基本信息
边少荃 男 中国科学院深圳先进技术研究院
电子邮件： sq.bian@siat.ac.cn
通信地址： 广东省深圳市南山区西丽大学城学苑大道1068号
邮政编码：
电子邮件： sq.bian@siat.ac.cn
通信地址： 广东省深圳市南山区西丽大学城学苑大道1068号
邮政编码：
研究领域
生物医学工程
生物医用高分子
水凝胶
生物3D打印
皮肤损伤修复
招生信息
招生专业
070305-高分子化学与物理
085600-材料与化工
0703Z1-化学生物学
085600-材料与化工
0703Z1-化学生物学
招生方向
生物医学工程，生物医用材料
生物医学工程，生物医用材料
生物医学工程，生物医用材料
生物医学工程，生物医用材料
生物医学工程，生物医用材料
教育背景
2013-09--2017-06 四川大学 博士
2010-09--2013-06 四川大学 硕士
2006-09--2010-06 四川大学 学士
2010-09--2013-06 四川大学 硕士
2006-09--2010-06 四川大学 学士
工作经历
工作简历
2023-01~2023-07,中国科学院深圳先进技术研究院, 副研究员
2019-10~2023-01,中国科学院深圳先进技术研究院, 助理研究员
2017-08~2019-10,中国科学院深圳先进技术研究院, 博士后
2019-10~2023-01,中国科学院深圳先进技术研究院, 助理研究员
2017-08~2019-10,中国科学院深圳先进技术研究院, 博士后
专利与奖励
专利成果
（ 1 ） 一种温敏水凝胶的制备方法及温敏水凝胶, 发明专利, 2021, 第 3 作者, 专利号: CN113842493A
（ 2 ） 基于海洋源明胶的可注射水凝胶止血剂及应用和应用方法, 发明专利, 2021, 第 2 作者, 专利号: CN111632189B
（ 3 ） 一种巯基/二硫键可控自交联透明质酸水凝胶的制备方法及其应用, 2017, 第 3 作者, 专利号: CN104892962B
（ 2 ） 基于海洋源明胶的可注射水凝胶止血剂及应用和应用方法, 发明专利, 2021, 第 2 作者, 专利号: CN111632189B
（ 3 ） 一种巯基/二硫键可控自交联透明质酸水凝胶的制备方法及其应用, 2017, 第 3 作者, 专利号: CN104892962B
出版信息
发表论文
[1] Hao Chang, Pengfei Tian, Liuzhi Hao, Chengwei Hu, Bo Liu, Fengzhen Meng, Xin Yi, Xiaohua Pan, Xiaohua Hu, Huan Wang, Xinyun Zhai, Xu Cui, Jason Pui Yin Cheung, Xuanyong Liu, Haobo Pan, Shaoquan Bian, Xiaoli Zhao. Antioxidative bioactive glass reinforced injectable hydrogel with reactive oxygen species scavenging capacity for diabetic wounds treatment. CHEMICAL ENGINEERING JOURNAL. 2024, 第 16 作者 通讯作者 481: http://dx.doi.org/10.1016/j.cej.2024.148768.
[2] Sun, Yong, Li, Xing, Zhao, Mingda, Chen, Yafang, Xu, Yang, Wang, Kefeng, Bian, Shaoquan, Jiang, Qing, Fan, Yujiang, Zhang, Xingdong. Bioinspired supramolecular nanofiber hydrogel through self-assembly of biphenyl-tripeptide for tissue engineering. BIOACTIVE MATERIALS[J]. 2022, 第 7 作者 通讯作者 8: 396-408, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7289678&detailType=1.
[3] Bian, Shaoquan, Hao, Liuzhi, Qiu, Xin, Wu, Jun, Chang, Hao, Kuang, GuanMing, Zhang, Sheng, Hu, Xiaohua, Dai, Yakang, Zhou, Zhiyong, Huang, Fangli, Liu, Chun, Zou, Xuenong, Liu, Wenguang, Lu, Willima W, Pan, Haobo, Zhao, Xiaoli. An Injectable Rapid-Adhesion and Anti-Swelling Adhesive Hydrogel for Hemostasis and Wound Sealing. ADVANCED FUNCTIONAL MATERIALS[J]. 2022, 第 1 作者32(46): http://dx.doi.org/10.1002/adfm.202207741.
