1. Shaoquan Bian, …, Haobo Pan*, Xiaoli Zhao*. A shear-thinning adhesive hydrogel reinforced by photo-initiated crosslinking as a fit-to-shape tissue sealant. Journal of Materials Chemistry B, 2019, 7, 6488-6499 (IF ,5.047)
2. Qingchang Chen#, Jun Wu#, …, Xiaoli Zhao*, Haobo Pan. Electrospun chitosan/PVA/bioglass Nanofibrous membrane with spatially designed structure for accelerating chronic wound healing. Materials Science and Engineering: C,2019, 105, 110083. (IF 4.959)
3. Fei Gao, …, Xiaoli Zhao, Xu Cui, Changshun Ruan,* and Wenguang Liu*. Osteochondral Regeneration with 3D-Printed Biodegradable High-Strength Supramolecular Polymer Reinforced-Gelatin Hydrogel Scaffolds. Advanced Science, 2019, 1900867. (IF 15.804)
4. Liu Wenlong, …, Zhao Xiaoli, et al. Spatial Distribution of Biomaterial Microenvironment pH and Its Modulatory Effect on Osteoclasts at the Early Stage of Bone Defect Regeneration. ACS Appl. Mater. Interfaces,2019,11(9): 9557-9572 (IF8.456)
5. Qingchang Chen#, Chuping Zheng# , …, Xiaoli Zhao*, and William W. Lu. Bone Targeted Delivery of SDF‑1 via Alendronate Functionalized Nanoparticles in Guiding Stem Cell Migration. ACS Appl. Mater. Interfaces,2018, 10 (28), pp 23700–23710.
6. Chen qingchang, Liu Yuan, …, Zhao Xiaoli*. Chitosan-PVA monodisperse millimeter-sized spheres prepared by electrospraying reduce the thromboembolic risk in hemorrhage. Journal of Materials Chemistry B, 2017 ,5, 3686-3696 (IF8.456)
7. Xinyun Zhai, …, Xiaoli Zhao, Haobo Pan,* and William Weijia Lu. 3D-Bioprinted Osteoblast-Laden Nanocomposite Hydrogel Constructs with Induced Microenvironments Promote Cell Viability, Differentiation, and Osteogenesis both In Vitro and In Vivo, Advanced Science, 2018, 5(3): 1700550. （IF：15.804）
8. Zhao Y, …, Zhao XL, et al. Plasma Surface Functionalized Polyetheretherketone for Enhanced Osseo-Integration at Bone-Implant Interface. Acs Appl Mater Inter. 2016;8:3901-11.（IF：8.456）
9. Zheng CP, Pan HB, Zhao XL*. Alendronate-modified liposome for bone targeting gene delivery regulating mesenchymal stem cell migration. Journal of Orthopaedic Translation, 2016,7,128
10. Chen QC, Pan HB, Zhao XL*. Chitosan/PVA/Bioglass multilayer films for wound dressing application. Journal of Orthopaedic Translation, 2016,7,117-118
11. Li YQ, Pan HB, Zhao XL*. Promoting effect of strontium on the division of stem cells in bone formation. Journal of Orthopaedic Translation, 2016,7,129
12. Wenlong Liu, Ting Wang, Xiaoli Zhao, et al. Akermanite used as an alkaline biodegradable implants for the treatment of osteoporotic bone defect. Bioactive Materials, 2016,1,151-9
13. Wu Jun#, Zhao Xiaoli#, Yeung KW, To MK. Interfacial Fast Release Layer in Monodisperse Poly (lactic-co-glycolic acid) Microspheres Accelerates the Drug Release. Current Drug Delivery,2016,13(5):720-9
14. Wu S, Wu J, …, Zhao XL*, Poly(d,l-lacticacid) electrospun fibers with tunable surface nanotopography for modulating drug release profiles. Materials Letters,2015,161:716-19.
