General

Ye Jian, Professor and Principal Investigator  

Dept：State Key Laboratory of Plant Genomics

Telephone：010-64807363；E-mail：jianye@im.ac.cnAdd：

NO.1 Beichen WestRoad,Chaoyang District,Beijing 100101,P.R.China​


Research Areas

Vector-borne diseases account for more than 17% of all infectious diseases in human, causing more than 1 million deaths annually. Due to its sessile host, about 80% of 1100 reported viruses in plants were found to be transmitted by insect vector and costs several billon US dollars annually. The main research interest for Prof. Ye’s lab is to underpin molecular mechanisms of multitrophic interactions which can be used to control virus infection by using invasive whitefly transmitted geminiviruses as model system. A real viral disease under field condition always involves in multitrophic interactions, mainly referring a tritrophic interactions to the living community of the virus, the host plants and the insect vector. They further form a network with the core--plant chemical and physic defense against herbivory. The plant defense system stimulates the ecological impacts of a few more trophic levels?on each other: the virus, the plant, the root microbiome, the herbivore, and its?natural enemies such as?hyperparasitoids?or higher-order predators, are also considered. The underpin of the molecular mechanisms in the multitrophic interactions will enhance our capacity to control insect-transmitted viral diseases by environmental-friend methodologies.


Education

Ph.D. (2000-2007),Institute of Microbiology, Chinese Academy of Sciences

B. S (1996-2000), Zhejiang University, China.


Experience

  • Principal Investigator, Professor,

Institute of Microbiology, Chinese Academy of Sciences (2014 to now)

  • Principal Investigator, Assistant Director (2013 to 2014)

Temasek Life Sciences Laboratory

  • Strategic Research Program (SRP) Manager, (2011—2012)

Temasek Life Sciences Laboratory

  • Research Fellow (2009- 2010) Temasek Life Sciences Laboratory, Singapore. 
  • Postdoctoral Fellow (2007- 2009)
    Temasek Life Sciences Laboratory, Singapore.  


Publications

   
Papers

    2017

1.      Sun YW, Wang CM, Wang N, Jiang XY, Mao HZ, Zhu CX, Wen FJ, Wang XH, Lu ZJ, Yue GH,Xu ZF, Ye J*. 2017. Manipulation of Auxin Response Factor 19 affects seed size in the woody perennial Jatropha curcas. Scientific reports. Srep40844

2016 

1. Jun Liu#, Shulin Deng#, HW Wu#, Ye J, Hui-Wen Wu, Hai-Xi Sun, and Nam-Hai Chua. 2016. CURLY LEAF Regulates Gene Sets Coordinating Seed Size and Lipid Biosynthesis in Arabidopsis. Plant physiology. 171 424-436 

2. Tang W#, Wu T#, Ye J, Sun J, Jiang Y, Yu J, Tang J, Chen G, Wang C, Wan J. 2016. SNP-based analysis of genetic diversity reveals important alleles associated with seed size in rice. BMC Plant Biology  16:93.

3.Wang N#, Yao YM#, Zhu CX, Wen FJ*, Ye J*. 2016 Towards sustainable protection against insect-borne plant viral diseases: phytohormones and beyond. Science Foundation in China. 24(2). 69-80. Review. Cover.

4.Pingzhi Zhao,Lubomir N. Sokolov, Jian Ye, Cheng-Yi Tang, Jisen Shi, Yan Zhen, Wenzhi Lan,Zhi Hong, Jinliang Qi, Gui-Hua Lu, Girdhar K. Pandey & Yong-Hua Yang. 2016 The LIKE SEX FOUR2 regulates root development by modulating reactive oxygen species homeostasis in Arabidopsis. Scientific reports. srep28683. 

5.Jin JJ#, Lee M#, Bai B#, Sun YW#, Qu J, Rahmadsyah, Yuzer A, Lim CH, Suwanto A, Sugiharti M, Wong LS, Ye J*, Chua NH* and Yue GH*.  Draft genome sequence of an elite Dura palm and whole-genome patterns of DNA variation in oil palm. 2. DNA Research. 2016. 23 (6): 527-533. 

 

   2015

1. Ye J*, Yang J, Sun Y, Zhao P, Gao S, Jung C, Qu J, Fang R, Chua NH*. 2015. Geminivirus Activates ASYMMETRIC LEAVES 2 to Accelerate Cytoplasmic DCP2-Mediated mRNA Turnover and Weakens RNA Silencing in Arabidopsis. PLoS Pathogens 11:e1005196. 4

2. Sun YW, Tee CS, Ma YH, Wang G, Yao XM, Ye J*. 2015. Attenuation of Histone Methyltransferase KRYPTONITE-mediated transcriptional gene silencing by Geminivirus. Scientific reports.5: 16476. 

3. Li R, Tee C, Jiang Y, Jiang X, Venkatesh P, Sarojam R, Ye J*. 2015. A terpenoid phytoalexin plays a role in basal defense of Nicotiana benthamiana against Potato virus X. Scientific Reports 5:9682.

