电子邮件： gliu@sioc.ac.cn
通信地址： 上海市零陵路345号
邮政编码： 200032
研究领域
Organic Chemistry, Organometallic Chemistry
• Transition metal-catalyzed fluorination of alkenes, alkynes, and arenes.
• Mechanistic study to address C-F bond formation in organometallic chemistry.
• Transition metal-catalyzed oxidative functionalization of alkenes and arenes by using O2 and H2O2 as oxidant.
• Synthesis of novel fluorinated heterocycle and .Arenes.
招生信息
招生专业: 化学
招生方向: 有机化学
教育背景
1996-09--1999-08 中科院大连化学物理研究所 理学硕士学位
1991-09--1995-07 南京理工大学 工学学士学位
学历
学位
工作经历
• 1996,9-1999,8 中科院大连化学物理研究所，获理学硕士；
• 1999,9-2002,8 中科院上海有机化学研究所，获理学博士；
• 2003,3-2005,7 美国Lehigh大学，博士后；
• 2005,8-2007,7 美国威斯康辛大学麦迪逊分校化学系,研究助理；
• 2007,7- 中科院上海有机所，“****”入选者,研究员。
出版信息
1. Claudio, Martinez; Yichen, Wu; Adam, B. Weinstein; Shannon, S Stahl;* Guosheng, Liu;* Kilian, Muniz,* “Palladium-Catalyzed Intermolecular Aminoacetoxylation of Alkenes and the Influence of PhI(OAc)2 on Aminopalladation Stereoselectivity.” J. Org. Chem. 2013, online.
2. Zhang, Zuxiao; Wang, Fei; Mu, Xin; Chen, Pinhong; Liu, Guosheng,* “Copper-Catlalyzed Regioselective Fluorination of Allylic Halides” Angew. Chem. Int. Ed. 2013, in press.
3. Peng, Haihui; Wang, Hao-Yang; Guo, Yin-Long; Liu, Guosheng,* “Palladium-Catalyzed Intermolecular Fluoroesterification of Styrenes: Exploration and Mechanistic Insight” Chem. Sci. 2013, in press.
4. Liu, Qilun; Chen, Pinhong; Liu, Guosheng,* “Palladium-Catalyzed C-C Triple Bond Cleavage: Efficient synthesis of 4H-benzo[d][1,3]oxazin-4-ones” ACS Catalysis, 2013, 3, 178-181 (Invited Paper).
5. Zhu, Haitao; Liu, Guosheng.* “Pd-Catalyzed Intermolecular Aminofluorination of Styrenes” Acta. Chim. Sinica. 2012, 70, 2404-2407.
6. Zhang, Hao; Chen, Pinhong; Liu, Guosheng.* “Palladium-catalyzed Arylakylation of Unactivated Alkenes: Pyridine Promote C-H Acitivation” Synlett, 2012, 23, 2749-2752 (Invited paper for C-H bond activation Cluster).
7. Liu, Guosheng* “Transition Metal-Catalyzed Fluorination of Unsaturated Carbon-Carbon Multibonds: A New Strategy for Fluorinated Heterocycles Synthesis.” Org. Biomol. Chem. 2012, 6243-6248 (Invited Review).
8. Xu, Tao; Liu, Guosheng* “A Concise and Selective Synthesis of 4-Fluoroisoquinolines and 4-Fluoropyrrolo[a]isoquinolines: Silver-Catalyzed Fluroination of Alkynes” Org. Lett, 2012, 14, 5416-5419.
9. Wu, Tao; Zhang, Hao; Liu, Guosheng* “Organocatalyzed Arylalkylation of Alkenes” Tetrahedron 2012, 52, 6450-6452. (Invited paper to the celebration of Prof. Zhangjie Shi for his Tetrahedron Award)
10. Xu, Tao; Liu, Guosheng* “Silver-Catalyzed Fluorination” SynLett, 2012, 23, 955-958. (Synpacts).
11. Mu, Xin; Wu, Tao; Wang Hao-yang; Guo, Yin-long; Liu, Guosheng* “Palladium-catalyzed Oxidative Aryltrifluoromethylation of Activated Alkenes at Room Temperature” J. Am. Chem. Soc. 2012, 134, 878-881.
12. Yin, Guoyin; Wu, Tao; Liu, Guosheng* “Highly Selective Palladium-Catalyzed Chloroamination of Unactivated Alkenes by using Hydrogen Peroxide as Oxidant” Chem. Eur. J. 2012, 18, 451-455.
13. Wu, Tao; Mu, Xin; Liu, Guosheng* “Palladium-Catalyzed Oxidative Arylalkylation of Activated Alkenes via Dual C-H Bonds Cleavage of Arenes and Acetonitriles” Angew. Chem. Int. Ed. 2011, 50, 12578-12581.
14. Xu, Tao; Qiu, Shuifa; Liu, Guosheng* “Palladium-Catalyzed Intramolecular Aminofluorination of Styrene” Chin. J. Chem. 2011, 29, 2785-2790. (Invited Paper on the occasion of Prof . Weiyuan Huang’s 90th birthday).
15. Wu, Yichen; Liu, Guosheng* “Organocatalyzed Cycloaddition of CO2 and Aziridines” Tetrahedron Lett. 2011, 52, 6540-6542.
16. Xu, Tao; Mu, Xin; Peng, Haihui; Liu, Guosheng* “Silver-Catalyzed Intramolecular Aminofluorination of Activated Allenes” Angew. Chem. Int. Ed. 2011, 50, 8176-8179.
