Metabolic engineering, Synthetic biology, Microbial cell factory, Methanol transformation

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Joint Ph.D, University of Pittsburgh, 2015/10 - 2016.10

Ph.D. in Biochemical Engineering, Dalian University of Technology, 2012/09 - 2017/10

Bachelor in Biological Engineering, Dalian University of Technology, 2008/09 - 2012/07

   

Associate Professor, Dalian Institute of Chemical Physics, CAS, 2022/06 - Present

Assistant Professor, Dalian Institute of Chemical Physics, CAS, 2017/10 - 2022.06

   

1. Gao J.Q., Li Y.X., Yu W., Zhou Y.J.*, Rescuing yeast from cell death enables overproduction of fatty acids from sole methanol, Nature Metabolism, 2022, 4, 932-943.

2. Gao N.#, Gao J.Q.#, Yu W., Kong S.J., Zhou Y.J.*, Spatial-temporal regulation of fatty alcohol biosynthesis in yeast, Biotechnology for Biofuels Bioproducts, 2022, 15, 141.

3. Gao J.Q., Gao N., Zhai X.X., Zhou Y.J.*, Recombination machinery engineering for precise genome editing in methylotrophic yeast Ogataea polymorpha, iScience, 2021, 24(3), 102168.

4. Chen R.B., Gao J.Q., Yu W., Chen X.H., Zhai X.X., Chen Y., Zhang L.*, Zhou Y.J.*, Engineering cofactor supply and recycling to drive phenolic acid biosynthesis in yeast, Nature Chemical Biology, 2022, 18, 520-529.

5. Li Y.X., Zhai X.X., Yu W., Feng D., Shah A.A., Gao J.Q.*, Zhou Y.J.*, Production of free fatty acids from various carbon sources by Ogataea polymorpha, Bioresour. Bioprocess., 2022, 9, 78.

6. Yan C.X., Yu W., Yao L., Guo X.Y., Zhou Y.J., Gao J.Q.*, Expanding the promoter toolbox for metabolic engineering of methylotrophic yeasts，Appl. Microbiol. Biotechnol., 2022, 106(9-10), 3449-3464.

7. Yan C.X., Yu W., Zhai X.X., Yao L., Guo X.Y.*, Gao J.Q.*, Zhou Y.J., Characterizing and engineering promoters for metabolic engineering of Ogataea polymorpha, Synth. Syst. Biotechnol., 2022, 7, 498-505.

8. Gao J.Q., Zhou Y.J.*, Repurposing peroxisomes for microbial synthesis for biomolecules, Methods Enzymol., 2019, 617, 83-111.

​1. Construction of superior yeast cell factories for efficient production of chemicals.

2. Development of synthetic biology tools in non-conventional yeasts.

3. Revealing mechanisms on methanol toxicity during bio-productions.