1) Modulation of synaptic transmission and plasticity;

2) Network dynamics underlying emotion.

1997-2002  Undergraduate study on BioMedical Engineering, Zhejiang University, Hangzhou, China

2002-2005  Graduate study on Physics, Tsinghua University, Beijing, China

2005-2010  PhD student of Max-Planck Institute for Biophysical Chemistry (Supervisor: Dr. Takeshi Sakaba, in the Laboratory of Prof. Erwin Neher, Nobel prize laureate in medicine 1991) Goettingen, Germany

2010 PhD Thesis: “The role of short-term synaptic plasticity in neuronal microcircuit” (summa cum laude)

   

2011-2014, PostDoc researcher in Laboratory of Brain Physiology (Director: Drs. Alain Marty and Isabel Llano), CNRS and University Paris Descartes, Paris, France

2014-2018, Associated Professor, School of Life Science, University of Science and Technology of China, Hefei, China

2019-2020, Professor, School of Life Science, University of Science and Technology of China, Hefei, China

2020-now, Professor, Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Shenzhen, China 

   

1.       Chen YF^#, Hong ZX^#, Wang JY, Liu KL, Liu J, Lin JB, Feng SJ, Zhang TH, Shan L, Guo PY, Lin YP, Li T, Chen Q, Jiang XD, Li AN, Li X, Li YT, Wilde JJ, Bao J*, Dai J*, and Lu ZH* Circuit-specific gene therapy reverses core symptoms in a primate Parkinson’s disease model. Cell. 2023 Nov 22;186(24):5394-5410.e18.

2.      Hu JX, Shi YM, Zhang JM, Huang XF, Wang Q, Zhao H, Shen JW, Chen ZP, Song W, Zheng P, Zhan SL, Sun YP, Cai PF, An K, Ouyang CJ, Zhao BZ, Zhou QX, Xu L, Xiong W, Zhang Z, Meng JJ, Chen JT, Ma YQ, Zhao H, Zhang M, Qu K, Hu J, Luo MH, Xu FQ, Chen XW, Xiong Y, Bao J*, Xue T* Melanopsin retinal ganglion cells mediate light-promoted brain development. Cell. 2022 Aug 18;185(17):3124-3137.

3.  Bao J, Graupner M, Astorga G, Collin T, Jalil A, Indriati DW, Bradley J, Shigemoto R and Llano I (2020). Synergism of type 1 metabotropic and ionotropic glutamate receptors in cerebellar molecular layer interneurons in vivo. eLife, 9, e56839

4.  An K#, Zhao H#*, Miao Y, Xu Q, Li YF, Ma YQ, Shi YM, Shen JW. Meng JJ, Chen JT, Bao J, and Xue T*† (2020). A Circadian Rhythm-gated Subcortical Visual Circuit for Nighttime Light Induced Depressive-like Behaviors, Nat. Neurosci. Accepted.

5.  Ma Y#, Bao J#*, Zhang Y#, Li Z, Zhou Z, Zhou X, Wan C, Huang L, Zhao Y, Han G*, Xue  T*. Mammalian Near-Infrared Image Vision through Injectable and Self-Powered Retinal Nanoantennae. Cell, 2019, 177(2): 243-255

6.  Cheng J, Huang X, Liang Y, Xue T, Wang L*, Bao J*. Plasticity of Light-induced Concurrent Glutamatergic and GABAergic Quantal Events in the Suprachiasmatic Nucleus, Journal of Biological Rhythms, 2018, 33(1):65-75

7.  Astorga G, Bao J, Franconville R, Jalil A, Bradley J, Llano I. An excitatory GABA loop operating in vivo. Frontiers in Cellular Neuroscience, 2015, 9, 275.

8.  Huang CH, Bao J, and Sakaba T. Multivesicular Release Differentiates the Reliability of Synaptic Transmission between the Visual Cortex and the Somatosensory Cortex. Journal of Neuroscience, 2010, 30:11994 – 12004.

9.  Bao J* , Reim K, Sakaba T*. Target-dependent feed-forward inhibition mediated by short-term synaptic plasticity in the cerebellum. Journal of Neuroscience, 2010, 30:8171-8179.

10.  Bibitchkov D, Bao J, and Neher E. Information transmission by synapses with short-term synaptic plasticity. BMC Neuroscience, 2007, 8(Suppl 2), P90. 

     (# equal contributions, *co-corresponding authors)