17. Mu, Xin; Chen, Shujun; Zheng, Xinliang; Liu, Guosheng* “Palladium-Catalyzed Trifluoromethylation of Indoles at Room Temperature” Chem. Eur. J. 2011, 17, 6039-6042.
18. Peng, Haihui; Liu, Guosheng* “Palladium-Catalyzed Tandem Fluorination and Cyclization of Enynes” Org. Lett. 2011, 13, 772-775. (Featured in Synfact, 2011, 12, 518)
19. Chen, Shujun; Wu, Tao; Zhen, Xinliang; Liu, Guosheng* “Highly selective Palladium-Catalyzed Oxidative Intramolecular Aminonitroxylation of Alkenes” Synlett, 2011, 891-894. (Invited Paper for the contribution of Prof. Xiyan Lu and Prof. Lixin Dai in Organic Chemistry).
20. Xu, Tao; Qiu, Shuifa; Liu, Guosheng* “Palladium-catalyzed intra- and intermolecular hydroamination of Styrenes”, J. Organometallic. Chem. 2011, 696, 46-49. (Invited Paper for the special issue on the H-B addition to C-C double bond).
21. Yin， Guoyin；Wu， Yichen；Liu，Guosheng* “Scope and Mechanism of Allylic C-H Amination of Terminal Alkenes by the Palladium/PhI(OPiv)2 Catalyst System: Insights into the Effect of Naphthoquinone”, J. Am. Chem. Soc. 2010, 132, 11978-11987. (This paper was listed as one of the journal’s Top 20 most downloaded papers in August of 2010)
22. Qiu, Shuifa; Xu, Tao; Zhou, Juan; Guo, Yanlong; Liu, Guosheng* “Palladium-Catalyzed Intermolecular Aminofluorination of Styrenes”, J. Am. Chem. Soc. 2010, 132, 2856-2857.
23. Wu, Yicheng; Liu, Guosheng* “Palladium-Catalyzed Allylic C-H Bond Functionalization of Olefins”, Top. Cur. Chem. 2010, 292, 195-209.
24. Wu, Tao; Yin, Guoyin; Liu, Guosheng* “Palladium-Catalyzed Intramolecular Aminofluorination of Unactivated Alkenes”, J. Am. Chem. Soc. 2009, 131, 16354-16355. (Featured in Synfact, 2010, 3, 276)
25. Wu, Liang; Qiu, Shuifa; Liu, Guosheng* “Brønsted Base-Modulated Regioselective Pd-Catalyzed Intramolecular Aerobic Oxidative Amination of Alkenes:Formation of Seven-Membered Amides and Evidence for Allylic C-H Activation.” Org. Lett. 2009, 11, 2707-2710.
26. Qiu, Shuifa; Wei, Yunyang; Liu, Guosheng* “Palladium-Catalyzed Intramolecular Hydro- amination of Allenes Coupled to Aerobic Alcohol Oxidation.” Chem. Eur. J. 2009, 15, 2751-2755.
27. Liu, Guosheng;* Yin, Guoyin; Wu, Liang; “Palladium-catalyzed intermolecular aerobic oxidative amination of terminal alkenes: efficient synthesis of linear allylamine derivatives.” Angew. Chem. Int. Ed. 2008, 47, 4733-4736.
28. Yin, Guoyin; Liu, Guosheng* “Palladium-catalyzed oxidative cyclization of enyne with hydrogen peroxide as the oxidant.” Angew. Chem. Int. Ed. 2008, 47, 5442-5445. (Hot paper, and Featured in Synfact, 2008, 10, 1066)
1. Liu, Guosheng;* Wu, Yichen, “Bathocupronie”, in e-EROS Encyclopedia of Reagents for Organic Synthesis (D. Crich, P. L. Fuchs, A. B. Charette, T Rovis, Ed.), Wiley-Interscience, 2011.
2. Mu, Xin; Liu, Guosheng,* “Chapter 11, Dioxygen-Coupled Palladium and Copper-Catalyzed Csp2-H Functionalization: Reactions and Mechanisms” in C-H and C-X Bond Functionalization: Transition Metal Mediation (X. Ribas, Ed.) RSC Publishing, 2013.
3. Chen, Pinhong; Liu, Guosheng;* Engle Keary M; Yu Jin-Quan,* “High-Valent Palladium in Catalysis”, in Houben-Weyl: Science of Synthesis knowledge Updates, volume 1: Compounds with Transition-Metal-Carbon p-Bond and Compounds of Group 10-8 (Ni, Pt, Co, Rh, Ir, Fe, Os), (B. M. Trost, P. J. Plietker, Ed.), Thieme: New York, 2013.
4. 刘国生 (Liu Guosheng)，“绿色氧化”，10000 个科学难题-化学卷，267-269页，“10000 个科学难题”化学编委会主编，科学出版社，2009 年。
5. 刘国生 (Liu Guosheng)，“金属催化的合成反应”，高速发展的中国化学1982-2012，科学出版社，2012年。
发表论文
[2] 刘国生. Asymmetric Palladium-Catalyzed Oxycarbonylation of Terminal Alkenes: Efficient Access to β-Hydroxy Alkylcarboxylic Acids.. Angew. Chem. Int. Ed.. 2021,
[3] Tian, Bing, Chen, Pinhong, Leng, Xuebing, Liu, Guosheng. Palladium-catalysed enantioselective diacetoxylation of terminal alkenes. NATURE CATALYSIS[J]. 2021, 4(2): 172-179, https://www.webofscience.com/wos/woscc/full-record/WOS:000619599800009.
