主要从事生物医学检测方法研究及智能检测系统研制及应用。主持承担了国家级课题4项，省部级课题4项，总经费730.9万。作为核心骨干承担国家重大重点项目4项，中科院先导项目1项。2017年自然基金面上项目 “基于电化学免疫纸芯片的高灵敏度快速检测方法及其在绝经期女性雌激素检测中的应用”（2018-2021/80万）获得资助；此外还承担过自然基金青年项目“超痕量疾病标志物检测传感器研究”，国家重大科研仪器项目子课题“多层次调控与高通量神经信号同步检测仪器”；自然基金面上项目子课题“基于电化学免疫纸芯片的高灵敏度快速检测方法及其在绝经期女性雌激素检测中的应用”。

  近五年在Sensors and Actuators B, Biosensors & Bioelectronics 及 Analytica Chimica Acta等本领域顶级期刊及国际会议上发表SCI/EI论文60余篇，获授权专利20项。获得了2020年度北京自自然科学二等奖，2012年度北京科学技术二等奖，2014年度中科院电子所优秀青年，2015年北京"纳米之星"创业大赛优秀奖，2015年和2016年中科院电子所优秀职工。

   

0809Z1-生物电子学
080903-微电子学与固体电子学
080901-物理电子学

微纳生物传感器及其应用
脑认知机理及智能算法研究

2006-04--2009-06   中国科学院电子学研究所   博士
2003-07--2006-03   北京航空航天大学   硕士
1999-09--2003-06   北京航空航天大学   学士

研究生

博士

   

2020-01~现在, 中国科学院空天信息创新研究院, 副研究员
2018-07~2020-01,中国科学院电子学研究所, 副研究员
2009-07~2018-06,中国科学院电子学研究所, 助研

2018-11-01-今,中国研究型医院学会空间微生物与感染专业专业委员会, 委员
2018-10-26-今,中国研究型医院学会移动医疗专业委员会, 委员
2018-10-08-今,《中国临床医学》杂志, 编辑
2012-04-01-今,北京生理学会, 理事
2009-10-28-今,中国宇航学会航天医学工程与空间生物专业委员会, 委员

生物电子学

   

（1） 新型生物信息微纳传感器应用基础研究, 二等奖, 部委级, 2020
（2） 中国科学院电子学研究所优秀青年基金, 一等奖, 研究所（学校）, 2014
（3） 北京市科学技术二等奖, 二等奖, 省级, 2012

[1] 刘军涛, 蔡新霞, 徐声伟, 陆柏涛, 王怡丁, 范鹏辉, 邢宇, 王昊. 多参数生命体征的检测装置及检测方法. CN: [[[CN111685757A]]], [[["2020-09-22"]]].

[2] 刘军涛, 蔡新霞, 徐声伟, 邢宇, 陆柏涛. 一种脑电数据处理方法、装置以及计算机可读存储介质. CN: CN112515686B, 2022-12-30.

[3] 邢宇, 蔡新霞, 刘军涛, 张禹, 孙帅, 王杨, 明涛, 罗金平. 微型化智能便携式直接免疫的电化学检测装置及检测方法. CN: CN112098479B, 2022-09-02.

[4] 刘军涛, 蔡新霞, 徐声伟, 邢宇, 陆柏涛. 一种脑电数据处理方法、装置以及计算机可读存储介质. CN: CN112515686A, 2021-03-19.

[5] 邢宇, 蔡新霞, 刘军涛, 张禹, 孙帅, 王杨, 明涛, 罗金平. 微型化智能便携式直接免疫的电化学检测装置及检测方法. CN: CN112098479A, 2020-12-18.

[6] 刘军涛, 蔡新霞, 罗金平, 徐声伟. 临近空间自动采样检测装置及方法. CN2019103749486, 2019-05-07.

[7] 刘军涛, 蔡新霞, 刘欣阳, 徐声伟, 孔壮. 分离式脑电干电极. ZL2017109032016, 2017-09-08.

