基本信息
顾奇  男  博导  中国科学院动物研究所
email: qgu@ioz.ac.cn
address: 朝阳区大屯路甲3号干细胞大楼
postalCode:

招生信息

   
招生专业
083100-生物医学工程
招生方向
生物制造,生物医学工程
生物材料,3D/4D生物打印
器官重建

教育背景

2013-10--2017-11   University of Wollongong   博士
2005-09--2013-06   东北农业大学   本硕博连读

工作经历

   
工作简历
2013-10~2017-11,University of Wollongong, 博士
2005-09~2013-06,东北农业大学, 本硕博连读
社会兼职
2023-04-30-今,BMEMat,
2022-11-22-今,第三届航天医学工程与空间生物学专委会,
2022-05-31-今,Bioactive Materials,
2022-01-01-今,中国科学院高端光学显微成像技术联盟,
2020-12-31-今,中国空间科学学会,

专利与奖励

   
专利成果
( 1 ) 一种微载体及其应用, 2023, 第 1 作者, 专利号: CN116496970A

( 2 ) 一种基于微凝胶的生物打印基质, 2023, 第 1 作者, 专利号: CN 202310198755.6

( 3 ) 一种生物墨水及其制备方法和应用, 2023, 第 1 作者, 专利号: CN 2023101208913

( 4 ) 一种可用于实质组织功能补偿的可移植装置, 2022, 第 1 作者, 专利号: CN 202211233551.3

( 5 ) 一种人源的3D生物墨水及其制备方法和用途, 2022, 第 1 作者, 专利号: CN 202210642274.5

( 6 ) 用于胚胎培养的培养皿, 2022, 第 7 作者, 专利号: CN114369531A

( 7 ) 胚胎培养和监测系统, 2022, 第 2 作者, 专利号: CN216274172U

( 8 ) 一种病毒富集装置及医疗诊断装置, 2022, 第 1 作者, 专利号: CN111991031B

( 9 ) 一种微载体及其应用, 2022, 第 1 作者, 专利号: CN 202210055720.2

( 10 ) 便携式荧光检测设备及诊断方法, 2021, 第 3 作者, 专利号: CN113203715A

( 11 ) 一种制备各向异性水凝胶的方法, 2021, 第 3 作者, 专利号: CN112708146A

( 12 ) 胚胎培养装置, 2021, 第 4 作者, 专利号: CN112662553A

( 13 ) 胚胎培养和监测系统, 2021, 第 2 作者, 专利号: CN112522092A

( 14 ) 一种诱导多能性干细胞的培养体系, 2015, 第 2 作者, 专利号: CN104928251A

( 15 ) 一种诱导多能干细胞的培养基及其用途, 2014, 第 3 作者, 专利号: CN104195103A

出版信息

   
发表论文
(1) A scalable culture system incorporating microcarrier for specialised mesenchymal stem cells from human embryonic stem cells, MATERIALS TODAY BIO, 2023, 第 11 作者
(2) Vascularized organ bioprinting: From strategy to paradigm, CELL PROLIFERATION, 2023, 第 11 作者
(3) Collagen for neural tissue engineering: Materials, strategies, and challenges, MATERIALS TODAY BIO, 2023, 第 7 作者
(4) Synthesis of Easily-Processable Collagen Bio-inks using Ionic Liquid for 3D Bioprinted Liver Tissue Models with Branched Vascular Networks, 中国科学:化学(英文版), 2023, 第 11 作者
(5) Cartilage Lacuna-Inspired Microcarriers Drive Hyaline Neocartilage Regeneration, Advanced Materials, 2023, 第 11 作者
(6) 3D bioprinting microgels to construct implantable vascular tissue, Cell Proliferation, 2023, 第 11 作者
(7) Controllable assembly of skeletal muscle-like bundles through 3D bioprinting, BIOFABRICATION, 2022, 第 11 作者
(8) Bioink derived from human placenta supporting angiogenesis, BIOMEDICAL MATERIALS, 2022, 第 11 作者
(9) The evolution of conglobation in Ceratocanthinae, COMMUNICATIONS BIOLOGY, 2022, 第 11 作者
(10) Stretchable Electronic Facial Masks for Sonophoresis, ACS NANO, 2022, 第 0 作者
(11) Valve-based consecutive bioprinting method for multimaterial tissue-like constructs with controllable interfaces, BIOFABRICATION, 2021, 第 9 作者
(12) Reconstruction of functional uterine tissues through recellularizing the decellularized rat uterine scaffolds by MSCs in vivo and in vitro, BIOMEDICAL MATERIALS, 2021, 第 11 作者
(13) Hybrid Gelatin Hydrogels in Nanomedicine Applications, ACS APPLIED BIO MATERIALS, 2021, 第 11 作者
(14) 3D Liver Tissue Model with Branched Vascular Networks by Multimaterial Bioprinting, ADVANCED HEALTHCARE MATERIALS, 2021, 第 11 作者
(15) Engineering in vitro human neural tissue analogs by 3D bioprinting and electrostimulation, APL BIOENGINEERING, 2021, 
(16) SELECTIVE REACTION OF CONJUGATED POLYMERS WITH BASIC PROTEINS FOR BROAD-SPECTRUM ANTIVIRULENCE THERAPY, NPG ASIA MATERIALS, 2021, 第 5 作者
