Dr. Yongbiao Xue, Principle Investigator, Ph.D. (1989, University of East Anglia and John Innes Centre, Norwich, Phone: 86-10-64801181Fax: 86-10-64801292Research Area : Plant Molecular and Reproductive Biology |
Research Areas
RESEARCH INTERESTS/AREAS
1. Molecular control of
self-incompatibility in Antirrhinum
Self-incompatibility (SI) is a widely-distributed genetic mechanism to prevent inbreeding in flowering plants and represents a model system to study molecular basis of pollen recognition and rejection. In solanaceous-type self-incompatible species, recent studies have shown that the S-locus encodes two types of genes in a haplotype manner controlling the pistil and pollen function of SI, respectively. A class of ribonucleases known as S-RNases mediates the pistil function, and a novel F-box gene called S-locus F-box (SLF) controls the pollen function. The first member of the SLF family, AhSLF-S2, was identified in Antirrhinum. We have shown that it mediates the pollen function of S-RNase-based SI and its protein product forms part of an SCF (Skp1/Cullin or CDC53/F-box) complex to target S-RNases for destruction by the ubiquitin/26S proteosome-mediated proteolytic pathway during compatible pollination. However, little is known about how these two proteins interact with each other to elicit SI responses. Currently, we are taking a combination of molecular genetics, biochemistry and cell biology to address this issue in Antirrhinum.
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2. Molecular studies on pollination and fertilization in rice
| Pollination and fertilization are key steps leading to seed formation. But, relatively little is known about their molecular control in rice. To identify genes involved in these processes, we have constructed a cDNA microarray containing over 10K unique cDNA in rice and monitored gene expression profiles during pollination. Subsequently, over 200 candidate cDNA have been found with possible roles in pollination in rice. We are investigating their detailed functions using a variety of approaches. In addition, we are collaborating with Drs Weiren Wu and Yuanling Duan from Fujian Agricultural University of China to clone several key genes controlling rice reproductive development using a map-based method. |
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3. Identification of genes controlling cotton fiber formation
Cotton fibers are single cell-derived structures from ovule epidermis. Very little is known about their molecular control. Based on the fact that both trichomes and fibers are derived from single cells, we have identified numerous MYB genes expressed during fiber formation. In particular, one gene known as GhMYB109 is specifically expressed in fiber initials and elongating fibers, suggesting that it likely controls these steps. Currently, we are disecting its function through a transgenic approach.
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RECENT MAJOR PUBICATIONS
(see http://plantbiol.genetics.ac.cn/the_xue_lab/publication01e.htm for a complete list)
Education
1983 BSc Lanzhou University,China
1986 Msc The Postgradute School, The Chinese Academy of Sciences, China
1989 PhD University of East Anglia, UK
ASSOCIATIONS AND FELLOWSHIPS
1987 University Studentship, University of East Anglia, UK
1987 Overseas Research Student Awards, University of East Anglia, UK
1995 K.C. Wang Fellowship, The Chinese Academy of Sciences, China
Experience
EMPLOYMENT HISTORY
1990 Postdoc Fellow, John Innes Center and University of Oxford (with Prof. E. S. Coen, FRS
and Prof. H. G. Dickinson), UK
1995 Research Scientist, The Sainsbury Laboratory, John Innes Center, UK
1997 Principle Investigator, Institute of Developmental Biology, The Chinese Academy of
Sciences, China
1999 Assistant Director, Institute of Developmental Biology, The Chinese Academy of
Sciences,China
2000 Professor, Faculty of Life Sciences, The Postgraduate School, The Chinese Academy of
Sciences, China
2001 Principle Investigator, Institute of Genetics and Developmental Biology, The Chinese
Academy of Sciences, China
2001 Associate Director, Institute of Genetics and Developmental Biology, The Chinese
Academy of Sciences, China
2002 Adjunct Professor, College of Life Sciences, Beijing University, China
2004-2014 Director,Institute of Genetics and Developmental Biology,The Chinese Academy of
Sciences,China
Work Experience
1990 Postdoc Fellow, John Innes Center and University of Oxford (with Prof. E. S. Coen, FRS
and Prof. H. G. Dickinson), UK
1995 Research Scientist, The Sainsbury Laboratory, John Innes Center, UK
1997 Principle Investigator, Institute of Developmental Biology, The Chinese Academy of
Sciences, China
1999 Assistant Director, Institute of Developmental Biology, The Chinese Academy of
Sciences,China
2000 Professor, Faculty of Life Sciences, The Postgraduate School, The Chinese Academy of
Sciences, China
2001 Principle Investigator, Institute of Genetics and Developmental Biology, The Chinese
Academy of Sciences, China
2001 Associate Director, Institute of Genetics and Developmental Biology, The Chinese
Academy of Sciences, China
2002 Adjunct Professor, College of Life Sciences, Beijing University, China
2004-2014 Director,Institute of Genetics and Developmental Biology,The Chinese Academy of
Sciences,China
Teaching Experience
2000- so far Techer of University of Chinese Academy Sciences.
