070302-分析化学
0703Z1-化学生物学

动态核极化增强固体核磁共振的方法与应用
GPCR分子机制与药物开发

   

（1） Molecular mechanisms and evolutionary robustness of a color switch in proteorhodopsins, Science Advances, 2024, 
（2） Room-temperature dynamic nuclear polarization enhanced NMR spectroscopy of small biological molecules in water, Nature Communications, 2021, 
（3） Cysteine oxidation and disulfide formation in the ribosomal exit tunnel, Nature Communications, 2020, 第 1 作者
（4） Light Dynamics of the Retinal���Disease���Relevant G90D Bovine Rhodopsin Mutant, Angewandte Chemie, 2020, 第 1 作者
（5） Exploring Protein Structures by DNPEnhanced Methyl Solid-State NMR Spectroscopy, Journal of the American Chemical Society, 2019, 
（6） The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors, Nature Chemical Biology, 2018, 第 1 作者
（7） Antigenic Peptide Recognition on the Human ABC Transporter TAP Resolved by DNPEnhanced Solid-State NMR Spectroscopy, Journal of the American Chemical Society, 2016, 第 1 作者
（8） Structural Basis of the Green���Blue Color Switching in Proteorhodopsin as Determined by NMR Spectroscopy, Journal of the American Chemical Society, 2014, 第 1 作者
（9） Host���Guest Complexes as Water- Soluble High-Performance DNP Polarizing Agents, Journal of the American Chemical Society, 2013, 第 1 作者

   

（1）Allosteric ligands induce structural diversity of orthosteric peptide agonist in human bradykinin 1 receptor   2023-06-14
（2）Liquid-state DNP NMR spectroscopy of biological molecules in water   2023-05-20
（3）Room-Temperature DNP NMR spectroscopy of small biological molecules in water   2021-07-15
（4）Decoding GPCR Functions by Sensitivity-Enhanced Solid-State NMR Spectroscopy   2019-05-21
（5）Understanding Ligand Selectivity of GPCR Subtypes – A View of Peptide Ligands from SSNMR Spectroscopy Enhanced by DNP   2016-02-18