Prof. Lijuan Zhang, Shanghai Institute of Applied Physcis, Shanghai Advanced Research Institute


Adress: No. 239, Zhangheng RD, New Pudong District, Shanghai

Research Areas

  • Techniques of sychrotron radiation soft X-ray

  • Properties of nanobubbles/nanodroplets and their applications

  • Interfacial science


Sept. 2004-Jan. 2007     PhD, Shanghai Institute of Applied Physics, CAS, China

Sept., 2000 – Jun., 2003  Master studies in Physical Chemistry (Colloids and Interface Science), Shandong University, Jinan 250100,China

Professional Experience

Oct., 2018 – Present         Professor, Shanghai Advanced Research Institute, CAS, Shanghai 201204, China

Dec., 2016 – Sept., 2018   Professor, Shanghai Institute of Applied Physics, CAS, Shanghai 201204, China

Nov., 2009 – Nov., 2016   Associate professor, Shanghai Institute of Applied Physics, CAS, Shanghai 201204, China

Apr., 2007 – Oct., 2009      Postdoctor, Max Planck Institute for Polymer Research, Mainz, 55128, Germany


1.       Zhanli Geng, Limin Zhou, Lijuan Zhang,* Jun Hu*, Controllable Emulsification by Dissolved Gas in Water: Formation and Stability of Surfactant-free Oil Nanodroplets. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2022, accepted.

2.        Hengxin Fang, Juncheng Qi, Yao Wang, Kaiwei Yuan, Lijuan Zhang*, Jun Hu*, Interfacial Micropancakes: Gas or Contaminations? Langmuir 2022, 38, 26, 7914-7920.

3.        Kaiwei Yuan, Limin Zhou, Jing WangZhanli GengJuncheng QiXingya Wang, Lijuan Zhang*, Jun Hu*, Formation of Bulk Nanobubbles Induced by accelerated electrons Irradiation: Dependences on Dose Rates and Doses of Irradiation. Langmuir 2022, 38, 26, 7938-7944.

4.        Yuwen Ji, Jin Zheng, Zhanli Geng, Tingyuan Tan, Jun Hu, Lijuan Zhang*, Yi Zhang*, Controllable Formation of Bulk Perfluorohexane Nanodroplets by Solvent Exchange. Soft Matter 2022, 18, 425-433.

5.        Zhanli Geng, Limin Zhou, Zhou Fang, Jing Wang, Kaiwei Yuan, Lijuan Zhang,* Jun Hu*, Influence of the Dissolved Gas on the Interfacial Properties of Decane Surface Nanodroplets. Langmuir 2022, 38, 7, 2213-2219.

6.        Limin Zhou#, Shumin Yang#, Nannan Quan, Zhanli Geng, Shuo Wang, Binyu Zhao, Xingya Wang, Yaming Dong, Renzhong Tai, Jun Hu*, Lijuan Zhang*, Wetting Behavior of Surface Nanodroplets Regulated by Periodic Nanostructured Surfaces. ACS Appl. Mater. Interfaces 2021, 13, 55726−55734.

7.        Limin Zhou, Shuo Wang, Lijuan Zhang*, Jun Hu*, Generation and stability of bulk nanobubbles: A review and perspective. Current Opinion inColloid & Interface Science 2021, 53:101439.

8.        Shuo Wang, Limin Zhou, Xingya Wang, Jun Hu, Pan Li, Guanhua Lin, Yongxiang Gao,* Lijuan Zhang,* Chunlei Wang*. Collective Dynamics of Bulk Nanobubbles with Size-Dependent Surface Tension. Langmuir 2021, 37, 26, 7986-7994.

9.        Limin Zhou, Xingya Wang, Hyun-Joon Shin, Jian Wang, Renzhong Tai, Xuehua Zhang, Haiping Fang, Wei Xiao, Lei Wang, Chunlei Wang, Xingyu Gao*, Jun Hu*, Lijuan Zhang*, Ultrahigh Density of Gas Molecules Confined in Surface Nanobubbles in Ambient Water. J. Am. Chem. Soc. 2020, 142 (12), 5583-5593.

10.     Jing Wang, Kaiwei Yuan, Xingya Wang, Lijuan Zhang*, Jun Hu* Influence of Krypton Gas Nanobubbles on the Activity of Pepsin. Langmuir 2020, 36, 14070-14075.

11.     Zhou Fang, Xingya Wang, Limin Zhou, Lijuan Zhang*, Jun Hu*, Formation and Stability of Bulk Nanobubbles by Vibration. Langmuir 2020, 36, 2264−2270.

