Dr. Fan Wu & Prof. Dr. Dr. Thomas Braun

Research Areas

Epigenetic regulation on lung pathogenesis; Metabolism and Epigenetic crosstalk on lung diseases; Cell Lineage Research on Human lung diseases

Education

2006-2011 Harbin Medical University, China, BS

2012-2014 The University of Hong Kong, China, MS

2014-2021 Max Planck Institute for Heart and Lung Research, PhD

2021-2026 Max Planck Institute for Heart and Lung Research, Postdoc

Publications

Wu, F., Li, X., Looso, M., Liu, H., Ding, D., Gunther, S.,

Kuenne, C., Liu, S., Weissmann, N., Boettger, T., et al. (2023).

Spurious transcription causing innate immune responses is prevented by

5-hydroxymethylcytosine. Nat Genet 55, 100-111. 10.1038/s41588-022-01252-3.

 


Li, X., Wu, F., Gunther, S., Looso, M., Kuenne,

C., Zhang, T., Wiesnet, M., Klatt, S., Zukunft, S., Fleming, I., et al. (2023).

Inhibition of fatty acid oxidation enables heart regeneration in adult mice. Nature 622,

619-626. 10.1038/s41586-023-06585-5.

 


Wang, L., Rice, M., Swist, S., Kubin, T., Wu, F.,

Wang, S., Kraut, S., Weissmann, N., Bottger, T., Wheeler, M., et al. (2021).

BMP9 and BMP10 Act Directly on Vascular Smooth Muscle Cells for Generation and

Maintenance of the Contractile State. Circulation 143, 1394-1410.

10.1161/CIRCULATIONAHA.120.047375.

 


Yuan, X., Qi, H., Li, X., Wu, F., Fang, J.,

Bober, E., Dobreva, G., Zhou, Y., and Braun, T. (2017). Disruption of

spatiotemporal hypoxic signaling causes congenital heart disease in mice. J

Clin Invest 127, 2235-2248. 10.1172/JCI88725.

Conferences

Selection:


International Symposium 2017 "Chromatin Changes in Differentiation

and Malignancies" September 18- 20, 2017 Egmond aan Zee, The Netherlands

–poster

Summer School on Chromatin and Metabolism, August 25-31, 2018, Spetses

Island, Greece –poster


11th TRR81 Mini-symposium on "Epigenetics &

Metabolism", November 28th, 2018, Bad Nauheim, Germany –

organizer

EMBL Conference "Chromatin and Epigenetics", May 17-20, 2021,

Virtual – poster


Cellular Heterogeneity in the Cardio-Pulmonary System Symposium,

September 2021- speaker


13th Guangzhou International Forum on Stem Cells and

Regenerative Medicine 2023 - speaker


Cold Spring Harbor Chromatin, Epigenetics & Transcription, 2026, Suzhou, China

poster - best poster prize


Collaboration

Cardio Pulmonary Institute (CPI), Germany


Deutsches Zentrum für Herz-Kreislauf-Forschung E.V. (DZHK), Germany