可编程自组装

核酸纳米技术

共振能量转移

化学

材料与化工

生物与医药

0703Z1-化学生物学
070304-物理化学
071010-生物化学与分子生物学

可编程生物纳米制造，计算机辅助纳米自组装
胶体与界面化学
时间分辨多路复用传感与成像

   

   

（1） 国家优秀自费留学奖学金, 国家级, 2019
（2） 巴黎萨克雷卓越倡议奖学金, 研究所（学校）, 2016

   

[1] Chi Chen, Xin Luo, Alexander EK Kaplan, Moungi G Bawendi, Robert J Macfarlane, Mark Bathe. Ultrafast dense DNA functionalization of quantum dots and rods for scalable 2D array fabrication with nanoscale precision. SCIENCE ADVANCES[J]. 2023, 9(32): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421044/.
[2] Wei, Xingfei, Chen, Chi, Zhao, Yinong, Harazinska, Ewa, Bathe, Mark, Hernandez, Rigoberto. Molecular Structure of Single-Stranded DNA on the ZnS Surface of Quantum Dots. ACS NANO[J]. 2022, 16(4): 6666-6675, http://dx.doi.org/10.1021/acsnano.2c01178.
[3] Chen, Chi, Wei, Xingfei, Parsons, Molly F, Guo, Jiajia, Banal, James L, Zhao, Yinong, Scott, Madelyn N, SchlauCohen, Gabriela S, Hernandez, Rigoberto, Bathe, Mark. Nanoscale 3D spatial addressing and valence control of quantum dots using wireframe DNA origami. NATURE COMMUNICATIONS[J]. 2022, 13(1): http://dx.doi.org/10.1038/s41467-022-32662-w.
[4] Chen, Chi, Hildebrandt, Niko. Resonance energy transfer to gold nanoparticles: NSET defeats FRET. TRAC-TRENDS IN ANALYTICAL CHEMISTRYnull. 2020, 123: http://dx.doi.org/10.1016/j.trac.2019.115748.
[5] Chen, Chi, Corry, Ben, Huang, Liang, Hildebrandt, Niko. FRET-Modulated Multihybrid Nanoparticles for Brightness-Equalized Single-Wavelength Barcoding. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2019, 141(28): 11123-11141, https://www.webofscience.com/wos/woscc/full-record/WOS:000476684700027.
[6] Chen, Chi, Midelet, Clyde, Bhuckory, Shashi, Hildebrandt, Niko, Werts, Martinus H V. Nanosurface Energy Transfer from Long-Lifetime Terbium Donors to Gold Nanoparticles. JOURNAL OF PHYSICAL CHEMISTRY C[J]. 2018, 122(30): 17566-17574, http://dx.doi.org/10.1021/acs.jpcc.8b06539.
[7] Chen, Chi, Ao, Lijiao, Wu, YuTang, Cifliku, Vjona, Dos Santos, Marcelina Cardoso, Bourrier, Emmanuel, Delbianco, Martina, Parker, David, Zwier, Jurriaan M, Huang, Liang, Hildebrandt, Niko. Single-Nanoparticle Cell Barcoding by Tunable FRET from Lanthanides to Quantum Dots. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2018, 57(41): 13686-13690, http://ir.siat.ac.cn:8080/handle/172644/14614.
[8] Gao, Guanhui, Chen, Chi, Xie, Xiaobin, Su, Yantao, Kang, Shendong, Zhu, Guichi, Gao, Duyang, Trampert, Achim, Cai, Lintao. Toward edges-rich MoS2 layers via chemical liquid exfoliation triggering distinctive magnetism. MATERIALS RESEARCH LETTERS[J]. 2017, 5(4): 267-275, http://dx.doi.org/10.1080/21663831.2016.1256915.
[9] Wu, Yayun, Gao, Duyang, Zhang, Pengfei, Li, Chuansheng, Wan, Qian, Chen, Chi, Gong, Ping, Gao, Guanhui, Sheng, Zonghai, Cai, Lintao. Iron oxide nanoparticles protected by NIR-active multidentate-polymers as multifunctional nanoprobes for NIRF/PA/MR trimodal imaging. NANOSCALE[J]. 2016, 8(2): 775-779, https://www.webofscience.com/wos/woscc/full-record/WOS:000367258500012.
