基本信息
李广乐  男  博导  中国科学院过程工程研究所
电子邮件: liguangle@ipe.ac.cn
通信地址: 北京市海淀区中关村北二街1号
邮政编码:

招生信息

   
招生专业
080502-材料学
招生方向
液-液相分离,自组装

教育背景

2013-09--2018-06   中国科学院化学研究所   博士研究生
2009-09--2013-06   山东大学   本科

工作经历

   
工作简历
2018-11~2023-12,University of Hawaii at Manoa, 博士后

出版信息

   
发表论文
(1) Peptide-mediated liquid–liquid phase separation and biomolecular condensates, Soft Matter, 2025, 第 1 作者
(2) Biophysical mechanisms of SARS-CoV-2-induced surfactant inhibition, Biophysical Journal, 2025, 第 1 作者
(3) Entropy-Driven Amino Acid-Based Coacervates with Enzyme-Free Metabolism and Prebiotic Robustness, Journal of the American Chemical Society, 2025, 第 1 作者
(4) Investigating the influence of particle hydrophobicity on lung deposition using nonionic dye partitioning, Nano Today, 2024, 第 1 作者
(5) Constrained drop surfactometry for studying adsorbed pulmonary surfactant at physiologically relevant high concentrations, American Journal of Physiology-Lung Cellular and Molecular Physiology, 2023, 第 2 作者
(6) Biophysical function of pulmonary surfactant in liquid ventilation, Biophysical Journal, 2023, 第 1 作者
(7) Comparative biophysical study of meibomian lipids of wild type and Soat1-null mice: implications to meibomian gland dysfunction and dry eye disease, Investigative Ophthalmology & Visual Science, 2023, 第 3 作者
(8) Airborne fine particles drive H1N1 viruses deep into the lower respiratory tract and distant organs, Science Advances, 2023, 第 7 作者
(9) Phase transitions of the pulmonary surfactant film at the perfluorocarbon-water interface, Biophysical Journal, 2023, 第 1 作者
(10) Langmuir-Blodgett transfer from the oil-water interface, Journal of Colloid and Interface Science, 2023, 第 1 作者
(11) Effect of model tear film lipid layer on water evaporation, Investigative Ophthalmology & Visual Science, 2023, 第 2 作者
(12) Microplastics and nanoplastics impair the biophysical function of pulmonary surfactant by forming heteroaggregates at the alveolar–capillary interface, Environmental Science & Technology, 2023, 第 5 作者
(13) Adverse biophysical impact of e-cigarette flavors on pulmonary surfactant, Environmental Science & Technology, 2023, 第 3 作者
(14) Self-assembled aluminum oxyhydroxide nanorices with superior suspension stability for vaccine adjuvant, Journal of Colloid and Interface Science, 2022, 第 4 作者
(15) S2 subunit of SARS-CoV-2 spike protein induces domain fusion in natural pulmonary surfactant monolayers, The Journal of Physical Chemistry Letters, 2022, 第 1 作者
(16) Menthol in electronic cigarettes causes biophysical inhibition of pulmonary surfactant, American Journal of Physiology-Lung Cellular and Molecular Physiology, 2022, 第 5 作者
(17) Biophysical properties of tear film lipid layer I. Surface tension and surface rheology, Biophysical Journal, 2022, 第 2 作者
(18) Molecular and colloidal self-assembly at the oil–water interface, Current Opinion in Colloid & Interface Science, 2022, 第 1 作者
(19) Quantitative determination of the hydrophobicity of nanoparticles, Analytical Chemistry, 2022, 第 1 作者
(20) Boric Acid‐Fueled ATP Synthesis by FoF1 ATP Synthase Reconstituted in a Supramolecular Architecture, Angewandte Chemie International Edition, 2021, 第 4 作者
(21) Relative dye adsorption method for determining the hydrophobicity of nanoparticles, The Journal of Physical Chemistry C, 2021, 第 1 作者
(22) Compound drop shape analysis with the Neumann number, Langmuir, 2020, 第 1 作者
(23) Nanozyme‐catalyzed cascade reactions for mitochondria‐mimicking oxidative phosphorylation, Angewandte Chemie International Edition, 2019, 第 3 作者
(24) Proton-consumed nanoarchitectures toward sustainable and efficient photophosphorylation, Journal of Colloid and Interface Science, 2019, 第 1 作者
(25) Tuning Thiol‐Based Self‐Assembled Monolayer Chemistry on a Gold Surface towards the Synthesis of Biochemical Fuel, Angewandte Chemie International Edition, 2019, 第 1 作者
(26) Co-assembly of thylakoid and graphene oxide as a photoelectrochemical composite film for enhanced mediated electron transfer, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2018, 第 2 作者
(27) Optically matched semiconductor quantum dots improve photophosphorylation performed by chloroplasts, Angewandte Chemie International Edition, 2018, 第 3 作者
(28) Directed self-assembly of dipeptide single crystal in a capillary, ACS Nano, 2018, 第 6 作者
(29) Supramolecular assembly of photosystem II and adenosine triphosphate synthase in artificially designed honeycomb multilayers for photophosphorylation, ACS Nano, 2018, 第 3 作者
(30) Fabrication of one-dimensional gold hierarchical nanostructures through supramolecular assembly, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2018, 第 5 作者
(31) A photoinduced reversible phase transition in a dipeptide supramolecular assembly, Angewandte Chemie International Edition, 2018, 第 6 作者
(32) Bioinspired Assembly of Hierarchical Light‐Harvesting Architectures for Improved Photophosphorylation, Advanced Functional Materials, 2018, 第 1 作者
(33) Compartmentalized assembly of motor protein reconstituted on protocell membrane toward highly efficient photophosphorylation, ACS Nano, 2017, 第 3 作者
(34) Enhanced photophosphorylation of a chloroplast‐entrapping long‐lived photoacid, Angewandte Chemie International Edition, 2017, 第 3 作者
(35) Interfacial Assembly of Photosystem II with Conducting Polymer Films toward Enhanced Photo‐Bioelectrochemical Cells, Advanced Materials Interfaces, 2017, 第 1 作者
(36) Co-assembly of photosystem II/reduced graphene oxide multilayered biohybrid films for enhanced photocurrent, Nanoscale, 2015, 第 4 作者
发表著作
(1) Nano-bio Interactions in the Lung, Springer Singapore, 2023-01, 第 1 作者
(2) Photosystem II Based Multilayers, Springer Singapore, 2017-10, 第 2 作者

