基本信息
崔菊 女 博导 其他
电子邮件： cuiju4366@bjhmoh.cn
通信地址： 北京东城区东单大华路1号北京医院
邮政编码：
电子邮件： cuiju4366@bjhmoh.cn
通信地址： 北京东城区东单大华路1号北京医院
邮政编码：
招生信息
招生专业
100104-病理学与病理生理学
招生方向
衰老与肿瘤发病机制及干预研究
健康影响因素人群队列研究
衰老定量评价体系及衰老标志物研究
健康影响因素人群队列研究
衰老定量评价体系及衰老标志物研究
教育背景
2007-10--2010-09 香港大学 博士
2005-08--2007-07 香港中文大学 硕士
2001-09--2005-06 浙江大学 学士
2005-08--2007-07 香港中文大学 硕士
2001-09--2005-06 浙江大学 学士
工作经历
工作简历
2022-08~现在, 北京医院, 研究员
2017-08~2022-07,北京医院, 副研究员
2012-09~2016-07,北京医院, 助理研究员
2010-11~2012-06,香港大学, 博士后
2017-08~2022-07,北京医院, 副研究员
2012-09~2016-07,北京医院, 助理研究员
2010-11~2012-06,香港大学, 博士后
专利与奖励
奖励信息
（1） 马达蛋白Kif5b调节肾小管上皮细胞极性形成的作用及机制研究, 三等奖, 研究所（学校）, 2015
专利成果
（ 1 ） 一种防止肿瘤的药物及其用途, 发明专利, 2019, 第 5 作者, 专利号: ZL 2016 1 0491656.7
（ 2 ） Tumor prevention and treatment drug and applications thereof., 发明专利, 2019, 第 5 作者, 专利号: US 10,335,427 B2
（ 2 ） Tumor prevention and treatment drug and applications thereof., 发明专利, 2019, 第 5 作者, 专利号: US 10,335,427 B2
出版信息
发表论文
[1] 刘媛媛, 王瑶, 霍达, 李雪飞, 曾律滔, 范国庆, 张立群, 庞婧, 蔡剑平, 崔菊. 血清内脂素作为人体衰老标志物的相关性研究. 医学研究杂志[J]. 2024, 第 10 作者 通讯作者
[2] Chi Zhang, Ju Cui, Shaojie Li, Ji Shen, Xuanmei Luo, Yao Yao, Hong Shi. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults. BMC GERIATRICS. 2024, 第 2 作者24: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10836043/.
[3] Rong Zhang, Lei Li, Huihui Li, Hansong Bai, Yuping Suo, Ju Cui, Yingmei Wang. Ginsenoside 20(S)-Rg3 reduces KIF20A expression and promotes CDC25A proteasomal degradation in epithelial ovarian cancer. JOURNAL OF GINSENG RESEARCH[J]. 2024, 第 6 作者 通讯作者 48(1): 40-51, http://dx.doi.org/10.1016/j.jgr.2023.06.008.
[4] Huo, Da, Liu, YuanYuan, Zhang, Chi, Zeng, LvTao, Fan, GuoQing, Zhang, LiQun, Pang, Jing, Wang, Yao, Shen, Tao, Li, XueFei, Li, ChuanBao, Zhang, TieMei, Cai, JianPing, Cui, Ju. Serum glycoprotein non-metastatic melanoma protein B (GPNMB) level as a potential biomarker for diabetes mellitus-related cataract: A cross-sectional study. FRONTIERS IN ENDOCRINOLOGY[J]. 2023, 第 14 作者 通讯作者 14: http://dx.doi.org/10.3389/fendo.2023.1110337.
[5] Fan Guoqing, Li Danni, Liu Jingjing, Tao Ningning, Meng Chao, Cui Ju, Cai Jianping, Sun Tieying. HNRNPD is a prognostic biomarker in non-small cell lung cancer and affects tumor growth and metastasis via the PI3K-AKT pathway. Biotechnology and Genetic Engineering Reviews[J]. 2023, 第 6 作者27: 1-20,
[6] Li, Jin, Zhang, He, Wang, ZhenHe, Li, YunXuan, Zhang, LiQun, Cui, Ju, Li, DanNi, Wang, ZiHui, Liu, Qian, Liu, Zhen, Iwakuma, Tomoo, Cai, JianPing. 8-oxo-dGTP curbs tumor development via S phase arrest and AIF-mediated apoptosis. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2023, 第 6 作者196: 53-64, http://dx.doi.org/10.1016/j.freeradbiomed.2023.01.012.
[7] Sun, Shenghui, Xu, Kun, Yan, Mingjing, Cui, Ju, Zhu, Kaiyi, Yang, Yao, Zhang, Xiaoyi, Tang, Weiqing, Huang, Xiuqing, Dou, Lin, Chen, Beidong, Lin, Yajun, Zhang, Xiyue, Man, Yong, Li, Jian, Shen, Tao. Delphinidin induces autophagic flux blockage and apoptosis by inhibiting both multidrug resistance gene 1 and DEAD-box helicase 17 expressions in liver cancer cells. JOURNAL OF PHARMACY AND PHARMACOLOGY[J]. 2023, 第 4 作者75(2): 253-263, http://dx.doi.org/10.1093/jpp/rgac037.
[8] Jiang, Shan, Cui, Ju, Zhang, LiQun, Liu, Zhen, Zhang, Yan, Shi, Yuan, Cai, JianPing. Role of a Urinary Biomarker in the Common Mechanism of Physical Performance and Cognitive Function. FRONTIERS IN MEDICINE[J]. 2022, 第 2 作者9: http://dx.doi.org/10.3389/fmed.2022.816822.
[9] Liu, YuanYuan, Huo, Da, Zeng, LvTao, Fan, GuoQing, Shen, Tao, Zhang, TieMei, Cai, JianPing, Cui, Ju. Mesencephalic astrocyte-derived neurotrophic factor (MANF): Structure, functions and therapeutic potential. AGEING RESEARCH REVIEWS. 2022, 第 8 作者 通讯作者 82: http://dx.doi.org/10.1016/j.arr.2022.101763.
