基本信息

徐大威 男 硕导 国家纳米科学中心
电子邮件: xudw@nanoctr.cn
通信地址: 海淀区中关村北一条11号
邮政编码:
电子邮件: xudw@nanoctr.cn
通信地址: 海淀区中关村北一条11号
邮政编码:
招生信息
招生专业
0703Z1-化学生物学
0703J1-纳米科学与技术
0703Z2-生物无机化学
0703J1-纳米科学与技术
0703Z2-生物无机化学
招生方向
合成生物学
蛋白及多肽设计
蛋白及多肽设计
工作经历
工作简历
2013-08~2017-12,美国克拉克森大学, 博士
出版信息
发表论文
(1) Natural Wood���Derived Macroporous Cellulose for Highly Efficient and Ultrafast Elimination of Double���Stranded RNA from In Vitro���Transcribed mRNA, Advanced Materials, 2023, 第 9 作者 通讯作者
(2) Lateral flow immunoassay for rapid and sensitive detection of dsRNA contaminants in in vitro-transcribed mRNA products, Molecular Therapy-Nucleic Acids, 2023, 第 8 作者 通讯作者
(3) Filamentous chaperone protein-based hydrogel stabilizes enzymes against thermal inactivation, CHEMICAL COMMUNICATIONS, 2021, 第 1 作者
(4) Structural Determination of a Filamentous Chaperone to Fabricate Electronically Conductive Metalloprotein Nanowires, ACS NANO, 2020, 第 4 作者
(5) CRISPR/Cas-directed programmable assembly of multi-enzyme complexes, CHEMICAL COMMUNICATIONS, 2020, 第 4 作者
(6) Shaping the Future of Protein Engineering, BIOCHEMISTRY, 2019, 第 2 作者
(7) Assembly of Multicomponent Protein Filaments Using Engineered Subunit Interfaces, ACS SYNTHETIC BIOLOGY, 2018, 第 3 作者
(8) Fabrication and Microscopic and Spectroscopic Characterization of Cytocompatible Self-Assembling Antimicrobial Nanofibers, ACS INFECTIOUS DISEASES, 2018, 第 1 作者
(9) Design and fabrication of reduction-sensitive cell penetrating nanofibers for enhanced drug efficacy, JOURNAL OF MATERIALS CHEMISTRY B, 2018, 第 2 作者
(10) Fabrication of self-assembling nanofibers with optimal cell uptake and therapeutic delivery efficacy, Fabrication of self-assembling nanofibers with optimal cell uptake and therapeutic delivery efficacy, BIOACTIVE MATERIALS, 2017, 第 1 作者
(11) Toward Hemocompatible Self-assembling Antimicrobial Nanofibers: Understanding the Synergistic Effect of Supramolecular Structure and PEGylation on Hemocompatibility, RSC ADVANCES, 2016, 第 1 作者
(12) Biosensors based on modularly designed synthetic peptides for recognition, detection and live/dead differentiation of pathogenic bacteria, BIOSENSORS AND BIOELECTRONICS, 2016, 第 3 作者
(13) Distinct Membrane Disruption Pathways Are Induced by 40-Residue ��-Amyloid Peptides *, THE JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 第 5 作者
(14) Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity, CHEMICAL COMMUNICATIONS, 2015, 第 1 作者
(15) Designed filamentous cell penetrating peptides: probing supramolecular structure-dependent membrane activity and transfection efficiency, CHEMICAL COMMUNICATIONS, 2015, 第 1 作者
(16) Self-assembly of cationic multidomain peptide hydrogels: supramolecular nanostructure and rheological properties dictate antimicrobial activity ���, NANOSCALE, 2015, 第 2 作者
(17) Surface modification of titanium substrates with silver nanoparticles embedded sulfhydrylated chitosan/gelatin polyelectrolyte multilayer films for antibacterial application, JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2014, 第 2 作者
(18) Effects of titanium nanoparticles on adhesion, migration, proliferation, and differentiation of mesenchymal stem cells, INTERNATIONAL JOURNAL OF NANOMEDICINE, 2013,
(19) Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses, COLLOIDS AND SURFACES B-BIOINTERFACES, 2013, 第 1 作者
(20) TiO2 nanotubes as drug nanoreservoirs for the regulation of mobility and differentiation of mesenchymal stem cells, ACTA BIOMATERIALIA, 2012, 第 4 作者
(21) Cell-Specific Intracellular Anticancer Drug Delivery from Mesoporous Silica Nanoparticles with pH Sensitivity, ADVANCED HEALTHCARE MATERIALS, 2012, 第 5 作者