[4] Hu, Zhoumi, Fu, Liang, Chen, Pinhong, Cao, Weiguo, Liu, Guosheng. Enantioselective Intermolecular Aminoalkynylation of Styrenes via Copper-Catalyzed Radical Relay. ORGANIC LETTERS[J]. 2021, 23(1): 129-134, http://dx.doi.org/10.1021/acs.orglett.0c03826.
[5] Wu, Lianqian, Zhang, Zhihan, Wu, Dunqi, Wang, Fei, Chen, Pinhong, Lin, Zhenyang, Liu, Guosheng. Anionic Bisoxazoline Ligands Enable Copper-Catalyzed Asymmetric Radical Azidation of Acrylamides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2021, 60(13): 6997-7001, https://www.webofscience.com/wos/woscc/full-record/WOS:000618750900001.
[6] Chen, Chaohuang, Hou, Chuanqi, Chen, Pinhong, Liu, Guosheng. Palladium(II)-Catalyzed Aminotrifluoromethoxylation of Alkenes: Mechanistic Insight into the Effect of N-Protecting Groups. CHINESE JOURNAL OF CHEMISTRY[J]. 2020, 38(4): 346-350, https://www.webofscience.com/wos/woscc/full-record/WOS:000513913500001.
[7] 刘国生. Copper-Catalyzed Benzylic C–H Bond Thiocyanation: Enabling Late-Stage Diversifications.. CCS Chemistry. 2020,
[8] Zhou, Song, Zhang, Guoyu, Fu, Liang, Chen, Pinhong, Li, Yibiao, Liu, Guosheng. Copper-Catalyzed Asymmetric Cyanation of Alkenes via Carbonyl-Assisted Coupling of Alkyl-Substituted Carbon-Centered Radicals. ORGANIC LETTERS[J]. 2020, 22(16): 6299-6303, http://dx.doi.org/10.1021/acs.orglett.0c02085.
[9] Fu, Liang, Gressies, Steffen, Chen, Pinhong, Liu, Guosheng. Recent Advances and Perspectives in Transition Metal-Catalyzed 1,4-Functionalizations of Unactivated 1,3-Enynes for the Synthesis of Allenes. CHINESE JOURNAL OF CHEMISTRY[J]. 2020, 38(1): 91-100, http://lib.cqvip.com/Qikan/Article/Detail?id=7101214828.
[10] Wu, Lianqian, Wang, Lei, Chen, Pinghong, Guo, YinLong, Liu, Guosheng. Enantioselective Copper-Catalyzed Radical Ring-Opening Cyanation of Cyclopropanols and Cyclopropanone Acetals. ADVANCED SYNTHESIS & CATALYSIS[J]. 2020, 362(11): 2189-2194, https://www.webofscience.com/wos/woscc/full-record/WOS:000522520700001.
[11] Li, Xiaonan, Qi, Xiaoxu, Hou, Chuanqi, Chen, Pinhong, Liu, Guosheng. Palladium(II)-Catalyzed Enantioselective Azidation of Unactivated Alkenes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2020, 59(39): 17239-17244, http://dx.doi.org/10.1002/anie.202006757.
[12] 刘国生. Asymmetric Coupling of Carbon-Centered Radical Adjacent to Nitrogen: Copper-Catalyzed Cyanation and Etherification of Enamides.. Angew. Chem. Int. Ed.. 2020,
[13] Jiang, Chao, Wang, Lei, Zhang, Honggang, Chen, Pinhong, Guo, YinLong, Liu, Guosheng. Enantioselective Copper-Catalyzed Trifluoromethylation of Benzylic Radicals via Ring Opening of Cyclopropanols. CHEM[J]. 2020, 6(9): 2407-2419, http://dx.doi.org/10.1016/j.chempr.2020.07.003.
[14] Liu, Xiaojian, Hou, Chuanqi, Peng, Yiyuan, Chen, Pinhong, Liu, Guosheng. Ligand-Controlled Regioselective Pd-Catalyzed Diamination of Alkenes. ORGANIC LETTERS[J]. 2020, 22(23): 9371-9375, https://www.webofscience.com/wos/woscc/full-record/WOS:000598141000044.
[15] Fu, Liang, Zhang, Zhihan, Chen, Pinhong, Lin, Zhenyang, Liu, Guosheng. Enantioselective Copper-Catalyzed Alkynylation of Benzylic C-H Bonds via Radical Relay. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2020, 142(28): 12493-12500, https://www.webofscience.com/wos/woscc/full-record/WOS:000551495700065.
[16] Hou, Chuanqi, Chen, Pinhong, Liu, Guosheng. Enantioselective Palladium(II)-Catalyzed Oxidative Aminofluorination of Unactivated Alkenes with Et4NF.3 HF as a Fluoride Source. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2020, 59(7): 2735-2739, https://www.webofscience.com/wos/woscc/full-record/WOS:000504784200001.
[17] Chen, Chaohuang, Pflueger, Philipp Miro, Chen, Pinhong, Liu, Guosheng. Palladium(II)-Catalyzed Enantioselective Aminotrifluoromethoxylation of Unactivated Alkenes using CsOCF3 as a Trifluoromethoxide Source. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 58(8): 2392-2396, http://dx.doi.org/10.1002/anie.201813591.