[10] Xu, Kun, Sun, Shenghui, Yan, Mingjing, Cui, Ju, Yang, Yao, Li, Wenlin, Huang, Xiuqing, Dou, Lin, Chen, Beidong, Tang, Weiqing, Lan, Ming, Li, Jian, Shen, Tao. DDX5 and DDX17-multifaceted proteins in the regulation of tumorigenesis and tumor progression. FRONTIERS IN ONCOLOGY. 2022, 第 4 作者12: http://dx.doi.org/10.3389/fonc.2022.943032.
[11] 陈爱群, 蔡剑平, 崔菊. IgG4相关性米库力兹综合征1例及其血浆细胞因子研究. 中华老年医学杂志[J]. 2022, 第 3 作者41(3): 335-337, http://lib.cqvip.com/Qikan/Article/Detail?id=7106906731.
[12] Weng, Qinghua, Chen, Chaojie, Xiong, Jianhua, Liu, YaNan, Pan, Xinxin, Cui, Ju, Cai, JianPing, Xu, RenAi. Effect of Baicalein on the Pharmacokinetics of Cilostazol and Its Two Metabolites in Rat Plasma Using UPLC-MS/MS Method. FRONTIERS IN PHARMACOLOGY[J]. 2022, 第 6 作者 通讯作者 13: http://dx.doi.org/10.3389/fphar.2022.888054.
[13] Zhang, He, Jiang, Pengjun, Lv, Mengyuan, Zhao, Yanhua, Cui, Ju, Chen, Jie. OGG1 contributes to hepatocellular carcinoma by promoting cell cycle-related protein expression and enhancing DNA oxidative damage repair in tumor cells. JOURNAL OF CLINICAL LABORATORY ANALYSIS[J]. 2022, 第 5 作者 通讯作者 36(7): http://dx.doi.org/10.1002/jcla.24561.
[14] Zhang, Chi, Hao, Jinjuan, Liu, Ye, Cui, Ju, Yu, Hao. Associations Between Online Learning, Smartphone Addiction Problems, and Psychological Symptoms in Chinese College Students After the COVID-19 Pandemic. FRONTIERS IN PUBLIC HEALTH[J]. 2022, 第 4 作者 通讯作者 10: http://dx.doi.org/10.3389/fpubh.2022.881074.
[15] Yuan, Lingjing, Qian, Jianchang, Li, Xiangyu, Cui, Ju, Cai, Jianping, Hu, Guoxin. Enzymatic activity on valsartan of 38 CYP2C9 variants from the Chinese population. CHEMICO-BIOLOGICAL INTERACTIONS[J]. 2022, 第 4 作者353: http://dx.doi.org/10.1016/j.cbi.2022.109799.
[16] Li, DanNi, Yang, ChengCheng, Li, Jin, Yang, QiuGeng Ou, Zeng, LvTao, Fan, GuoQing, Liu, TengHui, Tian, XinYuan, Wang, JingJing, Zhang, He, Dai, DaPeng, Cui, Ju, Cai, JianPing. The high expression of MTH1 and NUDT5 promotes tumor metastasis and indicates a poor prognosis in patients with non-small-cell lung cancer. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH[J]. 2021, 第 12 作者1868(1): http://dx.doi.org/10.1016/j.bbamcr.2020.118895.
[17] Huo, Da, Yang, Hua, Huang, JianDong, Cai, JianPing, Cui, Ju. Roles of kinesin superfamily proteins in colorectal cancer carcinogenesis. ONCOLOGY REPORTS. 2021, 第 5 作者 通讯作者 46(1): http://dx.doi.org/10.3892/or.2021.8072.
[18] Zhang, He, Zhang, LiQun, Yang, ChengCheng, Li, Jin, Tian, XinYuan, Li, DanNi, Cui, Ju, Cai, JianPing. The high expression of NUDT5 indicates poor prognosis of breast cancer by modulating AKT / Cyclin D signaling. PLOS ONE[J]. 2021, 第 7 作者16(2): https://doaj.org/article/ebdda09c9dcb41bba3000892310bf1b8.
[19] Zhang, Chi, Zeng, Ping, Tan, Joshua, Sun, Siwei, Zhao, Minghao, Cui, Ju, Zhang, Guifang, Jia, Jinzhong, Liu, Deping. Relationship of Problematic Smartphone Use, Sleep Quality, and Daytime Fatigue Among Quarantined Medical Students During the COVID-19 Pandemic. FRONTIERS IN PSYCHIATRY[J]. 2021, 第 6 作者12: http://dx.doi.org/10.3389/fpsyt.2021.755059.
[20] 霍达, 刘晶晶, 范国庆, 曾律滔, 刘媛媛, 蔡剑平, 黄建东, 崔菊. KIF5B过表达和干扰慢病毒载体的构建及对结直肠癌细胞增殖的影响. 医学研究杂志[J]. 2021, 第 8 作者 通讯作者 50(12): 43-48, http://lib.cqvip.com/Qikan/Article/Detail?id=7106257236.
[21] Yu, Xiaoxue, Ruan, Yang, Huang, Xiuqing, Dou, Lin, Lan, Ming, Cui, Ju, Chen, Beidong, Gong, Huan, Wang, Que, Yan, Mingjing, Sun, Shenghui, Qiu, Quan, Zhang, Xiyue, Man, Yong, Tang, Weiqing, Li, Jian, Shen, Tao. Dexrazoxane ameliorates doxorubicin-induced cardiotoxicity by inhibiting both apoptosis and necroptosis in cardiomyocytes. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2020, 第 6 作者523(1): 140-146, http://dx.doi.org/10.1016/j.bbrc.2019.12.027.
[22] 范国庆, 欧阳秋庚, 曾律滔, 崔菊, 奚桓, 蔡剑平. 脂联素在小鼠各脏器组织中增龄性变化的研究. 中华老年医学杂志[J]. 2020, 第 4 作者39(5): 582-586, http://lib.cqvip.com/Qikan/Article/Detail?id=7101921560.
