基本信息
臧坤 中国科学院水生生物研究所
电子邮件: zangkun@ihb.ac.cn
通信地址: 湖北省武汉市武昌区东湖南路7号
邮政编码: 430000
电子邮件: zangkun@ihb.ac.cn
通信地址: 湖北省武汉市武昌区东湖南路7号
邮政编码: 430000
研究领域
藻类固碳机制与应用研究;合成生物学;蛋白质结构与功能
招生信息
招生专业
071007-遗传学
招生方向
藻类固碳机制与应用
招生专业
071007-遗传学
招生方向
藻类固碳机制与应用
研究领域
藻类固碳机制与应用研究;合成生物学;蛋白质结构与功能
招生信息
招生专业
071007-遗传学
招生方向
藻类固碳机制与应用
招生专业
071007-遗传学
招生方向
藻类固碳机制与应用
教育背景
2026-03--中国科学院水生生物研究所 研究员2019-02--2026-01 德国马克斯普朗克生物化学研究所 博士后2014-09--2018-06 中国科学院海洋研究所 博士研究生2011-08--2014-06 上海海洋大学 硕士研究生2007-09--2011-07 中国农业大学 学士
教育背景
2026-03--中国科学院水生生物研究所 研究员2019-02--2026-01 德国马克斯普朗克生物化学研究所 博士后2014-09--2018-06 中国科学院海洋研究所 博士研究生2011-08--2014-06 上海海洋大学 硕士研究生2007-09--2011-07 中国农业大学 学士
工作经历
工作简历
2026-03~现在, 中国科学院水生生物研究所, 研究员2019-02~2026-01,德国马克斯普朗克生物化学研究所, 博士后
工作简历
2026-03~现在, 中国科学院水生生物研究所, 研究员2019-02~2026-01,德国马克斯普朗克生物化学研究所, 博士后
工作经历
工作简历
2026-03~现在, 中国科学院水生生物研究所, 研究员2019-02~2026-01,德国马克斯普朗克生物化学研究所, 博士后
工作简历
2026-03~现在, 中国科学院水生生物研究所, 研究员2019-02~2026-01,德国马克斯普朗克生物化学研究所, 博士后
出版信息
发表论文
(1) Stages of biomolecular condensate formation in pro-β-carboxysome assembly, NATURE PLANTS, 2026, 第 1 作者(2) Structural insight into ligand interactions of thymidylate synthase from white spot syndrome virus, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2025, 第 2 作者(3) The challenge of engineering Rubisco for improving photosynthesis, FEBS LETTERS, 2023, 第 2 作者(4) Scaffolding protein CcmM directs multiprotein phase separation in β-carboxysome biogenesis, NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2021, 第 1 作者(5) Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 第 5 作者(6) Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed, JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 第 2 作者(7) 白斑综合征病毒与凡纳滨对虾dUTP焦磷酸酶的结构与功能研究, 2018, 第 1 作者(8) Structural basis for specific calcium binding by the polycystic-kidney-disease domain of Vibrio anguillarum protease Epp, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 第 2 作者(9) The putative siderophore-interacting protein from Vibrio anguillarum : protein production, analysis, crystallization and X-ray crystallographic studies, ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2018, 第 2 作者(10) The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner, JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 第 1 作者(11) Evidences for involvement of growth hormone and insulin-like growth factor in ovarian development of starry flounder (Platichthys stellatus), FISHPHYSIOLOGYANDBIOCHEMISTRY, 2017, 第 5 作者(12) Molecular and transcriptional characterization of GTHs and mPR during ovarian maturation in rock bream Oplegnathus fasciatus, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL GENETICS AND PHYSIOLOGY, 2015, 第 6 作者(13) 星突江鲽胰岛素样生长因子I的体外重组表达及生物活性分析, Prokaryotic expression and bioactivity analysis of growth hormone and insulin-like growth factor-I from Platichthys stellatus, 中国工程科学, 2015, 第 2 作者(14) Insulin-like growth factors I and II in starry flounder (Platichthys stellatus): molecular cloning and differential expression during embryonic development, FISH PHYSIOLOGY AND BIOCHEMISTRY, 2015, 第 2 作者(15) 星突江鲽胰岛素样生长因子II的原核表达与生物活性分析, Prokaryotic expression and bioactivity analysis of insulin-like growth factor–II from Platichthys stellatus, 中国水产科学, 2015, 第 1 作者(16) Molecular and transcriptional characterization of GTHs and mPR during ovarian maturation in rock bream Oplegnathus fasciatus, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY, 