. DNA Origami: from Molecular Folding Art to Drug Delivery Technology. Advanced Materials[J]. 2023, 第 4 作者 通讯作者 doi:10.1002/adma.202301035: [18] Pitikultham, Piyawat, Wang, Zhaoran, Wang, Yiming, Shang, Yingxu, Jiang, Qiao, Ding, Baoquan. Stimuli-Responsive DNA Origami Nanodevices and Their Biological Applications. CHEMMEDCHEM. 2022, 第 6 作者 通讯作者 17(1): http://dx.doi.org/10.1002/cmdc.202100635.[19] Wu Tiantian, Cao Yuanwei, Liu Qing, Wu Xiaohui, Shang Yingxu, Piao Jiafang, Li Yujie, Dong Yuanchen, Liu Dongsheng, Wang Haoyi, Liu Jianbing, Ding Baoquan. Genetically Encoded Double-Stranded DNA-Based Nanostructure Folded by a Covalently Bivalent CRISPR/dCas System. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2022, 第 12 作者 通讯作者 144(14): 6575-6582, [20] Ma, Zhentao, Shang, Yingxu, Liu, Fengsong, Li, Na, Ding, Baoquan. Metal Nanostructures Based on DNA Origami Supramolecular Systems and Their Optical Properties. ACTA POLYMERICA SINICA. 2022, 第 5 作者 通讯作者 53(10): 1187-1203, [21] Yuang Wang, Xuehe Lu, Xiaohui Wu, Yan Li, Wantao Tang, Changping Yang, Jianbing Liu, Baoquan Ding. Chemically modified DNA nanostructures for drug delivery. THE INNOVATION[J]. 2022, 第 8 作者 通讯作者 3(2): 38-48, [22] Liu, Fengsong, Li, Na, Shang, Yingxu, Wang, Yiming, Liu, Qing, Ma, Zhentao, Jiang, Qiao, Ding, Baoquan. A DNA-Based Plasmonic Nanodevice for Cascade Signal Amplification. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, 第 8 作者 通讯作者 61(22): https://www.doi.org/10.1002/anie.202114706.[23] Yongjian Chen, Run Tian, Yingxu Shang, Qiao Jiang, Baoquan Ding. Regulation of Biological Functions at the Cell Interface by DNA Nanostructures. ADVANCED NANOBIOMED RESEARCH[J]. 2022, 第 5 作者2(2): n/a-n/a, https://doaj.org/article/9e109faf0f6a48a5a05ae1c7d714ee48.[24] Zhao, Weisong, Zhao, Shiqun, Li, Liuju, Huang, Xiaoshuai, Xing, Shijia, Zhang, Yulin, Qiu, Guohua, Han, Zhenqian, Shang, Yingxu, Sun, DeEn, Shan, Chunyan, Wu, Runlong, Gu, Lusheng, Zhang, Shuwen, Chen, Riwang, Xiao, Jian, Mo, Yanquan, Wang, Jianyong, Ji, Wei, Chen, Xing, Ding, Baoquan, Liu, Yanmei, Mao, Heng, Song, BaoLiang, Tan, Jiubin, Liu, Jian, Li, Haoyu, Chen, Liangyi. Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy. NATURE BIOTECHNOLOGY[J]. 2022, 第 21 作者40(4): 606-+, http://dx.doi.org/10.1038/s41587-021-01092-2.[25] Yunfei Jiao, Yingxu Shang, Na Li, Baoquan Ding. DNA-based enzymatic systems and their applications. ISCIENCE[J]. 2022, 第 4 作者 通讯作者 25(4): 104018, [26] Li Runze, Wu Xiaohui, Li Jing, Lu Xuehe, Zhao Robert Chunhua, Liu Jianbing, Ding Baoquan. A covalently conjugated branched DNA aptamer cluster-based nanoplatform for efficiently targeted drug delivery. NANOSCALE[J]. 2022, 第 7 作者 通讯作者 14: 9369-9378, [27] Zhu, Jinjin, Wu, Fan, Han, Zihong, Shang, Yingxu, Liu, Fengsong, Yu, Haiyin, Yu, Li, Li, Na, Ding, Baoquan. Strong Light-Matter Interactions in Chiral Plasmonic-Excitonic Systems Assembled on DNA Origami. NANO LETTERS[J]. 2021, 第 9 作者 通讯作者 21(8): 3573-3580, http://dx.doi.org/10.1021/acs.nanolett.1c00596.