[10] Zhang, Li, Chen, Chi, Li, Wenjun, Gao, Guanhui, Gong, Ping, Cai, Lintao. Living Cell Multilifetime Encoding Based on Lifetime-Tunable Lattice Strained Quantum Dots. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 8(21): 13187-13191, https://www.webofscience.com/wos/woscc/full-record/WOS:000377150400002.
[11] Liu, Shuhui, Zhang, Pengfei, Pan, Hong, Gao, Duyang, Chen, Chi, Zheng, Mingbin, Sheng, Zonghai, Gong, Ping, Gao, Guanhui, Wang, Hanzhong, Ma, Yifan, Cai, Lintao. QDs-virus bioconjugate as potential gene-drug co-delivery system for synergistic tumor therapy. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINEnull. 2016, 12(2): 544-544, http://dx.doi.org/10.1016/j.nano.2015.12.273.
[12] Zhang, Pengfei, Pan, Hong, Gao, Duyang, Chen, Chi, Li, Wenjun, Wu, Yayun, Hu, Dehong, Li, Chuansheng, Gong, Ping, Sheng, Zonghai, Gao, Guanhui, Ma, Yifan, Cai, Lintao. Bioorthogonal multifunctional nanoprobes for biomedicine and theranostic applications. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINEnull. 2016, 12(2): 486-486, http://dx.doi.org/10.1016/j.nano.2015.12.114.
[13] Li, Wenjun, Zheng, Cuifang, Pan, Zhengyin, Chen, Chi, Hu, Dehong, Gao, Guanhui, Kang, Shendong, Cui, Haodong, Gong, Ping, Cai, Lintao. Smart hyaluronidase-actived theranostic micelles for dual-modal imaging guided photodynamic therapy. BIOMATERIALS[J]. 2016, 101: 10-19, http://dx.doi.org/10.1016/j.biomaterials.2016.05.019.
[14] Wu, Yayun, Gao, Duyang, Zhang, Pengfei, Chen, Chi, Sheng, Zonghai, Hu, Dehong, Zheng, Mingbin, Gong, Ping, Li, Chuansheng, Gao, Guanhui, Cai, Lintao. Theranostic iron oxide nanoparticles protected by NIR-emitting multidentate-ligands for multimodal imaging-guided photothermal therapy. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINEnull. 2016, 12(2): 567-567, http://dx.doi.org/10.1016/j.nano.2015.12.336.
[15] Zheng, Mingbin, Zhao, Pengfei, Luo, Zhenyu, Gong, Ping, Gao, Guanhui, Sheng, Zonghai, Zheng, Cuifang, Chen, Chi, Ma, Yifan, Cai, Lintao. Remote and noninvasive NIR-triggered DOX release from DOX/ICG-loaded temperature-responsive nanoparticles to promote anti-tumor effect. NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINEnull. 2016, 12(2): 547-547, http://dx.doi.org/10.1016/j.nano.2015.12.282.
[16] 张利, 陈驰, 孟晓青, 吕亚琳, 周理华, 张鹏飞, 高笃阳, 盛宗海, 胡德红, 高冠慧, 易虎强, 刘朋, 龚萍, 蔡林涛. 量子点的近红外调控研究进展概述. 集成技术[J]. 2015, 17-27, http://lib.cqvip.com/Qikan/Article/Detail?id=665556345.
[17] Chen, Chi, Zhang, Pengfei, Zhang, Li, Gao, Duyang, Gao, Guanhui, Yang, Yong, Li, Wenjun, Gong, Ping, Cai, Lintao. Long-decay near-infrared-emitting doped quantum dots for lifetime-based in vivo pH imaging. CHEMICAL COMMUNICATIONS[J]. 2015, 51(56): 11162-11165, https://www.webofscience.com/wos/woscc/full-record/WOS:000357173100002.
