基本信息

李建戌 男 硕导 中国科学院分子植物科学卓越创新中心
电子邮件: lijx@cemps.ac.cn
通信地址: 上海市松江区辰花路3888号辰山科研中心228
邮政编码:
电子邮件: lijx@cemps.ac.cn
通信地址: 上海市松江区辰花路3888号辰山科研中心228
邮政编码:
招生信息
招生专业
071300-生态学071001-植物学071010-生物化学与分子生物学
招生方向
植物代谢与结构生物学代谢酶的工程改造
教育背景
2005-09--2012-07 中国科学院上海生命科学研究院植物生理生态研究所 博士研究生2001-09--2005-07 山东师范大学 本科,学士
工作经历
工作简历
2023-04~现在, 中国科学院分子植物科学卓越创新中心辰山科学研究中心, 副研究员,青年研究组长2020-05~2023-03,中国科学院分子植物科学卓越创新中心, 副研究员2017-12~2020-04,中国科学院上海生命科学研究院植物生理生态研究所, 副研究员2015-11~2017-11,中国科学院上海生命科学研究院植物生理生态研究所, 助理研究员2013-06~2015-10,中国科学院上海生命科学研究院植物生理生态研究所, 博士后2012-06~2013-05,美国加州大学伯克利分校, 博士后2005-09~2012-07,中国科学院上海生命科学研究院植物生理生态研究所, 博士研究生2001-09~2005-07,山东师范大学, 本科,学士
专利与奖励
奖励信息
(1) 上海市东方英才计划青年项目, 省级, 2023(2) 赛诺菲-中国科学院上海生命科学研究院优秀青年人才奖, 院级, 2018
专利成果
( 1 ) 糖基转移酶突变体及其应用, 2023, 第 6 作者, 专利号: CN112080480B( 2 ) 一种新的倍半萜合成酶及其用途, 2013, 第 3 作者, 专利号: CN103243083A( 3 ) 一种酶活性提高的青蒿紫穗槐二烯合酶突变体及其应用, 2012, 第 2 作者, 专利号: CN102732499A
出版信息
发表论文
(1) A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids, Plant Physiology, 2022, 第 5 作者(2) Two types of O-methyltransferase are involved in biosynthesis of anticancer methoxylated 4 '-deoxyflavones in Scutellaria baicalensis Georgi, PLANTBIOTECHNOLOGYJOURNAL, 2022, 第 3 作者(3) Molecular and structural characterization of a promiscuous chalcone synthase from the fern species Stenoloma chusanum, Molecular and structural characterization of a promiscuous chalcone synthase from the fern species Stenoloma chusanum, Journal of Integrative Plant Biology, 2022, 第 9 作者 通讯作者(4) Functional and Structural Investigation of Chalcone Synthases Based on Integrated Metabolomics and Transcriptome Analysis on Flavonoids and Anthocyanins Biosynthesis of the Fern Cyclosorus parasiticus, FRONTIERS IN PLANT SCIENCE, 2021, 第 8 作者 通讯作者(5) Structural insights into phospholipase D function, PROGRESS IN LIPID RESEARCH, 2021, 第 2 作者(6) A unique flavoenzyme operates in ubiquinone biosynthesis in photosynthesis-related eukaryotes, SCIENCE ADVANCES, 2021, 第 5 作者(7) 1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue, ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 第 3 作者(8) Structural and Biochemical Insights Into Two BAHD Acyltransferases (AtSHT and AtSDT) Involved in Phenolamide Biosynthesis, FRONTIERS IN PLANT SCIENCE, 2021, 第 2 作者(9) Occurrence and biosynthesis of plant sesterterpenes (C25), a new addition to terpene diversity, Occurrence and biosynthesis of plant sesterterpenes (C25), a new addition to terpene diversity, PLANT COMMUNICATIONS, 2021, 第 2 作者(10) Aromatization of natural products by a specialized detoxification enzyme, NATURE CHEMICAL BIOLOGY, 2020, 第 7 作者(11) Crystal structure of plant PLDα1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D, Crystal structure of plant PLD��1 reveals catalytic and regulatory mechanisms of eukaryotic phospholipase D, 细胞研究:英文版, 2020, 第 1 作者(12) Molecular Basis for Sesterterpene Diversity Produced by Plant Terpene Synthases, PLANT COMMUNICATIONS, 2020, 第 2 作者(13) Structural Insights into the CatalyticMechanism of a Plant Diterpene Glycosyltransferase SrUGT76G1, Structural Insights into the Catalytic Mechanism of a Plant Diterpene Glycosyltransferase SrUGT76G1, PLANT COMMUNICATIONS, 2020, 第 2 作者(14) Diterpenoid UDP-Glycosyltransferases from Chinese Sweet Tea and Ashitaba Complete the Biosynthesis of Rubusoside, MOLECULAR PLANT, 2018, 第 3 作者(15) Systematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase, BIOCHEMICAL JOURNAL, 2017, 第 2 作者(16) Molecular mechanism of environmental d -xylose perception by a XylFII-LytS complex in bacteria, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 第 1 作者(17) Isolation and Characterization of Three New Monoterpene Synthases from Artemisia annua, FRONTIERS IN PLANT SCIENCE, 2016, 第 2 作者(18) Structural Analyses of Short-Chain Prenyltransferases Identify an Evolutionarily Conserved GFPPS Clade in Brassicaceae Plants., MOLECULAR PLANT, 2016, 第 4 作者(19) Isolation and characterization of AaAER, a novel double bond reductase from Artemisia annua, JOURNAL OF PLANT BIOCHEMISTRY AND BIOTECHNOLOGY, 2015, 第 2 作者(20) Structural basis of intramitochondrial phosphatidic acid transport mediated by Ups1-Mdm35 complex, EMBO REPORTS, 2015, 第 6 作者(21) ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes, NATURE, 2015, 第 9 作者(22) Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency, BIOCHEMICAL JOURNAL, 2013, 第 1 作者(23) 植物萜类次生代谢及其调控, Biosynthesis and Regulation of Secondary Terpenoid Metabolism in Plants, 中国科学. 生命科学, 2013, 第 4 作者(24) The Jasmonate-Responsive AP2/ERF Transcription Factors AaERF1 and AaERF2 Positively Regulate Artemisinin Biosynthesis in Artemisia annua L., The Jasmonate-Responsive AP2/ERF Transcription Factors AaERF1 and AaERF2 Positively Regulate Artemisinin Biosynthesis in Artemisia annua L., MOLECULAR PLANT, 2012, 第 2 作者(25) Increased Accumulation of Artemisinin and Anthocyanins in Artemisia annua Expressing the Arabidopsis Blue Light Receptor CRY1, PLANT MOLECULAR BIOLOGY REPORTER, 2009, 第 3 作者(26) The rice ( E)-��-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes, PHYTOCHEMISTRY, 2007, 第 3 作者
科研活动
科研项目
( 1 ) 叶绿素的合成及调控机制, 负责人, 研究所自主部署, 2024-01--2026-06( 2 ) 叶绿素的合成与调控机制, 负责人, 地方任务, 2023-12--2026-12( 3 ) 植物蓝光受体的结构与信号传递机制, 参与, 国家任务, 2023-01--2027-12
参与会议
(1)Structure and Mechanism of Eukaryotic Phospholipase D 中国晶体学会第八届学术年会 2021-10-21(2)Structure and Mechanism of Eukaryotic Phospholipase D 第六届华东地区结构生物学会议 2019-10-26