12.     Xinxing Chu, Jian Tang, Zhanli Geng, Xingya Wang, Gengyang Huo, Limin Zhou, Jing Wang, Kaiwei Yuan, Xiaodong Yang, Jun Hu*, Fang Yang*, Xingfei Zhou*, Lijuan Zhang*, Mechanical Properties of Sub-microbubbles with a Nanoparticle-decorated Polymer Shell. Langmuir 2019, 35(52), 17090-17095.

13.     Shuo Ke, Wei Xiao, Nannan Quan, Yaming Dong,* Lijuan Zhang,* Jun Hu*, Formation and Stability of Bulk Nanobubbles in Different Solutions. Langmuir 2019, 35, 5250−5256.

14.     Wei Xiao,* Yulong Zhao, Juan Yang, Yaxin Ren, Wei Yang, Xiaotao Huang,* Lijuan Zhang*, Effect of Sodium Oleate on the Adsorption Morphology and Mechanism of Nanobubbles on the Mica Surface. Langmuir 2019, 35, 9239−9245.

15.     Shuo Wang, Limin Zhou, Xingya Wang, Chunlei Wang, Yaming Dong, Yi Zhang, Yongxiang Gao, Lijuan Zhang*, Jun Hu*. Force spectroscopy revealed a high gas density state near the graphite substrate inside surface nanobubbles. Langmuir 2019, 35 (7), 2498–2505.

16.     Wei Xiao, Weiguang Zhou, Zhou Fang, Limin Zhou, Jun Wang*, Jun Hu*, Wenqing Qin, Guanzhou Qiu, Lijuan Zhang*, The Influence of Mixing on the Formation and Stability of Nanobubbles. J. Phys. Chem. B 2019, 123, 317-323.

17.     Zhou Fang, Lei Wang, Xingya Wang, Limin Zhou, Shuo Wang, Zhenglei Zou, Renzhong Tai, Lijuan Zhang*, Jun Hu*, Formation and Stability of Surface / Bulk Nanobubbles Produced by Decompression at Lower Gas Concentration. J. Phys. Chem. C 2018, 122, 22418−22423.

18.     Yong Guo†, Wei Xiao†, Wanfen Pu, Ju Hu, Jinzhou Zhao*, Lijuan Zhang*, CH4 Nanobubbles on the Hydrophobic Solid−Water Interface Serving as the Nucleation Sites of Methane Hydrate. Langmuir 2018, 34, 10181−10186.

19.     Wei Xiao, Shuo Ke, Nannan Quan, Limin Zhou, Jun Wang, * Lijuan Zhang,* Yaming Dong, Wenqing Qin, Guanzhou Qiu and Jun Hu.* The Role of Nanobubbles in the Precipitation and Recovery of Organic Phosphine-containing in Beneficiation Wastewater. Langmuir 2018, 34 (21), 6217–6224.

20.     Shengkun Yao, Jiadong Fan, Zhiyun Chen, Yunbing Zong, Jianhua Zhang, Zhibin Sun, Lijuan Zhang, Renzhong Tai,  Zhi Liu,  Chunying Chen and  Huaidong Jiang*. Three-dimensional ultrastructural imaging reveals nanoscale architecture of mammalian cells with potential nanomedicine. IUCrJ 2018, 5, 141-149.

21.     Liang Chen†, Guosheng Shi†, Jie Shen†, Bingquan Peng†, Bowu Zhang, Yuzhu Wang, Fenggang Bian, Jiajun Wang, Deyuan Li, Zhe Qian, Gang Xu, Gongping Liu, Jianrong Zeng, Lijuan Zhang, Yizhou Yang, Guoquan Zhou, Minghong Wu*, Wanqin Jin*, Jingye Li* and Haiping Fang*. Highly efficient ion rejection by graphene oxide membranes via ion-controlling interlayer spacing. Nature 2017, 550, 380-383.

22.     Lijuan Zhang, Yuebin Zhang, Jie Cheng, Lei Wang, Xingya Wang, Meng Zhang, Yi Gao, Jun Hu, Xuehua Zhang, Junhong Lü, Guohui Li, Renzhong Tai, Haiping Fang. Inert Gas Deactivates Protein Activity by Aggregation. Scientific Reports 2017, 7: 10176.

23.     Lei Wang, Xingya Wang, Lian sheng Wang, Jun Hu, Chunlei Wang, Binyu Zhao, Xuehua Zhang, Renzhong Tai, Mengdong He*, Liqun Chen, Lijuan Zhang*, Formation of Surface Nanobubbles on Nanostructured Substrates. Nanoscale 2017, 9, 1078–1086.