[18] Wu, Lianqian, Wang, Fei, Chen, Pinhong, Liu, Guosheng. Enantioselective Construction of Quaternary All-Carbon Centers via Copper-Catalyzed Arylation of Tertiary Carbon-Centered Radicals. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2019, 141(5): 1887-1892,
[19] Cheng Zhongming, Chen Pinhong, Liu Guosheng. Enantioselective Cyanation of Remote C-H Bonds via Cooperative Photoredox and Copper Catalysis. ACTA CHIMICA SINICA[J]. 2019, 77(9): 856-860, http://dx.doi.org/10.6023/A19070252.
[20] Li, Xiaonan, Chen, Pinhong, Liu, Guosheng. Iodine(III) reagent (ABX-N-3)-induced intermolecular anti-Markovnikov hydroazidation of unactivated alkenes. SCIENCE CHINA-CHEMISTRY[J]. 2019, 62(11): 1537-1541, https://www.webofscience.com/wos/woscc/full-record/WOS:000491830300001.
[21] Zhang, Guoyu, Fu, Liang, Chen, Pinhong, Zou, Jianping, Liu, Guosheng. Proton-Coupled Electron Transfer Enables Tandem Radical Relay for Asymmetric Copper-Catalyzed Phosphinoylcyanation of Styrenes. ORGANIC LETTERS[J]. 2019, 21(13): 5015-5020,
[22] Zhang, Wen, Wu, Lianqian, Chen, Pinhong, Liu, Guosheng. Enantioselective Arylation of Benzylic C-H Bonds by Copper-Catalyzed Radical Relay. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2019, 58(19): 6425-6429, https://www.webofscience.com/wos/woscc/full-record/WOS:000471976400052.
[23] Li, Jiayuan, Zhang, Zhihan, Wu, Lianqian, Zhang, Wen, Chen, Pinhong, Lin, Zhenyang, Liu, Guosheng. Site-specific allylic C-H bond functionalization with a copper-bound N-centred radical. NATURE[J]. 2019, 574(7779): 516-+,
[24] Fu, Liang, Zhou, Song, Wan, Xiaolong, Chen, Pinhong, Liu, Guosheng. Enantioselective Trifluoromethylalkynylation of Alkenes via Copper-Catalyzed Radical Relay. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2018, 140(35): 10965-10969, https://www.webofscience.com/wos/woscc/full-record/WOS:000444219100009.
[25] Wang, Fei, Wang, Dinghai, Zhou, Yu, Liang, Ling, Lu, Ronghua, Chen, Pinhong, Lin, Zhenyang, Liu, Guosheng. Divergent Synthesis of CF3-Substituted Allenyl Nitriles by Ligand-Controlled Radical 1,2-and 1,4-Addition to 1,3-Enynes. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2018, 57(24): 7140-7145, https://www.webofscience.com/wos/woscc/full-record/WOS:000434350400029.
[26] Zhang, Hao, Wang, HaoYang, Luo, Yixin, Chen, Chaohuang, Cao, Yimiao, Chen, Pinhong, Guo, YinLong, Lan, Yu, Liu, Guosheng. Regioselective Palladium-Catalyzed C-H Bond Trifluoroethylation of Indoles: Exploration and Mechanistic Insight. ACS CATALYSIS[J]. 2018, 8(3): 2173-2180, https://www.webofscience.com/wos/woscc/full-record/WOS:000426804100060.
[27] Chen, Chaohuang, Luo, Yixin, Fu, Liang, Chen, Pinhong, Lan, Yu, Liu, Guosheng. Palladium-Catalyzed Intermolecular Ditrifluoromethoxylation of Unactivated Alkenes: CF3O-Palladation Initiated by Pd(IV). JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2018, 140(4): 1207-1210, https://www.webofscience.com/wos/woscc/full-record/WOS:000424313000005.
[28] Li, Xiang, Chen, Pinhong, Liu, Guosheng. Recent advances in hypervalent iodine(III)-catalyzed functionalization of alkenes. BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY[J]. 2018, 14(1): 1813-1825, https://doaj.org/article/b94fdc1cdf504d96bf685a8f25b67b37.
[29] Wang, Fei, Chen, Pinhong, Liu, Guosheng. Copper-Catalyzed Radical Relay for Asymmetric Radical Transformations. ACCOUNTS OF CHEMICAL RESEARCHnull. 2018, 51(9): 2036-2046, https://www.webofscience.com/wos/woscc/full-record/WOS:000445441200016.
[30] Dinghai Wang, Zheliang Yuan, Qilun Liu, Pinhong Chen, Guosheng Liu. Decarboxylative Fluorination of Arylcarboxylic Acids Promoted by ortho-Hydroxy and Amino Groups. 中国化学：英文版[J]. 2018, 36(6): 507-514, http://lib.cqvip.com/Qikan/Article/Detail?id=675458235.
[31] Zhang, Zuxiao, Chen, Pinhong, Liu, Guosheng. Copper-mediated intramolecular aminofluorination of 1,3-dienes by using nucleophilic fluorine reagents. CHEMICAL COMMUNICATIONS[J]. 2018, 54(63): 8709-8712,
[32] Qi, Xiaoxu, Chen, Chaohuang, Hou, Chuanqi, Fu, Liang, Chen, Pinhong, Liu, Guosheng. Enantioselective Pd(II)-Catalyzed Intramolecular Oxidative 6-endo Aminoacetoxylation of Unactivated Alkenes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2018, 140(24): 7415-7419, https://www.webofscience.com/wos/woscc/full-record/WOS:000436211600011.