[23] 向云青, 权菲菲, 温慧, 袁国栋, 崔菊, 黄术强. 基于仿生微流控技术的肠道器官芯片构建. 集成技术[J]. 2020, 第 5 作者 通讯作者 9(3): 56-65, http://lib.cqvip.com/Qikan/Article/Detail?id=7102046489.
[24] 曾律滔, 范国庆, 欧阳秋庚, 崔菊, 蔡剑平. LOX-1作为潜在的肺特异性衰老标志物的相关研究. 医学研究杂志[J]. 2020, 第 4 作者49(7): 22-26, http://lib.cqvip.com/Qikan/Article/Detail?id=7102380742.
[25] Zhao, Ban, Chen, Aiqun, Wang, Haitao, Cui, Ju, Sun, Ying, Xu, Lengnan, Mao, Yonghui. The relationship between sclerostin and carotid artery atherosclerosis in patients with stage 3-5 chronic kidney disease. INTERNATIONAL UROLOGY AND NEPHROLOGY[J]. 2020, 第 4 作者52(7): 1329-1336, https://www.webofscience.com/wos/woscc/full-record/WOS:000542720500017.
[26] Zhang, LiQun, Xiao, Yao, Zhou, XiaoYang, Cui, Ju, Cai, JianPing. Characterization of the novel HLA-DRB1*11:245 allele by sequencing-based typing. HLA. 2019, 第 4 作者93(2-3): 133-+,
[27] Zhang, LiQun, Xiao, Yao, Zhou, XiaoYang, Cui, Ju, Cai, JianPing. Characterization of the novel HLA-DQB1*03:01:45 allele by sequencing-based typing. HLA. 2019, 第 4 作者93(2-3): 136-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000462256400027.
[28] Lin, Raozhou, Duan, Zhigang, Sun, Haitao, Fung, ManLung, Chen, Hansen, Wang, Jing, Lau, ChiFai, Yang, Di, Liu, Yu, Ni, Yanxiang, Wang, Zai, Cui, Ju, Wu, Wutian, Yung, WingHo, Chan, YingShing, Lo, Amy C Y, Xia, Jun, Shen, Jiangang, Huang, JianDong. Kinesin-1 Regulates Extrasynaptic Targeting of NMDARs and Neuronal Vulnerability Toward Excitotoxicity. ISCIENCE[J]. 2019, 第 12 作者13: 82-+, http://dx.doi.org/10.1016/j.isci.2019.02.009.
[29] Yinghui Li, Xiangran Lu, Qianmeng Lin, Huanle Huang, Xiaolong Liang, Jianping Cai, Ju Cui, Guoxin Hu. Functional characterization of 27 CYP3A4 variants on macitentan metabolism in vitro. Journal of Pharmacy and Pharmacology[J]. 2019, 第 7 作者 通讯作者 71(11): 1677-1683, https://www.doi.org/10.1111/jphp.13153.
[30] Sun, Jingyu, Zhang, Yang, Zhen, Yongzhan, Cui, Ju, Hu, Gang, Lin, Yajun. Antitumor activity of tetrandrine citrate in human glioma U87 cells in vitro and in vivo. ONCOLOGY REPORTS[J]. 2019, 第 4 作者42(6): 2345-2354,
[31] Liu, Tong, Cai, JianPing, Zhang, LiQun, Sun, Ning, Cui, Ju, Wang, Hua, Yang, JieFu. The mechanism of RNA oxidation involved in the development of heart failure. FREE RADICAL RESEARCH[J]. 2019, 第 5 作者53(8): 910-921, http://dx.doi.org/10.1080/10715762.2019.1646424.
[32] Liu, Jiang, Zhen, YongZhan, Cui, Ju, Hu, Gang, Wei, Jie, Xu, Rong, Tu, Ping, Lin, YaJun. Dynamic influence of Rhein lysinate on HeLa cells. INTERNATIONAL JOURNAL OF ONCOLOGY[J]. 2018, 第 3 作者53(5): 2047-2055, https://www.webofscience.com/wos/woscc/full-record/WOS:000447703300018.
[33] Pang, Jing, Cui, Ju, Xi, Chao, Shen, Tao, Gong, Huan, Dou, Lin, Lin, Yajun, Zhang, Tiemei. Inhibition of Poly(ADP-Ribose) Polymerase Increased Lipid Accumulation Through SREBP1 Modulation. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY[J]. 2018, 第 2 作者49(2): 645-652, https://doaj.org/article/038718dd19d34cf69d14b0590a18b33c.
[34] Chen, Aiqun, Sun, Ying, Cui, Ju, Zhao, Ban, Wang, Haitao, Chen, Xianguang, Mao, Yonghui. Associations of sclerostin with carotid artery atherosclerosis and all-cause mortality in Chinese patients undergoing maintenance hemodialysis. BMC NEPHROLOGY[J]. 2018, 第 3 作者19(1): https://doaj.org/article/1d4360f2263c4474a6d3ad53ad909c2b.
[35] Cui, Ju, Pang, Jing, Lin, YaJun, Gong, Huan, Wang, ZhenHe, Li, YunXuan, Li, Jin, Wang, Zai, Jiang, Ping, Dai, DaPeng, Li, Jian, Cai, JianPing, Huang, JianDong, Zhang, TieMei. Adipose-specific deletion of Kif5b exacerbates obesity and insulin resistance in a mouse model of diet-induced obesity. FASEB JOURNAL[J]. 2017, 第 1 作者31(6): 2533-2547,
[36] 崔菊, 陈爱群, 庞婧, 李瑾, 李云炫, 张铁梅, 蔡剑平. 高脂饮食影响小鼠体内能量代谢的性别差异. 山西医科大学学报[J]. 2017, 第 1 作者48(7): 658-664, http://lib.cqvip.com/Qikan/Article/Detail?id=672836688.