2015, 第 6 作者(17) 漠斑牙鲆(Paralichthys lethostigma)LHβ基因克隆及其在卵巢不同发育期的表达特征, Molecular Cloning and Differential Expression of LH β Subunit During the Ovarian Maturation Cycle of Paralichthys lethostigma, 渔业科学进展, 2014, 第 2 作者(18) 星突江鲽生长激素基因的克隆及体外重组表达分析, Molecular cloning and in vitro expression of growth hormone gene from Platichthys stellatus, 水产学报, 2014, 第 1 作者(19) 两种养殖条件下牙鲆的血液生理生化指标比较分析, Comparative analysis of blood physiological and biochemical characteristics between pond and indoor tank-culture of Japanese flounder Paralichthys olivaceus, 渔业科学进展, 2013, 第 1 作者
发表论文
(1) Stages of biomolecular condensate formation in pro-β-carboxysome assembly, NATURE PLANTS, 2026, 第 1 作者(2) Structural insight into ligand interactions of thymidylate synthase from white spot syndrome virus, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2025, 第 2 作者(3) The challenge of engineering Rubisco for improving photosynthesis, FEBS LETTERS, 2023, 第 2 作者(4) Scaffolding protein CcmM directs multiprotein phase separation in β-carboxysome biogenesis, NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2021, 第 1 作者(5) Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 第 5 作者(6) Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed, JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 第 2 作者(7) 白斑综合征病毒与凡纳滨对虾dUTP焦磷酸酶的结构与功能研究, 2018, 第 1 作者(8) Structural basis for specific calcium binding by the polycystic-kidney-disease domain of Vibrio anguillarum protease Epp, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 第 2 作者(9) The putative siderophore-interacting protein from Vibrio anguillarum : protein production, analysis, crystallization and X-ray crystallographic studies, ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2018, 第 2 作者(10) The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner, JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 第 1 作者(11) Evidences for involvement of growth hormone and insulin-like growth factor in ovarian development of starry flounder (Platichthys stellatus), FISHPHYSIOLOGYANDBIOCHEMISTRY, 2017, 第 5 作者(12) Molecular and transcriptional characterization of GTHs and mPR during ovarian maturation in rock bream Oplegnathus fasciatus, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL GENETICS AND PHYSIOLOGY, 2015, 第 6 作者(13) 星突江鲽胰岛素样生长因子I的体外重组表达及生物活性分析, Prokaryotic expression and bioactivity analysis of growth hormone and insulin-like growth factor-I from Platichthys stellatus, 中国工程科学, 2015, 第 2 作者(14) Insulin-like growth factors I and II in starry flounder (Platichthys stellatus): molecular cloning and differential expression during embryonic development, FISH PHYSIOLOGY AND BIOCHEMISTRY, 2015, 第 2 作者(15) 星突江鲽胰岛素样生长因子II的原核表达与生物活性分析, Prokaryotic expression and bioactivity analysis of insulin-like growth factor–II from Platichthys stellatus, 中国水产科学, 2015, 第 1 作者(16) Molecular and transcriptional characterization of GTHs and mPR during ovarian maturation in rock bream Oplegnathus fasciatus, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY, 2015, 第 6 作者(17) 漠斑牙鲆(Paralichthys lethostigma)LHβ基因克隆及其在卵巢不同发育期的表达特征, Molecular Cloning and Differential Expression of LH β Subunit During the Ovarian Maturation Cycle of Paralichthys lethostigma, 渔业科学进展, 2014, 第 2 作者(18) 星突江鲽生长激素基因的克隆及体外重组表达分析, Molecular cloning and in vitro expression of growth hormone gene from Platichthys stellatus, 水产学报, 2014, 第 1 作者(19) 两种养殖条件下牙鲆的血液生理生化指标比较分析, Comparative analysis of blood physiological and biochemical characteristics between pond and indoor tank-culture of Japanese flounder Paralichthys olivaceus, 渔业科学进展, 2013, 第 1 作者