[4] Li, Xing, Bian, Shaoquan, Zhao, Mingda, Han, Xiaowen, Liang, Jie, Wang, Kefeng, Jiang, Qing, Sun, Yong, Fan, Yujiang, Zhang, Xingdong. Stimuli-responsive biphenyl-tripeptide supramolecular hydrogels as biomimetic extracellular matrix scaffolds for cartilage tissue engineering. ACTA BIOMATERIALIA[J]. 2021, 第 2 作者131: 128-137, http://dx.doi.org/10.1016/j.actbio.2021.07.007.
[5] Zhiqiang Zheng, Shaoquan Bian, Zhiqiang Li, Zhiyang Zhang, Yuan Liu, Xinyun Zhai, Haobo Pan, Xiaoli Zhao. Catechol modified quaternized chitosan enhanced wet adhesive and antibacterial properties of injectable thermo-sensitive hydrogel for wound healing. CARBOHYDRATE POLYMERS[J]. 2020, 第 2 作者249:
[6] Bian, Shaoquan, Zheng, Zhiqiang, Liu, Yuan, Ruan, Changshun, Pan, Haobo, Zhao, Xiaoli. A shear-thinning adhesive hydrogel reinforced by photo-initiated crosslinking as a fit-to-shape tissue sealant. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2019, 第 1 作者7(42): 6488-6499, http://dx.doi.org/10.1039/c9tb01521c.
[7] Chen, Qingchang, Zheng, Chuping, Li, Yanqun, Bian, Shaoquan, Pan, Haobo, Zhao, Xiaoli, Lu, William W. Bone Targeted Delivery of SDF-1 via Alendronate Functionalized Nanoparticles in Guiding Stem Cell Migration. ACS APPLIED MATERIALS & INTERFACES[J]. 2018, 第 4 作者10(28): 23700-23710, http://ir.siat.ac.cn:8080/handle/172644/14727.
[8] He, Mengmeng, Sui, Junhui, Chen, Yafang, Bian, Shaoquan, Cui, Yani, Zhou, Changchun, Sun, Yong, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Localized multidrug co-delivery by injectable self-crosslinking hydrogel for synergistic combinational chemotherapy. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2017, 第 4 作者5(25): 4852-4862,
[9] Bian, Shaoquan, Cai, Hanxu, Cui, Yani, He, Mengmeng, Cao, Wanxu, Chen, Xuening, Sun, Yong, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Temperature and ion dual responsive biphenyl-dipeptide supramolecular hydrogels as extracellular matrix mimic-scaffolds for cell culture applications. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2017, 第 1 作者5(20): 3667-3674, https://www.webofscience.com/wos/woscc/full-record/WOS:000402112200007.
[10] Sui, Junhui, Cui, Yani, Cai, Hanxu, Bian, Shaoquan, Xu, Zhiyi, Zhou, Ling, Sun, Yong, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Synergistic chemotherapeutic effect of sorafenib-loaded pullulan-Dox conjugate nanoparticles against murine breast carcinoma. NANOSCALE[J]. 2017, 第 4 作者9(8): 2755-2767, https://www.webofscience.com/wos/woscc/full-record/WOS:000395876200012.
[11] Bian, Shaoquan, He, Mengmeng, Sui, Junhui, Cai, Hanxu, Sun, Yong, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. The self-crosslinking smart hyaluronic acid hydrogels as injectable three-dimensional scaffolds for cells culture. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2016, 第 1 作者140: 392-402, http://dx.doi.org/10.1016/j.colsurfb.2016.01.008.
[12] Li, Huanan, Cui, Yani, Sui, Junhui, Bian, Shaoquan, Sun, Yong, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Efficient Delivery of DOX to Nuclei of Hepatic Carcinoma Cells in the Subcutaneous Tumor Model Using pH-Sensitive Pullulan-DOX Conjugates. ACS APPLIED MATERIALS & INTERFACES[J]. 2015, 第 4 作者7(29): 15855-15865, https://www.webofscience.com/wos/woscc/full-record/WOS:000358897200020.
[13] Li, Huanan, Cui, Yani, Liu, Jun, Bian, Shaoquan, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Reduction breakable cholesteryl pullulan nanoparticles for targeted hepatocellular carcinoma chemotherapy. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2014, 第 4 作者2(22): 3500-3510, https://www.webofscience.com/wos/woscc/full-record/WOS:000336829400011.
[14] Li, Huanan, Bian, Shaoquan, Huang, Yihang, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. High drug loading pH-sensitive pullulan-DOX conjugate nanoparticles for hepatic targeting. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A[J]. 2014, 第 2 作者102(1): 150-159, http://www.corc.org.cn/handle/1471x/1936490.