[37] Li, Jin, Yang, ChengCheng, Tian, XinYuan, Li, YunXuan, Cui, Ju, Chen, Zhe, Deng, ZhouLu, Chen, FuJun, Hayakawa, Hiroshi, Sekiguchi, Mutsuo, Cai, JianPing. MutT-related proteins are novel progression and prognostic markers for colorectal cancer. ONCOTARGET[J]. 2017, 第 5 作者8(62): 105714-105726, http://dx.doi.org/10.18632/oncotarget.22393.
[38] 崔菊. 驱动蛋白-1在小鼠脂肪组织糖脂代谢中的作用研究. 现代生物医学进展. 2017, 第 1 作者
[39] 崔菊, 庞静, 宫环, 蔡剑平, 张铁梅. GLUT4和脂联素在3T3-L1脂肪细胞中共享囊泡转运机制. 医学研究杂志[J]. 2017, 第 1 作者46(3): 18-21, http://lib.cqvip.com/Qikan/Article/Detail?id=671719552.
[40] Wei, Jie, Zhen, YongZhan, Cui, Ju, He, FaLin, Shen, Tao, Hu, Gang, Ren, XiaoHong, Lin, YaJun. Rhein lysinate decreases inflammation and adipose infiltration in KK/HlJ diabetic mice with non-alcoholic fatty liver disease. ARCHIVES OF PHARMACAL RESEARCH[J]. 2016, 第 3 作者39(7): 960-969, https://www.webofscience.com/wos/woscc/full-record/WOS:000379692900010.
[41] Pang, Jing, Xi, Chao, Huang, Xiuqing, Cui, Ju, Gong, Huan, Zhang, Tiemei. Effects of Excess Energy Intake on Glucose and Lipid Metabolism in C57BL/6 Mice. PLOS ONE[J]. 2016, 第 4 作者11(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000367815600075.
[42] Cui Ju. Conventional kinesin KIF5B mediates adiponectin secretion in 3T3-L1 adipocyte. Biochem Biophys Res Commun. 2016, 第 1 作者
[43] 崔菊, 金国祥, 雷霆, 王在, 黄建东, 蔡剑平. 沉默Kif5b赋予MDCK细胞干性. 医学研究杂志[J]. 2016, 第 1 作者45(5): 58-62, http://lib.cqvip.com/Qikan/Article/Detail?id=668934986.
[44] Cui, Ju, Jin, Guoxiang, Yu, Bin, Wang, Zai, Lin, Raozhou, Huang, JianDong. Stable knockdown of Kif5b in MDCK cells leads to epithelial-mesenchymal transition. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2015, 第 1 作者 通讯作者 463(1-2): 123-129, https://www.webofscience.com/wos/woscc/full-record/WOS:000356753400021.
[45] Pang, Jing, Cui, Ju, Gong, Huan, Xi, Chao, Zhang, Tiemei. Effect of NAD on PARP-Mediated Insulin Sensitivity in Oleic Acid Treated Hepatocytes. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2015, 第 2 作者230(7): 1607-1613, https://www.webofscience.com/wos/woscc/full-record/WOS:000351842500021.
[46] Cui, Ju, Li, Xiuling, Duan, Zhigang, Xue, Wenqian, Wang, Zai, Lu, Song, Lin, Raozhou, Liu, Mengfei, Zhu, Guixia, Huang, JianDong. Analysis of Kif5b Expression during Mouse Kidney Development. PLOSONE[J]. 2015, 第 1 作者 通讯作者 10(4): https://doaj.org/article/2268a5e7e82048edb4c6c12d22e4bdb8.
[47] Jiandong Huang, Zai Wang, Ju Cui, Wutian Wu. Molecular motor protein kinesin-1 controls the localization of mitochondria and myofibrils components. BBA - BIOENERGETICS. 2014, 第 3 作者1837: e27-e27, http://dx.doi.org/10.1016/j.bbabio.2014.05.297.
[48] Cui, Ju, Wu, Long Tao, Chu, Ka Hou. Comparative proteomic profiling during ovarian development of the shrimp Metapenaeus ensis. MOLECULAR BIOLOGY REPORTS[J]. 2014, 第 1 作者 通讯作者 41(1): 519-528, https://www.webofscience.com/wos/woscc/full-record/WOS:000329100500056.
[49] Cui, Ju, Wu, Longtao, Chan, SiuMing, Chu, Ka Hou. cDNA cloning and mRNA expression of retinoid-X-receptor in the ovary of the shrimp Metapenaeus ensis. MOLECULAR BIOLOGY REPORTS[J]. 2013, 第 1 作者40(11): 6233-6244, https://www.webofscience.com/wos/woscc/full-record/WOS:000325948900020.
[50] Wang, Zai, Cui, Ju, Wong, Wai Man, Li, Xiuling, Xue, Wenqian, Lin, Raozhou, Wang, Jing, Wang, Peigang, Tanner, Julian A, Cheah, Kathryn S E, Wu, Wutian, Huang, JianDong. Kif5b controls the localization of myofibril components for their assembly and linkage to the myotendinous junctions. DEVELOPMENT[J]. 2013, 第 2 作者140(3): 617-626, https://www.webofscience.com/wos/woscc/full-record/WOS:000313363500015.
[51] Cui, Ju, Wang, Zai, Cheng, Qianni, Lin, Raozhou, Zhang, XinMei, Leung, Po Sing, Copeland, Neal G, Jenkins, Nancy A, Yao, KwokMing, Huang, JianDong. Targeted Inactivation of Kinesin-1 in Pancreatic beta-Cells In Vivo Leads to Insulin Secretory Deficiency. DIABETES[J]. 2011, 第 1 作者60(1): 320-330, https://www.webofscience.com/wos/woscc/full-record/WOS:000286017300039.
[2] Chi Zhang, Ju Cui, Shaojie Li, Ji Shen, Xuanmei Luo, Yao Yao, Hong Shi. Combined effects of vitamin D deficiency and systemic inflammation on all-cause mortality and cause-specific mortality in older adults. BMC GERIATRICS. 2024, 第 2 作者24: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10836043/.
