Plant genetics

Plant epigenetics

2005.9 ~ 2008.6, Ph. D., South China Botanical Garden, Chinese Academy of Sciences

2008.10 ~ 2012.7, Postdoctoral researcher, National Taiwan University

2012.9 ~ now, Researcher, South China Botanical Garden, Chinese Academy of Sciences

Selected Publication:

1.    Gu D., Chen C-Y., Zhao M., Zhao L., Duan X., Duan J.*, Wu K.*, Liu X.* (2017) Identification of HDA15-PIF1 as a Key Repression Module Directing the Transcriptional Network of Seed Germination in the Dark. Nucleic Acids Res. 12, 7137-7150.

2.    Zhao L., Peng T., Chen C., Ji R., Gu D., Li T., Zhang D., Tu, Y., Wu K, Liu X.* (2019) HY5 Interacts with the histone deacetylase HDA15 to repress hypocotyl cell elongation in photomorphogenesis. Plant Physiol. 180: 1450-1466

3.    Yang, J., Yuan, L., Yen, M.R., Zheng, F., Ji, R., Peng, T., Gu, D., Yang, S., Cui, Y., Chen, P.Y., Wu K.*, and Liu X.* (2020) SWI3B and HDA6 interact and are required for transposon silencing in Arabidopsis. Plant J., 102, 809-822.

4.    Zhao, M., Yang, S., Chen, C., Li, C., Shan, W., Lu, W., Cui, Y., Liu, X.* and Wu, K*. (2015).   Arabidopsis BREVIPEDICELLUS interacts with the SWI2/SNF2 chromatin remodeling ATPase BRAHMA to regulate KNAT2 and KNAT6 expression in control of inflorescence architecture. PLoS Genet. 11: e1005125.

5.    Tang Y^#, Liu X^#, Liu X, Li Y, Wu K,and Hou X. Arabidopsis NF-YCs mediate the light control of hypocotyl elongation via modulating histone acetylation, Mol. Plant, 2016 (Co-first author)

6.    Liu, X., Yang. S., Zhao M.L., Luo M., Yu C.W., Chen C.Y., Tai R., Wu K. (2014). Transcriptional repression by histone deacetylation in plants. Mol. Plant 7:764-772.

7.    Liu, X., Chen, C., Wang, K., Luo, M., Tai, R., Yuan. L., Zhao, M., Yang, S., Tian, G., Cui, Y., Hsieh, H. and Wu, K. (2013). PHYTOCHROME INTERACTING FACTOR3 Associates with the Histone Deacetylase HDA15 in Repression of Chlorophyll Biosynthesis and Photosynthesis in Etiolated Arabidopsis Seedlings. Plant Cell, 4, 1258-1273.

8.    Liu, X., Yu, C, Duan, J., Luo, M., Wang, K., Tian, G., Cui, Y., and Wu, K. (2012). HDA6 directly interacts with DNA methyltransferase MET1 and maintains transposable element silencing in Arabidopsis. Plant Physiol., 158, 119-129.

We are interested in understanding the molecular mechanism by which epigenetic factors regulate gene expression in plants. Our research program is focused on the histone acetylation, one of the most universal histone modifications in eukaryotes. Reversible histone acetylation and deacetylation play crucial roles in multiple development processes, as well in response to biotic and abiotic stresses. Beside histone proteins, acetylation also occurs in non-histone proteins. Non-histone acetylation plays an important roles in manipulating the turnover, subcellular localization and structure of proteins. Recently, we are also interested in the study the role of non-histone acetylation in plant development.

已指导学生

辜大川  博士研究生  071007-遗传学  

赵明磊  博士研究生  071010-生物化学与分子生物学  

赵林茂  博士研究生  071010-生物化学与分子生物学  

唐巧芳  硕士研究生  071007-遗传学  

李婷婷  硕士研究生  071010-生物化学与分子生物学  

彭滔  硕士研究生  085238-生物工程  

王晓婉  硕士研究生  071007-遗传学  

纪茹君  硕士研究生  085238-生物工程  

李志伟  博士研究生  071010-生物化学与分子生物学  

周宜洁  博士研究生  071010-生物化学与分子生物学  

现指导学生

韩露  硕士研究生  071010-生物化学与分子生物学  

邓玲  硕士研究生  071010-生物化学与分子生物学  

许婧妍  硕士研究生  071010-生物化学与分子生物学  

金霞  硕士研究生  071010-生物化学与分子生物学  

王雅寒  硕士研究生  086000-生物与医药  

纪茹君  博士研究生  071010-生物化学与分子生物学