基本信息

叶飞 男 硕导 中国科学院近代物理研究所
电子邮件: yefei@impcas.ac.cn
通信地址: 甘肃省兰州市城关区南昌路509号
邮政编码:
电子邮件: yefei@impcas.ac.cn
通信地址: 甘肃省兰州市城关区南昌路509号
邮政编码:
招生信息
招生专业
071011-生物物理学
招生方向
辐射脑损伤防护,辐射远后效应,辐射炎症效应
教育背景
2008-07--2016-06 兰州大学 博士学位
2001-07--2005-06 兰州大学 学士学位
2001-07--2005-06 兰州大学 学士学位
工作经历
工作简历
2008-07~2016-06,兰州大学, 博士学位
2005-09~现在, 中国科学院近代物理研究所, 副研究员
2005-09~现在, 中国科学院近代物理研究所, 副研究员
2001-07~2005-06,兰州大学, 学士学位
2005-09~现在, 中国科学院近代物理研究所, 副研究员
2005-09~现在, 中国科学院近代物理研究所, 副研究员
2001-07~2005-06,兰州大学, 学士学位
专利与奖励
专利成果
( 1 ) 一种阿尔茨海默症预测方法、系统、设备及介质, 2023, 第 3 作者, 专利号: CN117281470A
( 2 ) 利用自噬抑制剂氯喹提高离子束治疗肿瘤疗效的方法, 2016, 第 7 作者, 专利号: CN105250296A
( 3 ) 小鼠脑组织蛋白质组分析的样品制备方法, 2015, 第 3 作者, 专利号: CN104880546A
( 4 ) 一种利用高能离子束辐照时减小离子束展宽Bragg峰后沿剂量半影的方法, 2010, 第 7 作者, 专利号: CN101763909A
( 2 ) 利用自噬抑制剂氯喹提高离子束治疗肿瘤疗效的方法, 2016, 第 7 作者, 专利号: CN105250296A
( 3 ) 小鼠脑组织蛋白质组分析的样品制备方法, 2015, 第 3 作者, 专利号: CN104880546A
( 4 ) 一种利用高能离子束辐照时减小离子束展宽Bragg峰后沿剂量半影的方法, 2010, 第 7 作者, 专利号: CN101763909A
出版信息
发表论文
(1) Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy, EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 第 3 作者
(2) Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy, EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 第 3 作者
(3) Mitochondrial-Targeted Antioxidant MitoQ-Mediated Autophagy: A Novel Strategy for Precise Radiation Protection, ANTIOXIDANTS, 2023, 第 4 作者
(4) PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis, JOURNAL OF CANCER, 2022, 第 6 作者
(5) Hyperthermia ablation combined with transarterial chemoembolization versus monotherapy for hepatocellular carcinoma: A systematic review and meta-analysis, CANCER MEDICINE, 2021, 第 7 作者
(6) Genistein inhibits radiation-induced invasion and migration of glioblastoma cells by blocking the DNA-PKcs/Akt2/Rac1 signaling pathway, RADIOTHERAPY AND ONCOLOGY, 2021, 第 8 作者
(7) Citrulline, A Potential Biomarker of Radiation-Induced SmallIntestine Damage, DOSE-RESPONSE, 2020, 第 1 作者
(8) Inhibition of endoplasmic reticulum stress-induced autophagy promotes the killing effect of X-rays on sarcoma in mice, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 第 6 作者
(9) Different mitochondrial fragmentation after irradiation with X-rays and carbon ions in HeLa cells and its influence on cellular apoptosis, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 第 6 作者
(10) Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways, RADIOTHERAPY AND ONCOLOGY, 2018, 第 9 作者
(11) Inhibiting autophagy with chloroquine enhances the anti-tumor effect of high-LET carbon ions via ER stress-related apoptosis, MEDICAL ONCOLOGY, 2017, 第 6 作者
(12) The influence of non-DNA-targeted effects on carbon ion-induced low-dose hyper-radiosensitivity in MRC-5 cells, JOURNAL OF RADIATION RESEARCH, 2016, 第 1 作者
(13) The synergistic radiosensitizing effect of tirapazamine-conjugated gold nanoparticles on human hepatoma HepG2 cells under X-ray irradiation, INTERNATIONAL JOURNAL OF NANOMEDICINE, 2016, 第 6 作者