15. Wu S, Huang ZY, …, Zhao XL*. The efficient hemostatic effect of Antarctic krill chitosan is related toits hydration property. Carbohydrate Polymers, 2015,132:295-303. （IF：6.044）
16. Yue JH, Wu J, Liu D, Zhao XL*, Lu WW. BMP2 gene delivery to bone mesenchymal stem cell by chitosan-g-PEI nonviral vector. Nanoscale Research Letters,2015,10:203.
17. Wang L, Zhang L, …, Zhao X, Lu WW. Abnormal subchondral bone microstructure following steroid administration is involved in the early pathogenesis of steroid-induced osteonecrosis. Osteoporosis International, 2016;27:153-9.
18. Zhao XL，Li ZY, et al. Enhanced gene delivery by chitosan-disulfide-conjugated LMW-PEI for facilitating osteogenic differentiation. Acta Biomaterialia, 2013, 9(5):6694-6703.
19. Zhao XL, Li ZY, et al. Octaarginine-modified chitosan as a nonviral gene delivery vector: properties and in vitro transfection efficiency. J nanopart res, 2011,13:693-702.
20. Zhang JL, Wang N, Liu WG, Zhao XL, Lu William. Intermolecular hydrogen bonding strategy to fabricate mechanically strong hydrogels with high elasticity and fatigue resistance. Soft Matter, 2013,9:6331-6337. (IF:3.909)
21. Zhao XL, Yu B, et al. Nestin as marker for bone marrow mesenchymal stem cells. J Bone Miner Res, 2011, S2, 1006
22. Yu B, Zhao XL, Yang CZ, Crane J, Xian LL, Lu WW, Wan M, Cao X. Parathyroid Hormone Induces Differentiation of Mesenchymal Stromal/Stem Cells by Enhancing Bone Morphogenetic Protein Signaling. J Bone Miner Res, 2012,29,2001-2014.
23. Zhao XL, Liu WG, Chen DY, Lin XZ, Lu WW. Effect of block order of ABA- and BAB-type NIPAAm/HEMA triblock copolymers on thermoresponsive behavior of solutions. Macromol Chem Phys, 2007, 208,1773-1781.
24. Pan HB, Zhao XL, Darvell WB, Lu WW. Apatite-formation ability – predictor of “bioactivity”? Acta Biomaterialia, 2010,6， 4181-4188.
25. Pan HB, Zhao XL, et al. Strontium borate glass: potential biomaterial for bone regeneration. J R Soc Interface, 2010, 7,1025-1031.(IF:4.097)
26. Bai T, Zhang P, …, Zhao XL, Lu WW. Construction of an ultrahigh strength hydrogel with excellent fatigue resistance based on strong dipole-dipole interaction. Soft Matter, 2011,7(6):2825-2831.
27. Dai FY, Tang L, Yang JH, Zhao XL, et al. Fast thermoresponsive BAB-type HEMA/NIPAAm triblock copolymer solutions for embolization of abnormal blood vessels. J Mater Sci Mater Med, 2009, 20, 967-974.
28. Cao ZQ, Liu WG, Ye GX, Zhao XL, Lin XZ, Gao P, Yao KD. N-isopropylacrylamide/2-Hydroxyethyl Methacrylate Star Diblock Copolymers: Synthesis and Thermo-responsive Behavior. Macromol Chem Phys, 2006, 207, 2329-2335.
29. Tian F, Zhang BQ, Zhao XL*, Ji WH, Li XW, Cheng GX, Yao KD. In vitro evaluation of embolization effects of thermosensitive N-isopropylacrylamide based copolymer solutions. Polymer International, 2006, 55, 405-408.