[3] Rong Zhang, Lei Li, Huihui Li, Hansong Bai, Yuping Suo, Ju Cui, Yingmei Wang. Ginsenoside 20(S)-Rg3 reduces KIF20A expression and promotes CDC25A proteasomal degradation in epithelial ovarian cancer. JOURNAL OF GINSENG RESEARCH[J]. 2024, 第 6 作者 通讯作者 48(1): 40-51, http://dx.doi.org/10.1016/j.jgr.2023.06.008.
[4] Huo, Da, Liu, YuanYuan, Zhang, Chi, Zeng, LvTao, Fan, GuoQing, Zhang, LiQun, Pang, Jing, Wang, Yao, Shen, Tao, Li, XueFei, Li, ChuanBao, Zhang, TieMei, Cai, JianPing, Cui, Ju. Serum glycoprotein non-metastatic melanoma protein B (GPNMB) level as a potential biomarker for diabetes mellitus-related cataract: A cross-sectional study. FRONTIERS IN ENDOCRINOLOGY[J]. 2023, 第 14 作者 通讯作者 14: http://dx.doi.org/10.3389/fendo.2023.1110337.
[5] Fan Guoqing, Li Danni, Liu Jingjing, Tao Ningning, Meng Chao, Cui Ju, Cai Jianping, Sun Tieying. HNRNPD is a prognostic biomarker in non-small cell lung cancer and affects tumor growth and metastasis via the PI3K-AKT pathway. Biotechnology and Genetic Engineering Reviews[J]. 2023, 第 6 作者27: 1-20,
[6] Li, Jin, Zhang, He, Wang, ZhenHe, Li, YunXuan, Zhang, LiQun, Cui, Ju, Li, DanNi, Wang, ZiHui, Liu, Qian, Liu, Zhen, Iwakuma, Tomoo, Cai, JianPing. 8-oxo-dGTP curbs tumor development via S phase arrest and AIF-mediated apoptosis. FREE RADICAL BIOLOGY AND MEDICINE[J]. 2023, 第 6 作者196: 53-64, http://dx.doi.org/10.1016/j.freeradbiomed.2023.01.012.
[7] Sun, Shenghui, Xu, Kun, Yan, Mingjing, Cui, Ju, Zhu, Kaiyi, Yang, Yao, Zhang, Xiaoyi, Tang, Weiqing, Huang, Xiuqing, Dou, Lin, Chen, Beidong, Lin, Yajun, Zhang, Xiyue, Man, Yong, Li, Jian, Shen, Tao. Delphinidin induces autophagic flux blockage and apoptosis by inhibiting both multidrug resistance gene 1 and DEAD-box helicase 17 expressions in liver cancer cells. JOURNAL OF PHARMACY AND PHARMACOLOGY[J]. 2023, 第 4 作者75(2): 253-263, http://dx.doi.org/10.1093/jpp/rgac037.
[8] Jiang, Shan, Cui, Ju, Zhang, LiQun, Liu, Zhen, Zhang, Yan, Shi, Yuan, Cai, JianPing. Role of a Urinary Biomarker in the Common Mechanism of Physical Performance and Cognitive Function. FRONTIERS IN MEDICINE[J]. 2022, 第 2 作者9: http://dx.doi.org/10.3389/fmed.2022.816822.
[9] Liu, YuanYuan, Huo, Da, Zeng, LvTao, Fan, GuoQing, Shen, Tao, Zhang, TieMei, Cai, JianPing, Cui, Ju. Mesencephalic astrocyte-derived neurotrophic factor (MANF): Structure, functions and therapeutic potential. AGEING RESEARCH REVIEWS. 2022, 第 8 作者 通讯作者 82: http://dx.doi.org/10.1016/j.arr.2022.101763.
[10] Xu, Kun, Sun, Shenghui, Yan, Mingjing, Cui, Ju, Yang, Yao, Li, Wenlin, Huang, Xiuqing, Dou, Lin, Chen, Beidong, Tang, Weiqing, Lan, Ming, Li, Jian, Shen, Tao. DDX5 and DDX17-multifaceted proteins in the regulation of tumorigenesis and tumor progression. FRONTIERS IN ONCOLOGY. 2022, 第 4 作者12: http://dx.doi.org/10.3389/fonc.2022.943032.
[11] 陈爱群, 蔡剑平, 崔菊. IgG4相关性米库力兹综合征1例及其血浆细胞因子研究. 中华老年医学杂志[J]. 2022, 第 3 作者41(3): 335-337, http://lib.cqvip.com/Qikan/Article/Detail?id=7106906731.
[12] Weng, Qinghua, Chen, Chaojie, Xiong, Jianhua, Liu, YaNan, Pan, Xinxin, Cui, Ju, Cai, JianPing, Xu, RenAi. Effect of Baicalein on the Pharmacokinetics of Cilostazol and Its Two Metabolites in Rat Plasma Using UPLC-MS/MS Method. FRONTIERS IN PHARMACOLOGY[J]. 2022, 第 6 作者 通讯作者 13: http://dx.doi.org/10.3389/fphar.2022.888054.
[13] Zhang, He, Jiang, Pengjun, Lv, Mengyuan, Zhao, Yanhua, Cui, Ju, Chen, Jie. OGG1 contributes to hepatocellular carcinoma by promoting cell cycle-related protein expression and enhancing DNA oxidative damage repair in tumor cells. JOURNAL OF CLINICAL LABORATORY ANALYSIS[J]. 2022, 第 5 作者 通讯作者 36(7): http://dx.doi.org/10.1002/jcla.24561.
[14] Zhang, Chi, Hao, Jinjuan, Liu, Ye, Cui, Ju, Yu, Hao. Associations Between Online Learning, Smartphone Addiction Problems, and Psychological Symptoms in Chinese College Students After the COVID-19 Pandemic. FRONTIERS IN PUBLIC HEALTH[J]. 2022, 第 4 作者 通讯作者 10: http://dx.doi.org/10.3389/fpubh.2022.881074.
