基本信息
夏兵 男 硕导 中国科学院成都生物研究所
电子邮件: xiabing@cib.ac.cn
通信地址: 四川省成都市高新区科园南路93号
邮政编码:
电子邮件: xiabing@cib.ac.cn
通信地址: 四川省成都市高新区科园南路93号
邮政编码:
招生信息
招生专业
100701-药物化学
招生方向
药物分析,天然产物分析,液质联用分析,开源离子源研究
教育背景
2008-09--2012-07 中国科学院成都生物研究所 理学博士2007-09--2008-07 中国科技大学 无2003-09--2007-07 东北大学 理学学士
工作经历
工作简历
2014-10~现在, 中国科学院成都生物研究所, 高级工程师(副高级)2012-07~2014-10,中国科学院成都生物研究所, 工程师2008-09~2012-07,中国科学院成都生物研究所, 理学博士2007-09~2008-07,中国科技大学, 无2003-09~2007-07,东北大学, 理学学士
专利与奖励
专利成果
( 1 ) 分离人血清中脂溶性维生素并检测各组分含量的方法, 2023, 第 4 作者, 专利号: CN116609446A( 2 ) 电喷雾的激发装置, 2022, 第 2 作者, 专利号: CN216749804U( 3 ) 电喷雾的激发装置及离子化方法, 2022, 第 2 作者, 专利号: CN114496717A( 4 ) CNT@COF THB-TAPB 吸附剂及其在在线固相萃取与质谱联用装置中的应用, 2021, 第 2 作者, 专利号: CN113624866A( 5 ) 基于小数据集的可用于非靶向危害物筛查的色谱条件快速开发方法, 2021, 第 2 作者, 专利号: CN113376283A( 6 ) 一维线材样品转储及质谱分析的装置和使用方法, 2021, 第 2 作者, 专利号: CN113049663A( 7 ) 一种集微柱与微球为一体的电喷雾装置及方法, 2021, 第 2 作者, 专利号: CN110047731B( 8 ) 多层纸芯片结构、制造设备和方法以及流体层间流动方法, 2021, 第 2 作者, 专利号: CN109012770B( 9 ) 一种基于超声振动的分子解吸离子化系统及方法, 2020, 第 2 作者, 专利号: CN111710587A( 10 ) 一种微珠电喷雾阵列高通量分析装置, 2020, 第 2 作者, 专利号: CN210467762U( 11 ) 一种微珠电喷雾阵列高通量分析装置及方法, 2019, 第 2 作者, 专利号: CN110491768A( 12 ) 一种集微柱与微球为一体的电喷雾装置及方法, 2019, 第 2 作者, 专利号: CN110047731A( 13 ) 一种自动清洗装置, 2019, 第 3 作者, 专利号: CN109909245A( 14 ) 一种自动清洗装置, 2019, 第 3 作者, 专利号: CN109909245A( 15 ) 一种清洗结构及利用该结构的自动清洗装置, 2019, 第 3 作者, 专利号: CN208976452U( 16 ) 一种自动清洗装置, 2018, 第 3 作者, 专利号: CN108356010A( 17 ) 一种自动清洗装置, 2017, 第 3 作者, 专利号: CN107350253A( 18 ) 化合物快速电分离装置及实现快速电分离质谱检测的方法, 2017, 第 2 作者, 专利号: CN107064279A( 19 ) 一种基于微球的电喷雾装置, 2016, 第 1 作者, 专利号: CN205542702U( 20 ) 一种基于微球的电喷雾装置及方法, 2016, 第 1 作者, 专利号: CN105679638A( 21 ) 一种基于导电纳米材料的电喷雾质谱装置及其实现电喷雾质谱分析的方法, 2016, 第 2 作者, 专利号: CN105575755A( 22 ) 耐盐液相色谱电喷雾质谱联用接口装置及其使用方法, 2016, 第 1 作者, 专利号: CN105259273A( 23 ) 一种高分辨质谱准确分子式预测方法, 2014, 第 1 作者, 专利号: CN103792275A
出版信息
发表论文
(1) Development and application of a comprehensive nontargeted screening strategy for aristolochic acid analogues, Analytical Chemistry, 2024, 第 6 作者 通讯作者(2) Pulsed Direct Current Arc-Induced Nanoelectrospray Ionization Mass Spectrometry, Analytical Chemistry, 2024, 第 5 作者 通讯作者(3) Rapid analysis of the chemical constituents of traditional Tibetan medicine Sbyor���bzo���ghi���wang using ballpoint electrospray ionization technique, Rapid Communications in Mass Spectrometry, 2024, 第 6 作者(4) Microdroplet accelerated reaction for high-efficiency carbon disulfide conversion, Chemical Communications, 2023, 第 2 作者 通讯作者(5) Determination of 63 mycotoxins in grain products by ultrahigh-performance liquid chromatography coupled with quadrupole-Orbitrap mass spectrometry, FOOD CONTROL, 2023, 第 6 作者(6) Rapid recognition and targeted isolation of potential anti���breast cancer xanthones in Hypericum bellum Li by "seed" mass spectra���based molecular networking and in silico MS/MS fragmentation, Phytochemical Analysis, 2023, 第 3 作者(7) Automated high���throughput characterization of