发表论文
[1] Zhiyang Zhang, Rui Su, Fei Han, Zhiqiang Zheng, Yuan Liu, Xiaomeng Zhou, Qingsong Li, Xinyun Zhai, Jun Wu, Xiaohua Pan, Haobo Pan, Peizhi Guo, Zhaoyang Li, Zhiyuan Liu, Xiaoli Zhao. A soft intelligent dressing with pH and temperature sensors for early detection of wound infection †. RSC Advances[J]. 2022, 12(6): 3243-3252, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8979260/.[2] Jun Wu, Feihong Liu, Zejin Wang, Yuan Liu, Xiaoli Zhao, Christian Fang, Frankie Leung, Kelvin W K Yeung, Tak Man Wong. The Development of a Magnesium-Releasing and Long-Term Mechanically Stable Calcium Phosphate Bone Cement Possessing Osteogenic and Immunomodulation Effects for Promoting Bone Fracture Regeneration. Frontiers in Bioengineering and Biotechnology[J]. 2022, 9: https://doaj.org/article/4989b7377f734e269ccb4be3b197b4fd.[3] Li, Feiyang, Wu, Jun, Li, Daiye, Hao, Liuzhi, Li, Yanqun, Yi, Dan, Yeung, Kelvin W K, Chen, Di, Lu, William W, Pan, Haobo, Wong, Tak Man, Zhao, Xiaoli. Engineering stem cells to produce exosomes with enhanced bone regeneration effects: an alternative strategy for gene therapy. JOURNAL OF NANOBIOTECHNOLOGY[J]. 2022, 20(1): http://dx.doi.org/10.1186/s12951-022-01347-3.[4] He, Xi, Zhou, Meiling, Chen, Xuemei, Wang, Jing, Zhao, Xiaoli, Zhu, Yanxia, Liu, Tao. Development and Characterization of Multifunctional Wound Dressing with the Property of Anti-bacteria and Angiogenesis. PROBIOTICS AND ANTIMICROBIAL PROTEINS. 2022, [5] Huang, Yongkang, Zhai, Xinyun, Ma, Tengfei, Zhang, Mengzhen, Pan, Haobo, Lu, William Weijia, Zhao, Xiaoli, Sun, Tianwei, Li, Yuqiao, Shen, Jie, Yan, Chunhua, Du, Yaping. Rare earth-based materials for bone regeneration: Breakthroughs and advantages. COORDINATION CHEMISTRY REVIEWSnull. 2022, 450: http://dx.doi.org/10.1016/j.ccr.2021.214236.[6] Ma, Tengfei, Zhai, Xinyun, Huang, Yongkang, Zhang, Mengzhen, Zhao, Xiaoli, Du, Yaping, Yan, Chunhua. A Smart Nanoplatform with Photothermal Antibacterial Capability and Antioxidant Activity for Chronic Wound Healing. ADVANCED HEALTHCARE MATERIALS[J]. 2021, 10(13): http://dx.doi.org/10.1002/adhm.202100033.[7] Li, Yanqun, Yue, Jianhui, Liu, Yuan, Wu, Jun, Guan, Min, Chen, Di, Pan, Haobo, Zhao, Xiaoli, Lu, William W. Strontium regulates stem cell fate during osteogenic differentiation through asymmetric cell division. ACTA BIOMATERIALIA[J]. 2021, 119: 432-443, http://dx.doi.org/10.1016/j.actbio.2020.10.030.[8] Yi, Dan, Yu, Huan, Lu, Ke, Ruan, Changshun, Ding, Changhai, Tong, Liping, Zhao, Xiaoli, Chen, Di. AMPK Signaling in Energy Control, Cartilage Biology, and Osteoarthritis. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGYnull. 2021, 9: http://dx.doi.org/10.3389/fcell.2021.696602.[9] Zhai, Xinyun, Ruan, Changshun, Shen, Jie, Zheng, Chuping, Zhao, Xiaoli, Pan, Haobo, Lu, William Weijia. Clay-based nanocomposite hydrogel with attractive mechanical properties and sustained bioactive ion release for bone defect repair. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2021, 9(10): 2394-2406, http://dx.doi.org/10.1039/d1tb00184a.