[15] Yuan, Lingjing, Qian, Jianchang, Li, Xiangyu, Cui, Ju, Cai, Jianping, Hu, Guoxin. Enzymatic activity on valsartan of 38 CYP2C9 variants from the Chinese population. CHEMICO-BIOLOGICAL INTERACTIONS[J]. 2022, 第 4 作者353: http://dx.doi.org/10.1016/j.cbi.2022.109799.
[16] Li, DanNi, Yang, ChengCheng, Li, Jin, Yang, QiuGeng Ou, Zeng, LvTao, Fan, GuoQing, Liu, TengHui, Tian, XinYuan, Wang, JingJing, Zhang, He, Dai, DaPeng, Cui, Ju, Cai, JianPing. The high expression of MTH1 and NUDT5 promotes tumor metastasis and indicates a poor prognosis in patients with non-small-cell lung cancer. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH[J]. 2021, 第 12 作者1868(1): http://dx.doi.org/10.1016/j.bbamcr.2020.118895.
[17] Huo, Da, Yang, Hua, Huang, JianDong, Cai, JianPing, Cui, Ju. Roles of kinesin superfamily proteins in colorectal cancer carcinogenesis. ONCOLOGY REPORTS. 2021, 第 5 作者 通讯作者 46(1): http://dx.doi.org/10.3892/or.2021.8072.
[18] Zhang, He, Zhang, LiQun, Yang, ChengCheng, Li, Jin, Tian, XinYuan, Li, DanNi, Cui, Ju, Cai, JianPing. The high expression of NUDT5 indicates poor prognosis of breast cancer by modulating AKT / Cyclin D signaling. PLOS ONE[J]. 2021, 第 7 作者16(2): https://doaj.org/article/ebdda09c9dcb41bba3000892310bf1b8.
[19] Zhang, Chi, Zeng, Ping, Tan, Joshua, Sun, Siwei, Zhao, Minghao, Cui, Ju, Zhang, Guifang, Jia, Jinzhong, Liu, Deping. Relationship of Problematic Smartphone Use, Sleep Quality, and Daytime Fatigue Among Quarantined Medical Students During the COVID-19 Pandemic. FRONTIERS IN PSYCHIATRY[J]. 2021, 第 6 作者12: http://dx.doi.org/10.3389/fpsyt.2021.755059.
[20] 霍达, 刘晶晶, 范国庆, 曾律滔, 刘媛媛, 蔡剑平, 黄建东, 崔菊. KIF5B过表达和干扰慢病毒载体的构建及对结直肠癌细胞增殖的影响. 医学研究杂志[J]. 2021, 第 8 作者 通讯作者 50(12): 43-48, http://lib.cqvip.com/Qikan/Article/Detail?id=7106257236.
[21] Yu, Xiaoxue, Ruan, Yang, Huang, Xiuqing, Dou, Lin, Lan, Ming, Cui, Ju, Chen, Beidong, Gong, Huan, Wang, Que, Yan, Mingjing, Sun, Shenghui, Qiu, Quan, Zhang, Xiyue, Man, Yong, Tang, Weiqing, Li, Jian, Shen, Tao. Dexrazoxane ameliorates doxorubicin-induced cardiotoxicity by inhibiting both apoptosis and necroptosis in cardiomyocytes. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2020, 第 6 作者523(1): 140-146, http://dx.doi.org/10.1016/j.bbrc.2019.12.027.
[22] 范国庆, 欧阳秋庚, 曾律滔, 崔菊, 奚桓, 蔡剑平. 脂联素在小鼠各脏器组织中增龄性变化的研究. 中华老年医学杂志[J]. 2020, 第 4 作者39(5): 582-586, http://lib.cqvip.com/Qikan/Article/Detail?id=7101921560.
[23] 向云青, 权菲菲, 温慧, 袁国栋, 崔菊, 黄术强. 基于仿生微流控技术的肠道器官芯片构建. 集成技术[J]. 2020, 第 5 作者 通讯作者 9(3): 56-65, http://lib.cqvip.com/Qikan/Article/Detail?id=7102046489.
[24] 曾律滔, 范国庆, 欧阳秋庚, 崔菊, 蔡剑平. LOX-1作为潜在的肺特异性衰老标志物的相关研究. 医学研究杂志[J]. 2020, 第 4 作者49(7): 22-26, http://lib.cqvip.com/Qikan/Article/Detail?id=7102380742.
[25] Zhao, Ban, Chen, Aiqun, Wang, Haitao, Cui, Ju, Sun, Ying, Xu, Lengnan, Mao, Yonghui. The relationship between sclerostin and carotid artery atherosclerosis in patients with stage 3-5 chronic kidney disease. INTERNATIONAL UROLOGY AND NEPHROLOGY[J]. 2020, 第 4 作者52(7): 1329-1336, https://www.webofscience.com/wos/woscc/full-record/WOS:000542720500017.
[26] Zhang, LiQun, Xiao, Yao, Zhou, XiaoYang, Cui, Ju, Cai, JianPing. Characterization of the novel HLA-DRB1*11:245 allele by sequencing-based typing. HLA. 2019, 第 4 作者93(2-3): 133-+,
[27] Zhang, LiQun, Xiao, Yao, Zhou, XiaoYang, Cui, Ju, Cai, JianPing. Characterization of the novel HLA-DQB1*03:01:45 allele by sequencing-based typing. HLA. 2019, 第 4 作者93(2-3): 136-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000462256400027.
[28] Lin, Raozhou, Duan, Zhigang, Sun, Haitao, Fung, ManLung, Chen, Hansen, Wang, Jing, Lau, ChiFai, Yang, Di, Liu, Yu, Ni, Yanxiang, Wang, Zai, Cui, Ju, Wu, Wutian, Yung, WingHo, Chan, YingShing, Lo, Amy C Y, Xia, Jun, Shen, Jiangang, Huang, JianDong. Kinesin-1 Regulates Extrasynaptic Targeting of NMDARs and Neuronal Vulnerability Toward Excitotoxicity. ISCIENCE[J]. 2019, 第 12 作者13: 82-+, http://dx.doi.org/10.1016/j.isci.2019.02.009.
