100800-中药学

天然药物化学

2008-07--2012-07   中国科学院成都生物研究所   理学博士
2005-07--2008-07   中国科学院西北高原生物研究所   理学硕士
2001-09--2005-07   淮北煤炭师范大学   学士学位

   

2023-05~现在, 中国科学院西北高原生物研究所, 研究员
2015-10~2023-05,中国科学院西北高原生物研究所, 副研究员
2015-03~2016-03,德国马克斯普朗克煤炭研究所, 访问学者
2012-07~2015-10,中国科学院西北高原生物研究所, 助理研究员
2008-07~2012-07,中国科学院成都生物研究所, 理学博士
2005-07~2008-07,中国科学院西北高原生物研究所, 理学硕士
2001-09~2005-07,淮北煤炭师范大学, 学士学位

   

（1） 青海省首届青年科技奖状, 一等奖, 省级, 2020

（ 1 ） 一种白檀提取物在制备降低血糖的食品、药品或保健品中的应用, 2022, 第 1 作者, 专利号: N.102020000016591

（ 2 ） 大花红景天提取物在制备抑制淀粉酶和葡萄糖苷酶活性的食品、药品或保健, 2022, 第 1 作者, 专利号: 2022/01098

   

（1） Characterization of alkaloids and phenolics in Nitraria roborowskii Kom. fruit by UHPLC-triple-TOF-MS/MS and its sucrase and maltase inhibitory effects, Food Chemistry, 2024, 第 12 作者  通讯作者
（2） Hypoglycemic e���ect of Nitraria tangutorum fruit by inhibiting glycosidase and regulating IRS1/PI3K/ AKT signalling pathway and its active ingredient identi���cation by UPLC-MS, Food & Function, 2023, 第 9 作者  通讯作者
（3） Hypoglycemic activity of Codonopsis pilosula (Franch.) Nannf. in vitro and in vivo and its chemical composition identification by UPLC-Triple-TOF-MS/MS, FOOD & FUNCTION, 2022, 第 6 作者  通讯作者
（4） Hypoglycemic ingredients identification of Rheum tanguticum Maxim. ex Balf. by UHPLC-triple-TOF-MS/MS and interrelationships between ingredients content and glycosidase inhibitory activities, Industrial Crops & Products, 2022, 第 1 作者  通讯作者
（5） Hypoglycemic effects of Rhodiola crenulata (HK. f. et. Thoms) H. Ohba in vitro and in vivo and its ingredient identification by UPLC-triple- TOF/MS, Food & Function, 2022, 第 1 作者  通讯作者
（6） Alkaloids and phenolics identification in fruit of Nitraria tangutorum Bobr. by UPLC-Q-TOF-MS/MS and their a-glucosidase inhibitory effects in vivo and in vitro, FOOD CHEMISTRY, 2021, 第 7 作者  通讯作者
（7） A new flavonol acylglycoside from the fruits of Nitraria tangutorum Bobr, NATURAL PRODUCT RESEARCH, 2021, 第 7 作者  通讯作者
（8） Anti-rheumatoid arthritis effects of iridoid glucosides from Lamiophlomis rotata (Benth.) kudo on adjuvant-induced arthritis in rats by OPG/RANKL/NF-��B signaling pathways, JOURNAL OF ETHNOPHARMACOLOGY, 2021, 第 8 作者
（9） Identification of phenolic compounds in fruits of Ribes stenocarpum Maxim. By UHPLC-QTOF/MS and their hypoglycemic effects in vitro and in vivo, FOOD CHEMISTRY, 2021, 第 9 作者  通讯作者
（10） Visible-light-promoted acridine red catalyzed aerobic oxidative decarboxylative acylation of ��-oxo-carboxylic acids with quinoxalin-2(1H)- ones, ORGANIC CHEMISTRY, 2020, 第 1 作者  通讯作者
（11） Variation of anthocyanin content in fruits of wild and cultivated Lycium ruthenicum, INDUSTRIAL CROPS AND PRODUCTS, 2020, 第 7 作者  通讯作者
（12） Ultrasonic extraction of anthocyanins from Lycium ruthenicum Murr. and its antioxidant activity, FOOD SCIENCE & NUTRITION, 2020, 第 7 作者  通讯作者
（13） Resveratroloside Alleviates Postprandial Hyperglycemia in Diabetic Mice by Competitively Inhibiting a-Glucosidase, J. Agric. Food Chem., 2019, 
（14） Visible-light-mediated metal-free decarboxylative acylations of isocyanides with alpha-oxocarboxylic acids and water leading to alpha-ketoamides, GREEN CHEMISTRY, 2019, 第 3 作者  通讯作者
（15） Selective assembly of N1-and N2-alkylated 1,2,3-triazoles via copper-catalyzed decarboxylative cycloaddition of alkynyl carboxylic acids with ethers and azidotrimethylsilane, ORGANIC CHEMISTRY FRONTIERS, 2019, 第 4 作者  通讯作者
（16） Direct synthesis of ��-ketophosphine oxides via copper-catalyzed difunctionalization of alkenes with H-phosphine oxides and dioxygen, TETRAHEDRON LETTERS, 2018, 第 2 作者
（17） Antioxidants from Pedicularis longiflora var. tubiformis (Klotzsch) P. C. Tsoong, RECORDS OF NATURAL PRODUCTS, 2018, 
（18） Visible-Light-Enabled Construction of Thiocarbamates from Isocyanides, Thiols, and Water at Room Temperature, ORGANIC LETTERS, 2018, 第 3 作者  通讯作者
（19） Visible-light-enabled oxyazidation of alkenes leading to alpha-azidoketones in air, GREEN CHEMISTRY, 2018, 第 3 作者  通讯作者
（20） Visible-Light-Promoted Difunctionalization of Olefins Leading to -Thiocyanato Ketones, SYNLETT, 2018, 第 2 作者  通讯作者
（21） Fatty Acid and Phytosterol Composition, and Biological Activities of Lycium ruthenicum Murr. Seed Oil, JOURNAL OF FOOD SCIENCE, 2018, 第 10 作者  通讯作者
（22） Metal-free Oxidative Coupling of Aromatic Alkenes with Thiols Leading to (E)-Vinyl Sulfones, JOURNAL OF ORGANIC CHEMISTRY, 2017, 第 2 作者
（23） Highly efficient TfOH-catalyzed head-to-tail dimerization of vinylarenes, SYNTHETIC COMMUNICATIONS, 2016, 第 1 作者
（24） Fe3O4 Nanoparticles with Ursolic Methyl Ester Induce Apoptosis of Multidrug-Resistant Leukemia KA Cell: In Vitro Evaluation, JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2016, 第 1 作者
（25） Acid-Catalyzed Oxidative Addition of Thiols to Olefins and Alkynes for a One-Pot Entry to Sulfoxides, SYNLETT, 2016, 第 1 作者
（26） SEMI-PREPARATIVE SEPARATION AND PURIFICATION OF THREE FLAVONOIDS FROM PEDICULARIS LONGIFLORA VAR. TUBIFORMIS (KLOTZSCH) P. C. TSOONG BY HSCCC, JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES, 2013, 第 5 作者  通讯作者
（27） Separation and purification of five phenylpropanoid glycosides from Lamiophlomis rotata (Benth.) Kudo by a macroporous resin column combined with high���speed counter���current chromatography, JOURNAL OF SEPARATION SCIENCE, 2013, 第 1 作者
（28） Separation and purification of water-soluble iridoid glucosides by high speed counter-current chromatography combined with macroporous resin column separation, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2013, 第 1 作者
（29） INDIUM-PROMOTED ALLYLATION OF ALKYNES WITH ALLYLIC ALCOHOLS: HIGHLY REGIOSELECTIVE SYNTHESIS OF HALOGEN-SUBSTITUTED 1,4-DIENES, SYNTHETIC COMMUNICATIONS, 2013, 第 1 作者
（30） Preparative Isolation and Purification of Three Stilbene Glycosides from the Tibetan Medicinal Plant Rheum tanguticum Maxim. Ex Balf. by High-speed Counter-current Chromatography, PHYTOCHEMICAL ANALYSIS, 2013, 第 4 作者
（31） Sp3-sp2 C-C bond formation via Br��nsted acid TfOH-catalyzed direct coupling reaction of alcohols and alkenes, Adv. Synth. Catal., 2011, 第 1 作者

