基本信息
俞淼荣 男 硕导 中国科学院上海药物研究所
电子邮件: mryu@simm.ac.cn
通信地址: 上海市浦东新区海科路501号
邮政编码:
电子邮件: mryu@simm.ac.cn
通信地址: 上海市浦东新区海科路501号
邮政编码:
招生信息
招生专业
100702-药剂学
招生方向
药物载体;LNP
教育背景
2012-09--2017-06 中国科学院上海药物研究所 博士2008-09--2012-06 沈阳药科大学 本科
工作经历
工作简历
2019-10~现在, 中国科学院上海药物研究所, 副研究员2017-07~2019-09,中国科学院上海药物研究所, 助理研究员2012-09~2017-06,中国科学院上海药物研究所, 博士2008-09~2012-06,沈阳药科大学, 本科
社会兼职
2022-01-01-今,Chinese Chemical Letters杂志青年编委,
教授课程
中药药剂学专论高等药剂学选论
专利与奖励
奖励信息
(1) 上海药物研究所“优秀共产党员”, 研究所(学校), 2021(2) 上海药物研究所“优秀青年科技工作者”, 研究所(学校), 2019
专利成果
( 1 ) 一种控释给药的药芯组合物以及包含该药芯组合物的渗透泵制剂, 2020, 第 5 作者, 专利号: CN104857515B( 2 ) 动态监控的高频超声雾化微粒制备系统, 2016, 第 5 作者, 专利号: CN105582683A
出版信息
发表论文
(1) Dual-modified nanoparticles overcome sequential absorption barriers for oral insulin delivery, JOURNAL OF CONTROLLED RELEASE, 2022, 第 11 作者(2) The upregulated intestinal folate transporters direct the uptake of ligand-modified nanoparticles for enhanced oral insulin delivery, ACTA PHARMACEUTICA SINICA B, 2022, 第 3 作者(3) Engineering nanoparticles to overcome the mucus barrier for drug delivery: Design, evaluation and state-of-the-art, Medicine in Drug Discovery, 2021, 第 11 作者(4) Liver-Target and Glucose-Responsive Polymersomes toward Mimicking Endogenous Insulin Secretion with Improved Hepatic Glucose Utilization, ADVANCED FUNCTIONAL MATERIALS, 2020, 第 6 作者(5) MT1���MMP���Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy, ADVANCED SCIENCE, 2020, 第 13 作者(6) Cancer-Cell-Membrane-Coated Nanoparticles with a Yolk-Shell Structure Augment Cancer Chemotherapy, NANO LETTERS, 2020, 第 13 作者(7) Smart Tumor Microenvironment-Responsive Nanotheranostic Agent for Effective Cancer Therapy, ADVANCED FUNCTIONAL MATERIALS, 2020, 第 4 作者(8) Rapid transport of germ-mimetic nanoparticles with dual conformational polyethylene glycol chains in biological tissues, SCIENCE ADVANCES, 2020, 第 6 作者(9) Cancer Cell Membrane-Camouflaged Nanorods with Endoplasmic Reticulum Targeting for Improved Antitumor Therapy, ACS APPLIED MATERIALS & INTERFACES, 2019, 第 2 作者(10) Chain-Length- and Saturation-Tuned Mechanics of Fluid Nanovesicles Direct Tumor Delivery, ACS NANO, 2019, 第 2 作者(11) Cholesterol-tuned liposomal membrane rigidity directs tumor penetration and anti-tumor effect, ACTA PHARMACEUTICA SINICA B, 2019, 第 2 作者(12) Advances in particle shape engineering for improved drug delivery, DRUG DISCOVERY TODAY, 2019, 第 4 作者(13) Npc1l1-targeted cholesterol-grafted poly(��-amino ester)/pdna complexes for oral gene delivery, Advanced healthcare materials, 2019, 第 5 作者(14) Temperature- and rigidity-mediated rapid transport of lipid nanovesicles in hydrogels, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 第 1 作者(15) Rapid transport of deformation-tuned nanoparticles across biological hydrogels and cellular barriers, NATURE COMMUNICATIONS, 2018, 第 1 作者(16) Diffusion of rod-like nanoparticles in non-adhesive and adhesive porous polymeric gels, JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS, 2018, 第 3 作者(17) Enhanced digestion inhibition and mucus penetration of F127-modified self-nanoemulsions for improved oral delivery, Enhanced digestion inhibition and mucus penetration of F127-modified self-nanoemulsions for improved oral delivery, 亚洲药物制剂科学(英文), 2018, 第 3 作者(18) Rotation-Facilitated Rapid Transport of Nanorods in Mucosal Tissues, NANO LETTERS, 2016, 第 1 作者(19) Advances in the transepithelial transport of nanoparticles, DRUG DISCOVERY TODAY, 2016, 第 1 作者(20) poly-L-glutamic acid functionalized nanocomplex for improved oral drug absorption, JOURNAL OF MATERIALS CHEMISTRY B, 2015, 第 5 作者
科研活动
科研项目
( 1 ) 新星项目A类, 负责人, 研究所自主部署, 2022-01--2024-12( 2 ) 刚度效应对口服纳米药物载体克服胃肠道吸收屏障的影响及微观机制的研究, 负责人, 国家任务, 2021-01--2024-12( 3 ) Liver-targeted and glucose-responsive smart insulin nanocarriers to improve diabetes treatment, 负责人, 中国科学院计划, 2020-01--2021-12( 4 ) 基于人工智能技术的高效口服递药载体的形状设计及其提高药物吸收机制的研究, 负责人, 国家任务, 2019-01--2021-12