脑机接口与脑成像：开发和运用先进的神经电极、生物成像和AI算法，构建高性能生物界面，并开展基础脑科学、生物光电子诊疗、脑机融合等前瞻性研究。课题组与境内外顶尖高校、研究所、医院和企业均有合作，对外交流机会众多，除致力于前沿颠覆性技术攻关外，相关成果正在面向临床医疗和企业转化。

1. “Ultraflexible neural electrodes for long-lasting intracortical recording,” iScience 8, 101387 (2020). 
2. “Multimodal mapping of neural activity and cerebral blood flow reveals long-lasting neurovascular dissociations after small-scale strokes,” Science Advances 6, eaba1933 (2020). 
3. “Longitudinal neural and vascular recovery following ultraflexible neural electrode implantation in aged mice,” Biomaterials 291, 121905 (2022).
4. "Ultraflexible electrode arrays for months-long high-density electrophysiological mapping of thousands of neurons in rodents," Nature Biomedical Engineering 7, 520 (2023).
5. "Low-threshold, high-resolution, chronically stable intracortical microstimulation by ultraflexible electrodes," Cell Reports 42, 112554 (2023).
6. “植入式多模态神经接口前沿进展(特邀),” 中国激光 (2023).
7. “Ultraflexible Neural Electrodes enabled Synchronized Long Term Dopamine Detection and Wide Band, Chronic Recording in Deep Brain,” ACS Nano 18, 34272 (2024). 
8. “大规模神经记录的峰电位聚类算法(特邀),” 计算机工程 (2024). 
9. “Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts,” Advanced Science 12,  2417003 (2025).
10. “Temporal coding carries more stable cortical visual representations than firing rate over time,” Nature Communications 16, 7162 (2025). 
11. ““事件驱动”显微成像: 生物活体成像新前沿(特邀),” 激光与光电子学进展 (2025).
12. “Extreme manufacturing of minimally invasive intracortical neural electrodes,” International Journal of Extreme Manufacturing 8, 022009 (2026). 
13. "Ultraflexible subcellular-scale PINE arrays for month-long intracellular potassium flux monitoring in plants with nanomolar accuracy," bioRxiv 2026.01.30.702757 (2026).
14. "Full-span reversible space-time birefringence," Laser & Photonics Reviews, e03213 (2026).
15. "TF-UNet: Resolving complex speckles for single-shot reconstruction of 512×512-matrix images using a micron-sized optical fiber," Laser & Photonics Reviews, e03025 (2026).
16. “Ultra-low-illumination, high-fidelity longitudinal monitoring of cerebral perfusion via deep learning-enhanced laser speckle contrast imaging,” bioRxiv 2026.03.10.710928 (2026).

(*A full publication list can be found on Dr. Fei He's Google Scholar Profile).

每年招收1-2名具有光学、电子、计算机、生物医学工程或材料学等专业背景的研究生(含联培、留学生等)。

080300-光学工程
085400-电子信息
083100-生物医学工程

脑成像/神经光子学
脑机接口/神经工程
微纳加工/生物电子

2005-09--2010-06   中国科学院上海光机所   博士
2001-09--2005-06   浙江大学光电系   学士（双学位）

2021~现在,  中国科学院上海光机所, 课题组长、研究员
2019~2021, 美国莱斯大学 电子与计算机工程&神经工程, Research Specialist
2016~2019, 美国德州大学奥斯汀分校 生物医学工程, Research Fellow
2014~2016, 日本理化学研究所, 客座研究员
2012~2016, 中国科学院上海光机所, 副研究员
2010~2012, 中国科学院上海光机所, 助理研究员

已指导学生

聂雨涵  硕士研究生  080300-光学工程  

现指导学生

李芳媛  博士研究生  070207-光学  

余晨晖  博士研究生  080300-光学工程  

孙浩  硕士研究生  080300-光学工程  

朱冠熠  硕士研究生  085408-光电信息工程  

林慕花  硕士研究生  085408-光电信息工程