083100-生物医学工程
080502-材料学
0710J6-再生医学

类器官；生物材料；器官芯片；组织工程

2006-04--2009-04   日本筑波大学   博士研究生毕业，博士学位
2002-09--2006-01   中国海洋大学   硕士研究生毕业，硕士学位
1998-09--2002-06   中国海洋大学   本科毕业学士学位

   

2022-05~现在, 中国科学院上海硅酸盐研究所, 特聘研究员，独立PI
2019-01~2022-04,悉尼科技大学, 研究员
2015-06~2018-12,澳大利亚新南威尔士大学, 研究员
2012-04~2015-05,澳大利亚新南威尔士大学, 博士后
2009-05~2012-03,日本国立物质材料研究所, 博士后

Molecular Nanotechnology

   

（1） 澳大利亚研究理事会优秀青年研究员, , 国家级, 2015
（2） 日本再生医疗学会优秀青年研究者, 其他, 2012
（3） 国际再生医疗材料研讨会（中国台湾）优秀青年研究者, 其他, 2010

   

[1] Zhang, Qianyi, Zhou, Dandan, Fang, Guocheng, Lu, Hongxu, Zeng, Jianfeng, Gu, Zi. Cell-Derived Biomimetic 2D Nanoparticles to Improve Cell-Specific Targeting and Tissue Penetration for Enhanced Magnetic Resonance Imaging. ADVANCED MATERIALS INTERFACES[J]. 2022, 9(7): [2] Fang, Guocheng, Lu, Hongxu, AlNakashli, Russul, Chapman, Robert, Zhang, Yingqi, Ju, Lining Arnold, Lin, Gungun, Stenzel, Martina H, Jin, Dayong. Enabling peristalsis of human colon tumor organoids on microfluidic chips. BIOFABRICATION[J]. 2022, 14(1): http://dx.doi.org/10.1088/1758-5090/ac2ef9.
[3] Yingqi Zhang, Savindi De Zoysa Ramasundara, Renee Ellen Preketestardiani, Vivian Cheng, Hongxu Lu, Lining Arnold Ju. Emerging Microfluidic Approaches for Platelet Mechanobiology and Interplay With Circulatory Systems. Frontiers in Cardiovascular Medicine. 2021, 8: [4] AlNakashli, Russul, Oh, Hongji, Chapman, Robert, Stenzel, Martina H, Lu, Hongxu. Regulating the uptake of poly(N-(2-hydroxypropyl) methacrylamide)-based micelles in cells cultured on micropatterned surfaces. BIOINTERPHASES[J]. 2021, 16(4): http://dx.doi.org/10.1116/6.0001012.
[5] Fang, Guocheng, Lu, Hongxu, Es, Hamidreza Aboulkheyr, Wang, Dejiang, Liu, Yuan, Warkiani, Majid Ebrahimi, Lin, Gungun, Jin, Dayong. Unidirectional intercellular communication on a microfluidic chip. BIOSENSORS & BIOELECTRONICS[J]. 2021, 175: http://dx.doi.org/10.1016/j.bios.2020.112833.
[6] Fang, Guocheng, Lu, Hongxu, Rodriguez de la Fuente, Laura, Law, Andrew M K, Lin, Gungun, Jin, Dayong, GallegoOrtega, David. Mammary Tumor Organoid Culture in Non-Adhesive Alginate for Luminal Mechanics and High-Throughput Drug Screening. ADVANCED SCIENCE[J]. 2021, 8(21): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000693659800001.
[7] Lu, Hongxu, Su, Jiaying, Mamdooh, Russul, Li, Yimeng, Stenzel, Martina H. Cellular Uptake of Gold Nanoparticles and Their Movement in 3D Multicellular Tumor Spheroids: Effect of Molecular Weight and Grafting Density of Poly(2-hydroxyl ethyl acrylate). MACROMOLECULAR BIOSCIENCE[J]. 2020, 20(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000501474600001.
[8] Fang, Guocheng, Lu, Hongxu, Law, Andrew, GallegoOrtega, David, Jin, Dayong, Lin, Gungun. Gradient-sized control of tumor spheroids on a single chip. LAB ON A CHIP[J]. 2019, 19(24): 4093-4103, http://dx.doi.org/10.1039/c9lc00872a.
[9] Lu, Hongxu, Stenzel, Martina H. Multicellular Tumor Spheroids (MCTS) as a 3D In Vitro Evaluation Tool of Nanoparticles. SMALL[J]. 2018, 14(13): https://www.webofscience.com/wos/woscc/full-record/WOS:000428797800001.
