基本信息
张晓明  男  博导  中国科学院昆明动物研究所
email: zhangxiaoming@mail.kiz.ac.cn
address: 中国科学院昆明动物研究所
postalCode: 750223

招生信息

   
招生专业
071007-遗传学
0710Z1-基因组学
0710J3-生物信息学
招生方向
人类的进化与环境适应,群体遗传学
基因组学, 生物信息学
古DNA,史前人类多样性,史前动物多样性

工作经历

   
工作简历
2021-10~现在, 中国科学院昆明动物研究所, 研究员(四级)
2018-01~2021-09,中国科学院昆明动物研究所, 副研究员二级
2015-10~2017-12,中国科学院昆明动物研究所, 副研究员三级

专利与奖励

   
奖励信息
(1) 细胞出版社2020中国年度论文, 其他, 2021
(2) 云南省优秀博士论文奖, 省级, 2016
(3) 中国科学院院长奖优秀奖, , 院级, 2014

出版信息

   
发表论文
(1) A Late Pleistocene human genome from Southwest China, CURRENT BIOLOGY, 2022, 第 1 作者
(2) The distinct morphological phenotypes of Southeast Asian aborigines are shaped by novel mechanisms for adaptation to tropical rainforests, National Science Review, 2021, 
(3) A Matrilineal Genetic Perspective of Hanging Coffin Custom in Southern China and Northern Thailand, ISCIENCE, 2020, 第 1 作者
(4) Ancient genomes reveal tropical bovid species in the Tibetan Plateau contributed to the prevalence of hunting game until the late Neolithic, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 通讯作者
(5) Genomic analyses reveal distinct genetic architectures and selective pressures in buffaloes, GIGASCIENCE, 2020, 第 9 作者
(6) The Transcriptomic Landscape of Yaks Reveals Molecular Pathways for High Altitude Adaptation, GENOME BIOLOGY AND EVOLUTION, 2019, 第 5 作者
(7) Blunted nitric oxide regulation in Tibetans under high-altitude hypoxia, NATIONAL SCIENCE REVIEW, 2018, 第 23 作者
(8) Whole-genome resequencing reveals world-wide ancestry and adaptive introgression events of domesticated cattle in East Asia, NATURE COMMUNICATIONS, 2018, 第 21 作者
(9) Darwinian Positive Selection on the Pleiotropic Effects of KITLG Explain Skin Pigmentation and Winter Temperature Adaptation in Eurasians, MOLECULAR BIOLOGY AND EVOLUTION, 2018, 第11作者
(10) EP300 contributes to high-altitude adaptation in Tibetans by regulating nitric oxide production, ZOOLOGICAL RESEARCH, 2017, 第 20 作者
(11) GCH1 plays a role in the high-altitude adaptation of Tibetans, ZOOLOGICAL RESEARCH, 2017, 第 20 作者
(12) Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia, MOLECULAR BIOLOGY AND EVOLUTION, 2017, 其他(合作组作者)
(13) Sherpas share genetic variations with Tibetans for high-altitude adaptation, MOLECULAR GENETICS & GENOMIC MEDICINE, 2017, 第 2 作者
(14) Cross-altitude analysis suggests a turning point at the elevation of 4,500m for polycythemia prevalence in tibetans., AMERICAN JOURNAL OF HEMATOLOGY, 2017, 第 19 作者
(15) A Genetic Mechanism for Convergent Skin Lightening during Recent Human Evolution, MOLECULAR BIOLOGY AND EVOLUTION, 2016, 第 4 作者
(16) HMOX2 Functions as a Modifier Gene for High-Altitude Adaptation in Tibetans, HUMAN MUTATION, 2016, 第11作者
(17) Y-chromosome diversity suggests southern origin and Paleolithic backwave migration of Austro-Asiatic speakers from eastern Asia to the Indian subcontinent, SCIENTIFIC REPORTS, 2015, 第 1 作者
(18) Genetic evidence of a recent Tibetan ancestry to Sherpas in the Himalayan region, SCIENTIFIC REPORTS, 2015, 第 2 作者
(19) An Updated Phylogeny of the Human Y-Chromosome Lineage O2a-M95 with Novel SNPs, PLOS ONE, 2014, 第 1 作者
(20) Genetic Evidence of Paleolithic Colonization and Neolithic Expansion of Modern Humans on the Tibetan Plateau, MOLECULAR BIOLOGY AND EVOLUTION, 2013, 第 4 作者
(21) Analysis of mitochondrial genome diversity identifies new and ancient maternal lineages in Cambodian aborigines, NATURE COMMUNICATIONS, 2013, 第 1 作者
(22) Identification of a Tibetan-Specific Mutation in the Hypoxic Gene EGLN1 and Its Contribution to High-Altitude Adaptation, MOLECULAR BIOLOGY AND EVOLUTION, 2013, 第 5 作者
(23) Genetic Evidence of an East Asian Origin and Paleolithic Northward Migration of Y-chromosome Haplogroup N, PLOS ONE, 2013, 第 5 作者

科研活动

   
科研项目
( 1 ) 东南亚土著人群的源流历史与特征表型适 应性进化的遗传学研究, 负责人, 国家任务, 2019-01--2022-12
( 2 ) 云南省“万人计划”青年拔尖人才, 负责人, 地方任务, 2020-01--2025-12
( 3 ) 东亚早期人类的表型演化分子机制与群体历史, 负责人, 国家任务, 2023-01--2025-12
( 4 ) AAAAABBBBCCCC(BM项目), 负责人, 国家任务, 2022-11--2025-10