基本信息

陈凯凯  男 纳米科学与工程学院

电子邮件: chenkaikai(at)ucas.ac.cn

通信地址:北京市怀柔区雁栖湖东路1号 中国科学院大学雁栖湖校区东区 学园四401

邮政编码:101408

研究领域

具体内容见:https://sites.google.com/view/kaikaichen

软凝聚态与生物物理、纳米科学与技术、物理化学

陈凯凯于2023年1月加入中国科学院大学纳米学院担任副教授、特别研究员。陈凯凯于2017年在清华大学获得博士学位,导师为田煜教授,2017.08-2022.12在剑桥大学物理系(卡文迪许实验室)从事博士后研究,合作导师为Ulrich F. Keyser,目前已在Nature PhysicsNature NanotechnologyNature Biomedical EngineeringNature CommunicationsAdvanced MaterialsACS NanoNano Letters等期刊发表论文20余篇,相关研究成果被Phys.org、Nanowerk、Scienmag、Bioengineer.org等报道。2022年入选国家海外高层次青年人才项目和中国科学院“****”项目。

招生及招聘信息

招聘详情:

https://talent.sciencenet.cn/index.php?s=Info/index/id/23238

http://muchong.com/t-15479944-1

课题组每年招收博士生及硕士生,目前正在招聘副研究员、助理研究员、博士后/特别研究助理、科研助理和联合培养研究生,每年接受推免生报名,欢迎具有物理、化学等学科背景的优秀学生加入。实验室经费充足,可支持开展大多数科研创新工作。同时,实验室支持成员申请国家、中科院和中国科学院大学的各类人才项目以及赴国外交流学习。有意加入课题组,请将个人材料发送至邮箱chenkaikai(at)ucas.ac.cn (请将(at)换成@)。

教育背景

2014-09--2017-06   清华大学   博士
2011-09--2014-06   中国石油大学   硕士
2007-09--2011-06   中国石油大学   学士

工作经历

2023.01至今              中国科学院大学 纳米科学与工程学院 副教授

2017.08 - 2022.12     剑桥大学物理系 卡文迪许实验室 博士后

出版信息

29.   S. Sandler, N. E. Weckman, S. Yorke, A. Das, K. Chen, R. Guitterez, and U. F. Keyser. 

Sensing the DNA-mismatch tolerance of catalytically inactive Cas9 via barcoded DNA nanostructures in solid-state nanopores

Nature Biomedical Engineering 2024, 8, 325.


28. F. Zheng, M. Alawami, J. Zhu, C. M. Platnich, J. Sha, U. F. Keyser,* and K. Chen*

DNA Carrier-Assisted Molecular Ping-Pong in an Asymmetric Nanopore

Nano Letters 2023, 23, 11145-11151.


27.   S. M. Leitao, V. Navikas, H. Miljkovic, B. Drake, S. Marion, G. Pistoletti, K. Chen, S. Mayer, U. F. Keyser, A. Kuhn, G. E. Fantner, and A. Radenovic. 

Spatially Multiplexed Single-molecule Translocations through a Nanopore at Controlled Speeds.

Nature Nanotechnology 2023, 18, 1078.


26.    F. Boskovic, J. Zhu, R. Tivony, A. Ohmann, K. Chen, M. Alawami, M. Đorđević, N. Ermann, J. Pereira-Dias, M. Fairhead, M. Howarth, S. Baker, and U. F. Keyser. 

Simultaneous identification of viruses and viral variants with programmable DNA nanobait.

Nature Nanotechnology 2023, 18, 290-298. 


25.    K. Chen, A. Choudhary, S. E. Sandler, C. Maffeo, C. Ducati, A. Aksimentiev, and U. F. Keyser. 

Super-resolution detection of DNA nanostructures using a nanopore

Advanced Materials 2023, 2207434. 


24.    A.F. Mohammed, F. Bošković, J. Zhu, K. Chen, S.E. Sandler, and U. F. Keyser. 

Lifetime of glass nanopores in a PDMS chip for single-molecule sensing. 

iScience 2022, 25, 104191. 


23.    K. Chen, I. Jou, N. Ermann, M. Muthukumar, U. F. Keyser, and N. A. W. Bell. 

Dynamics of driven polymer transport through a nanopore. 

Nature Physics 2021, 17, 1043-1049. 


22.    J. Zhu, J., N. Ermann, K. Chen, and U. F. Keyser. 

Image encoding using multi-Level DNA barcodes with nanopore readout. 

Small 2021, 2100711. 


21.    F. Boskovic, A. Ohmann, U. F. Keyser*, and K. Chen*.

DNA structural barcode copying and random access. 

Small Structures 2021, 2000144. 


20.    K. Chen, F. Gularek, B. Liu, E. Weinhold, and U. F. Keyser. 

Electrical DNA sequence mapping using oligodeoxynucleotide labels and nanopores. 