(17) Conducting Polymer Mediated Electrical Stimulation Induces Multilineage Differentiation with Robust Neuronal Fate Determination of Human Induced Pluripotent Stem Cells, CELLS, 2020, 第 2 作者
(18) Supramolecular Nanofibers for Encapsulation and In Situ Differentiation of Neural Stem Cells, ADVANCED HEALTHCARE MATERIALS, 2020, 第 11 作者
(19) Effects of Different Biomaterials and Cellular Status on Testicular Cell Self-Organization, ADVANCED BIOSYSTEMS, 2020, 第 11 作者
(20) Fibrin Facilitates Mesenchymal Stem Cells to Ameliorate Rats with Polycystic Ovary Syndrome, APPLIED SCIENCES-BASEL, 2020, 第 11 作者
(21) 弹性蛋白样生物材料的制备及性质鉴定, Identification and Expression of Elastin-like Polypeptides, 中国生物工程杂志, 2020, 第 4 作者
(22) Bioengineered microenvironment to culture early embryos, Cell Proliferation, 2020, 第 11 作者
(23) Reactive Amphiphilic Conjugated Polymers for Inhibiting Amyloid Assembly, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 第 11 作者
(24) The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies, PROTEIN & CELL, 2019, 第 3 作者
(25) Reactive Amphiphilic Conjugated Polymers for Inhibiting Amyloid beta Assembly, ANGEWANDTE CHEMIE INTERNATIONAL EDITION, 2019, 第 8 作者
(26) Grob-Fragmentation-Enabled Approach to Clavulactone Analogues, ORGANIC LETTERS, 2019, 第 1 作者
(27) Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions, CELLDEATHDISEASE, 2019, 第 12 作者
(28) A Facile Method to Fabricate Anisotropic Extracellular Matrix with 3D Printing Topological Microfibers, MATERIALS, 2019, 第 11 作者
(29) The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies, The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies, 蛋白质与细胞:英文版, 2019, 第 3 作者
(30) A non-enzymatic photoelectrochemical glucose sensor based on BiVO4 electrode under visible light, SENSORS AND ACTUATORS B-CHEMICAL, 2019, 第 8 作者
(31) Conjugated Polymer Nanoparticles with Appended Photo-Responsive Units for Controlled Drug Delivery, Release, and Imaging, ANGEWANDTECHEMIEINTERNATIONALEDITION, 2018, 第 3 作者
(32) A fully defined static suspension culture system for large-scale human embryonic stem cell production, CELL DEATH AND DISEASE, 2018, 第 3 作者
(33) Conjugated Polymer Materials for Photothermal Therapy, ADVANCED THERAPEUTICS, 2018, 第 11 作者
(34) A fully defined static suspension culture system for large-scale human embryonic stem cell production, CELL DEATH & DISEASE, 2018, 第 3 作者
(35) Conductive Tough Hydrogel for Bioapplications, MACROMOLECULAR BIOSCIENCE, 2018, 第 2 作者
(36) Generation of clinical-grade functional cardiomyocytes from human embryonic stem cells in chemically defined conditions, JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2018, 第 3 作者
(37) Effect of electrochemical oxidation and reduction on cell de-adhesion at the conducting polymer-live cell interface as revealed by single cell force spectroscopy, BIOINTERPHASES, 2018, 第 2 作者
(38) Local structural evolutions of CuO/ZnO/Al2O3 catalyst for methanol synthesis under operando conditions studied by in situ quick X-ray absorption spectroscopy, Local structural evolutions of CuO/ZnO/Al2O3 catalyst for methanol synthesis under operando conditions studied by in situ quick X-ray absorption spectroscopy, 核技术:英文版, 2017, 
(39) Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations, STEM CELL REPORTS, 2017, 第 1 作者
(40) Development of Drug-Loaded Polymer Microcapsules for Treatment of Epilepsy, BIOMATERIALS SCIENCE, 2017, 第 2 作者