microbial metabolites and species using array ballpoint electrospray ionization technique, Rapid Communications in Mass Spectrometry, 2023, 第 4 作者 通讯作者(8) A novel functionalized covalent organic framework/carbon nanotube composite as an effective online solid-phase extraction sorbent for simultaneous detection of 33 steroid hormones in pork, FOOD CHEMISTRY, 2022, 第 4 作者(9) Purification and mass spectrometry study of Maillard reaction impurities in five acyclic nucleoside antiviral drugs, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2022, 第 5 作者 通讯作者(10) Performing 2D-1D-2D Mass Spectrometry Imaging Using Strings, Analytical Chemistry, 2022, 第 2 作者 通讯作者(11) Study on the separation mechanism of solid-substrate electrospray ionization mass spectrometry, JOURNAL OF SEPARATION SCIENCE, 2021, 第 4 作者(12) Ultrasonic Sputter Desorption Mass Spectrometry Technique for Minimally Invasive Tissue Analysis, ANALYTICAL CHEMISTRY, 2021, 第 3 作者 通讯作者(13) Rapid screening of 70 colorants in dyeable foods by using ultra-high-performance liquid chromatography���hybrid quadrupole���Orbitrap mass spectrometry with customized accurate-mass database and mass spectral library, FOOD CHEMISTRY, 2021, 第 5 作者(14) Corrigendum to "A 6/5/5/7 heterotetracyclic indole derivative alkaloid isolated from Typhonium giganteum" Tetrahedron Lett. (2020) 151497, TETRAHEDRON LETTERS, 2020, 第 5 作者(15) Extensive screening of cyclopeptide toxins in mushrooms by ultra-high-performance liquid chromatography coupled with quadrupole-Orbitrap mass spectrometry, FOOD CHEMISTRY, 2020, 第 4 作者(16) Online Scavenging of Trace Analytes in Complex Matrices for Fast Analysis by Carbon Dioxide Bubbling Extraction Coupled with Gas Chromatography-Mass Spectrometry, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020, 第 2 作者(17) High-sensitivity detection of therapeutic drugs in complex biofluids using a packed ballpoint-electrospray ionization technique, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 第 3 作者(18) 基于分子式数据库策略的FM-searcher软件在危害物非目标筛查分子式预测中的应用, Application of FM-Searcher Software to Prediction of Molecular Formula in the Non-target Screening of Hazard Components Based on Molecular Formula Database Strategy, 质谱学报, 2020, 第 4 作者(19) Flow controllable three-dimensional paper-based microfluidic analytical devices fabricated by 3D printing technology, ANALYTICA CHIMICA ACTA, 2019, 第 2 作者 通讯作者(20) Analysis of Compounds Dissolved in Nonpolar Solvents by Electrospray Ionization on Conductive Nanomaterials, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2018, 第 1 作者(21) Low-cost and convenient ballpoint tip-protected liquid-phase microextraction for sensitive analysis of organic molecules in water samples, ANALYTICA CHIMICA ACTA, 2018, 第 2 作者 通讯作者(22) 天然产物的质谱智能解析研究, 中国科学:化学, 2017, 第 1 作者(23) Determination of Sulfonamides in Chicken Muscle by Pulsed Direct Current ElectroSpray