[10] Pang, Libin, Tian, Pengfei, Cui, Xu, Wu, Xiuping, Zhao, Xiaoli, Wang, Hui, Wang, Deping, Pan, Haobo. In Situ Photo-Cross-Linking Hydrogel Accelerates Diabetic Wound Healing through Restored Hypoxia-Inducible Factor 1-Alpha Pathway and Regulated Inflammation. ACS APPLIED MATERIALS & INTERFACES[J]. 2021, 13(25): 29363-29379, http://dx.doi.org/10.1021/acsami.1c07103.[11] Wang, Jing, Xiong, Hao, Zhu, Tonghe, Liu, Yuan, Pan, Haobo, Fan, Cunyi, Zhao, Xiaoli, Lu, William Weijia. Bioinspired Multichannel Nerve Guidance Conduit Based on Shape Memory Nanofibers for Potential Application in Peripheral Nerve Repair. ACS NANO[J]. 2020, 14(10): 12579-12595, https://www.webofscience.com/wos/woscc/full-record/WOS:000586793400017.[12] Feiyang Li, Yuan Liu, Yingqi Xu, Yanqun Li, Juan Liu, Minmin Lv, Changshun Ruan, Haobo Pan, Xiaoli Zhao. Ratiometric Fluorescent Microgels for Sensing Extracellular Microenvironment pH during Biomaterial Degradation. ACS OMEGA[J]. 2020, 5(31): 19796-19804, https://www.webofscience.com/wos/woscc/full-record/WOS:000562138900051.[13] Zhiqiang Zheng, Shaoquan Bian, Zhiqiang Li, Zhiyang Zhang, Yuan Liu, Xinyun Zhai, Haobo Pan, Xiaoli Zhao. Catechol modified quaternized chitosan enhanced wet adhesive and antibacterial properties of injectable thermo-sensitive hydrogel for wound healing. Carbohydrate Polymers. 2020, 249: [14] Qingchang Chen, Jun Wu, Yuan Liu, Yanqun Li, Chuqiu Zhang, Weichen Qi, Kelvin WK Yeung, Tak Man Wong, Xiaoli Zhao, Haobo Pan. Electrospun chitosan/PVA/bioglass Nanofibrous membrane with spatially designed structure for accelerating chronic wound healing. Materials Science & Engineering C. 2019, 105: http://dx.doi.org/10.1016/j.msec.2019.110083.[15] Gao, Fei, Xu, Ziyang, Liang, Qingfei, Li, Haofei, Peng, Liuqi, Wu, Mingming, Zhao, Xiaoli, Cui, Xu, Ruan, Changshun, Liu, Wenguang. Osteochondral Regeneration with 3D-Printed Biodegradable High-Strength Supramolecular Polymer Reinforced-Gelatin Hydrogel Scaffolds. ADVANCED SCIENCE[J]. 2019, 6(15): https://doaj.org/article/7a8457ed56f346eaa5c7c99fe39f48ca.[16] Bian, Shaoquan, Zheng, Zhiqiang, Liu, Yuan, Ruan, Changshun, Pan, Haobo, Zhao, Xiaoli. A shear-thinning adhesive hydrogel reinforced by photo-initiated crosslinking as a fit-to-shape tissue sealant. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2019, 7(42): 6488-6499, http://dx.doi.org/10.1039/c9tb01521c.[17] Liu, Wenlong, Dan, Xiuli, Lu, William W, Zhao, Xiaoli, Ruan, Changshun, Wang, Ting, Cui, Xu, Zhai, Xinyun, Ma, Yufei, Wang, Deping, Huang, Wenhai, Pan, Haobo. Spatial Distribution of Biomaterial Microenvironment pH and Its Modulatory Effect on Osteoclasts at the Early Stage of Bone Defect Regeneration. ACS APPLIED MATERIALS & INTERFACES[J]. 2019, 11(9): 9557-9572, [18] Zhai, Xinyun, Ruan, Changshun, Ma, Yufei, Cheng, Delin, Wu, Mingming, Liu, Wenguang, Zhao, Xiaoli, Pan, Haobo, Lu, William Weijia. 3D-Bioprinted Osteoblast-Laden Nanocomposite Hydrogel Constructs with Induced Microenvironments Promote Cell Viability, Differentiation, and Osteogenesis both In Vitro and In Vivo. ADVANCED SCIENCE[J]. 