[29] Yinghui Li, Xiangran Lu, Qianmeng Lin, Huanle Huang, Xiaolong Liang, Jianping Cai, Ju Cui, Guoxin Hu. Functional characterization of 27 CYP3A4 variants on macitentan metabolism in vitro. Journal of Pharmacy and Pharmacology[J]. 2019, 第 7 作者 通讯作者 71(11): 1677-1683, https://www.doi.org/10.1111/jphp.13153.
[30] Sun, Jingyu, Zhang, Yang, Zhen, Yongzhan, Cui, Ju, Hu, Gang, Lin, Yajun. Antitumor activity of tetrandrine citrate in human glioma U87 cells in vitro and in vivo. ONCOLOGY REPORTS[J]. 2019, 第 4 作者42(6): 2345-2354,
[31] Liu, Tong, Cai, JianPing, Zhang, LiQun, Sun, Ning, Cui, Ju, Wang, Hua, Yang, JieFu. The mechanism of RNA oxidation involved in the development of heart failure. FREE RADICAL RESEARCH[J]. 2019, 第 5 作者53(8): 910-921, http://dx.doi.org/10.1080/10715762.2019.1646424.
[32] Liu, Jiang, Zhen, YongZhan, Cui, Ju, Hu, Gang, Wei, Jie, Xu, Rong, Tu, Ping, Lin, YaJun. Dynamic influence of Rhein lysinate on HeLa cells. INTERNATIONAL JOURNAL OF ONCOLOGY[J]. 2018, 第 3 作者53(5): 2047-2055, https://www.webofscience.com/wos/woscc/full-record/WOS:000447703300018.
[33] Pang, Jing, Cui, Ju, Xi, Chao, Shen, Tao, Gong, Huan, Dou, Lin, Lin, Yajun, Zhang, Tiemei. Inhibition of Poly(ADP-Ribose) Polymerase Increased Lipid Accumulation Through SREBP1 Modulation. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY[J]. 2018, 第 2 作者49(2): 645-652, https://doaj.org/article/038718dd19d34cf69d14b0590a18b33c.
[34] Chen, Aiqun, Sun, Ying, Cui, Ju, Zhao, Ban, Wang, Haitao, Chen, Xianguang, Mao, Yonghui. Associations of sclerostin with carotid artery atherosclerosis and all-cause mortality in Chinese patients undergoing maintenance hemodialysis. BMC NEPHROLOGY[J]. 2018, 第 3 作者19(1): https://doaj.org/article/1d4360f2263c4474a6d3ad53ad909c2b.
[35] Cui, Ju, Pang, Jing, Lin, YaJun, Gong, Huan, Wang, ZhenHe, Li, YunXuan, Li, Jin, Wang, Zai, Jiang, Ping, Dai, DaPeng, Li, Jian, Cai, JianPing, Huang, JianDong, Zhang, TieMei. Adipose-specific deletion of Kif5b exacerbates obesity and insulin resistance in a mouse model of diet-induced obesity. FASEB JOURNAL[J]. 2017, 第 1 作者31(6): 2533-2547,
[36] 崔菊, 陈爱群, 庞婧, 李瑾, 李云炫, 张铁梅, 蔡剑平. 高脂饮食影响小鼠体内能量代谢的性别差异. 山西医科大学学报[J]. 2017, 第 1 作者48(7): 658-664, http://lib.cqvip.com/Qikan/Article/Detail?id=672836688.
[37] Li, Jin, Yang, ChengCheng, Tian, XinYuan, Li, YunXuan, Cui, Ju, Chen, Zhe, Deng, ZhouLu, Chen, FuJun, Hayakawa, Hiroshi, Sekiguchi, Mutsuo, Cai, JianPing. MutT-related proteins are novel progression and prognostic markers for colorectal cancer. ONCOTARGET[J]. 2017, 第 5 作者8(62): 105714-105726, http://dx.doi.org/10.18632/oncotarget.22393.
[38] 崔菊. 驱动蛋白-1在小鼠脂肪组织糖脂代谢中的作用研究. 现代生物医学进展. 2017, 第 1 作者
[39] 崔菊, 庞静, 宫环, 蔡剑平, 张铁梅. GLUT4和脂联素在3T3-L1脂肪细胞中共享囊泡转运机制. 医学研究杂志[J]. 2017, 第 1 作者46(3): 18-21, http://lib.cqvip.com/Qikan/Article/Detail?id=671719552.
[40] Wei, Jie, Zhen, YongZhan, Cui, Ju, He, FaLin, Shen, Tao, Hu, Gang, Ren, XiaoHong, Lin, YaJun. Rhein lysinate decreases inflammation and adipose infiltration in KK/HlJ diabetic mice with non-alcoholic fatty liver disease. ARCHIVES OF PHARMACAL RESEARCH[J]. 2016, 第 3 作者39(7): 960-969, https://www.webofscience.com/wos/woscc/full-record/WOS:000379692900010.
[41] Pang, Jing, Xi, Chao, Huang, Xiuqing, Cui, Ju, Gong, Huan, Zhang, Tiemei. Effects of Excess Energy Intake on Glucose and Lipid Metabolism in C57BL/6 Mice. PLOS ONE[J]. 2016, 第 4 作者11(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000367815600075.
[42] Cui Ju. Conventional kinesin KIF5B mediates adiponectin secretion in 3T3-L1 adipocyte. Biochem Biophys Res Commun. 2016, 第 1 作者
[43] 崔菊, 金国祥, 雷霆, 王在, 黄建东, 蔡剑平. 沉默Kif5b赋予MDCK细胞干性. 医学研究杂志[J]. 2016, 第 1 作者45(5): 58-62, http://lib.cqvip.com/Qikan/Article/Detail?id=668934986.
[44] Cui, Ju, Jin, Guoxiang, Yu, Bin, Wang, Zai, Lin, Raozhou, Huang, JianDong. Stable knockdown of Kif5b in MDCK cells leads to epithelial-mesenchymal transition. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2015, 第 1 作者 通讯作者 463(1-2): 123-129, https://www.webofscience.com/wos/woscc/full-record/WOS:000356753400021.