   

（ 1 ） 高原特色植物（白刺）有效成分与生态环境相关研究, 负责人, 研究所自主部署, 2023-01--2025-12
（ 2 ） 柴达木白刺中苯丙氨酸和色氨酸类衍生物发现及其降血糖活性研究, 负责人, 地方任务, 2022-01--2024-12
（ 3 ） 唐古特白刺果实中α-葡萄糖苷酶抑制剂的发现及其降血糖作用机制研究, 负责人, 国家任务, 2020-01--2022-12
（ 4 ） 大花红景天中α-葡萄糖苷酶抑制剂的发现及其降血糖作用机制研究, 负责人, 中国科学院计划, 2020-01--2024-12
（ 5 ） 基于α-葡萄糖苷酶靶点的白刺等植物抗糖尿病活性物质临床前研究, 负责人, 地方任务, 2019-01--2021-12
（ 6 ） 治疗上呼吸道感染中药巴尔巴达雾化剂关键技术研究, 负责人, 境内委托项目, 2017-09--2019-09
（ 7 ） PhlorigidosideC抗类风湿性关节炎活性及机制研究, 负责人, 地方任务, 2017-01--2019-12
（ 8 ） 独一味抗类风湿性关节炎活性物质基础及机理研究, 负责人, 地方任务, 2013-07--2015-12
（ 9 ） 异叶青兰中抗肿瘤活性成分筛选及结构修饰制研究, 负责人, 中国科学院计划, 2012-12--2016-09