071004-水生生物学
090801-水产养殖

水生病毒及其分子生物学
水生病毒与宿主相互作用

2006-09--2011-06   中国科学院水生生物研究所   理学博士
2002-09--2006-06   武汉大学   理学学士

   

2018-03~现在, 中国科学院水生生物研究所, 副研究员
2011-09~2018-02,河南城建学院, 讲师，副教授
2006-09~2011-06,中国科学院水生生物研究所, 理学博士
2002-09~2006-06,武汉大学, 理学学士

2018-11-29-今,湖北省微生物学会理事,

   

（ 1 ） 一种鳜皮肤细胞系及其应用, 2022, 第 1 作者, 专利号: CN114058566A

（ 2 ） 淡水小龙虾线头病毒PCV-87R特异性序列及应用, 2019, 第 2 作者, 专利号: CN110184385A

（ 3 ） 大菱鲆呼肠孤病毒全基因组及其应用, 2010, 第 2 作者, 专利号: CN101864435A

   

（1） Extra peptidase of a cyanophage confers its stronger lytic effect on bloom-forming Microcystis aeruginosa, Int J Biol Macromol, 2025, 第 1 作者
（2） CRISPR/Cas13d mediated inhibition of Siniperca chuatsi rhabdovirus infection in fish cells, Aquaculture, 2025, 
（3） A novel cell line established from skin tissue of gibel carp (Carassius gibelio) is susceptible to Carassius auratus herpesvirus infection, Water Biology and Security, 2024, 
（4） Advances on genomes studies of large DNA viruses in aquaculture: A minireview, Genomics, 2023, 第 1 作者
（5） Fusing a TurboID tag with the Andrias davidianus ranavirus 2L reduced virus adsorption efficiency, Microb Pathog, 2023, 
（6） Eukaryotic translation elongation factor 1 alpha (eEF1A) inhibits Siniperca chuatsi rhabdovirus (SCRV) infection through two distinct mechanisms, J Virol, 2023, 
（7） Genome characteristics of two ranavirus isolates from mandarin fish and largemouth bass, Pathogens, 2023, 第 12 作者
（8） Development and characterization of a skin cell line from Chinese perch (Siniperca chuatsi) and its application in aquatic animal viruses, JOURNAL OF FISH DISEASES, 2022, 第 5 作者  通讯作者
（9） Replication and transcription machinery for ranaviruses: components, correlation, and functional architecture, CELL & BIOSCIENCE, 2022, 第 1 作者
（10） ADRV 12L: A Ranaviral Putative Rad2 Family Protein Involved in DNA Recombination and Repair, VIRUSES, 2022, 第 1 作者
（11） Andrias davidianus Ranavirus (ADRV) Genome Replicate Efficiently by Engaging Cellular Mismatch Repair Protein MSH2, VIRUSES-BASEL, 2022, 第 1 作者  通讯作者
（12） Environmental Factors and Their Threshold Affecting the Survival of Five Aquatic Animal Viruses in Different Animal Cells, VIRUSES-BASEL, 2022, 第 2 作者
（13） Siniperca chuatsi Rhabdovirus (SCRV)-Induced Key Pathways and Major Antiviral Genes in Fish Cells, MICROORGANISMS, 2022, 第 1 作者  通讯作者
（14） Structural and Functional Diversity among Five RING Finger Proteins from Carassius Auratus Herpesvirus (CaHV), VIRUSES-BASEL, 2021, 第 2 作者
（15） An identified PfHMGB1 promotes microcystin-LR-induced liver injury of yellow catfish (Pelteobagrus fulvidraco), ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2021, 第 7 作者
（16） The features of an emerging whispovirus isolate from freshwater crayfish, AQUACULTURE REPORTS, 2021, 第 1 作者
（17） Andrias davidianus ranavirus 1R encoding a delayed-early protein promotes cell proliferation by driving cell cycle progression into S phase, ACTA VIROLOGICA, 2020, 
（18） Interaction between cyanophage MaMV-DC and eight Microcystis strains, revealed by genetic defense systems, HARMFUL ALGAE, 2019, 第 6 作者
（19） Ranaviruses Bind Cells from Different Species through Interaction with Heparan Sulfate, VIRUSES-BASEL, 2019, 第 1 作者
（20） Protective effect of Clostridium butyricum against Carassius auratus herpesvirus in gibel carp, AQUACULTURE INTERNATIONAL, 2019, 第 2 作者
（21） PfHMGB2 protects yellow catfish (Pelteobagrus fulvidraco) from bacterial infection by promoting phagocytosis and proliferation of PBL, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 6 作者
（22） Aquatic animal viruses mediated immune evasion in their host, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 1 作者
（23） Ranaviruses Bind Cells from Different Species through Interaction with Heparan Sulfate, VIRUSES, 2019, 第 1 作者
（24） Aquatic animal viruses mediated immune evasion in their host, FISH AND SHELLFISH IMMUNOLOGY, 2019, 第 1 作者
（25） 蛙病毒同源蛋白RGV-27R和ADRV-85L的表达及其免疫原性分析, The Expression and Immunogenic Analysis of Ranaviruses Homologous Proteins RGV-27R and ADRV-85L, 病毒学报, 2019, 第 2 作者
（26） Divergent transcriptomic responses underlying the ranaviruses-amphibian interaction processes on interspecies infection of Chinese giant salamander, BMC GENOMICS, 2018, 第 1 作者