(22) Redox-Responsive Molecular Nanoreservoirs for Controlled Intracellular Anticancer Drug Delivery Based on Magnetic Nanoparticles, ADVANCED MATERIALS, 2012, 第 7 作者
(2) Lateral flow immunoassay for rapid and sensitive detection of dsRNA contaminants in in vitro-transcribed mRNA products, Molecular Therapy-Nucleic Acids, 2023, 第 8 作者 通讯作者
(3) Filamentous chaperone protein-based hydrogel stabilizes enzymes against thermal inactivation, CHEMICAL COMMUNICATIONS, 2021, 第 1 作者
(4) Structural Determination of a Filamentous Chaperone to Fabricate Electronically Conductive Metalloprotein Nanowires, ACS NANO, 2020, 第 4 作者
(5) CRISPR/Cas-directed programmable assembly of multi-enzyme complexes, CHEMICAL COMMUNICATIONS, 2020, 第 4 作者
(6) Shaping the Future of Protein Engineering, BIOCHEMISTRY, 2019, 第 2 作者
(7) Assembly of Multicomponent Protein Filaments Using Engineered Subunit Interfaces, ACS SYNTHETIC BIOLOGY, 2018, 第 3 作者
(8) Fabrication and Microscopic and Spectroscopic Characterization of Cytocompatible Self-Assembling Antimicrobial Nanofibers, ACS INFECTIOUS DISEASES, 2018, 第 1 作者
(9) Design and fabrication of reduction-sensitive cell penetrating nanofibers for enhanced drug efficacy, JOURNAL OF MATERIALS CHEMISTRY B, 2018, 第 2 作者
(10) Fabrication of self-assembling nanofibers with optimal cell uptake and therapeutic delivery efficacy, Fabrication of self-assembling nanofibers with optimal cell uptake and therapeutic delivery efficacy, BIOACTIVE MATERIALS, 2017, 第 1 作者
(11) Toward Hemocompatible Self-assembling Antimicrobial Nanofibers: Understanding the Synergistic Effect of Supramolecular Structure and PEGylation on Hemocompatibility, RSC ADVANCES, 2016, 第 1 作者
(12) Biosensors based on modularly designed synthetic peptides for recognition, detection and live/dead differentiation of pathogenic bacteria, BIOSENSORS AND BIOELECTRONICS, 2016, 第 3 作者
(13) Distinct Membrane Disruption Pathways Are Induced by 40-Residue ��-Amyloid Peptides *, THE JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 第 5 作者
(14) Designed supramolecular filamentous peptides: balance of nanostructure, cytotoxicity and antimicrobial activity, CHEMICAL COMMUNICATIONS, 2015, 第 1 作者
(15) Designed filamentous cell penetrating peptides: probing supramolecular structure-dependent membrane activity and transfection efficiency, CHEMICAL COMMUNICATIONS, 2015, 第 1 作者
(16) Self-assembly of cationic multidomain peptide hydrogels: supramolecular nanostructure and rheological properties dictate antimicrobial activity ���, NANOSCALE, 2015, 第 2 作者
(17) Surface modification of titanium substrates with silver nanoparticles embedded sulfhydrylated chitosan/gelatin polyelectrolyte multilayer films for antibacterial application, JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2014, 第 2 作者
(18) Effects of titanium nanoparticles on adhesion, migration, proliferation, and differentiation of mesenchymal stem cells, INTERNATIONAL JOURNAL OF NANOMEDICINE, 2013,
(19) Surface functionalization of titanium substrates with cecropin B to improve their cytocompatibility and reduce inflammation responses, COLLOIDS AND SURFACES B-BIOINTERFACES, 2013, 第 1 作者
(20) TiO2 nanotubes as drug nanoreservoirs for the regulation of mobility and differentiation of mesenchymal stem cells, ACTA BIOMATERIALIA, 2012, 第 4 作者
(21) Cell-Specific Intracellular Anticancer Drug Delivery from Mesoporous Silica Nanoparticles with pH Sensitivity, ADVANCED HEALTHCARE MATERIALS, 2012, 第 5 作者
(22) Redox-Responsive Molecular Nanoreservoirs for Controlled Intracellular Anticancer Drug Delivery Based on Magnetic Nanoparticles, ADVANCED MATERIALS, 2012, 第 7 作者
科研活动
科研项目
( 1 ) 纳米材料诱发机体免疫互作与应答机制研究, 参与, 国家任务, 2023-05--2028-04