出版信息
发表论文
(1) Stages of biomolecular condensate formation in pro-β-carboxysome assembly, NATURE PLANTS, 2026, 第 1 作者(2) Structural insight into ligand interactions of thymidylate synthase from white spot syndrome virus, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2025, 第 2 作者(3) The challenge of engineering Rubisco for improving photosynthesis, FEBS LETTERS, 2023, 第 2 作者(4) Scaffolding protein CcmM directs multiprotein phase separation in β-carboxysome biogenesis, NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2021, 第 1 作者(5) Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 第 5 作者(6) Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed, JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 第 2 作者(7) 白斑综合征病毒与凡纳滨对虾dUTP焦磷酸酶的结构与功能研究, 2018, 第 1 作者(8) Structural basis for specific calcium binding by the polycystic-kidney-disease domain of Vibrio anguillarum protease Epp, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 第 2 作者(9) The putative siderophore-interacting protein from Vibrio anguillarum : protein production, analysis, crystallization and X-ray crystallographic studies, ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2018, 第 2 作者(10) The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner, JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 第 1 作者(11) Evidences for involvement of growth hormone and insulin-like growth factor in ovarian development of starry flounder (Platichthys stellatus), FISHPHYSIOLOGYANDBIOCHEMISTRY, 2017, 第 5 作者(12) Molecular and transcriptional characterization of GTHs and mPR during ovarian maturation in rock bream Oplegnathus fasciatus, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL GENETICS AND PHYSIOLOGY, 2015, 第 6 作者(13) 星突江鲽胰岛素样生长因子I的体外重组表达及生物活性分析, Prokaryotic expression and bioactivity analysis of growth hormone and insulin-like growth factor-I from Platichthys stellatus, 中国工程科学, 2015, 第 2 作者(14) Insulin-like growth factors I and II in starry flounder (Platichthys stellatus): molecular cloning and differential expression during embryonic development, FISH PHYSIOLOGY AND BIOCHEMISTRY, 2015, 第 2 作者(15) 星突江鲽胰岛素样生长因子II的原核表达与生物活性分析, Prokaryotic expression and bioactivity analysis of insulin-like growth factor–II from Platichthys stellatus, 中国水产科学, 2015, 第 1 作者(16) Molecular and transcriptional characterization of GTHs and mPR during ovarian maturation in rock bream Oplegnathus fasciatus, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY, 2015, 第 6 作者(17) 漠斑牙鲆(Paralichthys lethostigma)LHβ基因克隆及其在卵巢不同发育期的表达特征, Molecular Cloning and Differential Expression of LH β Subunit During the Ovarian Maturation Cycle of Paralichthys lethostigma, 渔业科学进展, 2014, 第 2 作者(18) 星突江鲽生长激素基因的克隆及体外重组表达分析, Molecular cloning and in vitro expression of growth hormone gene from Platichthys stellatus, 水产学报, 2014, 第 1 作者(19) 两种养殖条件下牙鲆的血液生理生化指标比较分析, Comparative analysis of blood physiological and biochemical characteristics between pond and indoor tank-culture of Japanese flounder Paralichthys olivaceus, 渔业科学进展, 2013, 第 1 作者
发表论文
