General

Tan Xiaotian, Associate Professor

Shenzhen Institutes of Advanced Technology

Ph.D. in Biomedical Engineering

Research focuses on the development of biomolecular sensing technologies 

Research Areas

1. Biosensor design and development, especially for immunosensing

2. Bio-laser for biomolecular sensing

3. AI-assisted rational design of protein immunoassay probes (Sensobody)

4. Disease control and diagnosis approaches using microliter-volumed fingertip blood

Education

2015-2020 University of Michigan, Biomedical Engineering, Ph.D., M.S.

2011-2015 New York Univerisity, Chemical and Biomolecular Engineering, B.S.

Publications

  • A Quantitative First Passage Time Model for Tubular Microfluidic Immunoassays
    ACS Sensors, January 2025
    The paper introduces a quantitative model based on first passage time for analyzing tubular microfluidic immunoassays, enhancing the understanding of analyte transport dynamics.

  • Consolidated Microscale Interferon-γ Release Assay with Tip Optofluidic Immunoassay for Dynamic Parallel Diagnosis of Tuberculosis Infection
    Analytical Chemistry, Febuary 2025.
    This study reports the development of a tip optofluidic immunoassay (TOI)-based consolidated microscale IGRA (CM-IGRA) for the dynamic and parallel evaluation of TB infection.

  • Tip Optofluidic Immunoassay: Evaluating COVID-19 Antibody Protection with 1μL Fingertip Blood
    hLife, June 2025.
    This study introduces a novel optofluidic biosensing technology, tip optofluidic immunoassay (TOI), that addresses limitations by enabling the quantitative analysis of binding and neutralizing antibodies against multiple SARS-CoV-2 strains from only 1 μL of fingertip blood.


Papers