基本信息
徐文忠  男  硕导  中国科学院植物研究所
电子邮件: xuwzh@ibcas.ac.cn
通信地址: 北京市海淀区香山路南辛村20号
邮政编码: 100093

研究领域

1、资源植物基因组编辑育种

以芍药科芍药属(牡丹和芍药)、小浆果(树莓、蓝莓、蓝靛果、黑加仑)、燕麦、木本油料作物(山桐子)、景天属(伴矿景天、东南景天)等野生资源和特色资源植物为研究材料,建立其组培快繁技术方法,构建其遗传转化技术平台,针对控制其重要的农艺性状、品质特性、环境适应性等相关的关键基因,进行基因组编辑育种,利用现代分子技术手段培育出高观赏价值、高营养价值、高抗逆性等新品种。 

2、植物吸收、转运重金属及信号应答的分子机理

以重金属(如镉、砷等)超积累植物和模式植物(水稻、拟南芥)为材料,利用分子生物学和生物信息学的研究手段和方法,挖掘和克隆植物转运重金属相关的重要基因,阐明重金属在植物个体及器官、组织、细胞中转移运输的分子机理,应用基因技术调控重金属在植物中的转运和积累;同时研究植物激素(如生长素、赤霉素、乙烯等)和myo-肌醇多磷酸信号在重金属逆境胁迫及其对植物生长发育影响中的作用和功能,揭示重金属对植物的毒害机理和植物细胞的应答机制及信号传导。

招生信息

   
招生专业
071008-发育生物学
招生方向
资源植物基因组编辑育种
植物对重金属胁迫应答的分子机制

教育背景

1999-09--中国科学院植物研究所   博士
1996-09--中国农业大学   硕士
1992-09--湖南农业大学   学士

工作经历

   
工作简历
2013-10~2014-09,美国Florida International University, 访问学者
2003-07~现在, 中国科学院植物研究所, 实习研究员、助理研究员、副研究员

教授课程

重要园艺性状品质形成与调控
花色花香遗传育种学

专利与奖励

   
专利成果
( 1 ) 一种与砷响应相关的调控片段及其应用, 发明, 2010, 第 1 作者, 专利号: ZL 201010128600.8
( 2 ) 一种检测植物中目标基因的方法及其专用SPR生物传感器, 发明, 2011, 第 3 作者, 专利号: 201110100899.0
( 3 ) 一种检测植物中目标蛋白的方法及其专用SPR生物传感器, 发明, 2011, 第 2 作者, 专利号: 201110081230.1
( 4 ) PvARRP1蛋白及其编码基因在砷转运解毒和积累中的应用, 发明, 2012, 第 1 作者, 专利号: 201210394041.4
( 5 ) 一种定性定量检测植物激素活性赤霉素的方法及其专用芯片, 发明, 2016, 第 1 作者, 专利号: 2013103816411
( 6 ) 一种景天属植物的遗传转化方法, 发明, 2019, 第 1 作者, 专利号: ZL201710205829.9