[45] Pang, Jing, Cui, Ju, Gong, Huan, Xi, Chao, Zhang, Tiemei. Effect of NAD on PARP-Mediated Insulin Sensitivity in Oleic Acid Treated Hepatocytes. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2015, 第 2 作者230(7): 1607-1613, https://www.webofscience.com/wos/woscc/full-record/WOS:000351842500021.
[46] Cui, Ju, Li, Xiuling, Duan, Zhigang, Xue, Wenqian, Wang, Zai, Lu, Song, Lin, Raozhou, Liu, Mengfei, Zhu, Guixia, Huang, JianDong. Analysis of Kif5b Expression during Mouse Kidney Development. PLOSONE[J]. 2015, 第 1 作者 通讯作者 10(4): https://doaj.org/article/2268a5e7e82048edb4c6c12d22e4bdb8.
[47] Jiandong Huang, Zai Wang, Ju Cui, Wutian Wu. Molecular motor protein kinesin-1 controls the localization of mitochondria and myofibrils components. BBA - BIOENERGETICS. 2014, 第 3 作者1837: e27-e27, http://dx.doi.org/10.1016/j.bbabio.2014.05.297.
[48] Cui, Ju, Wu, Long Tao, Chu, Ka Hou. Comparative proteomic profiling during ovarian development of the shrimp Metapenaeus ensis. MOLECULAR BIOLOGY REPORTS[J]. 2014, 第 1 作者 通讯作者 41(1): 519-528, https://www.webofscience.com/wos/woscc/full-record/WOS:000329100500056.
[49] Cui, Ju, Wu, Longtao, Chan, SiuMing, Chu, Ka Hou. cDNA cloning and mRNA expression of retinoid-X-receptor in the ovary of the shrimp Metapenaeus ensis. MOLECULAR BIOLOGY REPORTS[J]. 2013, 第 1 作者40(11): 6233-6244, https://www.webofscience.com/wos/woscc/full-record/WOS:000325948900020.
[50] Wang, Zai, Cui, Ju, Wong, Wai Man, Li, Xiuling, Xue, Wenqian, Lin, Raozhou, Wang, Jing, Wang, Peigang, Tanner, Julian A, Cheah, Kathryn S E, Wu, Wutian, Huang, JianDong. Kif5b controls the localization of myofibril components for their assembly and linkage to the myotendinous junctions. DEVELOPMENT[J]. 2013, 第 2 作者140(3): 617-626, https://www.webofscience.com/wos/woscc/full-record/WOS:000313363500015.
[51] Cui, Ju, Wang, Zai, Cheng, Qianni, Lin, Raozhou, Zhang, XinMei, Leung, Po Sing, Copeland, Neal G, Jenkins, Nancy A, Yao, KwokMing, Huang, JianDong. Targeted Inactivation of Kinesin-1 in Pancreatic beta-Cells In Vivo Leads to Insulin Secretory Deficiency. DIABETES[J]. 2011, 第 1 作者60(1): 320-330, https://www.webofscience.com/wos/woscc/full-record/WOS:000286017300039.
科研活动
科研项目
（ 1 ） 我国人群增龄过程中健康状态变化特点与规律的研究, 参与, 国家任务, 2018-12--2022-12
（ 2 ） 亚健康状态的多参数量化评价研究, 负责人, 国家任务, 2020-01--2023-12
（ 3 ） 马达蛋白KIF5B在结直肠癌发生发展中的作用及机制研究, 负责人, 研究所自主部署, 2016-07--2019-06
（ 4 ） 马达蛋白Kinesin-1调节脂联素分泌的作用及机制研究, 负责人, 国家任务, 2015-01--2017-12
（ 5 ） Kinesin-1调节脂联素分泌的作用及机制研究, 负责人, 地方任务, 2015-01--2016-12
（ 6 ） 马达蛋白KIF5B在结直肠癌浸润和转移中的作用及机制研究, 负责人, 国家任务, 2021-01--2024-12
（ 7 ） 抗衰老关键细胞因子组合筛选及合成生物学调控, 负责人, 研究所自主部署, 2022-01--2022-12
（ 8 ） 马达蛋白KIF7介导的SHH信号通路调控皮下脂肪衰老的作用及机制研究, 负责人, 地方任务, 2023-01--2023-12
（ 9 ） 衰老的关键分子机制及衰老标志物的研究, 负责人, 地方任务, 2021-10--2025-12
（ 2 ） 亚健康状态的多参数量化评价研究, 负责人, 国家任务, 2020-01--2023-12
（ 3 ） 马达蛋白KIF5B在结直肠癌发生发展中的作用及机制研究, 负责人, 研究所自主部署, 2016-07--2019-06
（ 4 ） 马达蛋白Kinesin-1调节脂联素分泌的作用及机制研究, 负责人, 国家任务, 2015-01--2017-12
（ 5 ） Kinesin-1调节脂联素分泌的作用及机制研究, 负责人, 地方任务, 2015-01--2016-12
（ 6 ） 马达蛋白KIF5B在结直肠癌浸润和转移中的作用及机制研究, 负责人, 国家任务, 2021-01--2024-12
（ 7 ） 抗衰老关键细胞因子组合筛选及合成生物学调控, 负责人, 研究所自主部署, 2022-01--2022-12
（ 8 ） 马达蛋白KIF7介导的SHH信号通路调控皮下脂肪衰老的作用及机制研究, 负责人, 地方任务, 2023-01--2023-12
（ 9 ） 衰老的关键分子机制及衰老标志物的研究, 负责人, 地方任务, 2021-10--2025-12
参与会议
（1）Low expression NUDT5 induces cellular dysfunction in breast cancer cell lines 2019年美国细胞生物学年会 2018-12-08
（2）KIF5B deficiency exacerbates the deleterious effect of high-fat diet on body weight and metabolism 2016年全国老年基础与转化医学力论坛 2016-11-04
（2）KIF5B deficiency exacerbates the deleterious effect of high-fat diet on body weight and metabolism 2016年全国老年基础与转化医学力论坛 2016-11-04