基本信息
蔡小青  男  硕导  中国科学院上海应用物理研究所
电子邮件: caixq@sari.ac.cn
通信地址: 上海市嘉定区嘉罗公路2019号
邮政编码: 201800

招生信息

   
招生专业
070301-无机化学
071011-生物物理学
招生方向
同步辐射成像探针研制及应用;同步辐射脑成像

教育背景

2003-09--2008-06   中国科学院大学   博士学位
学历
博士

学位
研究生

专利与奖励

   
专利成果
( 1 ) 一种用于人脑组织成像的同步辐射X射线成像染色方法, 发明专利, 2023, 第 3 作者, 专利号: CN116429544A

( 2 ) 一种同步X射线可见的点击化学成像标签及其制备方法, 发明专利, 2023, 第 4 作者, 专利号: CN202310182738

( 3 ) 一种基于同步光源的X射线点击化学标记探针及其制备方法以及应用, 发明专利, 2023, 第 1 作者, 专利号: CN116465915A

( 4 ) 一种用于大尺寸脑组织的高效的高尔基染色方法, 发明专利, 2021, 第 2 作者, 专利号: CN113281130A

( 5 ) 富勒醇在美容护肤品中的应用, 发明专利, 2011, 第 2 作者, 专利号: CN101239026B

( 6 ) C 60 的多羟基衍生物在防治线粒体损伤相关疾病中的用途, 发明专利, 2009, 第 2 作者, 专利号: CN101396372A

( 7 ) C 60 的衍生物富勒醇在滋养毛发方面的应用, 发明专利, 2007, 第 2 作者, 专利号: CN1296054

( 8 ) 一种用于原代神经元细胞的高尔基染色方法及其应用, 发明专利, 2024, 第 1 作者, 专利号: 202410682399.X

出版信息

   
发表论文
[1] 周峰, 蔡小青, 汤乔伟, 诸颖, 王丽华, 胡钧. 银染高尔基染色法用于神经元完整结构成像. 应用化学[J]. 2024, 第 2 作者  通讯作者  41(5): 677-686, 
[2] Qiaowei Tang, Dapeng Yin, Yubo Liu, Jichao Zhang, Yong Guan, Huating Kong, Yiliu Wang, Xiangzhi Zhang, Jiang Li, Lihua Wang, Jun Hu, Xiaoqing Cai, Ying Zhu. Clickable X‑ray Nanoprobes for Nanoscopic Bioimaging of Cellular Structures. JACS Au[J]. 2024, 第 12 作者  通讯作者  4: 893-902, 
[3] Liu, Zhichao, Zhu, Ying, Zhang, Liming, Jiang, Weiping, Liu, Yawei, Tang, Qiaowei, Cai, Xiaoqing, Li, Jiang, Wang, Lihua, Tao, Changlu, Yin, Xianzhen, Li, Xiaowei, Hou, Shangguo, Jiang, Dawei, Liu, Kai, Zhou, Xin, Zhang, Hongjie, Liu, Maili, Fan, Chunhai, Tian, Yang. Structural and functional imaging of brains. SCIENCE CHINA-CHEMISTRY. 2023, 第 7 作者66(2): 324-366, http://lib.cqvip.com/Qikan/Article/Detail?id=7109033570.
[4] Tang Qiaowei, Cai Xiaoqing, Yin Dapeng, Kong Huating, Zhang Xiangzhi, Zhang Jichao, Yan Qinglong, Zhu Ying, Fan Chunhai. Click Chemistry-based Synchrotron X-ray Imaging Tags. ACTA CHIMICA SINICA[J]. 2023, 第 2 作者81(5): 441-444, http://dx.doi.org/10.6023/A23030061.
[5] 诸颖, 蔡小青, 张瑜, 张继超, 殷大鹏, 汤乔伟, 王丽华, 樊春海. 同步辐射技术在生物成像分析中的应用. 中国科学. 化学[J]. 2023, 第 2 作者53(11): 2196-2207, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7623576&detailType=1.
[6] Tang, Qiaowei, Cai, Xiaoqing, Li, Jiang, Zhu, Ying, Wang, Lihua, Tian, Yang, Fan, Chunhai, Hu, Jun. Synchrotron-based X-ray Microscopy for Brain Imaging. CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE[J]. 2022, 第 2 作者  通讯作者  43(12): 
[7] 燕鑫, 蔡小青, 汤乔伟, 周峰, 诸颖, 王丽华, 胡钧. 应用同步辐射X射线多模态成像研究死亡延迟时间对脑组织染色的影响. 核技术[J]. 2022, 第 2 作者  通讯作者  45(4): 17-23, http://lib.cqvip.com/Qikan/Article/Detail?id=7107008913.
