基本信息
毛莉  女  硕导  中国科学院生态环境研究中心
电子邮件: limao@rcees.ac.cn
通信地址: 北京市海淀区双清路18号环境科学楼611室
邮政编码:

招生信息

   
招生专业
083001-环境科学
083002-环境工程
招生方向
自由基反应化学,高级氧化与化学发光,巯基化合物的抗氧化与促氧化行为研究
高级氧化,污染控制化学

教育背景

2007-09--2011-06   中国科学院生态环境研究中心   环境科学/博士

工作经历

   
工作简历
2021-02~现在, 中国科学院生态环境研究中心, 副研究员
2013-07~2021-02,中国科学院生态环境研究中心, 助理研究员
2011-07~2013-06,中国科学院生态环境研究中心, 生物学/博士后
2007-09~2011-06,中国科学院生态环境研究中心, 环境科学/博士

专利与奖励

   
奖励信息
(1) 第十届全国环境化学大会环境自由基化学“青年报告奖”, 一等奖, 其他, 2019
专利成果
( 1 ) 检测卤代芳烃类有机物的方法, 2012, 第 2 作者, 专利号: CN102809559A

出版信息

   
发表论文
(1) Molecular mechanism for the unusual enhancement of the second-step chemiluminescence production from the carcinogenic tetrabromohydroquinone and H2O2., J Environ Sci, 2024, 
(2) Molecular Mechanism of Unexpected Metal-Independent Hydroxyl Radical Production by Mercaptotriazole and H2O2, Environ Sci Technol, 2024, 
(3) Molecular Mechanism of Unexpected Metal-Independent Hydroxyl Radical Production by Mercaptotriazole and H2O2, Environ Sci Technol, 2024, 
(4) Unprecedented sulfenic acid-dependent hydroxyl radical production and DNA damage by N-heterocyclic thiols and H2O2, Chem. Eng. J., 2024, 第 1 作者
(5) Molecular mechanism of the metal-independent production of hydroxyl radicals by thiourea dioxide and H2O2, Proc Natl Acad Sci USA, 2024, 第 1 作者
(6) An unprecedented free radical mechanism for the formation of DNA adducts by the carcinogenic N-sulfonated metabolite of aristolochic acids, FREE RADICAL BIOLOGY AND MEDICINE, 2023, 第 3 作者
(7) Mechanistic investigation of the differential synergistic neurotoxicity between pesticide metam sodium and copper or zinc, CHEMOSPHERE, 2023, 第 5 作者
(8) Molecular mechanism for the activation of the potent hepatotoxin acetylhydrazine: Identification of the initial N-centered radical and the secondary C-centered radical intermediates, FREE RADICAL BIOLOGY AND MEDICINE, 2023, 第 0 作者
(9) Mechanistic Investigation of H2O2-dependent Chemiluminescence from Tetrabromo-1,4-Benzoquinone, CHEMPHYSCHEM, 2022, 第 2 作者
(10) Detecting and Quantifying Polyhaloaromatic Environmental Pollutants by Chemiluminescence-Based Analytical Method, MOLECULES, 2021, 第 11 作者
(11) Mechanistic Study on Chemiluminescence of Chloranilic Acid by Co(II)-Mediated Fenton-like System, JOURNAL OF ORGANIC CHEMISTRY, 2021, 第 2 作者
(12) The cell-impermeable Ru(II) polypyridyl complex as a potent intracellular photosensitizer under visible light irradiation via ion-pairing with suitable lipophilic counter-anions, FREE RADICAL BIOLOGY AND MEDICINE, 2021, 第 8 作者
(13) Structure-Activity Relationship Investigation on Reaction Mechanism between Chlorinated Quinoid Carcinogens and Clinically-Used Aldoxime Nerve-Agent Antidote under Physiological Condition, CHEMICAL RESEARCH IN TOXICOLOGY, 2021, 第 10 作者
(14) Caffeic Acid Phenyl Ester (CAPE) Protects against Iron-Mediated Cellular DNA Damage through Its Strong Iron-Binding Ability and High Lipophilicity, ANTIOXIDANTS, 2021, 第 11 作者
(15) The critical role of superoxide anion radicals on delaying tetrachlorohydroquinone autooxidation by penicillamine, FREE RADICAL BIOLOGY AND MEDICINE, 2021, 第 1 作者
(16) First Direct and Unequivocal Electron Spin Resonance Spin-Trapping Evidence for pH-Dependent Production of Hydroxyl Radicals from Sulfate Radicals, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 第 3 作者
(17) An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids, FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 6 作者
(18) Chiral Os(II) Polypyridyl Complexes as Enantioselective Nuclear DNA Imaging Agents Especially Suitable for Correlative High-Resolution Light and Electron Microscopy Studies, ACS APPLIED MATERIALS & INTERFACES, 2020, 第 4 作者
(19) An unexpected antioxidant and redox activity for the classic copper-chelating drug penicillamine, FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 1 作者