   

[1] 陆柏涛, 范鹏辉, 李明, 王怡丁, 杨固成, 莫凡, 徐兆杰, 单劲, 宋轶琳, 刘军涛, 吴一戎, 蔡新霞. Detection of Neuronal Defensive Discharges Information Transmission and Characteristics in the Periaqueductal Gray Double-Subregions Using PtNPs/PEDOT:PSS-modified Microelectrode Arrays. Microsystems & Nanoengineering[J]. 2023, 9(70): [2] 杨固成, 王怡丁, 徐兆杰, 张雪, 阮望, 莫凡, 陆柏涛, 范鹏辉, 戴玉川, 宋轶琳, 刘军涛, 蔡新霞. PtNPs/PEDOT:PSS-ModifiedMicroelectrode Arrays for Detection of the Discharge of Head Direction Cells in the Retrosplenial Cortex of Rats under Dissociation between Visual and Vestibular Inputs. Biosensors[J]. 2023, 13(496): /doi.org/10.3390/bios13050496-, [3] Botao Lu, Penghui Fan, Yiding Wang, Dai, Yuchuan, jingyu xie, Gucheng Yang, Fan Mo, Zhaojie Xu, Yilin Song, 刘军涛, Xinxia Cai. Neuronal Electrophysiological Activities Detection of Defense Behaviors Using an Implantable Microelectrode Array in the Dorsal Periaqueductal Gray. Biosensor[J]. 2022, 12(4): 193-205, [4] Tao Ming, Jinping Luo, Yu Xing, Yan Cheng, Juntao Liu, Shuai Sun, Fanli Kong, Shihong Xu, Yuchuan Dai, Jingyu Xie, Hongyan Jin, Xinxia Cai. Recent progress and perspectives of continuous in vivo testing device. MATERIALS TODAY BIO[J]. 2022, 16: 100341-, http://dx.doi.org/10.1016/j.mtbio.2022.100341.
[5] Xing, Yu, Liu, Juntao, Sun, Shuai, Ming, Tao, Wang, Yang, Luo, Jinping, Xiao, Guihua, Li, Xinrong, Xie, Jingyu, Cai, Xinxia. New electrochemical method for programmed death-ligand 1 detection based on a paper-based microfluidic aptasensor. BIOELECTROCHEMISTRY[J]. 2021, 140: http://dx.doi.org/10.1016/j.bioelechem.2021.107789.
[6] 蔡新霞. Ziyi Lin, Juntao Liu, Feng Duan, Rui Liu, Shengwei Xu, Xinxia Cai*,Electroencephalography symmetry in power, waveform and power spectrum in major depression. IEEE EMBC 2020. 2020, [7] Wang, Yang, Sun, Shuai, Luo, Jinping, Xiong, Ying, Ming, Tao, Liu, Juntao, Ma, Yuanyuan, Yan, Shi, Yang, Yue, Yang, Zhugen, Reboud, Julien, Yin, Huabing, Cooper, Jonathan M, Cai, Xinxia. Low sample volume origami-paper-based graphene-modified aptasensors for label-free electrochemical detection of cancer biomarker-EGFR. MICROSYSTEMS & NANOENGINEERING[J]. 2020, 6(1): https://doaj.org/article/c009a1c1051548759092e93dcba7731c.
[8] Wang, Hao, Liu, Juntao, Lu, Zeying, Dai, Yuchuan, Xie, Jingyu, Xu, Shengwei, Song, Yilin, Xiao, Guihua, Gao, Fei, Qu, Lina, Cai, Xinxia. Implanted multichannel microelectrode array for simultaneous electrophysiological signal detection of hippocampal CA1 and DG neurons of simulated microgravity rats. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2020, 531(3): 357-363, http://dx.doi.org/10.1016/j.bbrc.2020.07.079.
[9] Wang, Hao, Liu, Juntao, Lu, Zeying, Xu, Shengwei, Xie, Jingyu, Dai, Yuchuan, Xiao, Guihua, Song, Yilin, Zhang, Yu, Qu, Lina, Cai, Xinxia. Effects of Long-Term and Acute Hindlimb Unloading Model on Neuroelectrophysiological Signals of Hippocampal Interneurons and Pyramidal Cells Using Microelectrode Arrays. IEEE ACCESS[J]. 2020, 8: 198822-198831, https://doaj.org/article/81cdcd335f2641dc8ae714338cdc7c73.
[10] 蔡新霞. Yu Xing, Juntao Liu, Shuai Sun, Tao Ming, Guihua Xiao, Xinrong Li, Yu Zhang, Jinping Luo, Yue Yang, Shi Yan, Xinxia Cai*,Label-free microfluidic paper-based electrochemical aptasensor for the detection of programLabel-free microfluidic paper-based electrochemical aptasensor for the detection of programmed death ligand 1med death ligand 1. IEEE EMBC 2020. 2020, [11] Ming, Tao, Luo, Jinping, Liu, Juntao, Sun, Shuai, Xing, Yu, Wang, Hao, Xiao, Guihua, Deng, Yu, Cheng, Yan, Yang, Zhugen, Jin, Hongyan, Cai, Xinxia. Paper-based microfluidic aptasensors. BIOSENSORS & BIOELECTRONICS[J]. 2020, 170: http://dx.doi.org/10.1016/j.bios.2020.112649.