24.     Jie Qiu, Zhenglei Zou, Shuo Wang, Xingya Wang, Lei Wang, Yaming Dong, Hongwei Zhao*, Lijuan Zhang*, Jun Hu*, Formation and Stability of Bulk Nanobubbles Generated by Ethanol-water Exchange. ChemPhysChem 2017, 18, 1345 –1350.

25.     Xingya Wang, Binyu Zhao*, Jun Hu, Shuo Wang, Renzhong Tai, Xingyu Gao*, Lijuan Zhang*, Interfacial Gas Nanobubbles or Oil Nanodroplets? Physical Chemistry Chemical Physics 2017, 19, 1108--1114.

26.     Guosheng Shi, Yaru Dang, Tingting Pan, Xing Liu, Hui Liu, Shaoxian Li, Lijuan Zhang, Hongwei Zhao*, Shaoping Li, Jiaguang Han, Renzhong Tai, Yiming Zhu, Jichen Li, Qing Ji, R.A. Mole, Dehong Yu*, Haiping Fang*. Unexpectedly Enhanced Solubility of Aromatic Amino Acids and Peptides in an Aqueous Solution of Divalent Transition-Metal Cations. Phys. Rev. Lett. 2016, 117, 238102.

27.     Shuo Wang, Xingya Wang, Binyu Zhao, Lei Wang, Jie Qiu, Limin Zhou, Yaming Dong, Bin Li, Junhong Lv, Ying Wang, Yi Zhang, Lijuan Zhang*, Jun Hu*, Size-dependent Stiffness of Nanodroplets: a Quantitative Analysis of Interaction Between AFM Probe and Nanodroplets. Langmuir 2016, 32(43), 11230-11235.

28.     Binyu Zhao, Xingya Wang, Shuo Wang, Renzhong Tai, Lijuan Zhang*, Jun Hu*, In situ Measurement of Contact Angle and Surface Tension of Interfacial Nanobubbles in Ethanol Aqueous Solutions. Soft Matter 2016, 12(14): 3303-3309.

29.    Binyu Zhao, Xingya Wang, Yang Song, Jun Hu, Junhong Lv, Xingfei Zhou, Renzhong Tai, Xuehua Zhang*, Lijuan Zhang*, Stiffness and evolution of interfacial micropancakes revealed by AFM quantitative nanomechanical imaging. Phys. Chem. Chem. Phys. 2015, 17, 13598-13605.

30.    Xingya Wang, Binyu Zhao, Wangguo Ma, Ying Wang, Renzhong Tai, Xingfei Zhou* and Lijuan Zhang*, Interfacial Nanobubbles on Atomically Flat Substrates with Different Hydrophobicity. ChemPhysChem 2015, 16(5), 1003–1007.

31.    Yang Song, Binyu Zhao, Lijuan Zhang*, Junhong Lü, Shuo Wang, Yaming Dong, Jun Hu*, The origin of the “snap-in” in the force curve between AFM probe and the water/gas interface of nanobubbles. ChemPhysChem 2014, 15(3): 492-499.

32.    Binyu Zhao, Yang Song, Shuo Wang, Bin Dai, Lijuan Zhang,* Yaming Dong, Junhong Lv*, Jun Hu*, Mechanical mapping of nanobubbles by PeakForce atomic force microscopy. Soft Matter, 2013, 9, 8837-8843.

33.    Lijuan Zhang*, Binyu Zhao, Lian Xue, Zhi Guo, Yaming Dong, Haiping Fang, Renzhong Tai*, Jun Hu*, Imaging Interfacial Micro and Nano Bubbles by Scanning Transmission Soft X-ray Microscopy. Journal of Synchrotron Radiation, 2013, 20, 413-418.

34.    Lijuan Zhang, Chunlei Wang, Renzhong Tai, Jun Hu, Haiping Fang*. Morphology and Stability of Nanoscopic Gas States at Water/Solid Interface. ChemPhysChem 2012, 13, 2188-2195.

35.    Lijuan Zhang, Maria D’Acunzi, Michael Kappl, Arnout Imhof, Alfons van Blaaderen, Hans-Jürgen Butt, Robert Graf, Doris Vollmer. Tuning the mechanical properties of silica microcapsules. Physical Chemistry Chemical Physics 2010, 12, 15392-15398.

36.    Lijuan Zhang, Xuehua Zhang, Yi Zhang, Jun Hu, Haiping Fang*, The length scales for stable gas nanobubbles at liquid/solid surfaces. Soft Matter 2010, 6, 4515-4519.

37.    Lijuan Zhang, Xuehua Zhang, Chunhai Fan, Yi Zhang, Jun Hu*, Nanoscale Multiple Gaseous Layers on the Hydrophobic Surface. Langmuir 2009, 25, 8860-8864.