[33] 刘国生. Pd-Catalyzed Intermolecular Arylcarbonylation of Unactivated Alkenes: Incorporation of Bulky Aryls at Room Temperature.. Angew. Chem. Int. Ed.. 2018,
[34] Wang, Dinghai, Zhu, Na, Chen, Pinhong, Lin, Zhenyang, Liu, Guosheng. Enantioselective Decarboxylative Cyanation Employing Cooperative Photoredox Catalysis and Copper Catalysis. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2017, 139(44): 15632-15635, https://www.webofscience.com/wos/woscc/full-record/WOS:000415028200020.
[35] Wang, Dinghai, Wang, Fei, Chen, Pinghong, Lin, Zhenyang, Liu, Guosheng. Enantioselective Copper-Catalyzed Intermolecular Amino- and Azidocyanation of Alkenes in a Radical Process. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2017, 56(8): 2054-2058, https://www.webofscience.com/wos/woscc/full-record/WOS:000397323300013.
[36] Chen, Chaohuang, Fu, Liang, Chen, Pinhong, Liu, Guosheng. Recent Advances and Perspectives of Transition Metal-Catalyzed Asymmetric Fluorination Reactions. CHINESE JOURNAL OF CHEMISTRY[J]. 2017, 35(12): 1781-1788, http://lib.cqvip.com/Qikan/Article/Detail?id=674615873.
[37] Li, Ming, Yu, Feng, Chen, Pinhong, Liu, Guosheng. Palladium-Catalyzed Intermolecular Azidocarbonylation of Alkenes via a Cooperative Strategy. JOURNAL OF ORGANIC CHEMISTRY[J]. 2017, 82(22): 11682-11690, https://www.webofscience.com/wos/woscc/full-record/WOS:000416204400003.
[38] Zhang, Wen, Chen, Pinhong, Liu, Guosheng. Copper-Catalyzed Arylation of Benzylic C-H bonds with Alkylarenes as the Limiting Reagents. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2017, 139(23): 7709-7712, https://www.webofscience.com/wos/woscc/full-record/WOS:000403631200010.
[39] Peng, Haihui, Yuan, Zheliang, Chen, Pinhong, Liu, Guosheng. Palladium-Catalyzed Intermolecular Oxidative Diazidation of Alkenes. CHINESE JOURNAL OF CHEMISTRY[J]. 2017, 35(6): 876-880, http://lib.cqvip.com/Qikan/Article/Detail?id=673296498.
[40] Wang, Fei, Liu, Guosheng. Setting Cyclohexane Stereochemistry with Oxidation. ACS CENTRAL SCIENCE[J]. 2017, 3(3): 161-162, https://doaj.org/article/91b89774f49a4316b05293c4947d8c33.
[41] Wang, Dinghai, Wu, Lianqian, Wang, Fei, Wan, Xiaolong, Chen, Pinhong, Lin, Zhenyang, Liu, Guosheng. Asymmetric Copper-Catalyzed Intermolecular Aminoarylation of Styrenes: Efficient Access to Optical 2,2-Diarylethylamines. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2017, 139(20): 6811-6814, https://www.webofscience.com/wos/woscc/full-record/WOS:000402498500008.
[42] Qi, Xiaoxu, Chen, Pinhong, Liu, Guosheng. Catalytic Oxidative Trifluoromethoxylation of Allylic C-H Bonds Using a Palladium Catalyst. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2017, 56(32): 9517-9521, https://www.webofscience.com/wos/woscc/full-record/WOS:000406385200050.
[43] Wu, Lianqian, Wang, Fei, Wan, Xiaolong, Wang, Dinghai, Chen, Pinhong, Liu, Guosheng. Asymmetric Cu-Catalyzed Intermolecular Trifluoromethylarylation of Styrenes: Enantioselective Arylation of Benzylic Radicals. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2017, 139(8): 2904-2907, https://www.webofscience.com/wos/woscc/full-record/WOS:000395493400012.
[44] Qi, Xiaoxu, Yu, Feng, Chen, Pinhong, Liu, Guosheng. Intermolecular Palladium-Catalyzed Oxidative Fluorocarbonylation of Unactivated Alkenes: Efficient Access to beta-Fluorocarboxylic Esters. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2017, 56(41): 12692-12696, https://www.webofscience.com/wos/woscc/full-record/WOS:000411810600051.
[45] Zhang, Wen, Chen, Pinhong, Liu, Guosheng. Enantioselective Palladium(II)-Catalyzed Intramolecular Aminoarylation of Alkenes by Dual N-H and Aryl C-H Bond Cleavage. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2017, 56(19): 5336-5340, https://www.webofscience.com/wos/woscc/full-record/WOS:000399951200032.
[46] 刘国生. Cooperative Strategy for the Highly Selective Intermolecular Oxycarbonylation Reaction of Alkenes using palladium catalyst.. Angew. Chem. Int. Ed.. 2016,
[47] Xu, Tao, Wu, Yichen, Yuan, Zheliang, Guan, Hairong, Liu, Guosheng. Mechanistic Investigation on the Silver-Catalyzed Oxidative Intramolecular Aminofluorination of Alkynes. ORGANOMETALLICS[J]. 2016, 35(10): 1347-1349, https://www.webofscience.com/wos/woscc/full-record/WOS:000376548400003.
