基本信息
陈联国  男  博导  中国科学院水生生物研究所
电子邮件: lchenam@ihb.ac.cn
通信地址: 湖北省武汉市武昌区东湖南路7号中科院水生所
邮政编码:

招生信息

   
招生专业
071004-水生生物学
090801-水产养殖
招生方向
环境有机污染物,生态毒理学,水生生物,毒性机理,污染物环境行为

专利与奖励

   
奖励信息
(1) 中科院武汉分院优秀研究生导师奖, 院级, 2021
(2) 国家青年海外人才计划, 国家级, 2020
(3) 武汉市黄鹤英才, 市地级, 2020
(4) 武汉市青年科技朝阳计划, 市地级, 2020
(5) 教育部自然科学二等奖, 二等奖, 部委级, 2019
(6) 湖北省青年****, 省级, 2019
(7) 湖北省青年科技晨光计划, 省级, 2019
专利成果
( 1 ) 一种Pull-down鉴定污染物分子靶点的方法, 2019, 第 1 作者, 专利号: CN110045128A

出版信息

   
发表论文
(1) In vitro biolayer interferometry analysis of acetylcholinesterase as a potential target of aryl-organophosphorus flame-retardants, JOURNAL OF HAZARDOUS MATERIALS, 2021, 第 6 作者
(2) Nonalcoholic Fatty Liver Disease Development in Zebrafish upon Exposure to Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate, a Novel Brominated Flame Retardant, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2021, 第 8 作者
(3) Interaction between probiotic additive and perfluorobutanesulfonate pollutant on offspring growth and health after parental exposure using zebrafish, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 通讯作者
(4) Shift in skin microbiota and immune functions of zebrafish after combined exposure to perfluorobutanesulfonate and probiotic Lactobacillus rhamnosus, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 通讯作者
(5) Disturbances in Microbial and Metabolic Communication across the Gut-Liver Axis Induced by a Dioxin-like Pollutant: An Integrated Metagenomics and Metabolomics Analysis, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2021, 通讯作者
(6) Visual system: An understudied target of aquatic toxicology, AQUATIC TOXICOLOGY, 2020, 通讯作者
(7) Dietary administration of probiotic Lactobacillus rhamnosus modulates the neurological toxicities of perfluorobutanesulfonate in zebrafish, ENVIRONMENTAL POLLUTION, 2020, 通讯作者
(8) Early-life exposure to the organophosphorus flame-retardant tris (1,3-dichloro-2-propyl) phosphate induces delayed neurotoxicity associated with DNA methylation in adult zebrafish, ENVIRONMENT INTERNATIONAL, 2020, 第 7 作者
(9) Unexpected Observations: Probiotic Administration Greatly Aggravates the Reproductive Toxicity of Perfluorobutanesulfonate in Zebrafish, CHEMICAL RESEARCH IN TOXICOLOGY, 2020, 通讯作者
(10) Parental exposure to perfluorobutane sulfonate disturbs the transfer of maternal transcripts and offspring embryonic development in zebrafish, CHEMOSPHERE, 2020, 通讯作者
(11) Probiotic modulation of perfluorobutanesulfonate toxicity in zebrafish: Disturbances in retinoid metabolism and visual physiology, CHEMOSPHERE, 2020, 通讯作者
(12) Binary exposure to hypoxia and perfluorobutane sulfonate disturbs sensory perception and chromatin topography in marine medaka embryos, ENVIRONMENTAL POLLUTION, 2020, 通讯作者
(13) Interaction between hypoxia and perfluorobutane sulfonate on developmental toxicity and endocrine disruption in marine medaka embryos, AQUATIC TOXICOLOGY, 2020, 通讯作者
(14) Probiotic Modulation of Lipid Metabolism Disorders Caused by Perfluorobutanesulfonate Pollution in Zebrafish, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2020, 通讯作者
(15) Optical toxicity of triphenyl phosphate in zebrafish larvae, AQUATIC TOXICOLOGY, 2019, 第 3 作者
(16) Perfluorobutanesulfonate Exposure Skews Sex Ratio in Fish and Transgenerationally Impairs Reproduction, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2019, 通讯作者
(17) Acute exposure to triphenyl phosphate (TPhP) disturbs ocular development and muscular organization in zebrafish larvae, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 通讯作者
(18) Organic ultraviolet (UV) filters in the South China sea coastal region: Environmental occurrence, toxicological effects and risk assessment, ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2019, 第 2 作者
(19) Activation of aryl hydrocarbon receptor by dioxin directly shifts gut microbiota in zebrafish, ENVIRONMENTAL POLLUTION, 2019, 通讯作者
(20) Parental co-exposure to bisphenol A and nano-TiO2 causes thyroid endocrine disruption and developmental neurotoxicity in zebrafish offspring, SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 第 2 作者
(21) Contamination by perfluoroalkyl substances and microbial community structure in Pearl River Delta sediments, ENVIRONMENTAL POLLUTION, 2019, 通讯作者