38.    Lijuan Zhang, Maria D’Acunzi, Michael Kappl, Günter K. Auernhammer, Doris Vollmer*, C. Van Kats, A. Van Blaaderen, Hollow Silica Spheres: Synthesis and Mechanical Properties. Langmuir 2009, 25, 2711-2717.

39.    Lijuan Zhang, Michael Kappl, Günter K. Auernhammer, Beate Ullrich, Hans-Jürgen Butt, Doris Vollmer*, Surface – induced Ordering of Liquid Crystal on Modified Surfaces. Progress in Colloid and Polymer Science 2008, 134, 39-47.

40.    Lijuan Zhang, Hao Chen, Zhaoxia Li, Haiping Fang, Jun Hu, Long Lifetime of Nanobubbles Due to High Inner Density. Science in China Series G: Physics, Mechanics & Astronomy 2008, 51, 219-224.

41.    Lijuan Zhang, Yi Zhang, Renjie Zhang, Xusheng Feng, In-situ AFM Investigations on Degradation of Self-assembled Monolayers on Mica: Effect of Humidity. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2007, 293, 195-200.

42.    Lijuan Zhang, Yi Zhang, Xuehua Zhang, Zhaoxia Li, Guangxia Shen, Ming Ye, Chun-hai Fan, Haiping Fang*, Jun Hu*, Electrochemically Controlled Formation and Growth of Hydrogen Nanobubbles. Langmuir 2006, 22, 8109-8113.

43.    Lijuan Zhang, Huabin Wang, Investigation of Elasticity of Polymer Nanoparticle by Vibrating Scanning Polarization Force Microscopy. Chinese Physics Letters 2006, 23, 2315-2318.

44.    Lijuan Zhang, Hongguo Liu, Renjie Zhang, Li Zhang, Dongjin Qian, Yingdi Mu, Xiling Yu, Xusheng Feng, The Mineralization Process of Calcium Phosphate Induced by the LB Films of Porphyrin. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2005, 257-58, 307-312.

45.    Lijuan Zhang, Hongguo Liu, Xusheng Feng, Renjie Zhang, Li Zhang, Yingdi Mu, Jincheng Hao, Dongjin Qian, Yufeng Lou, Mineralization Mechanism of Calcium Phosphates Under Three Kinds of Langmuir Monolayers. Langmuir 2004, 20, 2243-2249.

46.    Lijuan Zhang, Hongguo Liu, Xusheng Feng*, Dongjin Qian, Li  Zhang, Xiling Yu, Qingling Feng, Study on Growth of Hydroxyapatite Induced by Dipalmitoylphosphatidylcholine Langmuir Monolayer. Thin solid Films 2004, 458, 287-291.

47.    Lijuan Zhang, Xusheng Feng, Hongguo Liu, Dongjin Qian, Li Zhang, Xiling Yu, Fuzhai Cui, Hydroxyapatite/collagen Composite Materials Formation in Simulated Body Fluid Environment. Materials Letters 2004, 58, 719-722. 


1.      Spectro Nanoscopy 2019 Workshop, November 13-15, 2019, SSRF, Shanghai, Conference Secretary.

2.      Conference on Nanobubbles, Nanodroplets and Their Applications, NANOBUBBLE2018, October 16-19, 2018, Suzhou, Conference Secretary.

3.      Lijuan Zhang, Inert Gas Deactivates Protein Activity by Aggregation, The 8th Biennial Australian Colloid & Interface Symposium, 29th of Jan.-2nd of Feb., Coffs Harbour, NSW (talk

4.      Conference on Nanobubbles, Gas-filled Micropancakes and Their Applications, NANOBUBBLE2014, October 21-24, 2014, Shanghai, Conference Secretary.

5.      Li-Juan Zhang(张立娟), Binyu Zhao, Xingya Wang, Jun Hu, Haiping Fang, Interfacial Nanobubbles investigated by Synchrotron Radiation Techniques, Conference on Nanobubbles, Gas-filled Micropancakes and Their Applications, NANOBUBBLE2014)” October 21-24, 2014, Shanghai (talk).

6.      Guohui Li, Lijuan Zhang, Junhong Lv, Haiping Fang, Jun Hu, Wangguo Ma, Xia Du, Jie Cheng, Lei Wang, Xingya Wang, Exploration on Mechanism of Anesthesia of Gas, Conference on Nanobubbles, Gas-filled Micropancakes and Their Applications, NANOBUBBLE2014)” Octomber 21-24, 2014, Shanghai (talk).