[48] Wang, Fei, Wang, Dinghai, Wan, Xiaolong, Wu, Lianqian, Chen, Pinhong, Liu, Guosheng. Enantioselective Copper-Catalyzed Intermolecular Cyanotrifluoromethylation of Alkenes via Radical Process. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2016, 138(48): 15547-15550, https://www.webofscience.com/wos/woscc/full-record/WOS:000389623800011.
[49] Zhang, Wen, Wang, Fei, McCann, Scott D, Wang, Dinghai, Chen, Pinhong, Stahl, Shannon S, Liu, Guosheng. Enantioselective cyanation of benzylic C-H bonds via copper-catalyzed radical relay. SCIENCE[J]. 2016, 353(6303): 1014-1018, http://www.corc.org.cn/handle/1471x/2375639.
[50] Yuan, Zheliang, Cheng, Ran, Chen, Pinhong, Liu, Guosheng, Liang, Steven H. Efficient Pathway for the Preparation of Aryl(isoquinoline)iodonium-(III) Salts and Synthesis of Radiofluorinated Isoquinolines. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2016, 55(39): 11882-11886, https://www.webofscience.com/wos/woscc/full-record/WOS:000384713100030.
[51] Wu, Liang, Chen, Pinhong, Liu, Guosheng. Pd(II)-Catalyzed Aminofluorination of Alkenes in Total Synthesis 6-(R)-Fluoroswainsonine and 5-(R)-Fluorofebrifugine. ORGANIC LETTERS[J]. 2016, 18(5): 960-963, https://www.webofscience.com/wos/woscc/full-record/WOS:000371754000019.
[52] Yin, Guoyin, Mu, Xin, Liu, Guosheng. Palladium(II)-Catalyzed Oxidative Difunctionalization of Alkenes: Bond Forming at a High-Valent Palladium Center. ACCOUNTS OF CHEMICAL RESEARCHnull. 2016, 49(11): 2413-2423, https://www.webofscience.com/wos/woscc/full-record/WOS:000388154800006.
[53] 刘国生. Aminofluroination of Alkenes: Efficient synthesis of Fluorinated Alkylamine and Heterocycles. Eur. J. Org. Chem.. 2015,
[54] 刘国生. Copper-catalyzed Intermolecualr Trifluoromethylthiocynation of Alkene. Org. Lett. 2015,
[55] Liu, Qilun, Yuan, Zheliang, Wang, Haoyang, Li, Yang, Wu, Yichen, Xu, Tao, Leng, Xuebing, Chen, Pinhong, Guo, Yinlong, Lin, Zhenyang, Liu, Guosheng. Abnormal Mesoionic Carbene Silver Complex: Synthesis, Reactivity, and Mechanistic Insight on Oxidative Fluorination. ACS Catalysis[J]. 2015, 5(11): 6732-6737, https://www.webofscience.com/wos/woscc/full-record/WOS:000364441300061.
[56] 刘国生. Copper-catalyzed Trifluoromethylation of Alkynes: Efficient Synthesis of CF3-substituted Azirines. Angew. Chem. Int. Ed. 2015,
[57] 刘国生. High Highly Selective Pd-Catalyzed Intermolecular Fluorosulfonylation of Styrenes. J. Am. Chem. Soc. 2015,
[58] 刘国生. Pd-catalyzed Intermolecular Enantioselective Hydroamination of Styrenes coupled with Alcohol Oxidation. Org Chem Front. 2015,
[59] 刘国生. Copper-catalyzed Intermolecualr Cyano- and Thiotrifluoromethylthiocynation of Allenes. Org. Lett. 2015,
[60] Chen, Chaohuang, Chen, Pinhong, Liu, Guosheng. Palladium-Catalyzed Intramolecular Aminotrifluoromethoxylation of Alkenes. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2015, 137(50): 15648-15651, https://www.webofscience.com/wos/woscc/full-record/WOS:000367562800014.
[61] Cheng, Jiashun, Qi, Xiaoxu, Li, Ming, Chen, Pinhong, Liu, Guosheng. Palladium-Catalyzed Intermolecular Aminocarbonylation of Alkenes: Efficient Access of beta-Amino Acid Derivatives. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2015, 137(7): 2480-2483, https://www.webofscience.com/wos/woscc/full-record/WOS:000350192700018.
[62] 刘国生. Palladium-Catalyzed Tandem Cyclization for the efficient synthesis of Spiro O,N-Acetals. Org. chem. Front.. 2014,
[63] 刘国生. Site-Selective Palladium-Catalyzed Arene C-H trifluoroethylation of Aryl iodide. Angew. Chem. Int. Ed. 2014,
[64] 刘国生. Branch-selective Allylic C-H Caboxylation of Terminal Alkenes by Pd/Sox Catalyst. Org. Lett. 2014,
[65] 刘国生. Palladium-catalyzed Aminohydroxylation of Alkenes: Hydrogen Peroxide as Oxidant and Water as Nucleophile. J. Am. Chem. Soc. 2014,
[66] 刘国生. Copper-Catalyzed Thiotrifluoromethylation of Aryl Bromide. Org. Lett. 2014,
[67] 刘国生. Copper-catalyzed azidotrifluoromethylation of Alkenes: Convenient Access to CF3-containing Alkyl Azides. Angew. Chem. Int. Ed. 2014,
[68] 刘国生. Copper-catalyzed Intermolecular Aryltrifluoromethylation of Alkenes. J. Am. Chem. Soc. 2014,
[69] 刘国生. Copper-Catalyzed Three Component Coupling: Efficient Access of CF3-Containing Alkyl Nitriles. J. Fluorine Chem. 2014,
[70] Mu Xin, Zhang Hao, Chen Pinhong, Liu Guosheng. Copper-catalyzed fluorination of 2-pyridyl aryl bromides. Chem. Sci.[J]. 2014, 5(1): 275-280, http://ir.sioc.ac.cn/handle/331003/38996.