[28] Wang, Zhaoran, Song, Linlin, Liu, Qing, Tian, Run, Shang, Yingxu, Liu, Fengsong, Liu, Shaoli, Zhao, Shuai, Han, Zihong, Sun, Jiashu, Jiang, Qiao, Ding, Baoquan. A Tubular DNA Nanodevice as a siRNA/Chemo-Drug Co-delivery Vehicle for Combined Cancer Therapy. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2021, 第 12 作者 通讯作者 60(5): 2594-2598, http://dx.doi.org/10.1002/anie.202009842.[29] Liu Jianbing, Lu Xuehe, Wu Tiantian, Wu Xiaohui, Han Lin, Ding Baoquan. Branched Antisense and siRNA Co-Assembled Nanoplatform for Combined Gene Silencing and Tumor Therapy. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2021, 第 6 作者 通讯作者 60(4): 1853-1860, [30] Han Lin, Wang Yuang, Tang Wantao, Liu Jianbing, Ding Baoquan. Bioimaging Based on Nucleic Acid Nanostructures. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES[J]. 2021, 第 5 作者 通讯作者 37(4): 823-828, [31] 丁宝全. Nucleic acid–based aggregates and their biomedical applications. Aggregate. 2021, 第 1 作者 通讯作者 [32] Xu, Xuehui, Shang, Yingxu, Liu, Fengsong, Jiang, Qiao, Ding, Baoquan. Logic devices based on nucleic acid self-assembly. INFOMAT. 2021, 第 5 作者 通讯作者 3(10): 1070-1082, http://dx.doi.org/10.1002/inf2.12240.[33] Li Yan, Pei Jin, Lu Xuehe, Jiao Yunfei, Liu Fengsong, Wu Xiaohui, Liu Jianbing, Ding Baoquan. Hierarchical Assembly of Super-DNA Origami Based on a Flexible and Covalent-Bound Branched DNA Structure. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2021, 第 8 作者 通讯作者 143(47): 19893-19900, [34] Shuai Zhao, Run Tian, Jun Wu, Shaoli Liu, Yuanning Wang, Meng Wen, Yingxu Shang, Qing Liu, Yan Li, Ying Guo, Zhaoran Wang, Ting Wang, Yujing Zhao, Huiru Zhao, Hui Cao, Yu Su, Jiashu Sun, Qiao Jiang, Baoquan Ding. A DNA origami-based aptamer nanoarray for potent and reversible anticoagulation in hemodialysis. NATURE COMMUNICATIONS[J]. 2021, 第 19 作者 通讯作者 12(1): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7807036/.[35] Tian, Fei, Zhang, Shaohua, Liu, Chao, Han, Ziwei, Liu, Yuan, Deng, Jinqi, Li, Yike, Wu, Xia, Cai, Lili, Qin, Lili, Chen, Qinghua, Yuan, Yang, Liu, Yi, Cong, Yulong, Ding, Baoquan, Jiang, Zefei, Sun, Jiashu. Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer. NATURE COMMUNICATIONS[J]. 2021, 第 15 作者12(1): https://doaj.org/article/ad4f67eb76a945bbab6cae162e3f55be.[36] Han, Ziwei, Wan, Fangning, Deng, Jinqi, Zhao, Junxiang, Li, Yike, Yang, Yunjie, Jiang, Qiao, Ding, Baoquan, Liu, Chao, Dai, Bo, Sun, Jiashu. Ultrasensitive detection of mRNA in extracellular vesicles using DNA tetrahedron-based thermophoretic assay. NANO TODAY[J]. 2021, 第 8 作者38: http://dx.doi.org/10.1016/j.nantod.2021.101203.[37] Liu, Shaoli, Jiang, Qiao, Zhao, Xiao, Zhao, Ruifang, Wang, Yuanning, Wang, Yiming, Liu, Jianbing, Shang, Yingxu, Zhao, Shuai, Wu, Tiantian, Zhang, Yinlong, Nie, Guangjun, Ding, Baoquan. A DNA nanodevice-based vaccine for cancer immunotherapy. NATURE MATERIALS[J]. 2021, 第 13 作者 通讯作者 20(3): 421-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000566892000002.[38] Tang Wantao, Han Lin, Lu Xuehe, Wang Zhaoran, Liu Fengsong, Li Yan, Liu Shengbo, Liu, Shaoli, Tian Run, Liu Jianbing, Ding Baoquan. A Nucleic Acid/Gold Nanorod-Based Nanoplatform for Targeted Gene Editing and Combined Tumor Therapy. ACSAPPLIEDMATERIALSINTERFACES[J]. 