1、鱼类病毒感染与免疫机制

2、鱼类病毒疫苗及诊断技术研发

有病毒学或免疫学背景，对解析鱼类抗病免疫分子机制及重要养殖鱼类病毒疫苗创制等研究工作感兴趣

2019-10--2020-10   美国宾夕法尼亚大学   联合培养博士
2014-09--2021-06   华中农业大学   博士
2010-09--2014-06   潍坊学院   学士

   

2026-01~现在, 中国科学院水生生物研究所, 副研究员
2024-01~2025-12,中国科学院水生生物研究所, 助理研究员
2021-07~2023-12,中国科学院水生生物研究所, 博士后

   

（1） Analysis of MHC class II-bound CyHV-2 peptides in Carassius gibelio using mass spectrometry, Journal of Virology, 2026, 
（2） Multi-omics analysis reveals that Bacillus spp. enhance mucosal antiviral immunity in teleost fish by mediating diglyceride production through lipid metabolism, Microbiome, 2025, 第 2 作者
（3） Design of antibody structure-guided epitope vaccines in silico to induce potent immune responses against emerging viruses, Journal of Virology, 2025, 
（4） Identification and characterization of a novel reovirus strain isolated fromgrass carp (Ctenopharyngodon idella), Virology Journal, 2025, 第 1 作者
（5） Segment-specific immune responses and microbial dynamics in the gut of largemouth bass (Micropterus salmoides) following viral infection, Fish & Shellfish Immunology, 2025, 
（6）  Single-cell atlas of the mandarin fish ovary reveals the trajectories of oogenesis and its immune microenvironment development, Aquaculture, 2025, 
（7） Newly discovered and conserved role of IgM against viral infection in an early vertebrate, eLife, 2025, 第 1 作者
（8） Ocular mucosal homeostasis of teleost fish provides insight into the coevolution between microbiome and mucosal immunity, Microbiome, 2024, 第 1 作者
（9） . Teleost swim bladder, an ancient air-filled organ that elicits mucosal immune responses, Cell Discovery, 2022, 第 3 作者
（10） Pharyngeal immunity in early vertebrates provides functional and evolutionary insight into mucosal homeostasis, Journal of Immunology, 2019, 第 1 作者

   

（ 1 ） 草鱼免疫球蛋白与 GCRV-II 互作机制及高效疫苗创制, 负责人, 地方任务, 2026-03--2029-03
（ 2 ） ITGαv和ITGβ2介导GCRV-Ⅱ入侵草鱼嗜性淋巴细胞的机制研究, 负责人, 国家任务, 2026-01--2029-12
（ 3 ） 鱼类抗病毒免疫, 负责人, 地方任务, 2025-09--2028-09
（ 4 ） mTOR/S6K1信号通路调控虹鳟肠黏膜B细胞抗病毒感染的机制研究, 负责人, 国家任务, 2024-01--2026-12
（ 5 ） 重要养殖鱼、虾高产和抗病性状形成的分子调控网络研究, 参与, 国家任务, 2022-08--2027-07

   

（1） Analysis of MHC class II-bound CyHV-2 peptides in Carassius gibelio using mass spectrometry, Journal of Virology, 2026, 
（2） Multi-omics analysis reveals that Bacillus spp. enhance mucosal antiviral immunity in teleost fish by mediating diglyceride production through lipid metabolism, Microbiome, 2025, 第 2 作者
（3） Design of antibody structure-guided epitope vaccines in silico to induce potent immune responses against emerging viruses, Journal of Virology, 2025, 
（4） Identification and characterization of a novel reovirus strain isolated fromgrass carp (Ctenopharyngodon idella), Virology Journal, 2025, 第 1 作者
（5） Segment-specific immune responses and microbial dynamics in the gut of largemouth bass (Micropterus salmoides) following viral infection, Fish & Shellfish Immunology, 2025, 
（6）  Single-cell atlas of the mandarin fish ovary reveals the trajectories of oogenesis and its immune microenvironment development, Aquaculture, 2025, 
（7） Newly discovered and conserved role of IgM against viral infection in an early vertebrate, eLife, 2025, 第 1 作者
（8） Ocular mucosal homeostasis of teleost fish provides insight into the coevolution between microbiome and mucosal immunity, Microbiome, 2024, 第 1 作者
（9） . Teleost swim bladder, an ancient air-filled organ that elicits mucosal immune responses, Cell Discovery, 2022, 第 3 作者
（10） Pharyngeal immunity in early vertebrates provides functional and evolutionary insight into mucosal homeostasis, Journal of Immunology, 2019, 第 1 作者

   

（ 1 ） 草鱼免疫球蛋白与 GCRV-II 互作机制及高效疫苗创制, 负责人, 地方任务, 2026-03--2029-03
（ 2 ） ITGαv和ITGβ2介导GCRV-Ⅱ入侵草鱼嗜性淋巴细胞的机制研究, 负责人, 国家任务, 2026-01--2029-12
（ 3 ） 鱼类抗病毒免疫, 负责人, 地方任务, 2025-09--2028-09
（ 4 ） mTOR/S6K1信号通路调控虹鳟肠黏膜B细胞抗病毒感染的机制研究, 负责人, 国家任务, 2024-01--2026-12
（ 5 ） 重要养殖鱼、虾高产和抗病性状形成的分子调控网络研究, 参与, 国家任务, 2022-08--2027-07