071005-微生物学

植物天然产物异源生物合成
酿酒酵母代谢改造

2009-09--2015-06   南开大学   理学博士
2005-09--2009-06   天津师范大学   理学学士

   

2022-10~现在, 中国科学院青岛生物能源与过程研究所, 研究员
2015-09~2020-06,查尔姆斯理工大学（瑞典）, 博士后
2009-09~2015-06,南开大学, 理学博士
2005-09~2009-06,天津师范大学, 理学学士

2023-01-11-今,中国生物工程学会会员,

   

（1） Metabolic reconfiguration enables synthetic reductive metabolism in yeast, NATURE METABOLISM, 2022, 第 2 作者
（2） Metabolic network remodelling enhances yeast's fitness on xylose using aerobic glycolysis, NATURE CATALYSIS, 2021, 第 4 作者
（3） De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories, NATURE COMMUNICATIONS, 2021, 第 1 作者
（4） Current state of aromatics production using yeast: achievements and challenges, CURRENT OPINION IN BIOTECHNOLOGY, 2020, 第 1 作者
（5） RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 第 4 作者
（6） Rewiring carbon metabolism in yeast for high level production of aromatic chemicals, NATURE COMMUNICATIONS, 2019, 第 1 作者
（7） 双孢蘑菇酪氨酸酶基因在酿酒酵母中的异源表达及其酶学特性, Expression and characterization of tyrosinase from Agaricus bisporus in Saccharomyces cerevisiae, 微生物学报, 2018, 第 3 作者
（8） Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis, CELL, 2018, 第 4 作者
（9） Metabolic engineering strategies for improvement of ethanol production in cellulolytic Saccharomyces cerevisiae, FEMS YEAST RESEARCH, 2018, 第 5 作者
（10） Modular Pathway Rewiring of Yeast for Amino Acid Production, ENZYMES IN SYNTHETIC BIOLOGY, 2018, 第 1 作者
（11） A high-throughput method for screening of L-tyrosine high-yield strains by Saccharomyces cerevisiae, JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY, 2018, 第 2 作者
（12） Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals, NATURE COMMUNICATIONS, 2017, 第 4 作者
（13） Scarless gene deletion using mazF as a new counter-selection marker and an improved deletion cassette assembly method in Saccharomyces cerevisiae, JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY, 2014, 第 1 作者
（14） mazF-mediated deletion system for large-scale genome engineering in Saccharomyces cerevisiae, RESEARCH IN MICROBIOLOGY, 2014, 第 1 作者
（15） Identification of the bacteriocin subtilosin A and loss of purL results in its high-level production in Bacillus amyloliquefaciens, RESEARCH IN MICROBIOLOGY, 2012, 第 1 作者
（16） CitB mutation increases the alkaline protease productivity in Bacillus subtilis, JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY, 2010, 第 3 作者

   

（ 1 ） 模块化重塑酿酒酵母底盘高效合成植物生物碱, 负责人, 国家任务, 2023-10--2026-12
（ 2 ） 芳香氨基酸高效底盘细胞的重构与拓展, 负责人, 地方任务, 2022-07--2025-06