100704-药物分析学

生物质谱技术开发和应用

2014-08--2024-05   美国圣路易华盛顿大学   博士学位
2005-09--2009-06   西北民族大学   本科学士学位

   

2021-04~2024-05,美国BioMarin制药公司, 研发科学家
2019-11~2021-04,美国斯克里普斯研究所, 博士后
2014-08~2024-05,美国圣路易华盛顿大学, 博士学位
2009-07~2024-07,中国科学院上海药物研究所, 研究实习员
2005-09~2009-06,西北民族大学, 本科学士学位

   

（1） Workflow for Validating Specific Amino Acid Footprinting Reagents for Protein Higher Order Structure Elucidation, ANALYTICAL CHEMISTRY, 2023, 第 4 作者
（2） Precursor Reagent Hydrophobicity Affects Membrane Protein Footprinting, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2023, 第 2 作者
（3） Benzoyl Transfer for Footprinting Alcohol-Containing Residues in Higher Order Structural Applications of Mass-Spectrometry-Based Proteomics, ANALYTICAL CHEMISTRY, 2022, 第 2 作者
（4） Bioanalysis of Oligonucleotide by LC-MS: Effects of Ion Pairing Regents and Recent Advances in Ion-Pairing-Free Analytical Strategies, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 第 2 作者
（5） Diethylpyrocarbonate Footprints a Membrane Protein in Micelles, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2021, 第 2 作者
（6） Free-Radical Membrane Protein Footprinting by Photolysis of Perfluoroisopropyl Iodide Partitioned to Detergent Micelle by Sonication, ANGEWANDTE CHEMIE (INTERNATIONAL ED. IN ENGLISH), 2021, 第 1 作者
（7） Structure of cyanobacterial phycobilisome core revealed by structural modeling and chemical cross-linking, SCIENCE ADVANCES, 2021, 第 4 作者
（8） Site-Specific Siderocalin Binding to Ferric and Ferric-Free Enterobactin As Revealed by Mass Spectrometry, ACS CHEMICAL BIOLOGY, 2020, 第 3 作者
（9） The Application of Fluorine-Containing Reagents in Structural Proteomics, ANGEWANDTE CHEMIE (INTERNATIONAL ED. IN ENGLISH), 2020, 第 1 作者
（10） Fast Protein Footprinting by X-ray Mediated Radical Trifluoromethylation, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2020, 第 1 作者
（11） Phycobilisomes Harbor FNR L in Cyanobacteria, MBIO, 2019, 第 4 作者
（12） Cryo-EM structure of Chikungunya virus in complex with the Mxra8 receptor, CELL, 2019, 第 8 作者
（13） Protein-Metal-Ion Interactions Studied by Mass Spectrometry-Based Footprinting with Isotope-Encoded Benzhydrazide, ANALYTICAL CHEMISTRY, 2019, 第 2 作者
（14） Implementing fast photochemical oxidation of proteins (FPOP) as a footprinting approach to solve diverse problems in structural biology, METHODS, 2018, 第 2 作者
（15） Laser-Initiated Radical Trifluoromethylation of Peptides and Proteins: Application to Mass-Spectrometry-Based Protein Footprinting, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 第 1 作者
（16） Gold-catalyzed Reactions of 3-Alkynyloxireno2, 3-bchromenones to Form 3(2H)-Furanones via a Domino Pathway, CHEMISTRY-AN ASIAN JOURNAL, 2013, 第 3 作者
（17） Palladium-catalyzed cascade reactions of 3-iodochromones with aryl iodides and norbornadiene leading to annulated xanthones, CHEMICAL SCIENCE, 2013, 第 1 作者
（18） Au-catalyzed cascade addition/cyclization/H-transfer reactions of 3-(1-alkynyl)chromones to construct 4H-Furo3,2-cpyrans scaffold, RSC ADVANCES, 2012, 第 4 作者
（19） Direct Synthesis of Functional Azaxanthones by Using a Domino Three-Component Reaction, ORGANIC LETTERS, 2012, 第 2 作者

（ 1 ） 新药研发案例研究, Drug Development Case Study - star drug from the laboratory to the market, 化学工业出版社, 2014-10, 第 其他 作者

   

（ 1 ） 成名课题组启动经费, 负责人, 研究所自主部署, 2024-06--2030-12

（1）Radical Trifluoromethylation: A Promising Tool for Membrane Protein Footprinting   先进质谱（生物物理以及结构生物学）   成名   2017-07-28