[71] 刘国生. Copper-mediated/-catalyzed fluorination of arenes. Org. chem. Front.. 2014,
[72] 刘国生. Recent Advance on the Transition Metal-Catalyzed Trifluoromethylation and Related Transformations. Synthesis. 2013,
[73] 刘国生. Palladium-catalyzed Arylakylation of Unactivated Alkenes: Pyridine Promote C-H Acitivation. Synlett. 2013,
[74] Wu Tao, Cheng Jiashun, Chen Pinhong, Liu Guosheng. Regioselective palladium-catalyzed intramolecular oxidative aminofluorination of unactivated alkenes. Chem. Commun.[J]. 2013, 49(77): 8707-8709, http://www.irgrid.ac.cn/handle/1471x/848170.
[75] Claudio Martnez, Yichen Wu, Adam B Weinstein, Shannon S Stahl, Guosheng Liu, Kilian Muiz. Palladium Catalyzed Intermolecular Aminoacetoxylation of Alkenes and the Influence of PhI(OAc) 2 on Aminopalladation Stereoselectivity. The Journal of organic chemistry. 2013, 78(12): 6309-6315,
[76] Liu, Qilun, Chen, Pinhong, Liu, Guosheng. Palladium-Catalyzed C-C Triple Bond Cleavage: Efficient Synthesis of 4H-Benzod1,3oxazin-4-ones. ACS CATALYSIS[J]. 2013, 3(2): 178-181, http://www.irgrid.ac.cn/handle/1471x/848168.
[77] 刘国生. Silver-catalyzed tandem Aminofluorination and Trifluoromethylation of Alkynes. Org. Lett.. 2013,
[78] Zhang, Zuxiao, Wang, Fei, Mu, Xin, Chen, Pinhong, Liu, Guosheng. Copper-Catalyzed Regioselective Fluorination of Allylic Halides. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2013, 52(29): 7549-7553, http://www.irgrid.ac.cn/handle/1471x/848181.
[79] PENG HAIHUI, YUAN ZHELIANG, Wang Haoyang, Guo Yinlong, Liu Guosheng. Palladium-catalyzed intermolecular fluoroesterification of styrenes: exploration and mechanistic insight. Chem. Sci.[J]. 2013, 4(8): 3172-3178, http://www.irgrid.ac.cn/handle/1471x/848169.
[80] Wu, Tao, Zhang, Hao, Liu, Guosheng. Organocatalyzed arylalkylation of activated alkenes via decarboxylation of PhI(O2CR)(2): efficient synthesis of oxindoles. TETRAHEDRON[J]. 2012, 68(26): 5229-5233, http://dx.doi.org/10.1016/j.tet.2012.03.051.
[81] Mu Xin, Wu Tao, Wang Haoyang, Guo Yinlong, Liu Guosheng. Palladium-Catalyzed Oxidative Aryltrifluoromethylation of Activated Alkenes at Room Temperature. J. Am. Chem. Soc.[J]. 2012, 134(2): 878-881, http://www.irgrid.ac.cn/handle/1471x/682055.
[82] Yin, Guoyin, Wu, Tao, Liu, Guosheng. Highly Selective Palladium-Catalyzed Intramolecular Chloroamination of Unactivated Alkenes by Using Hydrogen Peroxide as an Oxidant. CHEMISTRY-A EUROPEAN JOURNAL[J]. 2012, 18(2): 451-455, http://www.irgrid.ac.cn/handle/1471x/682082.
[83] 刘国生. A Concise and Selective Synthesis of 4-Fluoroisoquinolines and 4-Fluoropyrrolo[a]isoquinolines: Silver-Catalyzed Fluroination of Alkynes. Org. Lett. 2012,
[84] 刘国生. Transition Metal-Catalyzed Fluorination of Unsaturated Carbon-Carbon Multibonds: A New Strategy for Fluorinated Heterocycles Synthesis. Org. Biomol. Chem.. 2012,
[85] 徐涛, 邱水发, 刘国生. Palladium-catalyzed inter- and intramolecular hydroamination of styrenes coupled with alcohol oxidation using N-fluorobenzenesulfonimide as the oxidant. J. Organomet. Chem.[J]. 2011, 696(1): 46-49, http://dx.doi.org/10.1016/j.jorganchem.2010.07.015.
[86] Chen, Shujun, Wu, Tao, Liu, Guosheng, Zhen, Xingliang. Highly Selective Palladium-Catalyzed Intramolecular Aminonitroxylation of Alkenes. SYNLETT[J]. 2011, 891-894, http://www.irgrid.ac.cn/handle/1471x/681986.