出版信息

   
发表论文
[1] Feng, ChengYong, Li, ShanShan, Taguchi, Goro, Wu, Qian, Yin, DanDan, Gu, ZhaoYu, Wu, Jie, Xu, WenZhong, Liu, Cheng, Wang, LiangSheng. Enzymatic basis for stepwise C-glycosylation in the formation of flavonoid di-C-glycosides in sacred lotus (Nelumbo nucifera Gaertn.). PLANT JOURNAL[J]. 2021, 106(2): 351-365, http://dx.doi.org/10.1111/tpj.15168.
[2] Zhao, Haixia, Wang, Liangsheng, Zhao, FangJie, Wu, Longhua, Liu, Anna, Xu, Wenzhong. SpHMA1 is a chloroplast cadmium exporter protecting photochemical reactions in the Cd hyperaccumulator Sedum plumbizincicola. PLANT CELL AND ENVIRONMENT[J]. 2019, 42(4): 1112-1124, https://www.webofscience.com/wos/woscc/full-record/WOS:000462360300003.
[3] 尹丹丹, 李珊珊, 吴倩, 冯成庸, 李冰, 王倩玉, 王亮生, 徐文忠. 我国6种主要木本油料作物的研究进展. 植物学报[J]. 2018, 53(1): 110-125, http://lib.cqvip.com/Qikan/Article/Detail?id=674503432.
[4] DanDan Yin, WenZhong Xu, QingYan Shu, ShanShan Li, Qian Wu, ChengYong Feng, ZhaoYu Gu, LiangSheng Wang. Fatty acid desaturase 3 (PsFAD3) from Paeonia suffruticosa reveals high α-linolenic acid accumulation. Plant Science[J]. 2018, 274: 212-222, http://dx.doi.org/10.1016/j.plantsci.2018.05.027.
[5] Yin, DanDan, Li, ShanShan, Shu, QingYan, Gu, ZhaoYu, Wu, Qian, Feng, ChengYong, Xu, WenZhong, Wang, LiangSheng. Identification of microRNAs and long non-coding RNAs involved in fatty acid biosynthesis in tree peony seeds. GENE[J]. 2018, 666: 72-82, http://dx.doi.org/10.1016/j.gene.2018.05.011.
[6] Liu, Huan, Zhao, Haixia, Wu, Longhua, Liu, Anna, Zhao, FangJie, Xu, Wenzhong. Heavy metal ATPase 3 (HMA3) confers cadmium hypertolerance on the cadmium/zinc hyperaccumulator Sedum plumbizincicola. NEW PHYTOLOGIST[J]. 2017, 215(2): 687-698, http://ir.ibcas.ac.cn/handle/2S10CLM1/13214.
[7] Wang, Bo, Du, Hong, Zhang, Zhennan, Xu, Wenzhong, Deng, Xin. BhbZIP60 from Resurrection Plant Boea hygrometrica Is an mRNA Splicing-Activated Endoplasmic Reticulum Stress Regulator Involved in Drought Tolerance. FRONTIERS IN PLANT SCIENCE[J]. 2017, 8: http://ir.ibcas.ac.cn/handle/2S10CLM1/13131.
[8] Liu, Huan, Zhao, Haixia, Wu, Longhua, Xu, Wenzhong. A Genetic Transformation Method for Cadmium Hyperaccumulator Sedum plumbizincicola and Non-hyperaccumulating Ecotype of Sedum alfredii. FRONTIERS IN PLANT SCIENCE[J]. 2017, 8: http://ir.ibcas.ac.cn/handle/2S10CLM1/13187.
[9] Li, Dongmei, Guo, Zhenpeng, Liu, Cuimei, Li, Jincheng, Xu, Wenzhong, Chen, Yi. Quantification of near-attomole gibberellins in floral organs dissected from a single Arabidopsis thaliana flower. PLANT JOURNAL[J]. 2017, 91(3): 547-557, http://ir.ibcas.ac.cn/handle/2S10CLM1/13205.
[10] 席红梅, 徐文忠, 麻密. 拟南芥双功能酶SAL1生物学功能的研究进展. 植物学报[J]. 2016, 51(3): 377-386, [11] Sun, YangYang, Xu, WenZhong, Wu, Li, Wang, RuoZhong, He, ZhenYan, Ma, Mi. An Arabidopsis mutant of inositol pentakisphosphate 2-kinase AtIPK1 displays reduced arsenate tolerance. PLANT CELL AND ENVIRONMENT[J]. 2016, 39(2): 416-426, http://ir.ibcas.ac.cn/handle/2S10CLM1/13349.
[12] Zhenyan He, Wenxiu Xu, Hua Xu, Hongmei Xi, Mi Ma, Wenzhong Xu. A SAL1 loss-of-function Arabidopsis mutant exhibits enhanced cadmium tolerance in association with alleviation of endoplasmic reticulum stress. Plant & Cell Physiology[J]. 2016, 57(6): 1210-1219, http://ir.ibcas.ac.cn/handle/2S10CLM1/12932.
[13] Dong, Hui, Xu, Wenzhong, Pillai, Jitesh K, Packianathan, Charles, Rosen, Barry P. High-throughput screening-compatible assays of As(III) S-adenosylmethionine methyltransferase activity. ANALYTICAL BIOCHEMISTRY[J]. 2015, 480: 67-73, http://dx.doi.org/10.1016/j.ab.2015.04.011.
[14] Zhao, Zhuoya, Xing, Zenan, Zhou, Min, Chen, Yi, Li, Chenzhong, Wang, Ruozhong, Xu, Wenzhong, Ma, Mi. Functional analysis of synthetic DELLA domain peptides and bioactive gibberellin assay using surface plasmon resonance technology. TALANTA[J]. 2015, 144(-): 502-509, http://dx.doi.org/10.1016/j.talanta.2015.06.069.
[15] Xu, Wenzhong, Dai, Wentao, Yan, Huili, Li, Sheng, Shen, Hongling, Chen, Yanshan, Xu, Hua, Sun, Yangyang, He, Zhenyan, Ma, Mi. Arabidopsis NIP3;1 Plays an Important Role in Arsenic Uptake and Root-to-Shoot Translocation under Arsenite Stress Conditions. MOLECULAR PLANT[J]. 2015, 8(5): 722-733, http://lib.cqvip.com/Qikan/Article/Detail?id=665028648.
[16] Zhao, Zhuoya, Chen, Yanshan, Xu, Wenzhong, Ma, Mi. Surface Plasmon Resonance Detection of Transgenic Cry1Ac Cotton (Gossypium spp.). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY[J]. 2013, 61(12): 2964-2969, http://ir.ibcas.ac.cn/handle/2S10CLM1/16155.
[17] Wenzhong Xu. Engineering arsenic tolerance and hyperaccumulation in plants for phytoremediation using a PvACR3 transgenic approach. Environmental Science and Technology. 2013, [18] 吴俐, 王若仲, 徐文忠. 拟南芥中myo-肌醇-多磷酸合成与代谢及其信号. 植物学报[J]. 2013, 48(1): 94-106, http://ir.ibcas.ac.cn/handle/2S10CLM1/16864.
[19] Guo, Jiangbo, Xu, Wenzhong, Ma, Mi. The assembly of metals chelation by thiols and vacuolar compartmentalization conferred increased tolerance to and accumulation of cadmium and arsenic in transgenic Arabidopsis thaliana. JOURNAL OF HAZARDOUS MATERIALS[J]. 2012, 199(1): 309-313, http://ir.ibcas.ac.cn/handle/2S10CLM1/16809.
[20] 麻密, 徐文忠, 腾瑶, 刘安娜. 一个编码含VQ模序蛋白的基因AtARVQ1参与拟南芥对砷酸盐的响应调控. 科学通报[J]. 2011, 56(23): 1891-1898, http://lib.cqvip.com/Qikan/Article/Detail?id=38846133.
[21] Ma, Wenwen, Xu, Wenzhong, Xu, Hua, Chen, Yanshan, He, Zhenyan, Ma, Mi. Nitric oxide modulates cadmium influx during cadmium-induced programmed cell death in tobacco BY-2 cells. PLANTA[J]. 2010, 232(2): 325-335, https://www.webofscience.com/wos/woscc/full-record/WOS:000278838500004.
[22] Teng, Yao, Xu, Wenzhong, Ma, Mi. cGMP is required for seed germination in Arabidopsis thaliana. JOURNAL OF PLANT PHYSIOLOGY[J]. 2010, 167(11): 885-889, http://dx.doi.org/10.1016/j.jplph.2010.01.015.
[23] Li, Beibei, Xu, Wenzhong, Xu, Yunyuan, Zhang, Yuanyuan, Wang, Tai, Bai, Yue, Han, Chenggui, Zhang, Aimin, Xu, Zhihong, Chong, Kang. Integrative Study on Proteomics, Molecular Physiology, and Genetics Reveals an Accumulation of Cyclophilin-Like Protein, TaCYP20-2, Leading to an Increase of Rht Protein and Dwarf in a Novel GA-Insensitive Mutant (gaid) in Wheat. JOURNAL OF PROTEOME RESEARCH[J]. 2010, 9(8): 4242-4253, http://www.corc.org.cn/handle/1471x/2407832.