(41) Bioprinting Human Induced Pluripotent Stem Cell Constructs For In Situ Cell Proliferation and Successive Multi-Lineage Differentiation, Advanced Healthcare Materials, 2017, 第 1 作者
(42) 3D Bioprinting Human Induced Pluripotent Stem Cell Constructs for In Situ Cell Proliferation and Successive Multilineage Differentiation, ADVANCED HEALTHCARE MATERIALS, 2017, 第 1 作者
(43) Three-dimensional bioprinting speeds up smart regenerative medicine, NATIONAL SCIENCE REVIEW, 2016, 第 1 作者
(44) Soller slits automatic focusing method for multi-element fluorescence detector, Soller slits automatic focusing method for multi-element fluorescence detector, 核技术:英文版, 2016, 
(45) Efficient Derivation of Human Induced Pluripotent Stem Cells with a c-Myc-Free Non-Integrating Episomal Vector, JOURNALOFGENETICSANDGENOMICS, 2016, 第 2 作者
(46) Functional 3D Neural Mini-Tissues from Printed Gel-Based Bioink and Human Neural Stem Cells, ADVANCED HEALTHCARE MATERIALS, 2016, 第 1 作者
(47) Three Dimensional Collagen Scaffolds Promote iPSC Induction with Higher Pluripotency, PROTEIN & CELL, 2016, 第 1 作者
(48) Generation of clinical-grade human induced pluripotent stem cells in Xeno-free conditions, STEM CELL RESEARCH & THERAPY, 2015, 第 4 作者
(49) 生物三维打印的研究进展, 中国科学:生命科学, 2015, 第 1 作者
(50) Efficient Generation of Mouse ESCs-Like Pig Induced Pluripotent Stem Cells, PROTEIN & CELL, 2014, 第 1 作者
(51) Genetic Modification and Screening in Rat Using Haploid Embryonic Stem Cells, CELL STEM CELL, 2014, 第 12 作者
(52) Generation of Induced Pluripotent Stem Cells with High Efficiency from Human Umbilical Cord Blood Mononuclear Cells, GENOMICS, PROTEOMICS & BIOINFORMATICS, 2013, 第 2 作者
(53) Derivation of Androgenetic Embryonic Stem Cells from M-Carboxycinnamic Acid Bishydroxamide (CBHA) Treated Androgenetic Embryos, CHINESE SCIENCE BULLETIN, 2013, 第 4 作者
(54) Tbx3 and Nr5 alpha 2 Play Important Roles in Pig Pluripotent Stem Cells, STEM CELL REVIEWS AND REPORTS, 2013, 第 2 作者
(55) Generation of Induced Pluripotent Stem Cells with High Efficiency from Human Umbilical Cord Blood Mononuclear Cells, Generation of Induced Pluripotent Stem Cells with High Efficiency from Human Umbilical Cord Blood Mononuclear Cells, 基因组蛋白质组与生物信息学报:英文版, 2013, 第 2 作者
(56) Directed neuronal differentiation of mouse embryonic and induced pluripotent stem cells and their gene expression profiles, INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2013, 第 2 作者
(57) Rapid conversion of human ESCs into mouse ESC-like pluripotent state by optimizing culture conditions, PROTEIN & CELL, 2012, 第 1 作者
(58) Microcarriers promote the through interface movement of mouse trophoblast stem cells by regulating stiffness, BIOACTIVE MATERIALS, 第 10 作者
(59) COMMUNICATIONS BIOLOGY, 第 17 作者

科研活动

   
科研项目
( 1 ) 器官重建与制造, 负责人, 国家任务, 2023-01--2025-12
( 2 ) 标准化研究项目, 负责人, 国家任务, 2019-08--2023-07
( 3 ) 功能性生物打印“墨水”及个性化生物3D打印装置研发, 负责人, 中国科学院计划, 2017-11--2022-11
参与会议
(1)生物仿生制造与三维细胞运动   2023全国生物制造工程学术年会暨生物制造国际研讨会   2023-03-19
(2)器官制造与细胞运动   第六次全国基质生物学学术会议邀请报告   2022-11-04
(3)宏观制造与微观运动   2021-2022中国生物医学工程大会暨创新医疗峰会   2022-04-11
(4)生物仿生制造与三维细胞运动   第三届中国组织器官再生研讨会   2021-03-25
(5)3D Printing Human iPSCs to Produce Functional Tissues   2017-01-26
(6)3D printing human iPSCs for neural tissue engineering   2016-11-08
(7)3D printing stem cells   2015-10-30