Research Interests
Conferences
（2）Breaking down the reproductive barriers to interspecific hybridization in tomatoes 2015-06-29
（3）Breaking down the reproductive barriers tointerspecific hybridization in tomatoes 2014-11-08
（4）Breaking down the reproductive barriers tointerspecific crosses in tomatoes 2014-10-19
Students
已指导学生
陈伟 01 19181
索金凤 01 19181
郭艳霞 01 19181
黄剑 01 19181
乔红 01 19181
王飞 01 19181
蓝乐夫 01 19181
董丽 01 19181
赵岚 01 19181
周君莉 01 19181
孔照胜 01 19181
杨文强 01 19181
王蕾 01 19181
赖钊 01 19185
谈远钰 01 19181
王洪云 01 19181
杨秋颖 01 19181
来滢 01 19181
李美娜 01 19181
普莉 01 19181
邢卓 01 19182
张一婧 01 19182
周宇净 02 19182
范江波 01 19181
李钟惠 01 19181
赵仲华 01 19181
胡兴明 01 19181
隋镇华 01 19181
李峰 01 19181
徐驰 01 19182
郭晗 01 19181
陈光 01 19181
张彬 01 19181
张辉 01 19181
刘卫 01 19182
龚晓洁 01 19182
徐婷 01 19180
李俊慧 01 19180
张碧瑶 01 19181
现指导学生
宋砚斋 01 19180
李苗苗 01 19181
李想 02 19180
唐华山 01 19181
郭飞飞 01 19181
张越 01 19180
赵洪 01 19180
黄画秋 02 19180
房梓 01 19180
王鹏飞 01 19180
Paper
(2) A High Temperature-Dependent Mitochondrial Lipase EXTRA GLUME1 Promotes Floral Phenotypic Robustness against Temperature Fluctuation in Rice(Oryza sativa L.), PLOS Genetics., 2016, 通讯作者
(3) SCFSLF-mediated cytosolic degradation of S-RNase is required for cross-pollen compatibility in S-RNase-based self-incompatibility in Petuniahybrida, Front.Genet, 2014, 通讯作者
(4) Fine Mapping of the Maize Cross-Incompatibility Locus Gametophytic Factor 1 (ga1) Using a Homogeneous Population, Crop Science, 2014, 通讯作者
(5) Identification of a canonical SCFSLF complex involvedin S-RNase-based self-incompatibility of Pyrus (Rosaceae), Plant Mol. Biol., 2013, 通讯作者
(6) Genome-scale analysis and comparison of gene expression profiles in developing and germinated pollen in Oryza sativa. , BMC Genomics, 2010, 通讯作者
(7) The SKP1-like protein SSK1 is required for cross-pollen compatibility in S-RNase-based self-incompatibility. , Plant J, 2010, 通讯作者
(8) DEP and AFO regulate reproductive habit in rice., PLoS Genet, 2010, 通讯作者