[12] 刘军涛. A folding paper-based aptasensor platform coated with novel nanoassembly for instant and highly sensitive detection of 17β-estradiol. ACS Sensors. 2019, [13] 刘军涛. Implanted Neural Microelectrode Array for In-situ Extracellular Action Potential and Local Field Potential Detection in Hippocampus of Simulated Microgravity Rats. IEEE Nano. 2019, [14] 蔡新霞. Zeying Lu、Shengwei Xu、Hao Wang、Juntao Liu、Fei Gao、Yilin Song、Jingyu Xie、Guihua Xiao、Yu Zhang、Yuchuan Dai、Yun Wang、Lina Qu、Xinxia Cai. Detection of Neuronal Activity in the Hippocampus of Sleep Deprived Rats Using Microelectrode Arrays. Acta Physico-Chimica Sinica, 2019, 36:1-7. Acta Physico-Chimica Sinica. 2019, [15] 刘军涛. Implantable Microelectrode Arrays for Electrophysiological Activity Detection in Cortex of Sleep Deprived Rats. IEEE Nano. 2019, [16] Wang, Yang, Luo, Jinping, Liu, Juntao, Sun, Shuai, Xiong, Ying, Ma, Yuanyuan, Yan, Shi, Yang, Yue, Yin, Huabing, Cai, Xinxia. Label-free microfluidic paper-based electrochemical aptasensor for ultrasensitive and simultaneous multiplexed detection of cancer biomarkers. BIOSENSORS & BIOELECTRONICS[J]. 2019, 136: 84-90, http://dx.doi.org/10.1016/j.bios.2019.04.032.
[17] Liu, Juntao, Liu, Xinyang, He, Enhui, Gao, Fei, Li, Ziyue, Xiao, Guihua, Xu, Shengwei, Cai, Xinxia. A novel dry-contact electrode for measuring electroencephalography signals. SENSORS AND ACTUATORS A-PHYSICAL[J]. 2019, 294: 73-80, http://dx.doi.org/10.1016/j.sna.2019.05.017.
[18] 刘军涛. Label-free paper-based immunosensor with graphemenanocomposites for electrochemical detection of follicle-stimulating hormone.. Engineering in Medicine & Biology Society IEEE,. 2018, [19] Liu, Juntao, Fan, Yan, Kong, Zhuang, Wang, Yang, Luo, Jinping, Xu, Shengwei, Jin, Hongyan, Cai, Xinxia. Smartphone-based rapid quantitative detection of luteinizing hormone using gold immunochromatographic strip. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 259: 1073-1081, http://dx.doi.org/10.1016/j.snb.2017.12.161.
[20] Yang Wang, Jinping Luo, Juntao Liu, Xinrong Li, Zhuang Kong, Hongyan Jin, Xinxia Cai. Electrochemical integrated paper-based immunosensor modified with multi-walled carbon nanotubes nanocomposites for point-of-care testing of 17β-estradiol. BIOSENSORS AND BIOELECTRONICS. 2018, 107: 47-53, http://dx.doi.org/10.1016/j.bios.2018.02.012.
[21] Liu, Juntao, Kong, Zhuang, Wang, Yang, Fan, Yan, Luo, Jinping, Xu, Shengwei, Jin, Hongyan, Cai, Xinxia, IEEE. A Rapid Quantitative Determination Method of Luteinizing Hormone with Gold Immunochromatographic Strip. 2017 39TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)null. 2017, 17-20, [22] Liu Juntao, Qu Shuxue, Luo Jinping, Wang Bin, Cai Xinxia. Portable System for Rapid Field Test of CEA in Human Serum Based on Chemiluminescence Enzyme Immunoassay. CHINESE JOURNAL OF ELECTRONICS[J]. 2017, 26(1): 152-155, [23] Liu, Xinyang, Liu, Juntao, Duan, Feng, Liu, Rui, Gai, Shuping, Xu, Shengwei, Sun, Jianhui, Cai, Xinxia. Inter-hemispheric frontal alpha synchronization of event-related potentials reflects memory-induced mental fatigue. NEUROSCIENCE LETTERS[J]. 2017, 653: 326-331, https://www.webofscience.com/wos/woscc/full-record/WOS:000405153900053.
[24] 蔡新霞. Yan Fan, Juntao Liu, Yang Wang, JinpingLuo, HuirenXu, ShengweiXu, XinxiaCai. A wireless point-of-care testing system for Neuron-specific enolase detection with paper-based microfluidic analytical devices. Biosensors and Bioelectronics. 2017, 95, 60-66.(SCI,IF=7.48). Biosensors and Bioelectronics. 2017, [25] 蔡新霞. Yang Wang, HuirenXu, JinpingLuo, Juntao Liu, Li Wang, Yan Fan, Shi Yan, Yue Yang, XinxiaCai. A novel label-free microfluidic paper-based immunosensor for highly sensitive electrochemical detection of carcinoembryonic antigen. Biosensors and Bioelectronics, 2016, 83:319-326. (SCI,IF=7.48). BIOSENSORSBIOELECTRONICS. 2016, [26] 刘军涛. 用于肿瘤标志物现场快速检测的便携式仪器的研制. 分析化学. 2016, [27] 刘军涛. Study of Clinical Sample Detection for LH with Lateral Flow Immuno- chromatographic Strip Using Support Vector Regression. Engineering in Medicine & Biology Society IEEE,. 2016, [28] Liu, Xinyang, Liu, Juntao, Gai, Shuping, Meyer, Kristina, Xu, Shengwei, Cai, Xinxia. Time-frequency distribution properties of event-related potentials in mental fatigue induced by visual memory tasks. NEUROREPORT[J]. 2016, 27(14): 1031-1036, http://www.corc.org.cn/handle/1471x/2375926.
[29] 刘军涛. Application of nanomaterials in electrochemical paper-based biomedical microfluidic devices.. European Journal of BioMedical Research. 2015, [30] []. Low sample volume origami-paper-based graphene-modified aptasensors for label-free electrochemical detection of cancer biomarker-EGFR | Microsystems & Nanoengineering. https://www.nature.com/articles/s41378-020-0146-2?error=cookies_not_supported&code=047acd04-004d-4eff-bf54-12109ae9ed74.

