基本信息
Goran Angelovski  男  博导  中国科学院脑科学与智能技术卓越创新中心
email: goran.angelovski@icpbr.ac.cn
address: 上海市强业路500号5号楼
postalCode:

招生信息

   
招生专业
071006-神经生物学
071009-细胞生物学
招生方向
分子功能性磁共振神经成像技术的应用
生物响应造影剂开发

教育背景

2000-10--2004-06   University of Dortmund   博士

工作经历

   
工作简历
2020-09~现在, 中国科学院脑科学与智能技术卓越创新中心, 高级研究员
2007-01~2020-09,MPI for Biological Cybernetics, 项目组长,研究组长
2005-03~2007-01,MPI for Biological Cybernetics, 博士后
2000-10~2004-06,University of Dortmund, 博士

出版信息

   
发表论文
(1) Opportunities and challenges with hyperpolarized bioresponsive probes for functional imaging using magnetic resonance, Nature Chemistry, 2023, 通讯作者
(2) How to Develop Bioresponsive MRI Probes Based on Paramagnetic Gd(III) for in vivo Applications, Analysis & Sensing, 2023, 通讯作者
(3) Stable and inert macrocyclic cobalt(II) and nickel(II) complexes with paraCEST response, DALTON TRANSACTIONS, 2022, 
(4) In Situ Ternary Adduct Formation of Yttrium Polyaminocarboxylates Leads to Small Molecule Capture and Activation, CHEMISTRY-A EUROPEAN JOURNAL, 2022, 
(5) Insights into the Responding Modes of Highly Potent Gadolinium-Based Magnetic Resonance Imaging Probes Sensitive to Zinc Ions, INORGANIC CHEMISTRY, 2022, 
(6) Paramagnetic chemical exchange saturation transfer agents and their perspectives for application in magnetic resonance imaging, INTERNATIONAL REVIEWS IN PHYSICAL CHEMISTRY, 2021, 
(7) Highly Potent MRI Contrast Agent Displaying Outstanding Sensitivity to Zinc Ions, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 
(8) Lanthanide(III) Complexes Based on an 18-Membered Macrocycle Containing Acetamide Pendants. Structural Characterization and paraCEST Properties, INORGANIC CHEMISTRY, 2021, 
(9) Exploring the hyperpolarisation of EGTA-based ligands using SABRE, DALTONTRANSACTIONS, 2021, 
(10) The effects of nitroxide structure upon H-1 Overhauser dynamic nuclear polarization efficacy at ultralow-field, JOURNAL OF CHEMICAL PHYSICS, 2021, 
(11) RGD-Peptide Functionalization Affects the In Vivo Diffusion of a Responsive Trimeric MRI Contrast Agent through Interactions with Integrins, JOURNAL OF MEDICINAL CHEMISTRY, 2021, 
(12) Dendrimeric calcium-sensitive MRI probes: the first low-field relaxometric study, JOURNAL OF MATERIALS CHEMISTRY B, 2020, 
(13) Human Serum Albumin Labelled with Sterically-Hindered Nitroxides as Potential MRI Contrast Agents, MOLECULES, 2020, 
(14) Unexpected Trends in the Stability and Dissociation Kinetics of Lanthanide(III) Complexes with Cyclen-Based Ligands across the Lanthanide Series, INORGANICCHEMISTRY, 2020, 
(15) A ratiometric 19F MR-based method for the quantification of Ca2+ using responsive paramagnetic probes., Chem. Commun., 2020, 通讯作者
(16) Macrocyclic Chelates Bridged by a Diaza-Crown Ether: Towards Multinuclear Bimodal Molecular Imaging Probes, MOLECULES, 2020, 
(17) Combination of bioresponsive chelates and perfluorinated lipid nanoparticles enables in vivo MRI probe quantification, CHEMICAL COMMUNICATIONS, 2020, 
(18) The use of yttrium in medical imaging and therapy: historical background and future perspectives, CHEMICAL SOCIETY REVIEWS, 2020, 
(19) Europium(III) Macrocyclic Chelates Appended with Tyrosine-based Chromophores and Di-(2-picolyl)amine-based Receptors: Turn-On Luminescent Chemosensors Selective to Zinc(II) Ions, CHEMPLUSCHEM, 2020, 
(20) Inert macrocyclic Eu3+ complex with affirmative paraCEST features, INORGANIC CHEMISTRY FRONTIERS, 2020, 
(21) Solid phase synthesis in the development of magnetic resonance imaging probes, ORGANIC CHEMISTRY FRONTIERS, 2020, 
(22) Reinforced Ni(II)-cyclam derivatives as dual 1H/19F MRI probes., Chem. Commun., 2019, 第 1 作者
(23) Toward MRI and Optical Detection of Zwitterionic Neurotransmitters: Near-Infrared Luminescent and Magnetic Properties of Macrocyclic Lanthanide(III) Complexes Appended with a Crown Ether and a Benzophenone Chromophore, INORGANIC CHEMISTRY, 2019, 
(24) In-depth Study of a Novel Class of Ditopic Gadolinium(III)-based MRI Probes Sensitive to Zwitterionic Neurotransmitters, Front. Chem., 2019, 通讯作者
(25) In-depth Study of a Novel Class of Ditopic Gadolinium(III)-based MRI Probes Sensitive to Zwitterionic Neurotransmitters, FRONTIERS IN CHEMISTRY, 2019, 
(26) Translating a Low-Molecular-Weight MRI Probe Sensitive to Amino Acid Neurotransmitters into a PAMAM Dendrimer Conjugate: The Impact of Conjugation, CHEMNANOMAT, 2019, 
(27) Water soluble Eu(III) complexes of macrocyclic triamide ligands: Structure, stability, luminescence and redox properties, INORGANICA CHIMICA ACTA, 2019, 
(28) A low-molecular-weight ditopic MRI probe for ratiometric sensing of zwitterionic amino acid neurotransmitters, CHEMICAL COMMUNICATIONS, 2019, 
(29) Solid-Phase-Supported Approach for the Preparationof Bioresponsive and Multifunctional MRI Probes, ORGANIC LETTERS, 2019, 
(30) Lanthanide Complexes with 1H paraCEST and 19F Response for Magnetic Resonance Imaging Applications., Inorg. Chem., 2019, 第 1 作者
(31) Early detection and monitoring of cerebral ischemia using calcium-responsive MRI probes, PROCEEDINGSOFTHENATIONALACADEMYOFSCIENCESOFTHEUNITEDSTATESOFAMERICA, 2019, 
(32) Investigations into the effects of linker length elongation on the behaviour of calcium-responsive MRI probes, DALTON TRANSACTIONS, 2019, 
(33) Gadolinium(III)‐Based Dual 1H/19F Magnetic Resonance Imaging Probes., Chem. Eur. J., 2019, 通讯作者

科研活动

   
科研项目
( 1 ) 功能性磁共振成像应用中多聚金属离子响应纳米探针的开发, 负责人, 国家任务, 2022-01--2025-12
( 2 ) Functional Molecular Imaging of Neuronal Activity with Bioresponsive MRI Probes, 负责人, 国家任务, 2023-01--2024-12