[18] Gao, Duyang, Zhang, Pengfei, Liu, Chengbo, Chen, Chi, Gao, Guanhui, Wu, Yayun, Sheng, Zonghai, Song, Liang, Cai, Lintao. Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging. NANOSCALE[J]. 2015, 7(42): 17631-17636, https://www.webofscience.com/wos/woscc/full-record/WOS:000363650700005.
[19] Nanoscalenull. 2015, [20] Gao, Duyang, Zhang, Pengfei, Sheng, Zonghai, Hu, Dehong, Gong, Ping, Chen, Chi, Wan, Qian, Gao, Guanhui, Cai, Lintao. Highly Bright and Compact Alloyed Quantum Rods with Near Infrared Emitting: a Potential Multifunctional Nanoplatform for Multimodal Imaging In Vivo. ADVANCED FUNCTIONAL MATERIALS[J]. 2014, 24(25): 3897-3905, https://www.webofscience.com/wos/woscc/full-record/WOS:000338011200006.
[21] Wang, Yuhui, Gao, Duyang, Zhang, Pengfei, Gong, Ping, Chen, Chi, Gao, Guanhui, Cai, Lintao. A near infrared fluorescence resonance energy transfer based aptamer biosensor for insulin detection in human plasma. CHEMICAL COMMUNICATIONS[J]. 2014, 50(7): 811-813, https://www.webofscience.com/wos/woscc/full-record/WOS:000328884500013.
[22] Chen, Chi, Zhang, Pengfei, Gao, Guanhui, Gao, Duyang, Yang, Yong, Liu, Hong, Wang, Yuhui, Gong, Ping, Cai, Lintao. Near-Infrared-Emitting Two-Dimensional Codes Based on Lattice-Strained Core/(Doped) Shell Quantum Dots with Long Fluorescence Lifetime. ADVANCED MATERIALS[J]. 2014, 26(36): 6313-6317, https://www.webofscience.com/wos/woscc/full-record/WOS:000342622700014.
[23] Chen, Chi, He, Xuewen, Gao, Li, Ma, Nan. Cation Exchange-Based Facile Aqueous Synthesis of Small, Stable, and Nontoxic Near-Infrared Ag2Te/ZnS Core/Shell Quantum Dots Emitting in the Second Biological Window. ACS APPLIED MATERIALS & INTERFACES[J]. 2013, 5(3): 1149-1155, https://www.webofscience.com/wos/woscc/full-record/WOS:000315079700091.
[24] Ding, Ling, Zhou, Peijiang, Zhan, Hongju, Zhao, Xiaohu, Chen, Chi, He, Zhenyu. Systematic investigation of the toxicity interaction of ZnSe@ZnS QDs on BSA by spectroscopic and microcalorimetry techniques. CHEMOSPHERE[J]. 2013, 92(8): 892-897, http://dx.doi.org/10.1016/j.chemosphere.2013.02.045.
[25] Ding, Ling, Zhou, PeiJiang, Zhan, HongJu, Chen, Chi, Hu, Wei, Zhou, TengFei, Lin, ChaoWang. Microwave-assisted synthesis of L-glutathione capped ZnSe QDs and its interaction with BSA by spectroscopy. JOURNAL OF LUMINESCENCE[J]. 2013, 142: 167-172, http://dx.doi.org/10.1016/j.jlumin.2013.04.008.
[26] Ma, Rong, Zhou, PeiJiang, Zhan, HongJu, Chen, Chi, He, YuNing. Optimization of microwave-assisted synthesis of high-quality ZnSe/ZnS core/shell quantum dots using response surface methodology. OPTICS COMMUNICATIONS[J]. 2013, 291: 476-481, http://dx.doi.org/10.1016/j.optcom.2012.11.030.

   

（1）Programmable nanoscale assembly of quantum dots and rods using wireframe DNA origami   Chi Chen   2024-03-15
（2）Wireframe DNA Origami enabled Valence-Geocoded Nanoparticles for FRET-Modulated Fluorescence Multiplexing   Chi Chen   2023-03-21
（3）Live-Cell Encoding by Single-Nanoparticle FRET Multiplexing   Chi Chen   2019-04-01
（4）Particle Encoding using Terbium-to-Quantum Dot FRET   Chi Chen   2018-06-12