Research interests:

Biological effects and safety evaluation of various nanomaterials; 

Application of nuclear analytical techniques in environmental and biological study; 

Single cell analysis by mass spectrometry

Graduated from Fudan University of Applied Chemistry in 1989. 

Got Ph.D degree from Institute of High Energy Physics, Chinese Academy of Sciences in 1998. The doctoral dissertation obtained “National Outstanding Doctoral Dissertations” award in 2001.

1. 1. Hanqing Chen^#, Ruifang Zhao^#, Bing Wang, Lingna Zheng, Hong Ouyang, Hailong Wang, Xiaoyan Zhou, Dan Zhang, Zhifang Chai, Yuliang Zhao, Weiyue Feng*, Acute Oral Administration of Single-Walled Carbon Nanotubes Increases Intestinal Permeability and Inflammatory Responses: Association with the Changes in Gut Microbiota in Mice. Adv. Healthcare Mater. 2018, 7(13):1701313. 

2. Hanqing Chen, Ruifang Zhaob, Bing Wang, Chengxu Cai, Lingna Zheng, Hailong Wang, Meng Wang, Hong Ouyang, Xiaoyan Zhou, Zhifang Chai, Yuliang Zhao, Weiyue Feng, The effects of orally administered Ag, TiO₂ and SiO₂ nanoparticles on gut microbiota composition and colitis induction in mice, NanoImpact, 2017, 8, 80-88.

3. Li, J.^§, Chen, H.^§, Wang, B., Cai, C., Yang, X.*, Chai, Z., Feng, W.* ZnO nanoparticles act as supportive therapy in DSS-induced ulcerative colitis in mice by maintaining gut homeostasis and activating Nrf2 signaling. Sci. Rep. 2017, 7:43126.

4.  Hailong Wang, Meng Wang, Bing Wang, Lingna Zheng, Hanqing Chen, Zhifang Chai, Weiyue Feng^*, Interrogating the variation of element masses and distribution patterns in single cells using ICP-MS with a high efficiency cell introduction system. Anal. Bioanal. Chem. 2017, 409: 1415-1423.

5. Xiaoyan Zhou^†, Bing Wang^†, Tu Lan, Hanqing Chen, Hailong Wang, Ye Tao, Zhihong Li, Kurash Ibrahim, Dongqi Wang*, Weiyue Feng*, Chirality of Graphene Oxide Humic Acid Sandwich Complex Induced by a Twisted, Long-Range-Ordered Nanostructure. J. Phys. Chem. C, 2016, 120: 25789-25795.

6. Hanqing Chen, Bing Wang, Ruifang Zhao, Di Gao, Ming Guan, Lingna Zheng, Xiaoyan Zhou, Zhifang Chai, Yuliang Zhao, Weiyue Feng*, Co-culture with low-dose SWCNT attenuates bacterial invasion and inflammation in human enterocyte-like Caco-2 cells. Small, 2015, 11: 4366-4378.

7. Bing Wang, Xiaoyan Zhou, Dongqi Wang,* Jun-Jie Yin, Hanqing Chen, Xingfa Gao, Jing Zhang, Kurash Ibrahim, Zhifang Chai, Weiyue Feng* and Yuliang Zhao, Structure and Catalytic Activities of Ferrous Center Confined on the Interface between Carbon Nanotube and Humic Acid. Nanoscale, 2015, 7: 2651-2658.

8. Hailong Wang^#, Bing Wang^#, Meng Wang, Lingna Zheng, Hanqing Chen, Zhifang Chai, Yuliang Zhao, Weiyue Feng*, Time-resolved ICP-MS Analysis of Mineral Element Contents and Distribution Patterns in Single Cells. Analyst, 2014, 140: 523-531.

9. Wang, Meng; Zheng, Ling-Na; Wang, Bing; Chen, Hanqing; Zhao, Yuliang; Chai, Zhifang; Reid, Helen; Sharp, Barry; Feng, Weiyue*, Quantitative analysis of gold nanoparticles in single cells by laser ablation inductively coupled plasma-mass spectrometry, Anal. Chem. 2014, 86: 10252-10256.

10. Bing Wang, Xiao He, Zhiyong Zhang,* Yuliang Zhao, Weiyue Feng*, Nanomaterials in vivo: Blood Circulation and Organ Clearance. Acc. Chem. Res. 2013, 46(3): 761-769.

11. Hanqing Chen, Bing Wang, Di Gao, Ming Guan, Lingna Zheng, Hong Ouyang, Zhifang Chai, Yuliang Zhao, Weiyue Feng* Broad-Spectrum Antibacterial Activity of Carbon Nanotubes to Human Gut Bacteria. Small 2013, 9(16): 2735-2746.

12. Bing Wang, Jun-Jie Yin, Xiaoyan Zhou, Ibrahim Kurash, Zhifang Chai, Yuliang Zhao,* Weiyue Feng*, Physicochemical Origin for Free Radical Generation of Iron Oxide Nanoparticles in Biomicroenvironment: Catalytic Activities Mediated by Surface Chemical States, J. Phys. Chem. C 2013, 117: 383-392.

13. Huajian Wang, Meng Wang, Bing Wang, Ming Li, Hanqing Chen, Xiaohan Yu, Ke Wang, Zhifang Chai, Yuliang Zhao, Weiyue Feng*, Immunogold labeling technique with X-ray fluorescence microscopy reveals the enrichment ratios of Cu and Zn with the metabolism of APP and the formation of Amyloid-b plaque in a mouse model of Alzheimer’s disease, Metallomics, 2012, 4: 1113–1118.

14. Motao Zhu, Yiye Li, Jian Shi, Weiyue Feng, Guangjun Nie,* and Yuliang Zhao*, Exosomes as Extrapulmonary Signaling Conveyors for Nanoparticle-Induced Systemic Immune Activation. Small 2012, 8(3): 404–412.

15. Huajian Wang, Meng Wang, Bing Wang, Ming Li, Hanqing Chen, Xiaohan Yu, Yuliang Zhao, Weiyue Feng* and Zhifang Chai, The distribution profile and oxidation states of biometals in APP transgenic mouse brain: dyshomeostasis with age and as a function of the development of Alzheimer's disease. Metallomics, 2012, 4: 289-296.

已指导学生

王华建  博士研究生  070322-生物无机化学  

李明  硕士研究生  070301-无机化学  

朱墨桃  博士研究生  070322-生物无机化学  

陈汉清  博士研究生  070322-生物无机化学  

周晓艳  博士研究生  070301-无机化学  

郑令娜  博士研究生  070301-无机化学  

王海龙  博士研究生  070301-无机化学  

张丹  硕士研究生  070301-无机化学  

现指导学生

李雪  博士研究生  070301-无机化学  

周爽  博士研究生  0703Z2-生物无机化学  

陈伟  硕士研究生  0703Z2-生物无机化学