科研活动

   
科研项目
( 1 ) 基于液-液相分离的肽基凝聚体在生物大分子药物高效递送中的应用, 负责人, 研究所自主部署, 2025-01--2027-12
( 2 ) 液-液相分离凝聚体液滴的界面张力测量及其物化基础研究, 负责人, 国家任务, 2025-01--2027-12
( 3 ) 过程杰青, 负责人, 中国科学院计划, 2024-03--2028-12
参与会议
(1)肺表面活性剂/外源物质界面相互作用及生物医学应用   中国化学会第19届胶体与界面化学学术会议   2025-11-02
(2)Droplet-Based Langmuir-Blodgett Film Balance for Studying Self- Assembled Monolayers at the Oil-Water Interface   2022-07-10
(3)Characterizing the Hydrophobicity of Nanoparticles: From Qualitative to Quantitative Methods   2022-07-10
(4)Biophysical Function of Pulmonary Surfactant in Liquid Ventilation   2022-07-10
(5)Biophysical Function of Pulmonary Surfactant in Liquid Ventilation   2022-04-07
(6)Quantitative Characterization of the Hydrophobicity of Nanoparticles   2022-04-04
(7)Analyzing the Shape of Compound Droplets Using an Alternative Bond Number   2021-12-16
(8)Quantitatively Characterizing the Hydrophobicity of Nanoparticles   2021-12-16
(9)Axisymmetric Drop Shape Analysis of Compound Droplets   2021-06-14
(10)An Easy-to-use Method for Quantitatively Determining the Hydrophobicity of Nanoparticles   2021-06-14