基本信息
周兵 男 博导 中国科学院动物研究所
电子邮件: zhoubing@ioz.ac.cn
通信地址: 北京市朝阳区北辰西路1号院5号
邮政编码: 100101
电子邮件: zhoubing@ioz.ac.cn
通信地址: 北京市朝阳区北辰西路1号院5号
邮政编码: 100101
研究领域
课题组研究领域主要聚焦多细胞互作微环境中细胞的身份决定与维持、细胞间协作和组织、器官衰老与再生等科学问题,运用计算生物学与大规模高通量实验技术相结合的方法,从功能基因组学、表观遗传学、染色质高级结构以及单细胞生物学等多个生物学层面,系统性地阐释多细胞微环境的性质、功能与分子调控机制。
招生信息
招生专业
0710Z1-基因组学0710J3-生物信息学071010-生物化学与分子生物学
招生方向
基因组学,生物信息学,计算生物学发育生物学,干细胞,细胞微环境
教育背景
2006-09--2012-06 中国科学院遗传与发育生物学研究所 生物信息学博士2000-09--2004-06 湖南大学 管理学学士
工作经历
工作简历
2018-06~现在, 中国科学院动物研究所, 研究员2014-05~2018-06,美国加州大学圣地亚哥分校, 博士后2012-07~2014-04,中国科学院遗传与发育生物学研究所, 博士后2004-07~2006-02,中国工商银行软件开发中心, 软件工程师
社会兼职
2019-09-01-2024-08-31,中国科学技术大学博士生导师, 博士生导师
教授课程
实用生物信息学(2):多组学数据整合与深度挖掘
出版信息
发表论文
(1) Remodeling of maternal mRNA through poly(A) tail orchestrates human oocyte-to-embryo transition, NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2023, 通讯作者(2) Comprehensive optimization of a reporter assay toolbox for three distinct CRISPR-Cas systems, FEBS OPEN BIO, 2021, 通讯作者(3) GRID-seq for comprehensive analysis of global RNA-chromatin interactions, NATURE PROTOCOLS, 2019, 第 1 作者(4) The Polycomb Repressor Complex 1 Drives Double Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression, CANCER CELL, 2019, 第 5 作者(5) The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor, NATURE COMMUNICATIONS, 2019, 第11作者(6) The Histone H3K4 Demethylase JMJ16 Represses Leaf Senescence in Arabidopsis, THE PLANT CELL, 2019, 第 3 作者(7) The Histone H3K4 Demethylase JMJ16 Represses Leaf Senescence in Arabidopsis, PLANT CELL, 2019, 第 3 作者(8) A novel class of microrna-recognition elements that function only within open reading frames, NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2018, 第 14 作者(9) Allele-specific mechanisms of activation of MEK1 mutants determine their properties, CANCER DISCOVERY, 2018, 第 5 作者(10) GRID-seq reveals the global RNA-chromatin interactome, NATURE BIOTECHNOLOGY, 2017, 第 2 作者(11) REF6 recognizes a specific DNA sequence to demethylate H3K27me3 and regulate organ boundary formation in Arabidopsis, NATURE GENETICS, 2016, 第 4 作者(12) Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators, RNA, 2016, 第 2 作者(13) Sequential Regulatory Loops as Key Gatekeepers for Neuronal Reprogramming in Human Cells, NATURE NEUROSCIENCE, 2016, 第 4 作者(14) RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2Targeting in Mammalian Genomes, MOLECULAR CELL, 2016, 第 8 作者(15) CELF RNA binding proteins promote axon regeneration in C. elegans and mammals through alternative splicing of Syntaxins, ELIFE,5,(2016-06-01), 2016, 第 8 作者(16) 3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors, CELL STEM CELL, 2016, 第 7 作者(17) C-terminal domains of histone demethylase JMJ14 interact with a pair of NAC transcription factors to mediate specific chromatin association, CELL DISCOVERY, 2015, 第 2 作者(18) Advanced Applications of RNA Sequencing and Challenges, BIOINFORMATICS AND BIOLOGY INSIGHTS, 2015, 第 5 作者(19) Transcriptome and Network Changes in Climbers at Extreme Altitudes, PLOS ONE, 2012, 第 9 作者(20) Midlife gene expressions identify modulators of aging through dietary interventions, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 第 1 作者(21) Genome-wide mapping of SMAD target genes reveals the role of BMP signaling in embryonic stem cell fate determination, GENOME RESEARCH, 2010, 第 4 作者(22) Inferring causal relationships among different histone modifications and gene expression, GENOME RESEARCH, 2008, 第 3 作者(23) Comparing the biological coherence of network clusters identified by different detection algorithms, CHINESE SCIENCE BULLETIN, 2007, 第 2 作者