[10] Lu, Hongxu, Noorani, Lubna, Jiang, Yanyan, Du, Alice W, Stenzel, Martina H. Penetration and drug delivery of albumin nanoparticles into pancreatic multicellular tumor spheroids. JOURNAL OF MATERIALS CHEMISTRY B[J]. 2017, 5(48): 9591-9599, [11] Lu, Hongxu, Blunden, Bianca M, Scarano, Wei, Lu, Mingxia, Stenzel, Martina H. Anti-metastatic effects of RAPTA-C conjugated polymeric micelles on two-dimensional (2D) breast tumor cells and three-dimensional (3D) multicellular tumor spheroids. ACTA BIOMATERIALIA[J]. 2016, 32: 68-76, http://dx.doi.org/10.1016/j.actbio.2015.12.020.
[12] Lu, Hongxu, Utama, Robert H, Kitiyotsawat, Uraiphan, Babiuch, Krzysztof, Jiang, Yanyan, Stenzel, Martina H. Enhanced transcellular penetration and drug delivery by crosslinked polymeric micelles into pancreatic multicellular tumor spheroids. BIOMATERIALS SCIENCE[J]. 2015, 3(7): 1085-1095, https://www.webofscience.com/wos/woscc/full-record/WOS:000356309200016.
[13] Zhai, Wanyin, Lu, Hongxu, Wu, Chengtie, Chen, Lei, Lin, Xiaoting, Naoki, Kawazoe, Chen, Guoping, Chang, Jiang. Stimulatory effects of the ionic products from Ca-Mg-Si bioceramics on both osteogenesis and angiogenesis in vitro. ACTA BIOMATERIALIA[J]. 2013, 9(8): 8004-8014, http://dx.doi.org/10.1016/j.actbio.2013.04.024.
[14] Lu, Hongxu, Kawazoe, Naoki, Kitajima, Takashi, Myoken, Yuka, Tomita, Masahiro, Umezawa, Akihiro, Chen, Guoping, Ito, Yoshihiro. Spatial immobilization of bone morphogenetic protein-4 in a collagen-PLGA hybrid scaffold for enhanced osteoinductivity. BIOMATERIALS[J]. 2012, 33(26): 6140-6146, http://dx.doi.org/10.1016/j.biomaterials.2012.05.038.
[15] Zhai, Wanyin, Lu, Hongxu, Chen, Lei, Lin, Xiaoting, Huang, Yan, Dai, Kerong, Naoki, Kawazoe, Chen, Guoping, Chang, Jiang. Silicate bioceramics induce angiogenesis during bone regeneration. ACTA BIOMATERIALIA[J]. 2012, 8(1): 341-349, http://dx.doi.org/10.1016/j.actbio.2011.09.008.
[16] Lu, Hongxu, Hoshiba, Takashi, Kawazoe, Naoki, Chen, Guoping. Comparison of decellularization techniques for preparation of extracellular matrix scaffolds derived from three-dimensional cell culture. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A[J]. 2012, 100A(9): 2507-2516, https://www.webofscience.com/wos/woscc/full-record/WOS:000306922000034.
[17] Lu, Hongxu, Hoshiba, Takashi, Kawazoe, Naoki, Chen, Guoping. Autologous extracellular matrix scaffolds for tissue engineering. BIOMATERIALS[J]. 2011, 32(10): 2489-2499, http://dx.doi.org/10.1016/j.biomaterials.2010.12.016.
[18] Lu, Hongxu, Ko, YoungGwang, Kawazoe, Naoki, Chen, Guoping. Culture of bovine articular chondrocytes in funnel-like collagen-PLGA hybrid sponges. BIOMEDICAL MATERIALS[J]. 2011, 6(4): https://www.webofscience.com/wos/woscc/full-record/WOS:000292889900011.
[19] Lu, Hongxu, Hoshiba, Takashi, Kawazoe, Naoki, Koda, Ichie, Song, Minghui, Chen, Guoping. Cultured cell-derived extracellular matrix scaffolds for tissue engineering. BIOMATERIALS[J]. 2011, 32(36): 9658-9666, http://dx.doi.org/10.1016/j.biomaterials.2011.08.091.
[20] Lu, Hongxu, Ko, YoungGwang, Kawazoe, Naoki, Chen, Guoping. Cartilage tissue engineering using funnel-like collagen sponges prepared with embossing ice particulate templates. BIOMATERIALS[J]. 2010, 31(22): 5825-5835, http://dx.doi.org/10.1016/j.biomaterials.2010.04.019.
[21] 吕宏旭, 汪岷, 李红岩, 郭华荣, 张士璀, 包振民, 周丽. 利用牙鲆鳃细胞系分离和培养淋巴囊肿病毒. 青岛海洋大学学报：自然科学版[J]. 2003, 33(2): 233-239, http://lib.cqvip.com/Qikan/Article/Detail?id=7595974.