General

Yulei Chang, Professor, PhD Supervisor, PI

State Key Laboratory of Luminescence and Applications, Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences

Email: yuleichang@ciomp.ac.cn

Address: No. 3888, Southeast Lake Road, Changchun

Postal Code: 130033

Website:

Research Areas

Luminescent Materials, Physics and  Devices

We have a solid theoretical foundation and rich work experience in the fields of elemental excitation in condensed matter, luminescence dynamics in condensed matter, photoelectron materials and devices, interactions between light and biomolecules in biological systems, and Förster resonance energy transfer. It has research characteristics and advantages in rare earth luminescent materials, physics, biophotonics, and other research directions.


Admission Information

Desired backgrounds include: 

• Rare Earth (lanthanide) doped luminescent materials and physics

• Biophotonics: NIR-II fluorescence imaging/phototherapy/Biosensing,

• Surface modification of nanoparticles

• Dynamic regulation of luminescence: Ferroelectric/Magneto-Optical Modulation

• Simulation of Luminescence Process: Monte Carlo and other methods


Publications

   
Representative Papers (*corresponding author)

[1] Y. Chang*, H. Chen, X. Xie, Y. Wan, Q. Li, F. Wu, R. Yang, W. Wang, X. Kong, Bright Tm3+-based downshifting luminescence nanoprobe operating around 1800 nm for NIR-IIb and c bioimaging, Nature communications 14(1) (2023) 1079.

[2] Q.Q. Li, X.Y. Xie, H. Wu, H.R. Chen, W. Wang, X.G. Kong, Y.L. Chang*, Superenhancement Photon Upconversion Nanoparticles for Photoactivated Nanocryometer, Nano letters 23(8) (2023) 3444-3450.

[3] X. Xie, Q. Li, H. Chen, W. Wang, F. Wu, L. Tu, Y. Zhang, X. Kong, Y. Chang*, Manipulating the Injected Energy Flux via Host-Sensitized Nanostructure for Improving Multiphoton Upconversion Luminescence of Tm3+, Nano letters 22(13) (2022) 5339-5347.

[4] F.X. Wu, H.R. Chen, Q.Q. Li, R.Q. Liu, Y.K. Suo, B. Li, X.G. Kong, Z. Cheng, H.G. Liu*, Y.L. Chang*, Amplifying oxidative stress utilizing multiband luminescence of lanthanide nanoparticles for eliciting systemic antitumor immunity, Chemical Engineering Journal 468 (2023).

[5] X. Dai, Y. Liu, F. Meng, Q. Li, F. Wu, J. Yuan, H. Chen, H. Lv, Y. Zhou*, Y. Chang*, Amplification of oxidative damage using near-infrared II-mediated photothermal/thermocatalytic effects for periodontitis treatment, Acta biomaterialia 171 (2023) 519-531.

[6] F. Wu, H. Chen, R. Liu, Y. Suo, Q. Li, Y. Zhang, H. Liu, Z. Cheng*, Y. Chang*, Modulation of the Tumor Immune Microenvironment by Bi2Te3-Au/Pd-Based Theranostic Nanocatalysts Enables Efficient Cancer Therapy, Advanced healthcare materials 11(19) (2022) e2200809.

[7] H. Chen, F. Wu, X. Xie, W. Wang, Q. Li, L. Tu, B. Li, X. Kong, Y. Chang*, Hybrid Nanoplatform: Enabling a Precise Antitumor Strategy via Dual-Modal Imaging-Guided Photodynamic/Chemo-/Immunosynergistic Therapy, ACS Nano 15(12) (2021) 20643-20655.

[8] Y. Feng, H. Chen, Y. Wu, I. Que, F. Tamburini, F. Baldazzi, Y. Chang*, H. Zhang*, Optical imaging and pH-awakening therapy of deep tissue cancer based on specific upconversion nanophotosensitizers, Biomaterials 230 (2020) 119637.

[9] Y. Feng, Y. Wu, J. Zuo, L. Tu, I. Que, Y. Chang*, L.J. Cruz, A. Chan, H. Zhang*, Assembly of upconversion nanophotosensitizer in vivo to achieve scatheless real-time imaging and selective photodynamic therapy, Biomaterials 201 (2019) 33-41.

[10] J. Zuo, L. Tu, Q. Li, Y. Feng, I. Que, Y. Zhang, X. Liu, B. Xue, L.J. Cruz, Y. Chang*, H. Zhang*, X. Kong*, Near Infrared Light Sensitive Ultraviolet-Blue Nanophotoswitch for Imaging-Guided "Off-On" Therapy, ACS Nano 12(4) (2018) 3217-3225.