[15] Sun, Yong, Zou, Wen, Bian, Shaoquan, Huang, Yihang, Tan, Yanfei, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Bioreducible PAA-g-PEG graft micelles with high doxorubicin loading for targeted antitumor effect against mouse breast carcinoma. BIOMATERIALS[J]. 2013, 第 3 作者34(28): 6818-6828, http://dx.doi.org/10.1016/j.biomaterials.2013.05.032.
[16] Sun, Yong, Huang, Yihang, Bian, Shaoquan, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Reduction-degradable PEG-b-PAA-b-PEG triblock copolymer micelles incorporated with MTX for cancer chemotherapy. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2013, 第 3 作者112: 197-203, http://dx.doi.org/10.1016/j.colsurfb.2013.07.056.
[2] Sun, Yong, Li, Xing, Zhao, Mingda, Chen, Yafang, Xu, Yang, Wang, Kefeng, Bian, Shaoquan, Jiang, Qing, Fan, Yujiang, Zhang, Xingdong. Bioinspired supramolecular nanofiber hydrogel through self-assembly of biphenyl-tripeptide for tissue engineering. BIOACTIVE MATERIALS[J]. 2022, 第 7 作者 通讯作者 8: 396-408, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7289678&detailType=1.
[3] Bian, Shaoquan, Hao, Liuzhi, Qiu, Xin, Wu, Jun, Chang, Hao, Kuang, GuanMing, Zhang, Sheng, Hu, Xiaohua, Dai, Yakang, Zhou, Zhiyong, Huang, Fangli, Liu, Chun, Zou, Xuenong, Liu, Wenguang, Lu, Willima W, Pan, Haobo, Zhao, Xiaoli. An Injectable Rapid-Adhesion and Anti-Swelling Adhesive Hydrogel for Hemostasis and Wound Sealing. ADVANCED FUNCTIONAL MATERIALS[J]. 2022, 第 1 作者32(46): http://dx.doi.org/10.1002/adfm.202207741.
[4] Li, Xing, Bian, Shaoquan, Zhao, Mingda, Han, Xiaowen, Liang, Jie, Wang, Kefeng, Jiang, Qing, Sun, Yong, Fan, Yujiang, Zhang, Xingdong. Stimuli-responsive biphenyl-tripeptide supramolecular hydrogels as biomimetic extracellular matrix scaffolds for cartilage tissue engineering. ACTA BIOMATERIALIA[J]. 2021, 第 2 作者131: 128-137, http://dx.doi.org/10.1016/j.actbio.2021.07.007.
[5] Zhiqiang Zheng, Shaoquan Bian, Zhiqiang Li, Zhiyang Zhang, Yuan Liu, Xinyun Zhai, Haobo Pan, Xiaoli Zhao. Catechol modified quaternized chitosan enhanced wet adhesive and antibacterial properties of injectable thermo-sensitive hydrogel for wound healing. CARBOHYDRATE POLYMERS[J]. 2020, 第 2 作者249:
[6] Bian, Shaoquan, Zheng, Zhiqiang, Liu, Yuan, Ruan, Changshun, Pan, Haobo, Zhao, Xiaoli. A shear-thinning adhesive hydrogel reinforced by photo-initiated crosslinking as a fit-to-shape tissue sealant. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2019, 第 1 作者7(42): 6488-6499, http://dx.doi.org/10.1039/c9tb01521c.
[7] Chen, Qingchang, Zheng, Chuping, Li, Yanqun, Bian, Shaoquan, Pan, Haobo, Zhao, Xiaoli, Lu, William W. Bone Targeted Delivery of SDF-1 via Alendronate Functionalized Nanoparticles in Guiding Stem Cell Migration. ACS APPLIED MATERIALS & INTERFACES[J]. 2018, 第 4 作者10(28): 23700-23710, http://ir.siat.ac.cn:8080/handle/172644/14727.
[8] He, Mengmeng, Sui, Junhui, Chen, Yafang, Bian, Shaoquan, Cui, Yani, Zhou, Changchun, Sun, Yong, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Localized multidrug co-delivery by injectable self-crosslinking hydrogel for synergistic combinational chemotherapy. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2017, 第 4 作者5(25): 4852-4862,
[9] Bian, Shaoquan, Cai, Hanxu, Cui, Yani, He, Mengmeng, Cao, Wanxu, Chen, Xuening, Sun, Yong, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Temperature and ion dual responsive biphenyl-dipeptide supramolecular hydrogels as extracellular matrix mimic-scaffolds for cell culture applications. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2017, 第 1 作者5(20): 3667-3674, https://www.webofscience.com/wos/woscc/full-record/WOS:000402112200007.