科研活动

   
参与会议
(1)伴矿景天(Sedum plumbizincicola)超富集重金属镉的高抗性分子机制   第二届中国植物修复生物学学术研讨会   2019-05-31
(2)Molecular mechanism of Cd hypertolerance in hyperaccummulator Sedum plumbizincicola    2019-05-09
(3)Genetic engineering of plants for phytoremediation of co-contaminated soils with arsenic and cadmium   2018-07-01
(4)伴矿景天(Sedum plumbizincicola)超富集重金属镉的高抗性分子机制   第三届全国逆境生物学研讨会   2018-05-16
(5)镉砷复合污染修复工程植物研发   第7届农业环境科学研讨会   2017-10-25
(6)植物遗传改造治理镉砷复合污染土壤   第九届全国环境化学大会   2017-10-19
(7)Heavy metal ATPase 3 (HMA3) confers Cd-hypertolerant capacity for hyperaccummulator Sedum plumbizincicola   第十三届植物技术国际会议   2016-09-26
(8)Genetic modification to create engineering plants for phytoremediation of arsenic pollutions   第一届中日韩三边生物技术国际研讨会暨第五届全国植物生物技术及其产业化大会   2016-08-03
(9)应用基因改造技术研发重金属超富集工程植物   2016聚焦我国农业环境问题——农作物产地污染阻控技术专题研讨会   2016-05-13
(10)Development of novel assays for high through-put screening inhibitors of As(III) S-adenosyl-methionine methyltransferases   Wenzhong Xu, Hui Dong, Barry P. Rosen   2014-12-05