ACS Nano 2021, 15, 2679-2685. 


19.    K. Chen, J. Zhu, F. Bošković, and U. F. Keyser. 

Nanopore-based DNA hard drives for rewritable and secure data storage. 

Nano Letters 2020, 20, 3754-3760. 


18.    N. E. Weckman, N. Ermann, R. Gutierrez, K. Chen, J. Graham, A. Heron, and U. F. Keyser. 

Pushing the resolution of dCas9 barcodes for multiplexed DNA identification with nanopore sensors

IEEE Sensors 2019


17.    F. Boskovic, J. Zhu, K. Chen, and U. F. Keyser. 

Monitoring G-quadruplex formation with DNA carriers and solid-state nanopores. 

Nano Letters 2019, 19, 7996-8001.


16.    N. E. Weckman, N. Ermann, R. Gutierrez, K. Chen, J. Graham, R. Tivony, A. Heron, and U. F. Keyser. 

Multiplexed DNA identification using site specific dCas9 barcodes and nanopore sensing. 

ACS Sensors 2019, 4, 2065-2072. 


15.    K. Chen, J. Kong, J. Zhu, N. Ermann, P. Predki, and U. F. Keyser. 

Digital data storage using DNA nanostructures and solid-state nanopores. 

Nano Letters 2019, 19, 1210-1215. 


14.    J. Kong, J. Zhu, K. Chen, and U. F. Keyser. 

Specific biosensing using DNA aptamers and nanopores. 

Advanced Functional Materials 2018, 1807555.


13.    N. Ermann, N. Hanikel, V. Wang, K. Chen, N. E. Weckman, and U. F. Keyser. 

Promoting single-file DNA translocations through nanopores using electro-osmotic flow. 

The Journal of Chemical Physics 2018, 149, 163311. 


12.    M. Zhou*. K. Chen*. X. Li, L. Liu, Q. Zeng, Y. Mo, L. Jin, L. Li, G. Su, J. Che, and Y. Tian* .

Clumping stability of vertical nanofibers on surfaces. 

Langmuir 2018, 34, 11629-11636. 


11.    N. A. W. Bell#K. Chen#, S. Ghosal, M. Ricci, and U. F. Keyser. 

Asymmetric dynamics of DNA entering and exiting a strongly confining nanopore. 

Nature Communications 2017, 8, 380. 


10.    K. Chen, M. Juhasz, F. Gularek, E. Weinhold, Y. Tian, U. F. Keyser, and N. A. W. Bell. 

Ionic current-based mapping of short sequence motifs in single DNA molecules using solid-state nanopores. 

Nano Letters 2017, 17, 5199-5205.


9.      K. Chen, N. A. W. Bell, J. Kong, Y. Tian, and U. F. Keyser. 

Direction- and salt-dependent ionic current signatures for DNA sensing with asymmetric nanopores. 

Biophysical Journal 2017, 112, 674-682. 


Before 2017

8.      C. Xue, X. Zheng, K. Chen, Y. Tian, and G. Hu. Probing non-gaussianity in confined diffusion of nanoparticles. The Journal of Physical Chemistry Letters 2016, 7, 514-9. 

7.      L. Shan, K. Chen, M. Zhou, X. Zhang, Y. Meng, and Y. Tian. Shear history effect of magnetorheological fluids. Smart Materials and Structures 2015, 24, 105030. 

6.      K. Chen, L. Shan, S. He, G. Hu, Y. Meng, and Y. Tian. Biphasic resistive pulses and ion concentration modulation during particle translocation through cylindrical nanopores. The Journal of Physical Chemistry C 2015, 119, 8329-8335. 

5.      K. Chen, W. L. Zhang, L. Shan, X. Zhang, Y. Meng, H. J. Choi, and Y. Tian. Magnetorheology of suspensions based on graphene oxide coated or added carbonyl iron microspheres and sunflower oil. Journal of Applied Physics 2014, 116, 153508. 

4.      K. Chen, Y. Tian, L. Shan, X. Zhang, and Y. Meng. Squeeze behaviors of magnetic powders between two parallel plates. Smart Materials and Structures 2014, 23, 117004. 

3.      Y. Tian, K. Chen, L. Shan, X. Zhang, and Y. Meng. Unexpected shear strength change in magnetorheological fluids. APL Materials 2014, 2, 096102. 

2.      K. Chen, Y. Tian, L. Shan, X. Zhang, and Y. Meng. The rheological properties of magnetic field excited magnetic powders sheared between two parallel plates. Smart Materials and Structures 2013, 22, 115036. 

1.      K. Chen, Y. Tian, L. Shan, and J. Jiang. Transient response of sheared magnetic powder excited by a stepwise magnetic field and its comparison with ER and MR fluids. Smart Materials and Structures 2013, 22, 097001.