[87] 慕欣, 陈淑君, 郑兴良, 刘国生. Palladium-Catalyzed Oxidative Trifluoromethylation of Indoles at Room Temperature. Chem.-Eur. J.[J]. 2011, 17(22): 6039-6042, http://www.irgrid.ac.cn/handle/1471x/681982.
[88] 吴涛, 慕欣, 刘国生. Palladium-Catalyzed Oxidative Arylalkylation of Activated Alkenes: Dual C?H Bond Cleavage of an Arene and Acetonitrile. Angew. Chem.-Int. Edit.[J]. 2011, 50(52): 12578-12581, http://www.irgrid.ac.cn/handle/1471x/681999.
[89] 徐涛, 慕欣, 彭海辉, 刘国生. Silver-Catalyzed Intramolecular Aminofluorination of Activated Allenes. Angew. Chem.-Int. Edit.[J]. 2011, 50(35): 8176-8179, http://www.irgrid.ac.cn/handle/1471x/681993.
[90] 彭海辉, 刘国生. Palladium-Catalyzed Tandem Fluorination and Cyclization of Enynes. Org. Lett.[J]. 2011, 13(4): 772-775, http://www.irgrid.ac.cn/handle/1471x/681981.
[91] 邱水发, 徐涛, 周娟, 郭寅龙, 刘国生. Palladium-Catalyzed Intermolecular Aminofluorination of Styrenes. J. Am. Chem. Soc.[J]. 2010, 132(9): 2856-2857, http://www.irgrid.ac.cn/handle/1471x/587655.
[92] Liu, Guosheng, Wu, Yichen, Yu, JQ, Shi, Z. Palladium-Catalyzed Allylic C-H Bond Functionalization of Olefins. C-H ACTIVATION[J]. 2010, 292: 195-209, http://www.irgrid.ac.cn/handle/1471x/681978.
[93] 阴国印, 吴奕晨, 刘国生. Scope and Mechanism of Allylic C-H Amination of Terminal Alkenes by the Palladium/PhI(OPiv)(2) Catalyst System: Insights into the Effect of Naphthoquinone. J. Am. Chem. Soc.[J]. 2010, 132(34): 11978-11987, http://www.irgrid.ac.cn/handle/1471x/681977.
[94] 吴涛, 阴国印, 刘国生. Palladium-Catalyzed Intramolecular Aminofluorination of Unactivated Alkenes. J. Am. Chem. Soc.[J]. 2009, 131(45): 16354-16355, http://www.irgrid.ac.cn/handle/1471x/681971.
[95] 邱水发, 魏运洋, 刘国生. Palladium-Catalyzed Intramolecular Hydroamination of Allenes Coupled to Aerobic Alcohol Oxidation. Chem.-Eur. J.[J]. 2009, 15(12): 2751-2754, http://www.irgrid.ac.cn/handle/1471x/681976.
[96] 吴亮, 邱水发, 刘国生. Bronsted Base-Modulated Regioselective Pd-Catalyzed Intramolecular Aerobic Oxidative Amination of Alkenes: Formation of Seven-Membered Amides and Evidence for Allylic C-H Activation. Org. Lett.[J]. 2009, 11(12): 2707-2710, http://www.irgrid.ac.cn/handle/1471x/681974.
[97] Liu, Guosheng, Yin, Guoyin, Wu, Liang. Palladium-catalyzed intermolecular aerobic oxidative amination of terminal alkenes: Efficient synthesis of linear allylamine derivatives. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2008, 47(25): 4733-4736, http://www.irgrid.ac.cn/handle/1471x/670678.
[98] 刘国生. Palladium-catalyzed oxidative cyclization of enyne with hydrogen peroxide as the oxidant. Angew. Chem. Int. Ed.. 2008,
指导学生
已指导学生
阴国印 博士研究生 070303-有机化学
吴亮 博士研究生 070303-有机化学
徐涛 博士研究生 070303-有机化学
吴涛 博士研究生 070303-有机化学
张祖骁 硕士研究生 070303-有机化学
慕欣 博士研究生 070303-有机化学
彭海辉 博士研究生 070303-有机化学
刘启伦 博士研究生 070303-有机化学
朱海涛 博士研究生 070303-有机化学
程家顺 博士研究生 070303-有机化学
张浩 博士研究生 070303-有机化学
王飞 博士研究生 070303-有机化学
袁浙梁 博士研究生 070303-有机化学
陈朝煌 博士研究生 070303-有机化学
梁兆利 博士研究生 070303-有机化学
亓晓旭 博士研究生 070303-有机化学
李明 博士研究生 070303-有机化学
张文 博士研究生 070303-有机化学
侯传崎 博士研究生 070303-有机化学
吴联谦 博士研究生 070303-有机化学
李响 博士研究生 070303-有机化学
庄炜文 硕士研究生 070303-有机化学
李家圆 博士研究生 070303-有机化学
蒋超 博士研究生 070303-有机化学
现指导学生
杨新拓 博士研究生 070303-有机化学
李笑男 博士研究生 070303-有机化学
陆荣华 博士研究生 070303-有机化学
张洪刚 博士研究生 070303-有机化学
赵雪垚 硕士研究生 070303-有机化学
金剑波 硕士研究生 070303-有机化学
徐品 博士研究生 070303-有机化学
吴金贵 硕士研究生 070303-有机化学
张方家 硕士研究生 070303-有机化学
樊文峥 博士研究生 070303-有机化学
成忠明 博士研究生 070303-有机化学