(1) Stages of biomolecular condensate formation in pro-β-carboxysome assembly, NATURE PLANTS, 2026, 第 1 作者(2) Structural insight into ligand interactions of thymidylate synthase from white spot syndrome virus, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2025, 第 2 作者(3) The challenge of engineering Rubisco for improving photosynthesis, FEBS LETTERS, 2023, 第 2 作者(4) Scaffolding protein CcmM directs multiprotein phase separation in β-carboxysome biogenesis, NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2021, 第 1 作者(5) Structural basis of staphylococcal Stl inhibition on a eukaryotic dUTPase, INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2021, 第 5 作者(6) Structural analysis of a shrimp thymidylate synthase reveals species-specific interactions with dUMP and raltitrexed, JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2020, 第 2 作者(7) 白斑综合征病毒与凡纳滨对虾dUTP焦磷酸酶的结构与功能研究, 2018, 第 1 作者(8) Structural basis for specific calcium binding by the polycystic-kidney-disease domain of Vibrio anguillarum protease Epp, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 第 2 作者(9) The putative siderophore-interacting protein from Vibrio anguillarum : protein production, analysis, crystallization and X-ray crystallographic studies, ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2018, 第 2 作者(10) The dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner, JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 第 1 作者(11) Evidences for involvement of growth hormone and insulin-like growth factor in ovarian development of starry flounder (Platichthys stellatus), FISHPHYSIOLOGYANDBIOCHEMISTRY, 2017, 第 5 作者(12) Molecular and transcriptional characterization of GTHs and mPR during ovarian maturation in rock bream Oplegnathus fasciatus, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL GENETICS AND PHYSIOLOGY, 2015, 第 6 作者(13) 星突江鲽胰岛素样生长因子I的体外重组表达及生物活性分析, Prokaryotic expression and bioactivity analysis of growth hormone and insulin-like growth factor-I from Platichthys stellatus, 中国工程科学, 2015, 第 2 作者(14) Insulin-like growth factors I and II in starry flounder (Platichthys stellatus): molecular cloning and differential expression during embryonic development, FISH PHYSIOLOGY AND BIOCHEMISTRY, 2015, 第 2 作者(15) 星突江鲽胰岛素样生长因子II的原核表达与生物活性分析, Prokaryotic expression and bioactivity analysis of insulin-like growth factor–II from Platichthys stellatus, 中国水产科学, 2015, 第 1 作者(16) Molecular and transcriptional characterization of GTHs and mPR during ovarian maturation in rock bream Oplegnathus fasciatus, JOURNAL OF EXPERIMENTAL ZOOLOGY PART A-ECOLOGICAL AND INTEGRATIVE PHYSIOLOGY, 2015, 第 6 作者(17) 漠斑牙鲆(Paralichthys lethostigma)LHβ基因克隆及其在卵巢不同发育期的表达特征, Molecular Cloning and Differential Expression of LH β Subunit During the Ovarian Maturation Cycle of Paralichthys lethostigma, 渔业科学进展, 2014, 第 2 作者(18) 星突江鲽生长激素基因的克隆及体外重组表达分析, Molecular cloning and in vitro expression of growth hormone gene from Platichthys stellatus, 水产学报, 2014, 第 1 作者(19) 两种养殖条件下牙鲆的血液生理生化指标比较分析, Comparative analysis of blood physiological and biochemical characteristics between pond and indoor tank-culture of Japanese flounder Paralichthys olivaceus, 渔业科学进展, 2013, 第 1 作者
科研活动
科研项目
( 1 ) 中国科学院水生生物研究所引才计划青年项目, 负责人, 研究所自主部署, 2026-04--2029-12
科研项目
( 1 ) 中国科学院水生生物研究所引才计划青年项目, 负责人, 研究所自主部署, 2026-04--2029-12
科研活动
科研项目
( 1 ) 中国科学院水生生物研究所引才计划青年项目, 负责人, 研究所自主部署, 2026-04--2029-12
科研项目
( 1 ) 中国科学院水生生物研究所引才计划青年项目, 负责人, 研究所自主部署, 2026-04--2029-12