Ionization Tandem Mass Spectrometry, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017, 第 3 作者 通讯作者(24) Intelligent interpretation of mass spectra of natural products, SCIENTIA SINICA Chimica, 2017, 第 1 作者(25) 猕猴桃藤山柳化学成分研究, 中草药, 2016, 第 5 作者(26) Analysis of the lithiated leucosceptroids from Leucosceptrum canum to facilitate their identification and differentiation by electrospray ionization tandem mass spectrometry, Rapid Communications in Mass Spectrometry, 2016, 第 2 作者(27) Generating Electrospray Ionization on Ballpoint Tips, ANALYTICAL CHEMISTRY, 2016, 第 2 作者(28) Application of fractionized sampling and stacking for construction of an interface for online heart-cutting two-dimensional liquid chromatography, JOURNALOFCHROMATOGRAPHYA, 2016, 第 2 作者 通讯作者(29) Structural characterization and antiviral effect of a novel polysaccharide PSP-2B from Prunellae Spica, CARBOHYDRATE POLYMERS, 2016, 第 5 作者(30) 质谱智能解析方法的建立及其在天然药物分析中的应用, 中国化学会第二届全国质谱分析学术报告会会议摘要集, 2015, 第 1 作者(31) 质谱-多级质谱联用技术(MS-MS~n)用于茶叶中初级代谢产物的快速鉴定, 中国化学会第二届全国质谱分析学术报告会会议摘要集, 2015, 第 3 作者(32) 应用探针电喷雾串联质谱快速区分裸蒴中微量同分异构体, 中国化学会第十八届全国有机分析及生物分析学术研讨会论文汇编, 2015, 第 2 作者(33) Two new diketopiperazines and a new glucosyl sesterterpene from Alternaria alternata, an endophytic fungi from Ceratostigma griffithii, PHYTOCHEMISTRY LETTERS, 2015, 第 4 作者(34) Development and characterization of a nanodendritic silver-based solid-phase extraction sorbent for selective enrichment of endocrine-disrupting chemicals in water and milk samples, ANALYTICA CHIMICA ACTA, 2015, 第 2 作者(35) 12-Membered Resorcylic Acid Lactones Isolated from Saccharicola bicolor, an Endophytic Fungi from Bergenia purpurascens, NATURAL PRODUCT COMMUNICATIONS, 2015, 第 4 作者(36) Fragmentation of protonated 2-(2-phenylethyl)chromones from agarwood: the diagnostic role of ion/neutral complexes as reactive intermediates, EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2015, 第 2 作者(37) Reversible tuning of the wettability on a silver mesodendritic surface by the formation and disruption of lipid-like bilayers, APPLIED SURFACE SCIENCE, 2015, 第 2 作者(38) Strategy to rapidly discriminate trace isomeric lignan compounds from Gymnotheca chinensis by probe electrospray ionization tandem mass spectrometry, EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2015, 第 2 作者(39) 针尖电喷雾质谱方法用于软膏剂药物的直接分析, 中国化学会第二届全国质谱分析学术报告会会议摘要集, 2015, 第 3 作者(40) 羌活化学成分的UPLC-MS分析, 分析试验室, 2014, 第 2 作者(41) Advanced ultra-performance liquid chromatography-photodiode array-quadrupole time-of-flight mass spectrometric methods for simultaneous screening and quantification of triterpenoids in Poria cocos, FOOD CHEMISTRY, 2014, 第 1 作者(42) Fast Separation Method Development for Supercritical Fluid Chromatography Using an Autoblending Protocol, CHROMATOGRAPHIA, 2014, 第 1 作者(43) Investigation of the Chemical Compositions in Tobacco of Different Origins and Maturities at