1、脑机接口检测调控芯片微系统

2、脑机接口智能算法

3、离体神经芯片与神经计算

   

0809Z1-生物电子学

脑机接口微电极阵列和芯片微系统

2005-09--2010-06   中国科学院电子学研究所   博士
2000-09--2004-06   北方工业大学   学士

研究生

博士

2023-07~现在, 中国科学院空天信息创新研究院, 创新特区首席科学家
2022-11~现在, 中国科学院空天信息创新研究院, 特聘研究骨干
2016-07~2022-11,中国科学院空天信息创新研究院, 副研究员
2010-07~2016-07,中国科学院电子学研究所, 助理研究员

2024-06-14-今,中国人工智能学会生物信息学与人工生命专委会,
2024-05-20-今,中国人工智能学会会员,
2023-02-15-今,中国神经科学学会脑机接口分会会员,
2018-03-31-今,中国电子学会生物医学电子学分会会员,
2016-11-30-今,中国研究型医院学会移动医疗专业委员会青年委员会委员,

1)       A dual-mode wireless microsystem for monitoring dopamine and spike changes with dexmedetomidine. Cyborg and Bionic Systems, 2026，通讯作者

2)       In Vitro Biological Neuronal Networks Achieve Low-Power Consumption and High-Speed Communication through Predictable Stimulation. ACS Sensors, 2026，通讯作者

3)       Dynamically monitor-regulating dopamine concentration and neural information transmission in targeted deep brain nuclei using integrated microelectrode array, Sensors and Actuators:B. Chemical, 2025, 通讯作者

4)       Targeted-modified multitransm microelectrode arrays enable simultaneous tracking of dopamine dynamics and cellular-level electrophysiological activity in the NAc during sleep-wake transitions. Research，2025，通讯作者

5)       NeuroDepth: An ultra long whole brain reachable multi-channel probe for real-1 time precise functional localization of deep human brain tumor margins. Microsystems &Nanoengineering, 2025，通讯作者

6)       Integrated dopamine sensing and 40 hz hippocampal stimulation improves cognitive performance in Alzheimer's mouse models. Nature Communications, 2025

7)       Chronic implantable flexible serpentine probe reveals impaired spatial coding of place cells in epilepsy, National Science Review, 2025 

8)       Long-term stability strategies of deep brain flexible neural interface, npj Flexible Electronics, 2025, 通讯作者

9)       Distinct neural activities in hippocampal subregions revealed using a high-performance wireless microsystem with PNPs/PEDOT:PSS-enhanced microelectrode arrays. Biosensors, 2025，通讯作者

10)    Deep brain implantable microelectrode arrays for functional localization and detection of the subthalamic nucleus in rats with Parkinson's Disease, Bio-design and manufacturing, 2024, 通讯作者

11)    Tentacle Microelectrode arrays uncover soft boundary neurons in hippocampal CA1, Advanced Science, 2024

12)    High-performance bidirectional microelectrode array for assessing sevoflurane anesthesia effects and in situ

electrical stimulation in deep brain regions, ACS Sensors, 2024, 通讯作者

13)    Real-time precise targeting of the subthalamic nucleus via transfer learning in a rat model of Parkinson's Disease based on microelectrode arrays, IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2024, 通讯作者

14)    High-throughput microelectrode arrays for precise functional localization of the globus pallidus internus, Cyborg and Bionic Systems, 2024, 通讯作者

15)    Neuronal activity in the ventral tegmental area during goal-directed navigation recorded by low-curvature microelectrode arrays, Microsystems &

Nanoengineering, 2024, 第 2 作者

16)    Wireless closed-loop deep brain stimulation using microelectrode array probes, Journal of Zhejiang University-SCIENCE B, 2024, 通讯作者

17)    Using human-induced pluripotent stem cell derived neurons on microelectrode arrays to model neurological disease: a review, Advanced Science, 2023, 

18)    Impaired spatial firing encoding of neurons in medial entorhinal cortex of the epileptic rat using microelectrode arrays, Research, 2023, 通讯作者

19)    Integrated three-electrode dual-mode detection chip for place cell analysis: dopamine facilitates the role of place cells in encoding spatial locations of novel environments and rewards, ACS Sensors, 2023, 通讯作者

20) Grid cell remapping under three-dimensional object and social landmarks detected by implantable microelectrode arrays for the medial entorhinal cortex, Microsystems &Nanoengineering, 2022, 通讯作者

（ 1 ） 高通道术中肿瘤边界精准识别的新模态脑机接口仪器, 负责人, 中国科学院计划, 2026-04--2029-03
（ 2 ） 神经芯片, 负责人, 国家任务, 2023-07--2025-10
（ 3 ） 睡眠-觉醒脑神经电活动高分辨感测与电刺激方法研究, 参与, 国家任务, 2023-01--2027-12
（ 4 ） 脑机接口新器件与系统前沿交叉研判项目, 参与, 国家任务, 2023-01--2023-12
（ 5 ） 微电极阵列及其记录系统研究, 负责人, 国家任务, 2022-11--2025-10
（ 6 ） 基于微纳电极与嵌入式系统的脑-机交互接口技术研究, 负责人, 国家任务, 2022-08--2025-12
（ 7 ） 微纳传感器智能精准功能定位帕金森靶点的关键技术与装置, 负责人, 国家任务, 2020-01--2023-12
（ 8 ） 神经再生功能信息原位探测纳米生物传感技术, 参与, 国家任务, 2020-01--2024-12

（1）植入式脑机接口调控技术现状与发展趋势   中国科学院雁栖青年论坛脑机接口与脑机融合前沿研究   2025-04-26
（2）神经微纳电极阵列单细胞检测与调控技术研究   《物理化学学报》创刊40周年学术研讨会暨能源催化科学与技术论坛   2024-11-03
（3）基于微电极阵列的脑重大疾病细胞水平神经信息检测与调控   第六届细胞生物信息学研讨会   2023-11-28
（4）细胞水平智能脑功能定位系统研究   第五届细胞生物信息学研讨会   2023-02-23
（5）Multi-level neural stimulation and dual-mode neural signal detection system based on implantable microelectrode array (MEA)    2020-07-20
（6）Abnormal Spontaneous Neuronal Discharge and Local Field Potential both in Cortex and Striatum of a Non-human Primate of Parkinson’s Disease using Implantable Microelectrode Arrays   2018-07-17
（7）Research on neural information detecting system measuring neuroelectricity in hippocampus in vivo and dopamine in vitro based on microelectrode array   2016-08-17

现指导学生

李书琦  硕士研究生  0809Z1-生物电子学  

王宣懿  硕士研究生  0809Z1-生物电子学  

王亮  硕士研究生  085403-集成电路工程