[10] Sui, Junhui, Cui, Yani, Cai, Hanxu, Bian, Shaoquan, Xu, Zhiyi, Zhou, Ling, Sun, Yong, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Synergistic chemotherapeutic effect of sorafenib-loaded pullulan-Dox conjugate nanoparticles against murine breast carcinoma. NANOSCALE[J]. 2017, 第 4 作者9(8): 2755-2767, https://www.webofscience.com/wos/woscc/full-record/WOS:000395876200012.
[11] Bian, Shaoquan, He, Mengmeng, Sui, Junhui, Cai, Hanxu, Sun, Yong, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. The self-crosslinking smart hyaluronic acid hydrogels as injectable three-dimensional scaffolds for cells culture. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2016, 第 1 作者140: 392-402, http://dx.doi.org/10.1016/j.colsurfb.2016.01.008.
[12] Li, Huanan, Cui, Yani, Sui, Junhui, Bian, Shaoquan, Sun, Yong, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Efficient Delivery of DOX to Nuclei of Hepatic Carcinoma Cells in the Subcutaneous Tumor Model Using pH-Sensitive Pullulan-DOX Conjugates. ACS APPLIED MATERIALS & INTERFACES[J]. 2015, 第 4 作者7(29): 15855-15865, https://www.webofscience.com/wos/woscc/full-record/WOS:000358897200020.
[13] Li, Huanan, Cui, Yani, Liu, Jun, Bian, Shaoquan, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Reduction breakable cholesteryl pullulan nanoparticles for targeted hepatocellular carcinoma chemotherapy. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2014, 第 4 作者2(22): 3500-3510, https://www.webofscience.com/wos/woscc/full-record/WOS:000336829400011.
[14] Li, Huanan, Bian, Shaoquan, Huang, Yihang, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. High drug loading pH-sensitive pullulan-DOX conjugate nanoparticles for hepatic targeting. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A[J]. 2014, 第 2 作者102(1): 150-159, http://www.corc.org.cn/handle/1471x/1936490.
[15] Sun, Yong, Zou, Wen, Bian, Shaoquan, Huang, Yihang, Tan, Yanfei, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Bioreducible PAA-g-PEG graft micelles with high doxorubicin loading for targeted antitumor effect against mouse breast carcinoma. BIOMATERIALS[J]. 2013, 第 3 作者34(28): 6818-6828, http://dx.doi.org/10.1016/j.biomaterials.2013.05.032.
[16] Sun, Yong, Huang, Yihang, Bian, Shaoquan, Liang, Jie, Fan, Yujiang, Zhang, Xingdong. Reduction-degradable PEG-b-PAA-b-PEG triblock copolymer micelles incorporated with MTX for cancer chemotherapy. COLLOIDS AND SURFACES B-BIOINTERFACES[J]. 2013, 第 3 作者112: 197-203, http://dx.doi.org/10.1016/j.colsurfb.2013.07.056.
科研活动
科研项目
（ 1 ） 基于适应性水凝胶的生物打印技术构建多级血管网络的研究, 负责人, 国家任务, 2023-01--2025-12
（ 2 ） 具有可调粘弹性的适应性水凝胶构建及其应用于生物打印的研究, 负责人, 地方任务, 2021-10--2024-09
（ 3 ） 蜘蛛黏胶仿生的潮湿表面粘附性材料研究及其作为创伤封闭剂的应用, 负责人, 地方任务, 2021-10--2024-10
（ 4 ） 快速粘附/抗溶胀可注射水凝胶实施神经外科手术伤口闭合, 负责人, 研究所自主部署, 2022-01--2025-01
（ 2 ） 具有可调粘弹性的适应性水凝胶构建及其应用于生物打印的研究, 负责人, 地方任务, 2021-10--2024-09
（ 3 ） 蜘蛛黏胶仿生的潮湿表面粘附性材料研究及其作为创伤封闭剂的应用, 负责人, 地方任务, 2021-10--2024-10
（ 4 ） 快速粘附/抗溶胀可注射水凝胶实施神经外科手术伤口闭合, 负责人, 研究所自主部署, 2022-01--2025-01