2021, 第 11 作者 通讯作者 13(18): 20974-20981, [39] Tang Wantao, Han Lin, Duan Su, Lu Xuehe, Wang Yuang, Wu Xiaohui, Liu Jianbing, Ding Baoquan. An Aptamer-Modified DNA Tetrahedron-Based Nanogel for Combined Chemo/Gene Therapy of Multidrug-Resistant Tumors. ACS APPLIED BIO MATERIALS[J]. 2021, 第 8 作者 通讯作者 4(10): 7701-7707, [40] Pitikultham, Piyawat, Wang, Zhaoran, Wang, Yiming, Shang, Yingxu, Jiang, Qiao, Ding, Baoquan. Stimuli-Responsive DNA Origami Nanodevices and Their Biological Applications. CHEMMEDCHEM. 2021, 第 6 作者 通讯作者 [41] Wu, Xiaohui, Liu, Qing, Liu, Fengsong, Wu, Tiantian, Shang, Yingxu, Liu, Jianbing, Ding, Baoquan. An RNA/DNA hybrid origami-based nanoplatform for efficient gene therapy. NANOSCALE[J]. 2021, 第 7 作者 通讯作者 13(30): 12848-12853, [42] Song, Linlin, Wang, Zhaoran, Liu, Jianbing, Wang, Ting, Jiang, Qiao, Ding, Baoquan. Tumor-Targeted DNA Bipyramid for in Vivo Dual -Modality Imaging. ACS APPLIED BIO MATERIALS[J]. 2020, 第 6 作者 通讯作者 3(5): 2854-2860, http://dx.doi.org/10.1021/acsabm.9b01096.[43] Lu, Xuehe, Wu, Xiaohui, Wu, Tiantian, Han, Lin, Liu, Jianbing, Ding, Baoquan. Efficient construction of a stable linear gene based on a TNA loop modified primer pair for gene delivery. CHEMICAL COMMUNICATIONS[J]. 2020, 第 6 作者 通讯作者 56(68): 9894-9897, [44] Shang, Yingxu, Liu, Fengsong, Wang, Yuanning, Li, Na, Ding, Baoquan. Enzyme Mimic Nanomaterials and Their Biomedical Applications. CHEMBIOCHEM[J]. 2020, 第 5 作者 通讯作者 21(17): 2408-2418, http://dx.doi.org/10.1002/cbic.202000123.[45] Wu, Xiaohui, Wu, Tiantian, Liu, Jianbing, Ding, Baoquan. Gene Therapy Based on Nucleic Acid Nanostructure. ADVANCED HEALTHCARE MATERIALS[J]. 2020, 第 4 作者 通讯作者 9(19): [46] Shang, Yingxu, Li, Na, Liu, Shengbo, Wang, Ling, Wang, ZhenGang, Zhang, Zhong, Ding, Baoquan. Site-Specific Synthesis of Silica Nanostructures on DNA Origami Templates. ADVANCED MATERIALS[J]. 2020, 第 7 作者 通讯作者 32(21): https://www.webofscience.com/wos/woscc/full-record/WOS:000526806300001.[47] Liu, Fengsong, Shang, Yingxu, Wang, Zhaoran, Jiao, Yunfei, Li, Na, Ding, Baoquan. DNA origami directed fabrication of shape-controllable nanomaterials. APL MATERIALS[J]. 2020, 第 6 作者 通讯作者 8(11): https://doaj.org/article/1a237e9ea71344f59be0e7cf584b0ce3.[48] Wu, Tiantian, Liu, Qing, Cao, Yuanwei, Tian, Run, Liu, Jianbing, Ding, Baoquan. Multifunctional Double-Bundle DNA Tetrahedron for Efficient Regulation of Gene Expression. ACS APPLIED MATERIALS & INTERFACES[J]. 2020, 第 6 作者 通讯作者 12(29): 32461-32467, [49] Zhu Jinjin, Shang Yingxu, Yu Haiyin, Li Na, Ding Baoquan. Shape-controllable Synthesis of Functional Nanomaterials on DNA Templates. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES[J]. 2020, 第 5 作者 通讯作者 36(2): 171-176, http://lib.cqvip.com/Qikan/Article/Detail?id=7101349529.[50] 丁宝全. Cofactor-freeoxidase-mimeticnanomaterials fromself-assembled histidine-rich peptides. Nature Materials. 2020, 第 1 作者 通讯作者 [51] 丁宝全. Logic gated plasmonic nanodevices based on DNA-templated assembly. CCS Chemistry. 