（1） A novel feature extractor based on wavelet and kernel PCA for spike sorting neural signals, Springer, 2014-10, 第 1 作者
（2） A novel and low-power wireless SOC design for pervasive bio-sensor applications, Taylor & Francis Group, 2015-05, 第 2 作者
（3） 脑电检测系统及其应用 & 细菌快速检测系统及其应用, 科学出版社, 2020-05, 第 1 作者

   

（ 1 ） 用于性激素即时检测的多参数直接免疫电化学质芯片及系统, 主持, 国家级, 2018-01--2021-12
（ 2 ） 基于电化学免疫纸芯片的高灵敏度快速检测方法及其在绝经期女性雌激素检测中的应用, 主持, 国家级, 2017-01--2020-12
（ 3 ） 多层次调控与高通量神经信号同步检测仪器, 参与, 国家级, 2016-01--2020-12
（ 4 ） 高时空分辨微纳电极阵列与神经信息光电调控检测系统, 参与, 国家级, 2017-07--2022-06
（ 5 ） 无标记电化学免疫检测芯片技术, 主持, 部委级, 2016-08--2022-12
（ 6 ） 肺癌标志物检测纸芯片及智能检测系统, 主持, 省级, 2020-01--2022-12

（1）Electroencephalography symmetry in power, waveform and power spectrum in major depression   2020-07-16
（2）高灵敏度无标记电化学微流控纸芯片   2019-04-13
（3）A Rapid Quantitative Determination Method of Luteinizing Hormone with Gold Immuno- chromatographic Strip   2018-07-23

合作单位包括：北京大学第一医院，北京肿瘤医院，国家纳米中心，中国航天员训练中心等