[8] Chen, Hsiang Hsin, Yang, ShunMin, Yang, KaiEn, Chiu, ChingYu, Chang, ChiaJu, Wang, YaSian, Lee, TsungTse, Huang, YuFen, Chen, YiYun, Petibois, Cyril, Chang, ShihHung, Cai, Xiaoqing, Low, ChianMing, Tan, Francis Chee Kuan, Teo, Alvin, Tok, Eng Soon, Lim, JaeHong, Je, JunHo, Kohmura, Yoshiki, Ishikawa, Tetsuya, Margaritondo, Giorgio, Hwu, Yeukuang. High-resolution fast-tomography brain-imaging beamline at the Taiwan Photon Source. JOURNAL OF SYNCHROTRON RADIATION. 2021, 第 12 作者28: 1662-1668, http://dx.doi.org/10.1107/S1600577521007633.
[9] Chin, AnLun, Yang, ShunMin, Chen, HsiangHsin, Li, MinTsang, Lee, TsungTse, Chen, YingJie, Lee, TingKuo, Petibois, Cyril, Cai, Xiaoqing, Low, ChianMing, Tan, Francis Chee Kuan, Teo, Alvin, Tok, Eng Soon, Ong, Edwin B L, Lin, YenYin, Lin, IJin, Tseng, YiChi, Chen, NanYow, Shih, ChiTin, Lim, JaeHong, Lim, Jun, Je, JungHo, Kohmura, Yoshiki, Ishikawa, Tetsuya, Margaritondo, Giorgio, Chiang, AnnShyn, Hwu, Yeukuang. A synchrotron X-ray imaging strategy to map large animal brains. CHINESE JOURNAL OF PHYSICS[J]. 2020, 第 9 作者65: 24-32, http://dx.doi.org/10.1016/j.cjph.2020.01.010.
[10] Wang, Shaopeng, Deng, Suhui, Cai, Xiaoqing, Hou, Shangguo, Li, Jiajun, Gao, Zhaoshuai, Li, Jiang, Wang, Lihua, Fan, Chunhai. Superresolution imaging of telomeres with continuous wave stimulated emission depletion (STED) microscope. SCIENCE CHINA-CHEMISTRY[J]. 2016, 第 3 作者59(11): 1519-1524, http://ir.sinap.ac.cn/handle/331007/26640.
[11] Wang, Shaopeng, Cai, Xiaoqing, Wang, Lihua, Li, Jiang, Li, Qian, Zuo, Xiaolei, Shi, Jiye, Huang, Qing, Fan, Chunhai. DNA orientation-specific adhesion and patterning of living mammalian cells on self-assembled DNA monolayers. CHEMICAL SCIENCE[J]. 2016, 第 2 作者7(4): 2722-2727, http://ir.sinap.ac.cn/handle/331007/25690.
[12] Zhu, Ying, Earnest, Thomas, Huang, Qing, Cai, Xiaoqing, Wang, Zhili, Wu, Ziyu, Fan, Chunhai. Synchrotron-Based X-Ray-Sensitive Nanoprobes for Cellular Imaging. ADVANCED MATERIALS[J]. 2014, 第 4 作者26(46): 7889-7895, http://dx.doi.org/10.1002/adma.201304281.
[13] Zhu, Ying, Cai, Xiaoqing, Li, Jiang, Zhong, Zengtao, Huang, Qing, Fan, Chunhai. Synchrotron-based X-ray microscopic studies for bioeffects of nanomaterials. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. 2014, 第 2 作者10(3): 515-524, http://dx.doi.org/10.1016/j.nano.2013.11.005.