2020, 第 1 作者 通讯作者 [52] 丁宝全. Strong Plasmon-Exciton Coupling in Bimetallic Nanoring and Nanocuboids. Journal of Materials Chemistry C. 2020, 第 1 作者 通讯作者 [53] Li, Na, Wu, Fan, Han, Zihong, Wang, Xiaofeng, Liu, Yi, Yi, Chenglin, Ye, Shunsheng, Lu, Guowei, Yu, Li, Nie, Zhihong, Ding, Baoquan. Shape Complementarity Modulated Self-Assembly of Nanoring and Nanosphere Hetero-nanostructures. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2020, 第 11 作者 通讯作者 142(27): 11680-11684, http://dx.doi.org/10.1021/jacs.0c04678.[54] Li, Na, Han, Zihong, Huang, Yuming, Liang, Kun, Wang, Xiaofeng, Wu, Fan, Qi, Xiaoying, Shang, Yingxu, Yu, Li, Ding, Baoquan. Strong plasmon-exciton coupling in bimetallic nanorings and nanocuboids. JOURNAL OF MATERIALS CHEMISTRY C[J]. 2020, 第 10 作者 通讯作者 8(23): 7672-7678, https://www.webofscience.com/wos/woscc/full-record/WOS:000544086800005.[55] 丁宝全. A Multifunctional Double Bundle DNA Tetrahedron for Efficient Regulation of Gene Expression. ACS Applied Materials & Interfaces. 2020, 第 1 作者 通讯作者 [56] Li, Na, Shang, Yingxu, Han, Zihong, Wang, Ting, Wang, ZhenGang, Ding, Baoquan. Fabrication of Metal Nanostructures on DNA Templates. ACS APPLIED MATERIALS & INTERFACES. 2019, 第 6 作者 通讯作者 11(15): 13835-13852, https://www.webofscience.com/wos/woscc/full-record/WOS:000465189000002.[57] Liu, Shaoli, Jiang, Qiao, Wang, Yuanning, Ding, Baoquan. Biomedical Applications of DNA-Based Molecular Devices. ADVANCED HEALTHCARE MATERIALS. 2019, 第 4 作者 通讯作者 8(10): https://www.webofscience.com/wos/woscc/full-record/WOS:000468803300012.[58] Lu, Xuehe, Liu, Jianbing, Wu, Xiaohui, Ding, Baoquan. Multifunctional DNA Origami Nanoplatforms for Drug Delivery. CHEMISTRY-AN ASIAN JOURNAL[J]. 2019, 第 4 作者 通讯作者 14(13): 2193-2202, [59] Liu, Chao, Zhao, Junxiang, Tian, Fei, Cai, Lili, Zhang, Wei, Feng, Qiang, Chang, Jianqiao, Wan, Fangning, Yang, Yunjie, Dai, Bo, Cong, Yulong, Ding, Baoquan, Sun, Jiashu, Tan, Weihon. Low-cost thermophoretic profiling of extracellular-vesicle surface proteins for the early detection and classification of cancers. NATURE BIOMEDICAL ENGINEERING[J]. 2019, 第 12 作者3(3): 183-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000460576800009.[60] 聂广军, 蒋乔, 李素萍, 丁宝全, 赵宇亮. DNA纳米机器人:第一次在活体内高效完成定点药物输运. 前沿科学[J]. 2019, 第 4 作者13(1): 22-24, http://lib.cqvip.com/Qikan/Article/Detail?id=7001829940.[61] Jiang, Qiao, Zhao, Shuai, Liu, Jianbing, Song, Linlin, Wang, ZhenGang, Ding, Baoquan. Rationally designed DNA-based nanocarriers. ADVANCED DRUG DELIVERY REVIEWS. 2019, 第 6 作者 通讯作者 147: 2-21, http://dx.doi.org/10.1016/j.addr.2019.02.003.[62] Jiang, Qiao, Liu, Shaoli, Liu, Jianbing, Wang, ZhenGang, Ding, Baoquan. Rationally Designed DNA-Origami Nanomaterials for Drug Delivery In Vivo. ADVANCED MATERIALS[J]. 2019, 第 5 作者 通讯作者 31(45): [63] Wu, Tiantian, Liu, Jianbing, Liu, Manman, Liu, Shaoli, Zhao, Shuai, Tian, Run, Wei, Dengshuai, Liu, Yangzhong, Zhao, Yao, Xiao, Haihua, Ding, Baoquan. A Nanobody-Conjugated DNA Nanoplatform for Targeted Platinum-Drug Delivery. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 第 11 作者 通讯作者 58(40): 14224-14228, [64] Li, Na, Shang, Yingxu, Xu, Rui, Jiang, Qiao, Liu, Jianbing, Wang, Ling, Cheng, Zhihai, Ding, Baoquan. Precise Organization of Metal and Metal Oxide Nanoclusters into Arbitrary Patterns on DNA Origami. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2019, 第 8 作者 通讯作者 141(45): 17968-17972, https://www.webofscience.com/wos/woscc/full-record/WOS:000498281600003.[65] Jiang, Qiao, Xu, Xuehui, Yin, PingAn, Ma, Kai, Zhen, Yonggang, Duan, Pengfei, Peng, Qian, Chen, WeiQiang, Ding, Baoquan. 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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2012, 第 7 作者134(1): 146-149, http://dx.doi.org/10.1021/ja209861x.[124] Jiang, Qiao, Song, Chen, Nangreave, Jeanette, Liu, Xiaowei, Lin, Lin, Qiu, Dengli, Wang, ZhenGang, Zou, Guozhang, Liang, Xingjie, Yan, Hao, Ding, Baoquan. DNA Origami as a Carrier for Circumvention of Drug Resistance. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2012, 第 11 作者134(32): 13396-13403, https://www.webofscience.com/wos/woscc/full-record/WOS:000307487200044.[125] Alloyeau, Damien, Ding, Baoquan, Ramasse, Quentin, Kisielowski, Christian, Lee, Zonghoon, Jeon, KiJoon. Direct imaging and chemical analysis of unstained DNA origami performed with a transmission electron microscope. CHEMICAL COMMUNICATIONS[J]. 2011, 第 2 作者47(33): 9375-9377, https://www.webofscience.com/wos/woscc/full-record/WOS:000293648200025.[126] Ding, Baoquan, Wu, Hao, Xu, Wei, Zhao, Zhao, Liu, Yan, Yu, Hongbin, Yan, Hao. Interconnecting Gold Islands with DNA Origami Nanotubes. NANO LETTERS[J]. 2010, 第 1 作者10(12): 5065-5069, https://www.webofscience.com/wos/woscc/full-record/WOS:000284990900049.[127] Pal, Suchetan, Deng, Zhengtao, Ding, Baoquan, Yan, Hao, Liu, Yan. DNA-Origami-Directed Self-Assembly of Discrete Silver-Nanoparticle Architectures. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2010, 第 3 作者49(15): 2700-2704, https://www.webofscience.com/wos/woscc/full-record/WOS:000276780500008.[128] 丁宝全. Gold Nanoparticles Self-similar Chain Structure Organized by DNA Origami. J. Am. Chem. Soc.. 2010, 第 1 作者 通讯作者 [129] Deng, Zhengtao, Schulz, Olaf, Lin, Su, Ding, Baoquan, Liu, Xiaowei, Wei, XiXi, Ros, Robert, Yan, Hao, Liu, Yan. Aqueous Synthesis of Zinc Blende CdTe/CdS Magic-Core/Thick-Shell Tetrahedral-Shaped Nanocrystals with Emission Tunable to Near-Infrared. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2010, 第 4 作者132(16): 5592-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000276991700029.[130] 丁宝全. DNA Directed Assembly of Nanoparticles Linear Structure for Nanophotonics. Journal of Vacuum Science and Technology B. 2009, 第 1 作者 通讯作者 [131] Ding, Baoquan, Seeman, Nadrian C. Operation of a DNA robot arm inserted into a 2D DNA crystalline substrate. SCIENCE[J]. 2006, 第 1 作者314(5805): 1583-1585, https://www.webofscience.com/wos/woscc/full-record/WOS:000242624600037.[132] Ding, BQ, Sha, RJ, Seeman, NC. Pseudohexagonal 2D DNA crystals from double crossover cohesion. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2004, 126(33): 10230-10231, https://www.webofscience.com/wos/woscc/full-record/WOS:000223433700019.