(22) Variation in microbial community structure in surface seawater from Pearl River Delta: Discerning the influencing factors, SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 通讯作者
(23) Parental Exposure to Perfluorobutanesulfonate Impairs Offspring Development through Inheritance of Paternal Methylome, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2019, 通讯作者
(24) TiO2 nanoparticles and BPA are combined to impair the development of offspring zebrafish after parental coexposure, CHEMOSPHERE, 2019, 通讯作者
(25) Bioconcentration, Biotransformation, and Thyroid Endocrine Disruption of Decabromodiphenyl Ethane (Dbdpe), A Novel Brominated Flame Retardant, in Zebrafish Larvae, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2019, 第 5 作者
(26) Perfluorobutanesulfonate Exposure Causes Durable and Transgenerational Dysbiosis of Gut Microbiota in Marine Medaka, ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2018, 通讯作者
(27) Multigenerational Disruption of the Thyroid Endocrine System in Marine Medaka after a Life-Cycle Exposure to Perfluorobutanesulfonate, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2018, 第 1 作者
(28) Dysregulation of Intestinal Health by Environmental Pollutants: Involvement of the Estrogen Receptor and Aryl Hydrocarbon Receptor, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2018, 第 1 作者
(29) Accumulation of perfluorobutane sulfonate (PFBS) and impairment of visual function in the eyes of marine medaka after a life-cycle exposure, AQUATIC TOXICOLOGY, 2018, 第 1 作者
(30) Sea Nine 211 as antifouling biocide: A coastal pollutant of emerging concern, Sea Nine 211 as antifouling biocide: A coastal pollutant of emerging concern, 环境科学学报:英文版, 2017, 第 1 作者
(31) SeaNine 211 as antifouling biocide: A coastal pollutant of emerging concern, JOURNAL OF ENVIRONMENTAL SCIENCES, 2017, 通讯作者
(32) Linking genomic responses of gonads with reproductive impairment in marine medaka (Oryzias melastigma) exposed chronically to the chemopreventive and antifouling agent, 3,3'-diindolylmethane (DIM), AQUATIC TOXICOLOGY, 2017, 
(33) Identification of Molecular Targets for 4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) in Teleosts: New Insight into Mechanism of Toxicity, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 第 1 作者
(34) Optimization of antifouling coatings incorporating butenolide, a potent antifouling agent via field and laboratory tests, PROGRESS IN ORGANIC COATINGS, 2017, 第 1 作者
(35) Endocrine disruption throughout the hypothalamus-pituitary-gonadal-liver (hpgl) axis in marine medaka (oryzias melastigma) chronically exposed to the antifouling and chemopreventive agent, 3,3 '-diindolylmethane (dim), CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 第 1 作者
(36) Chronic Exposure of Marine Medaka (Oryzias melastigma) to 4,5-Dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT) Reveals Its Mechanism of Action in Endocrine Disruption via the Hypothalamus-Pituitary-Gonadal-Liver (HPGL) Axis, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016, 第 1 作者
(37) High-throughput transcriptome sequencing of the cold seep mussel Bathymodiolus platifrons, SCIENTIFIC REPORTS, 2015, 第 4 作者
(38) Proteomic changes in brain tissues of marine medaka (Oryzias melastigma) after chronic exposure to two antifouling compounds: Butenolide and 4,5-dichloro-2-n-octyl-4-isothiazolin-3-one (DCOIT), Aquatic Toxicology, 2014, 第 1 作者
(39) Effects of acute exposure to polybrominated diphenyl ethers on retinoid signaling in zebrafish larvae, ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2013, 通讯作者
(40) 多溴联苯醚(PBDEs)对斑马鱼胚胎的神经发育毒性研究, 2012, 第 1 作者
(41) Prenatal Transfer of Polybrominated Diphenyl Ethers (PBDEs) Results in Developmental Neurotoxicity in Zebrafish Larvae, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2012, 第 1 作者
(42) Alterations in retinoid status after long-term exposure to PBDEs in zebrafish (Danio rerio), AQUATIC TOXICOLOGY, 2012, 第 1 作者

科研活动

   
科研项目
( 1 ) 中科院“****”引进人才科研启动经费, 负责人, 研究所自选, 2018-09--2023-08
( 2 ) 缺氧环境下全氟丁烷磺酸盐的毒性效应与机理, 负责人, 其他任务, 2019-03--2021-03
( 3 ) 典型抗污损污染物DCOIT的内分泌干扰效应和繁殖毒性机制, 负责人, 国家任务, 2020-01--2023-12
( 4 ) 益生菌Lactobacillus rhamnosus添加剂抑制全氟丁烷磺酸污染物(PFBS)健康危害的效能研究, 负责人, 研究所自选, 2020-01--2021-12
( 5 ) 益生菌Lactobacillus rhamnosus对全氟丁烷磺酸盐(PFBS)脂质代谢毒性的调节能力和分子机制, 负责人, 国家任务, 2021-01--2023-12
( 6 ) 湖北省杰出青年基金, 负责人, 地方任务, 2021-10--2024-09
( 7 ) 国家青年海外人才计划科研经费, 负责人, 国家任务, 2021-06--2026-12