071010-生物化学与分子生物学

化学生物学及生物物理化学

2002-09--2005-07   清华大学   理学博士学位

   

2002-09~2005-07,清华大学, 理学博士学位

   

（1） Whole-cell-catalyzed hydrogenation/deuteration of aryl halides with a genetically repurposed photodehalogenase, CHEM, 2023, 第 2 作者
（2） Genetically Encoded Phosphine Ligand for Metalloprotein Design, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 第 6 作者  通讯作者
（3） Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser, NATURE CHEMISTRY, 2022, 第 1 作者
（4） A Genetically Encoded Two-Dimensional Infrared Probe for Enzyme Active-Site Dynamics, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 第 11 作者  通讯作者
（5） Rational Design of a Miniature Photocatalytic CO2-Reducing Enzyme, ACS CATALYSIS, 2021, 第 11 作者  通讯作者
（6） Single-molecule FRET and conformational analysis of beta-arrestin-1 through genetic code expansion and a Se-click reaction, CHEMICAL SCIENCE, 2021, 第 6 作者
（7） Biocatalytic Cross-Coupling of Aryl Halides with a Genetically Engineered Photosensitizer Artificial Dehalogenase, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 第 4 作者  通讯作者
（8） 光诱导漆酶催化二氧化碳还原, Photo induced carbon dioxide reduction by laccase, 河北工业大学学报, 2021, 第 3 作者
（9） "Single-molecule FRET and conformational analysis of betaarrestin- 1 through genetic code expansion and Se-Click reaction", Chemical Science, 2021, 第 6 作者
（10） Electrostatics affect the glow, SCIENCE, 2020, 第 2 作者
（11） Coupling natural systems with synthetic chemistry for light-driven enzymatic biocatalysis, PHOTOSYNTHESIS RESEARCH, 2020, 第 3 作者
（12） Expansion of Redox Chemistry in Designer Metalloenzymes, ACCOUNTS OF CHEMICAL RESEARCH, 2019, 第 2 作者
（13） A genetically engineered Escherichia coli that senses and degrades tetracycline antibiotic residue, A genetically engineered Escherichia coli that senses and degrades tetracycline antibiotic residue, SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2018, 第 16 作者
（14） Significant expansion and red-shifting of fluorescent protein chromophore determined through computational design and genetic code expansion, Biophysics Reports, 2018, 第 12 作者
（15） A genetically encoded photosensitizer protein facilitates the rational design of a miniature photocatalytic CO2-reducing enzyme, NATURE CHEMISTRY, 2018, 第 1 作者
（16） Heme copper oxidase design using genetic code expansion, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 第 1 作者
（17） Synthetic Model of the Oxygen-Evolving Center: Photosystem II under the Spotlight, CHEMBIOCHEM, 2015, 第 3 作者
（18） Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid, CHEMICAL SCIENCE, 2015, 第 4 作者
（19） A DesignedMetalloenzyme Achieving the Catalytic Rateof a Native Enzyme, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 第 3 作者
（20） Ultrafast Photoinduced Electron Transfer in Green Fluorescent Protein Bearing a Genetically Encoded Electron Acceptor, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 第 7 作者
（21） Significant Expansion of Fluorescent Protein Sensing Ability through the Genetic Incorporation of Superior Photo-Induced Electron-Transfer Quenchers, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 第 1 作者
（22） Significant Expansion of the Fluorescent Protein Chromophore through the Genetic Incorporation of a Metal-Chelating Unnatural Amino Acid, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 第 1 作者
（23） Significant Increase of Oxidase Activity through the Genetic Incorporation of a Tyrosine-Histidine Cross-Link in a Myoglobin Model of Heme-Copper Oxidase, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 第 1 作者
（24） Genetic Incorporation of a Metal-Chelating Amino Acid as a Probe for Protein Electron Transfer, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 第 1 作者

   

（ 1 ） 基于化学/生物自组装的手段实现自由基SAM酶催化功能的调控, 负责人, 国家任务, 2022-01--2026-12
（ 2 ） 酶化学生物学, 负责人, 国家任务, 2022-01--2026-12