4.Wang H, Niu Q, Wu HW, Liu J, Ye J, Yu N, Chua NH. 2015. Analysis of noncoding transcriptome in rice and maize uncovers roles of conserved lncRNAs associated with agriculture traits. The Plant Journal 84 2: 404-416. 

5. Lee M, Xia J, Zou Z, Ye J, Rahmadsyah, Alfiko Y, Jin J, Lieando J, Purnamasari M, Lim C, Suwanto A, Wong L, Chua N, Yue G. 2015. A consensus linkage map of oil palm and a major QTL for stem height. Scientific reports 5:8232. 

2014

6.Li R, Weldegergis BT, Li J, Jung C, Qu J, Sun Y, Qian H, Tee C, van Loon JJ, Dicke M, Chua NH, Liu SS, Ye J*. 2014. Virulence Factors of Geminivirus Interact with MYC2 to Subvert Plant Resistance and Promote Vector Performance. The Plant cell 26:4991-5008. 

7.Ye J, Qu J, Mao HZ, Ma ZG, Rahman NE, Bai C, Chen W, Jiang SY, Ramachandran S, Chua NH. 2014. Engineering geminivirus resistance in Jatropha curcus. Biotechnology for biofuels 7:149.

8.Ye J, Geng Y, Zhang B, Mao H, Qu J, Chua NH. 2014. The Jatropha FT ortholog is a systemic signal regulating growth and flowering time. Biotechnology for biofuels 7:19.

9.Ye J, Liu P, Zhu C, Qu J, Wang X, Sun Y, Sun F, Jiang Y, Yue G, Wang C. 2014. Identification of candidate genes JcARF19 and JcIAA9 associated with seed size traits in Jatropha. Functional & integrative genomics 14:757-766. 

10. Wang G, Sun Y, Xu R, Qu J, Tee C, Jiang X, Ye J. 2014. DNA-A of a highly pathogenic Indian cassava mosaic virus isolated from Jatropha curcas causes symptoms in Nicotiana benthamiana. Virus genes 48:402-405. 

2013 and before

11.Wang C, Ye J, Tang W, Liu Z, Zhu C, Wang M, Wan J. 2013. Loop nucleotide polymorphism in a putative miRNA precursor associated with seed length in rice (Oryza sativa L.). International journal of biological sciences 9:578-586. 

12.Wang CM, Liu P, Sun F, Li L, Liu P, Ye J, Yue GH. 2012. Isolation and identification of miRNAs in Jatropha curcas. International journal of biological sciences 8:418-429. 

13.Qu J#, Ye J#, Geng YF, Sun YW, Gao SQ, Zhang BP, Chen W, Chua NH. 2012. Dissecting functions of KATANIN and WRINKLED1 in cotton fiber development by virus-induced gene silencing. Plant physiology 160:738-748. 

14.Qu J, Mao HZ, Chen W, Gao SQ, Bai YN, Sun YW, Geng YF, Ye J*. 2012. Development of marker-free transgenic Jatropha plants with increased levels of seed oleic acid. Biotechnology for biofuels 5:10. 

15.Sun F, Liu P, Ye J, Lo LC, Cao S, Li L, Yue GH, Wang CM. 2012. An approach for jatropha improvement using pleiotropic QTLs regulating plant growth and seed yield. Biotechnology for biofuels 5:42. 

16.Gao S, Qu J, Chua NH, Ye J*. 2010. A new strain of Indian cassava mosaic virus causes a mosaic disease in the biodiesel crop Jatropha curcas. Archives of virology 155:607-612. 

17.Ye J, Qu J, Zhang JF, Geng YF, Fang RX. 2009. A critical domain of the Cucumber mosaic virus 2b protein for RNA silencing suppressor activity. FEBS letters 583:101-106. 

18.Ye J, Qu J, Bui HT, Chua NH. 2009. Rapid analysis of Jatropha curcas gene functions by virus-induced gene silencing. Plant biotechnology journal 7:964-976. 

19.Qu J#, Ye J#, Fang R. 2007. Artificial microRNA-mediated virus resistance in plants. Journal of virology 81:6690-6699. 

20.Xu Y#, Ye J#, Liu H, Cheng E, Yang Y, Wang W, Zhao M, Zhou D, Liu D, Fang R. 2008. DNA-templated CMV viral capsid proteins assemble into nanotubes. Chemical Communications 1:49-51. 



Patents

(1) Jian Ye,Jing Qu,Huizhu Mao,Microsomal ω6 Oleate Desaturases,2017.02.21,PCT9574205

(2) Jian Ye,Nam-Hai Chua,Jing Qu,Yunfeng Geng,Yunping Bu,Virus induced gene silencing (VIGS) for functional analysis of genes in cotton,2014.05.06,PCT8853493

(3) Jian Ye,Nam-Hai Chua,Jing Qu,Functional analysis of Jatropha curcas genes,2014.03.19,PCT8921655

       ​(4) Huizhu Mao,Jian Ye,Nam-Hai Chua,Genetic Transformation of Jatropha curcas,2013.01.22,PCT8609418


Students

现指导学生

马永焕  02  63228  

龚雨晴  02  63228  

徐爽   02  63228