Molecular epidemiology of avian influenza virus；

The interaction ​between influenza virus and host.

2003-09--2007-07   Wuhan Institute of Virology, CAS  PHD

2000-09--2003-07   Huazhong Agricultural of University    Master

1993-09--1997-07   Huazhong Agricultural of University      Bachelor

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2017.09-2018.08, French National Institute of Health and Medical（Inserm）

2009.09-2017.08, Associate Professor at Wuhan Institute of Virology, CAS.

2007.07-2009.08, Assistant Professor at Wuhan Institute of Virology, CAS.

2014-2016, Wuhan Institute of Virology, teaching the emerging infectious diseases and biosafety  training;

2015.05.30-07.02, INSERM Jean Mérieux BSL4 Laboratory, In vitro experimentation and training for virus infection.

   

1.        Two reassortant types of highly pathogenic H5N8 avian influenza virus from wild birds in Central China in 2016. Emerg Microbes Infect. 2018, Correspondence author

2.        Linear DNA vaccine prepared by large-scale PCR provides protective immunity against H1N1 influenza virus infection in mice. Vet Microbiol. 2017, Co-author

3.        Genesis, Evolution and Prevalence of H5N6 Avian Influenza Viruses in China. Cell Host & Microbe. 2016, Co-author

4.        First documented case of avian influenza (H5N1) virus infection in a lion.

            Emerg Microbes Infect. 2016, First author

6.        Novel avian influenza A (H5N6) viruses isolated in migratory waterfowl before the first human case reported in China,

       2014., Sci Rep., 2016, Correspondence author

7.        Comparison of concentration methods for detection of hepatitis A virus in water samples., Virol Sin., 2016, Correspondence

        author

8.        Deep sequencing reveals the viral adaptation process of environment-derived H10N8 in mice., Infect Genet

        Evol., 2016, Correspondence author

9.        Changes in the Length of the Neuraminidase Stalk Region Impact H7N9 Virulence in Mice., J Virol., 2015, First author

10.    Two novel reassortants of avian influenza A (H5N6) virus in China., J Gen Virol, 2015, Correspondence author

11.    Fusion-related host proteins are actively regulated by NA during influenza infection as revealed by quantitative proteomics

       analysis., PLoS One, 2014, Correspondence author

12.    Genotype diversity of H9N2 viruses isolated from wild birds and chickens in Hunan Province, China., PLoS

       One, 2014, Correspondence author

13.    NA proteins of influenza A viruses H1N1/2009, H5N1, and H9N2 show differential effects on infection initiation, virus

       release, and cell-cell fusion., PLoS One, 2013, First author

14.    A second CRM1-dependent nuclear export signal in the influenza A virus NS2 protein contributes to the nuclear export of

       viral ribonucleoproteins., J Virol, 2013, Third author

(1) A method of enriching hepatitis A virus in water body based on mixed cellulose ester film, invention, 2015, First author, patent number: 201410037633.X

(1)Molecular epidemiology of avian influenza virus；

(2)The interaction between influenza virus and host.

   

(1) Enrichment and purification technology of hepatitis A virus in water. National Science and Technology Support Program, Participation, national,2013.01-2016.12;

(2) Influenza research and early warning center, Chinese Academy of Sciences, Participation, ministries,2015.03-2016.12;

(3) Anti-H9N2&H5N1 subtype avian influenza virus  effect of an antibacterial peptide, PI, Institute (school), 2013.06—2016.12;

(4) The biological function of H7N9 virus with NA stem deletion, Participation, Institute (school), 2015.01-2016.12.

(1)  Ninety-fifth stage Shuangqing forum "Frontier Scientific Issues of Influenza Virus" sponsored by department of medical science, National Natural Science Foundation of China. Invited presentations , Quanjiao Chen, 28-29 May, 2013.

(2) Non-continuous and continuous transmission of influenza virus: migratory birds and poultry, China-Russia International Symposium on Influenza, Invited presentations, Quanjiao Chen, 2014-05-08.

已指导学生

郑华斌  博士研究生  071005-微生物学  

桂锐  博士研究生  071010-生物化学与分子生物学  

周豪  硕士研究生  085238-生物工程  

现指导学生

马莉萍  博士研究生  100103-病原生物学  

姚中子  博士研究生  100103-病原生物学  

熊加松  博士研究生  100103-病原生物学  

唐洋宇  硕士研究生  086000-生物与医药  

叶昶  博士研究生  100103-病原生物学  

刘仁怡  博士研究生  100103-病原生物学  

(1) Institute of Microbiology, Chinese Academy of Sciences (2) National institute of Metrology,China (3) Beijing Normal University (4) China National Genebank-Shenzhen, BGI-Shenzhen, Shenzhen

(1) Hubei University (2) Hunan Normal University (3) Jiangxi Agricultural University

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