（27） Identification and activity of a paralog of cathepsin S from yellow catfish (Pelteobagrus fulvidraco) involved in immune response, FISH & SHELLFISH IMMUNOLOGY, 2017, 第 5 作者  通讯作者
（28） A tandem-repeat galectin-9 involved in immune response of yellow catfish, Pelteobagrus fulvidraco, against Aeromonas hydrophila, FISH & SHELLFISH IMMUNOLOGY, 2016, 第 2 作者  通讯作者
（29） Molecular cloning and characterization of a C-type lectin in yellow catfish Tachysurus fulvidraco, JOURNAL OF FISH BIOLOGY, 2016, 
（30） Cloning and expression analysis of c-type and g-type lysozymes in yellow cat���sh (Pelteobagrus fulvidraco), Genes & Genomics, 2016, 第 1 作者
（31） Characterization of MMP-9 gene from a normalized cDNA library of kidney tissue of yellow catfish (Pelteobagrus fulvidraco), FISH AND SHELLFISH IMMUNOLOGY, 2015, 第 1 作者
（32） Bibliometric analysis of research on microcystins in China and worldwide from 1991 to 2011, DESALINATION AND WATER TREATMENT, 2015, 第 3 作者
（33） Complete genome sequence and comparative analysis of grass carp reovirus strain 109 (GCReV-109) with other grass carp reovirus strains reveals no significant correlation with regional distribution, ARCHIVES OF VIROLOGY, 2014, 第 2 作者
（34） Rana grylio virus (RGV) envelope protein 2L: subcellular localization and essential roles in virus infectivity revealed by conditional lethal mutant, JOURNAL OF GENERAL VIROLOGY, 2014, 第 2 作者
（35） A conditional lethal mutation in Rana grylio virus ORF 53R resulted in a marked reduction in virion formation, VIRUS RESEARCH, 2013, 第 3 作者
（36） Nonstructural Protein NS80 Is Crucial in Recruiting Viral Components to Form Aquareoviral Factories, PLOS ONE, 2013, 第 1 作者
（37） Rana grylio virus as a vector for foreign gene expression in fish cells, VIRUS RESEARCH, 2012, 第 2 作者
（38） Turbot reovirus (SMReV) genome encoding a FAST protein with a non-AUG start site, BMC GENOMICS, 2011, 第 1 作者
（39） Genome of turbot rhabdovirus exhibits unusual non-coding regions and an additional ORF that could be expressed in fish cell, VIRUS RESEARCH, 2011, 第 3 作者
（40） Viral Envelope Protein 53R Gene Highly Specific Silencing and Iridovirus Resistance in Fish Cells by AmiRNA, PLOS ONE, 2010, 第 2 作者
（41） 蛙虹彩病毒一个序列保守基因（RGV-12L）的克隆表达及定位分析, CLONING, EXPRESSION AND LOCALIZATION ANALYSIS OF A SEQUENCE CONSERVED GENE (RGV-12L) FROM RANA GRYLIO VIRUS, 水生生物学报, 2010, 第 2 作者
（42） Effect of beta-glucan on activity of antioxidant enzymes and Mx gene expression in virus infected grass carp, FISH & SHELLFISH IMMUNOLOGY, 2009, 第 2 作者
（43） Cloning, expression and subcellular distribution of a Rana grylio virus late gene encoding ERV1 homologue, MOLECULAR BIOLOGY REPORTS, 2009, 第 1 作者
（44） Rana grylio virus thymidine kinase gene: an early gene of iridovirus encoding for a cytoplasmic protein, VIRUS GENES, 2009, 第 2 作者
（45） Lcdv-C胸苷酸合酶基因在鱼类细胞转化和肿瘤形成中的作用, 第七届全国病毒学学术研讨会暨第二届武汉现代病毒学国际研讨会论文集, 2008, 第 2 作者
（46） Identification and characterization of a novel envelope protein in Rana grylio virus, JOURNAL OF GENERAL VIROLOGY, 2008, 第 2 作者
（47） Constitutive expression of thymidylate synthase from LCDV-C induces a transformed phenotype in fish cells, VIROLOGY, 2008, 第 3 作者
（48） 蛙虹彩病毒中一个erv1/Alr家族基因的鉴定, 第七届全国病毒学学术研讨会暨第二届武汉现代病毒学国际研讨会论文集, 2008, 第 1 作者
（49） 养殖大菱鲆中一种球形病毒的分离及超微观察, “环境与健康”学术研讨会论文摘要集, 2008, 第 1 作者
（50） Isolation, characterization and genome sequence of a birnavirus strain from flounder Paralichthys olivaceus in China, ARCHIVES OF VIROLOGY, 2008, 第 2 作者
（51） 蛙虹彩病毒cop基因的克隆表达及亚细胞定位, Cloning, Expression and Subcellular Localization of cop Gene of Rana grylio Virus (RGV), 武汉大学学报：理学版, 2007, 第 1 作者
（52） Characterization of an early gene encoding for dUTPase in Rana grylio virus, VIRUS RESEARCH, 2007, 第 2 作者

   

（ 1 ） 鲫鲤急性出血病致病与免疫机制研究, 负责人, 中国科学院计划, 2023-12--2028-11
（ 2 ） 淡水鱼类抗病性状形成及网络调控研究, 参与, 国家任务, 2023-01--2027-12
（ 3 ） 蛙病毒DNA聚合酶及其辅助因子PCNA在病毒基因组复制及差异化感染中的功能研究, 负责人, 国家任务, 2020-01--2023-12
（ 4 ） 草鱼和鲫抗病品种的精准设计, 参与, 中国科学院计划, 2019-11--2024-12
（ 5 ） 鳜抗病毒病的关键免疫应答调控元件及其遗传基础研究, 参与, 国家任务, 2018-12--2022-12
（ 6 ） 养殖鱼类疫病预警与防控, 负责人, 研究所自主部署, 2018-11--2023-10

（1）Investigation of binding and replication of RGV and ADRV   2019-06-04