2018, 5(3): https://doaj.org/article/efa4b2d7a29043db84a74a694073c8e7.[19] Chen, Qingchang, Zheng, Chuping, Li, Yanqun, Bian, Shaoquan, Pan, Haobo, Zhao, Xiaoli, Lu, William W. Bone Targeted Delivery of SDF-1 via Alendronate Functionalized Nanoparticles in Guiding Stem Cell Migration. ACS APPLIED MATERIALS & INTERFACES[J]. 2018, 10(28): 23700-23710, http://ir.siat.ac.cn:8080/handle/172644/14727.[20] 刘缘, 潘浩波, 赵晓丽. 南极磷虾壳聚糖的提取及止血研究. 集成技术. 2018, 43-50, http://lib.cqvip.com/Qikan/Article/Detail?id=WD74677488504849564849484853.[21] Xiaoli Zhao. 3D-Bioprinted Osteoblast-Laden Nanocomposite Hydrogel. Constructs with Induced Microenvironments Promote Cell Viability, Differentiation, and Osteogenesis both In Vitro and In Vivo.. Advanced Science. 2017, [22] Xiaoli Zhao. Chitosan-PVA monodisperse millimeter-sized spheres 1 prepared by electrospraying reduce the thromboembolic risk in hemorrhage. Journal of Materials Chemistry B. 2017, [23] Qingchang Chen, Haobo Pan, Xiaoli Zhao. Chitosan/PVA/Bioglass multilayer films for wound dressing application. Journal of Orthopaedic Translation[J]. 2016, 7(C): 117-118, http://dx.doi.org/10.1016/j.jot.2016.06.140.[24] Chuping Zheng, Haobo Pan, Xiaoli Zhao. Alendronate-modified liposome for bone targeting gene delivery regulating mesenchymal stem cell migration. Journal of Orthopaedic Translation[J]. 2016, 7(C): 128-128, http://dx.doi.org/10.1016/j.jot.2016.06.171.[25] Wu, Jun, Zhao, Xiaoli, Yeung, Kelvin W K, To, Michael K T. Interfacial Fast Release Layer in Monodisperse Poly (lactic-co-glycolic acid) Microspheres Accelerates the Drug Release. CURRENT DRUG DELIVERY[J]. 2016, 13(5): 720-729, https://www.webofscience.com/wos/woscc/full-record/WOS:000384800000009.[26] Wenlong Liu, Ting Wang, Xiaoli Zhao, Xiuli Dan, William W Lu, Haobo Pan. Akermanite used as an alkaline biodegradable implants for the treatment of osteoporotic bone defect. Bioactive Materials[J]. 2016, 1(2): 151-159, http://lib.cqvip.com/Qikan/Article/Detail?id=7103845419.[27] Wang, L, Zhang, L, Pan, H, Peng, S, Zhao, X, Lu, W W. Abnormal subchondral bone microstructure following steroid administration is involved in the early pathogenesis of steroid-induced osteonecrosis. OSTEOPOROSIS INTERNATIONAL[J]. 2016, 27(1): 153-159, https://www.webofscience.com/wos/woscc/full-record/WOS:000369525500018.[28] Zhao, Ying, Wong, Hoi Man, Lui, So Ching, Chong, Eva Y W, Wu, Guosong, Zhao, Xiaoli, Wang, Chong, Pan, Haobo, Cheung, Kenneth M C, Wu, Shuilin, Chu, Paul K, Yeung, Kelvin W K. Plasma Surface Functionalized Polyetheretherketone for Enhanced Osseo-Integration at Bone-Implant Interface. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 8(6): 3901-3911, https://www.webofscience.com/wos/woscc/full-record/WOS:000370583100042.[29] Wu, Shuai, Wu, Jun, Yue, Jianhui, To, Michael K T, Pan, Haobo, Lu, William W, Zhao, Xiaoli. Poly (d,l-lactic acid) electrospun fibers with tunable surface nanotopography for modulating drug release profiles. MATERIALS LETTERS[J]. 2015, 161: 716-719, http://dx.doi.org/10.1016/j.matlet.2015.09.065.