Young Professor, Doctoral Supervisor, Distinguished Young Scholar of Guangdong Province, and Member of the Youth Innovation Association of the Chinese Academy of Sciences (CAS), Overseas High-Level Talent of Shenzhen City. He joined the Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences in July 2014. He received his PhD from the University of Chinese Academy of Sciences, during which he worked in the research group of Professor Sessler, Member of the US National Academy of Sciences and Foreign Member of the Chinese Academy of Sciences, focusing on molecular probes. He has long been committed to addressing key scientific issues in the field of diagnosis and treatment of refractory major diseases, developing innovative acoustic and optical imaging technologies and probes to monitor and quantify key disease-related molecules, cells, and tissues with high resolution and high sensitivity, and exploring the laws of their cross-scale interaction behaviors.
To date, his research achievements have been published as first/corresponding (including co-first/co-corresponding) author in journals such as PNAS, Nature Communications, Light: Science & Applications, JACS, Cell Reports Medicine, and Photoacoustics. He has been granted 7 authorized patents. He presides over 7 projects including the National Natural Science Foundation of China and the Natural Science Foundation of Guangdong Province - Distinguished Young Scholar Fund, and has been a core participant in more than 10 national and provincial-level projects, including the National Key Research and Development Program, the CAS Instrument Development Project, and provincial and municipal natural science funds. He is elected as a Young Member of the Biomedical Photonics Professional Committee of the Chinese Optical Society and serves as an Invited Editor for flagship optical SCI journals such as JIOHS (Journal of Innovative Optical Health Sciences).
Webpage
Google scholar homepage:
https://scholar.google.com/citations?user=JSD99uoAAAAJ&hl=zh-CN&oi=ao
Research center:
https://bmo.siat.ac.cn/
Publications
Representive Publications (More: https://scholar.google.com/citations?user=JSD99uoAAAAJ&hl=zh-CN&oi=ao)
1. Jianhai Chen, Silue Zeng, Qiang Xue, Yuchuan Hong, Liangjian Liu, Liang Song, Chihua Fang, Hai Zhang, Benguo Wang, Adam C. Sedgwick, Peng Zhang, Jonathan L Sessler*, Chengbo Liu*, and Jingqin Chen*. Photoacoustic Image-guided Biomimetic Nanoparticles Targeting Rheumatoid Arthritis. Proceedings of the National Academy of Sciences, 2022, 119 (43) e2213373119
2. Jianhai Chen#, Jianwei Tan#, Nannan Wang, Hui Li, Wenxiang Cheng, Jian Li, Benguo Wang, Adam C. Sedgwick, Zhitong Chen, Guojun Chen, Peng Zhang*, Wei Zheng, Chengbo Liu*, and Jingqin Chen*. Specific macrophage RhoA targeting CRISPR-Cas9 for mitigating osteoclastogenesis-induced joint damage in inflammatory arthritis, Cell Reports Medicine, 2025, 6(4), 102046
3. Jingqin Chen*#, Rui Chen#, Calvin V. Chau#, Adam C. Sedgwick#, Qiang Xue, Tao Chen, Silue Zeng, Ningbo Chen, Kenneth K. Y. Wong, Liang Song, Yaguang Ren*, Jian Yang*, Jonathan L. Sessler*, and Chengbo Liu*. Targeted Cyclo[8]pyrrole-based NIR-II Photoacoustic Tomography Probe for Suppression of Orthotopic Pancreatic Tumor Growth and Intra-abdominal Metastases. Journal of the American Chemical Society, 2024, 146, 7, 4620–4631
4. Silue Zeng#, Jingqin Chen#*, Yaguang Ren, Jianyou Gu, Junfeng Zhang, Liangjian Liu, Zhiqiang Xu, Rui Chen, Chuanyu Tang, Qiang Xue, Sai Wen, Haoyu Hu, Zheng Liu, Ning Ren, Chihua Fang*, Chengbo Liu*. Multiscale imaging on proton pump-driven acidity for assessing tumor progression and metastasis, Nature Communications, 2026, 17, 1785
5. Chuanyu Tang, Cheng He, Decheng Wang, Jie Guo, Xiangyi Yin, Hanjie Ye, Lei Wu, Yuling Zhang, Silue Zeng, Xiaojun Zeng, Chengbo Liu*, Jingqin Chen*, Chihua Fang*. Co-delivery of sorafenib and an FSP1 inhibitor triggers dual ferroptosis in tumor cells and immunosuppressive macrophages for enhanced immunotherapy in mouse models of hepatocellular carcinoma. Nature Communications, 2025, 16, 10096
6. Mengtao Han#, Mengchen Yu#, Nanlin You, Yaguang Ren, Zhiqiang Xu, Zhifeng Wu, Yiming He, Tao Sun, Zhiwei Xue, Chengbo Liu*, Donghai Wang* and Jingqin Chen*. Rapid Synergistic Thrombolysis of Ischemic Stroke Guided by High-Resolution and High-Speed Photoacoustic Cerebrovascular Imaging. Photoacoustics, 2025, 43, 100722
7. Qiang Xue#, Silue Zeng#, Yaguang Ren#, Yingying Pan#, Jianhai Chen, Ningbo Chen, Kenneth K. Y. Wong, Liang Song, Chihua Fang, Jinhan Guo, Jinfeng Xu, Chengbo Liu, Jie Zeng, Litao Sun*, Hai Zhang* and Jingqin Chen*. Relief of Tumor Hypoxia Using a Nanoenzyme Amplifies NIR-II Photoacoustic-Guided Photothermal Therapy. Biomedical Optics Express, 2024, 15, 59-76
8. Silue Zeng#，Jingqin Chen#*, Rongkang Gao#, Rui Chen, Qiang Xue, Yaguang Ren, Liangjian Liu, Chuanyu Tang, Haoyu Hu, Ning Zeng, Sai Wen, Hai Zhang, Chengbo Liu*, Chihua Fang*. NIR-II Photoacoustic Imaging-Guided Oxygen Delivery and Controlled Release Improves Photodynamic Therapy for Hepatocellular Carcinoma. Advanced Materials, 2024, 36(4):e2308780
9. Jingqin Chen#, Adam C. Sedgwick#, Sajal Sen#, Yaguang Ren, Qinchao Sun, Calvin Chau, Jonathan F. Arambula, Tridib Sarma*, Liang Song, Jonathan L. Sessler*, and Chengbo Liu*. Expanded porphyrins: Functional photoacoustic imaging agents that operate in the NIR-II region. Chemical Science, 2021, 12(29): 9916-9921.
10. Jingqin Chen#, Ji Qi#, Chao Chen#, Jianhai Chen, Liangjian Liu, Rongkang Gao, Tiantian Zhang, Liang Song, Dan Ding*, Peng Zhang*, and Chengbo Liu*. Tocilizumab-Conjugated Polymer Nanoparticles for NIR-II Photoacoustic Imaging-Guided Therapy of Rheumatoid Arthritis. Advanced Materials, 2020, 32(37):2003399.