[14] Zhang, Jichao, Li, Bo, Zhang, Yi, Li, Aiguo, Yu, Xiaohan, Huang, Qing, Fana, Chunhai, Cai, Xiaoqing. Synchrotron radiation X-ray fluorescence analysis of biodistribution and pulmonary toxicity of nanoscale titanium dioxide in mice. ANALYST[J]. 2013, 第 8 作者138(21): 6511-6516, http://dx.doi.org/10.1039/c3an01267k.
[15] 张一, 张继超, 诸颖, 孙艳红, 王坤, 樊春海, 黄庆, 蔡小青. 同步辐射X射线显微成像技术在细胞生物学中的应用. 生命科学[J]. 2013, 第 8 作者  通讯作者  25(8): 754-761, http://ir.sinap.ac.cn/handle/331007/13563.
[16] Zhang, Jichao, Cai, Xiaoqing, Zhang, Yi, Li, Xiaoming, Li, Wenxin, Tian, Yangchao, Li, Aiguo, Yu, Xiaohan, Fan, Chunhai, Huang, Qing. Imaging cellular uptake and intracellular distribution of TiO2 nanoparticles. ANALYTICAL METHODS[J]. 2013, 第 2 作者  通讯作者  5(23): 6611-6616, http://dx.doi.org/10.1039/c3ay41121d.
[17] ChiaChi Chien, HsiangHsin Chen, ShengFeng Lai, KangChao Wu, Xiaoqing Cai, Yeukuang Hwu, Cyril Petibois, Yong Chu, Giorgio Margaritondo. Gold nanoparticles as high-resolution X-ray imaging contrast agents for the analysis of tumor-related micro-vasculature. JOURNAL OF NANOBIOTECHNOLOGY,10,1(2012-03-12)[J]. 2012, 第 5 作者10(1): http://gooa.las.ac.cn/external/index?type=-1&pid=806660.
[18] Chen, HsiangHsin, Chien, ChiaChi, Petibois, Cyril, Wang, ChengLiang, Chu, Yong S, Lai, ShengFeng, Hua, TzuEn, Chen, YiYun, Cai, Xiaoqing, Kempson, Ivan M, Hwu, Yeukuang, Margaritondo, Giorgio. Quantitative analysis of nanoparticle internalization in mammalian cells by high resolution X-ray microscopy. JOURNAL OF NANOBIOTECHNOLOGY[J]. 2011, 第 9 作者9(1): 14-14, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201706301432758ZK.
[19] Cai, Xiaoqing, Chen, HsiangHsin, Wang, ChengLiang, Chen, ShinTai, Lai, ShengFeng, Chien, ChiaChi, Chen, YiYun, Kempson, Ivan M, Hwu, Yeukuang, Yang, C S, Margaritondo, G. Imaging the cellular uptake of tiopronin-modified gold nanoparticles. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2011, 第 1 作者401(3): 809-816, https://www.webofscience.com/wos/woscc/full-record/WOS:000292970200005.
[20] Lai, ShengFeng, Chen, WenChang, Wang, ChengLiang, Chen, HsiangHsin, Chen, ShinTai, Chien, ChiaChi, Chen, YiYun, Hung, WenTing, Cai, Xiaoqing, Li, Enrong, Kempson, Ivan M, Hwu, Y, Yang, C S, Tok, EngSoon, Tan, Hui Ru, Lin, Ming, Margaritondo, G. One-Pot Tuning of Au Nucleation and Growth: From Nanoclusters to Nanoparticles. LANGMUIR[J]. 2011, 第 9 作者27(13): 8424-8429, https://www.webofscience.com/wos/woscc/full-record/WOS:000292124000059.