[30] Yue, Jianhui, Wu, Jun, Liu, Di, Zhao, Xiaoli, Lu, William W. BMP2 gene delivery to bone mesenchymal stem cell by chitosan-g-PEI nonviral vector. 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ACTA BIOMATERIALIA[J]. 2013, 9(5): 6694-6703, http://dx.doi.org/10.1016/j.actbio.2013.01.039.[34] Bing Yu, Xiaoli Zhao, Chaozhe Yang, Janet Crane, Lingling Xian, William Lu, Mei Wan, Xu Cao. PTH Induces Differentiation of Mesenchymal Stem Cells by Enhancing BMP Signaling. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2012, 27(9): 2001-2014, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423493/.[35] Zhao, Xiaoli, Li, Zhaoyang, Liu, Wenguang, Lam, Wingmoon, Sun, Peng, Kao, Richard Y T, Luk, Keith D K, Lu, William W. Octaarginine-modified chitosan as a nonviral gene delivery vector: properties and in vitro transfection efficiency. JOURNAL OF NANOPARTICLE RESEARCH[J]. 2011, 13(2): 693-702, https://www.webofscience.com/wos/woscc/full-record/WOS:000287860200024.[36] Pan, Haobo, Zhao, Xiaoli, Darvell, Brian W, Lu, William W. Apatite-formation ability - Predictor of "bioactivity"?. ACTA BIOMATERIALIAnull. 2010, 6(11): 4181-4188, http://dx.doi.org/10.1016/j.actbio.2010.05.013.[37] Pan, H B, Zhao, X L, Zhang, X, Zhang, K B, Li, L C, Li, Z Y, Lam, W M, Lu, W W, Wang, D P, Huang, W H, Lin, K L, Chang, J. Strontium borate glass: potential biomaterial for bone regeneration. JOURNAL OF THE ROYAL SOCIETY INTERFACE[J]. 2010, 7(48): 1025-1031, https://www.webofscience.com/wos/woscc/full-record/WOS:000277991600002.[38] Dai, Fengying, Tang, Lei, Yang, Jianhai, Zhao, Xiaoli, Liu, Wenguang, Chen, Guang, Xiao, Fushun, Feng, Xuequan. Fast thermoresponsive BAB-type HEMA/NIPAAm triblock copolymer solutions for embolization of abnormal blood vessels. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE[J]. 2009, 20(4): 967-974, https://www.webofscience.com/wos/woscc/full-record/WOS:000263683900016.[39] Zhao, Xiaoli, Liu, Wenguang, Chen, Dayong, Lin, Xiaoze, Lu, William W. Effect of block order of ABA- and BAB-type NIPAAm/HEMA triblock copolymers on thermoresponsive Behavior of solutions. MACROMOLECULAR CHEMISTRY AND PHYSICS[J]. 2007, 208(16): 1773-1781, https://www.webofscience.com/wos/woscc/full-record/WOS:000249050000007.[40] Tian, F, Zhang, BQ, Zhao, XL, Ji, WH, Li, XW, Cheng, GX, Yao, KD. In vitro evaluation of embolization effects of thermosensitive N-isopropylacrylamide-based copolymer solutions. POLYMER INTERNATIONAL[J]. 2006, 55(4): 405-408, https://www.webofscience.com/wos/woscc/full-record/WOS:000236473200005.[41] Cao, Zhiqiang, Liu, Wenguang, Ye, Guixiang, Zhao, Xiaoli, Lin, Xiaoze, Gao, Peng, Yao, Kangde. N-isopropylacrylamide/2-hydroxyethyl methacrylate star diblock copolymers: Synthesis and thermoresponsive behavior. MACROMOLECULAR CHEMISTRY AND PHYSICS[J]. 2006, 207(24): 2329-2335, https://www.webofscience.com/wos/woscc/full-record/WOS:000243389200007.[42] []. Interfacial Fast Release Layer in Monodisperse Poly (lactic-co-glycolic acid) Microspheres Accelerates the Drug Release.. http://ir.siat.ac.cn:8080/handle/172644/10776.