科研活动
科研项目
( 1 ) 中国科学院****,结构DNA 纳米技术的研究, 主持, 部委级, 2011-01--2013-12( 2 ) DNA 折纸结构模板引导的金属和半导体纳米粒子精确自组装结构及其在等离子体器件与灵敏检测中的应用, 主持, 国家级, 2012-01--2015-12( 3 ) DNA 折纸结构模板引导的金属纳米粒子手性螺旋链的自组装, 主持, 国家级, 2012-01--2014-12( 4 ) 科技部纳米重大研究计划项目,基于肿瘤微环境调控的抗肿瘤纳米材料设计和机制研究, 参与, 国家级, 2012-01--2016-12( 5 ) 生物纳米材料, 主持, 国家级, 2013-01--2015-12( 6 ) 万人计划青年拔尖人才, 主持, 国家级, 2016-01--2019-12( 7 ) 肿瘤微环境调控型智能纳米材料, 主持, 部委级, 2016-01--2018-12( 8 ) DNA纳米模板引导的抗体蛋白精确自组装结构及其作为肿瘤治疗平台的研究, 主持, 国家级, 2016-01--2019-12( 9 ) 核酸纳米结构作为高效抗肿瘤光热转换材料运输载体的研究, 主持, 省级, 2014-01--2016-12( 10 ) DNA折纸纳米结构作为肿瘤药物靶向性输送载体的设计与制造, 主持, 省级, 2012-01--2014-12
指导学生
已指导学生
刘清 02 63228
蒋乔 01 20652
邹翊国 02 20652
刘欢 02 63222
现指导学生
宋琳琳 01 20652
李彤彤 02 19217
湛鹏飞 01 20652
刘清 01 20652
徐雪卉 02 19184
段方圆 02 67922
赵帅 02 67921
韩梓弘 02 20652
尚颖旭 01 20652
课题组介绍
课题组在2010年成立,目前实验室有副研究员1名,助理研究员两名,纳米中心在校学生8名,联合培养学生3名,博士后学生一名。本课题组在丁宝全研究员带领下,致力于DNA折纸术的合理设计与制备,及自组装的生物纳米材料与电子束光刻等方法向结合制备的纳米器件的研究,并且取得了一系列创新性成果,已在JACS,Nano Letters,ACS Nano等重要期刊发表论文,并与多个实验室建立了良好的合作关系。我们课题组有着对知识的渴求,对科研的追求,以及踏实认真的学习态度,欢迎对纳米材料等前沿研究领域感兴趣并热爱科研的本科生、研究生、博士生加入本课题组, 我们也热忱欢迎海内外企业、科研机构及专家、学者来课题组访问、交流、合作。
2014年与毕业生合影留念
刘清师兄与蒋乔师姐毕业合影留念
2015年与毕业生合影留念
邹翊国师兄毕业合影
与Nadrian C. Seeman 教授相聚
课题组部分成员与Nadrian C. Seeman 教授
课题组成员
课题组成员