Harvest by GC-MS and HPLC-PDA-QTOFMS, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 第 1 作者(44) A rapid and highly specific method to evaluate the presence of 2-(2-phenylethyl) chromones in agarwood by supercritical fluid chromatography-mass spectrometry, EUROPEAN JOURNAL OF MASS SPECTROMETRY, 2014, 第 1 作者(45) Non-Target Screening of Veterinary Drugs Using Tandem Mass Spectrometry on SmartMass, JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2013, 第 1 作者(46) Tandem mass spectrometry fragmentation of the protonated 2-(2-phenylethyl)chromones from Agarwood: radical ions versus non-radical ions, JOURNAL OF MASS SPECTROMETRY, 2013, 第 1 作者(47) 沉香中2-(2-苯乙基)色酮类化合物加氢离子的电喷雾串联质谱裂解机理研究, 中国化学会第十七届全国有机分析与生物分析学术研讨会论文集, 2013, 第 1 作者(48) Efficient optimization of ultra-high- performance supercritical fluid chromatographic separation of Rosa sericea by response surface methodology, JOURNAL OF SEPARATION SCIENCE, 2013, 第 3 作者(49) 滇虎榛叶的化学成分及其抗氧化活性研究, 中草药, 2013, 第 3 作者(50) Fast analysis of triterpenoids in Ganoderma lucidum spores by ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry, BIOMEDICAL CHROMATOGRAPHY, 2013, 第 2 作者(51) Two new cyclic diarylheptanoids from the stems of Ostryopsis nobilis, CHINESE CHEMICAL LETTERS, 2013, 第 2 作者(52) Tandem mass spectrometric analysis and density functional theory calculations on the fragmentation behavior of two tetradecanoylingenol regioisomers from Euphorbia wallichii, RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2012, 第 1 作者(53) 基于分子式数据库的高分辨质谱化合物分子式预测方法, 分析试验室, 2012, 第 1 作者(54) Discrimination of the seeds of Notopterygium incisum and Notopterygium franchetii by validated HPLC-DAD���ESI-MS method and principal component analysis, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2011, 第 5 作者(55) Self-assembly of carboxymethyl konjac glucomannan-g-poly(ethylene glycol) and (alpha-cyclodextrin) to biocompatible hollow nanospheres for glucose oxidase encapsulation, CARBOHYDRATE POLYMERS, 2011, 第 2 作者(56) MyMolDB: A Micromolecular Database Solution with Open Source and Free Components, JOURNALOFCOMPUTATIONALCHEMISTRY, 2011, 第 1 作者 通讯作者(57) Preparation and characterization of a poly(ethylene glycol) grafted carboxymethyl konjac glucomannan copolymer, CARBOHYDRATE POLYMERS, 2010, 第 1 作者(58) Semi-permeable nanocapsules of konjac glucomannan-chitosan for enzyme immobilization, INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2008, 第 2 作者
科研活动
科研项目
( 1 ) 多模式高精度质谱成像装置的研制, 负责人, 中国科学院计划, 2023-10--2024-10( 2 ) 微珠电喷雾阵列多形态样品高通量分析装置的开发, 负责人, 中国科学院计划, 2023-01--2024-12( 3 ) 中国科学院青年创新促进会-夏兵, 负责人, 其他国际合作项目, 2019-01--2022-12( 4 ) 中国科学院关键技术人才-夏兵, 负责人, 其他国际合作项目, 2019-01--2021-12( 5 ) 基于质谱碎裂特征的食品化学危害因子非定向筛查技术研究, 负责人, 国家任务, 2018-12--2021-12( 6 ) 基于导电纳米材料的电喷雾离子化机理研究, 负责人, 国家任务, 2017-01--2020-12( 7 ) 质谱高通量自动进样装置研制, 负责人, 中国科学院计划, 2017-01--2018-12( 8 ) 基于计算机辅助分析和液质联用技术的未知食品危害物筛查研究, 负责人, 国家任务, 2014-01--2016-12