(20) Unprecedented strong intrinsic chemiluminescence generation from degradation of halogenated hydroxy-quinoid pollutants by Co(II)-mediated advanced oxidation processes: The critical role of site-specific production of hydroxyl radicals, CHEMICAL ENGINEERING JOURNAL, 2020, 第 1 作者
(21) First unequivocal identification of the critical acyl radicals from the anti-tuberculosis drug isoniazid and its hydrazide analogs by complementary applications of ESR spin-trapping and HPLC/MS methods, FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 3 作者
(22) Molecular mechanisms and potential applications of the intrinsic chemiluminescence produced from the degradation of haloaromatic pollutants during environmentally-friendly advanced oxidation processes, ENVIRONMENTAL SCIENCE-WATER RESEARCH & TECHNOLOGY, 2020, 第 1 作者
(23) Corrigendum to "An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids" Free Radic. Biol. Med. 146 (2020) 150���159/FRBM_2019_405, FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 5 作者
(24) An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids (vol 146, pg 150, 2020), FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 5 作者
(25) Unexpected activation of N-alkyl hydroxamic acids to produce reactive N-centered free radicals and DNA damage by carcinogenic chlorinated quinones under normal physiological conditions, FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 8 作者
(26) Mechanism of synergistic DNA damage induced by caffeic acid phenethyl ester (CAPE) and Cu(II): Competitive binding between CAPE and DNA with Cu(II)/Cu(I), FREE RADICAL BIOLOGY AND MEDICINE, 2020, 第 2 作者
(27) Mechanism of unprecedented hydroxyl radical production and site-specific oxidative DNA damage by photoactivation of the classic arylhydroxamic acid carcinogens, CARCINOGENESIS, 2019, 第 5 作者
(28) Molecular mechanism for the activation of the anti-tuberculosis drug isoniazid by Mn(III): First detection and unequivocal identification of the critical N-centered isoniazidyl radical and its exact location, FREE RADICAL BIOLOGY AND MEDICINE, 2019, 第 6 作者
(29) Intrinsic chemiluminescence production from the degradation of haloaromatic pollutants during environmentally-friendly advanced oxidation processes: mechanism, structure-activity relationship and potential applications, JOURNAL OF ENVIRONMENTAL SCIENCES, 2017, 第 11 作者
(30) Mechanism of intrinsic chemiluminescence production from the degradation of persistent chlorinated phenols by the fenton system: a structure-activity relationship study and the critical role of quinoid and semiquinone radical intermediates, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 第 2 作者
(31) Chemiluminescence generation from haloaromatic pollutants: structure-activity relationship, molecular mechanism and potential applications, PROGRESS IN CHEMISTRY, 2017, 第 11 作者
(32) Why Does 2,3,5,6-Tetrachlorophenol Generate the Strongest Intrinsic Chemiluminescence among All Nineteen Chlorophenolic Persistent Organic Pollutants during Environmentally-friendly Advanced Oxidation Process?, SCIENTIFIC REPORTS, 2016, 第 2 作者
(33) Intrinsic Chemiluminescence Generation during Advanced Oxidation of Persistent Halogenated Aromatic Carcinogens, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2015, 第 1 作者
(34) Unprecedented hydroxyl radical-dependent two-step chemiluminescence production by polyhalogenated quinoid carcinogens and H2O2, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 第 2 作者
(35) TEMPORARY REMOVAL: An unexpected new pathway for nitroxide radical production via more reactve nitrogen-centered amidyl radical intermediate during detoxification of the carcinogenic halogenated quinones by N-alkyl hydroxamic acids, FREE RADICAL BIOLOGY AND MEDICINE, 第 5 作者

科研活动

   
科研项目
( 1 ) 硫脲类化合物介导产生羟基/有机自由基的分子机制及结构-效应关系 研究, 负责人, 国家任务, 2024-01--2027-12
( 2 ) 典型巯基化合物产生活性羟基自由基的新型分子机制及生物学效应, 负责人, 国家任务, 2022-01--2025-12
( 3 ) 钴-类Fenton体系导致卤代醌类化合物产生独特化学发光的分子机制及应用研究, 负责人, 国家任务, 2016-01--2019-12
( 4 ) 一类新型的依赖于羟基自由基化学发光体系的研究, 负责人, 国家任务, 2013-01--2015-12