Research Areas
1. Stem cell therapy for brain and spinal cord disorders.
2. Electrical stimulation guided fate decision of neural stem cells.
3. Transcranial electrical stimulation regulated neurogenesis.
Education
2006-2011 PhD, China Pharmaceutical University, Nanjing, China
2002-2006 B.S., Hebei Medical University, Shijiazhuang, China
Experience
2021.01 - present, Associate Professor, SIAT, CAS
2018.06 - 2020.12, Visiting Associate Researcher, University of California at Davis
2012.11 - 2015.12, Research Associate, Cardiff University
Publications
Papers
（1） Transcriptomic analysis of rat brain response to alternating current electrical stimulation: unveiling insights via single-nucleus RNA sequencing, MedComm, 2024
（2） Ultra-Low-Dose UV-C Photo-stimulation Promotes Neural Stem Cells Differentiation via Presenilin 1 Mediated Notch and β-Catenin Activation, Mol Neurobiol ., 2024
（3） Intensity-dependent gamma electrical stimulation regulates microglial activation, reduces beta-amyloid load, and facilitates memory in a mouse model of Alzheimer’s disease, CELL & BIOSCIENCE, 2023
（4） Electric field stimulation boosts neuronal differentiation of neural stem cells for spinal cord injury treatment via PI3K/Akt/GSK-3β/β-catenin activation, CELL & BIOSCIENCE, 2023
（5） Intracranial alternating current stimulation facilitates neurogenesis in a mouse model of Alzheimer’s disease, ALZHEIMERS RESEARCH & THERAPY, 2020
（6）High-frequency repetitive transcranial magnetic stimulation improves functional recovery by inhibiting neurotoxic polarization of astrocytes in ischemic rats, JOURNAL OF NEUROINFLAMMATION, 2020
（7） Microglial TREM-1 receptor mediates neuroinflammatory injury via interaction with SYK in experimental ischemic stroke, CELLDEATHANDDISEASE, 2019