[21] Wang, ChengLiang, Hsao, BoJun, Lai, ShengFeng, Chen, WenChang, Chen, HsiangHsin, Chen, YiYun, Chien, ChiaChi, Cai, Xiaoqing, Kempson, Ivan M, Hwu, Y, Margaritondo, G. One-pot synthesis of AuPt alloyed nanoparticles by intense x-ray irradiation. NANOTECHNOLOGY[J]. 2011, 第 8 作者22(6): https://www.webofscience.com/wos/woscc/full-record/WOS:000285998900015.
[22] Cai, Xiaoqing, Wang, ChengLiang, Chen, HsiangHsin, Chien, ChiaChi, Lai, ShengFeng, Chen, YiYun, Hua, TzuEn, Kempson, Ivan M, Hwu, Y, Yang, C S, Margaritondo, G. Tailored Au nanorods: optimizing functionality, controlling the aspect ratio and increasing biocompatibility. NANOTECHNOLOGY[J]. 2010, 第 1 作者21(33): https://www.webofscience.com/wos/woscc/full-record/WOS:000280383500012.
[23] Cai, Xiaoqing, Hao, Jiejie, Zhang, Xiaoyong, Yu, Bozhang, Ren, Jinming, Luo, Cheng, Li, Qingnuan, Huang, Qing, Shi, Xianglin, Li, Wenxin, Liu, Jiankang. The polyhydroxylated fullerene derivative C-60(OH)(24) protects mice from ionizing-radiation-induced immune and mitochondrial dysfunction. TOXICOLOGY AND APPLIED PHARMACOLOGY[J]. 2010, 第 1 作者243(1): 27-34, https://www.webofscience.com/wos/woscc/full-record/WOS:000274489700004.
[24] Liu, Ruili, Cai, Xiaoqing, Wang, Jiandong, Li, Jungang, Huang, Qing, Li, Wenxin. Research on the Bioactivities of C-60-Dexamethasone. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY[J]. 2009, 第 2 作者9(5): 3171-3176, http://www.corc.org.cn/handle/1471x/2404272.
[25] 蔡小青, 李文新, 刘瑞丽, 李晴暖, 黄庆. 富勒醇的生物活性及其在护理产品研发巾的应用. 中国科技成果[J]. 2008, 第 1 作者60-60, http://lib.cqvip.com/Qikan/Article/Detail?id=29092208.
[26] Cai, Xiaoqing, Jia, Haiqun, Liu, Zhongbo, Hou, Bei, Luo, Cheng, Feng, Zhihui, Li, Wenxin, Liu, Jiankang. Polyhydroxylated Fullerene Derivative C-60(OH)(24) Prevents Mitochondrial Dysfunction and Oxidative Damage in an MPP+-Induced Cellular Model of Parkinson's Disease. JOURNAL OF NEUROSCIENCE RESEARCH[J]. 2008, 第 1 作者86(16): 3622-3634, http://www.corc.org.cn/handle/1471x/2389008.
[27] Li, Jungang, Li, Qingnuan, Xu, Jingying, Li, Jing, Cai, Xiaoqing, Liu, Ruili, Li, Yongjun, Ma, Jifei, Li, Wenxin. Comparative study on the acute pulmonary toxicity induced by 3 and 20 nm TiO2 primary particles in mice. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY[J]. 2007, 第 5 作者24(3): 239-244, http://dx.doi.org/10.1016/j.etap.2007.06.004.
[28] 诸颖, 赵群芬, 蔡小青, 李宇国, 李文新. 碳纳米管(CNTs)与贻贝棘尾虫的相互作用研究. 核技术[J]. 2006, 第 3 作者29(3): 202-206, http://lib.cqvip.com/Qikan/Article/Detail?id=21393849.
[29] 蔡小青, 李宇国, 吴胜伟, 叶波, 冉铁成, 郭金学, 徐慧, 李文斯. 富勒醇对^60Coγ射线致小鼠损伤的防护作用. 中华放射医学与防护杂志[J]. 2004, 第 1 作者24(6): 520-522, http://lib.cqvip.com/Qikan/Article/Detail?id=15210858.