(14) Radiosensitizing effect of functionalized gold nanoparticles on human hepatoma HepG2 cells, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2016, 第 5 作者
(15) The Radiation Enhancement of 15 nm Citrate-Capped Gold Nanoparticles Exposed to 70 keV/mu m Carbon Ions, JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2016, 第 6 作者
(16) Different Roles of CHOP and JNK in Mediating Radiation-Induced Autophagy and Apoptosis in Breast Cancer Cells, RADIATION RESEARCH, 2016, 第 6 作者
(17) 碳离子辐照发育中小鼠对海马体中NRF2和自噬通路的长期影响, Sci Rep, 2015, 第 1 作者
(18) The dependence of radiation enhancement effect on the concentration of gold nanoparticles exposed to low- and high-LET radiations, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 2015, 第 7 作者
(19) Long-term Autophagy and Nrf2 Signaling in the Hippocampi of Developing Mice after Carbon Ion Exposure, SCIENTIFIC REPORTS, 2015, 第 1 作者
(20) The dependence of radiation enhancement effect on the concentration of gold nanoparticles exposed to low- and high-LET radiations, PHYSICA MEDICA, 2015, 第 7 作者
(21) The first interdisciplinary experiments at the IMP high energy microbeam, NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, 2015, 第 6 作者
(22) 非靶效应在碳离子引起的MRC-5细胞低剂量超敏感性中的影响, J Radiat Res, 2015, 第 1 作者
(23) The first interdisciplinary experiments at the IMP high energy microbeam, NUCLEAR INST. AND METHODS IN PHYSICS RESEARCH, B, 2015, 第 6 作者
(24) 自噬在高传能线密度辐射诱导的肿瘤细胞毒性中的作用, Cancer Sci, 2014, 第 1 作者
(25) Mitotic DNA damages induced by carbon-ion radiation incur additional chromosomal breaks in polyploidy, Toxicology Letters, 2014, 第 6 作者
(26) Role of autophagy in high linear energy transfer radiation-induced cytotoxicity to tumor cells, CANCER SCIENCE, 2014, 第 3 作者
(27) 辐照诱导人正常肝细胞系HL-7702细胞远后的微卫星不稳定性, Radiation-induced Delayed Microsatellite Instability in Human Normal Liver HL-7702 Cells, 原子核物理评论, 2013, 第 2 作者
(28) Genistein Enhances the Radiosensitivity of Breast Cancer Cells via G(2)/M Cell Cycle Arrest and Apoptosis, MOLECULES, 2013, 第 5 作者
(29) Genistein Enhances the Radiosensitivity of Breast Cancer Cells via G2/M Cell Cycle Arrest and Apoptosis, MOLECULES, 2013, 第 5 作者
(30) Experimental measurement of the correlation between CT number and heavy ion range, CHINESE PHYSICS C, 2012, 第 4 作者
(31) Experimental measurement of the correlation between CT number and heavy ion range, CHINESE PHYSICS C, 2012, 第 4 作者
(32) 面向HIRFL-CSR主动式点扫描技术的剂量标定方法研究, Calibration Procedure for Beam Monitors in Scanned Carbon Beam Therapy at HIRFL, NUCLEAR PHYSICS REVIEW, 2012, 第 4 作者
(33) 面向HIRFL-CSR主动式点扫描技术的剂量标定方法研究(英文), 原子核物理评论, 2012, 第 4 作者
(34) 重离子治癌相关研究, Researches Related to Heavy Ion Cancer Therapy, 原子核物理评论, 2010, 第 1 作者
(35) 重离子治癌相关研究;Researches Related to Heavy Ion Cancer Therapy, 原子核物理评论, 2010, 第 1 作者
(36) 初步的IMP重离子治疗计划系统;A Preliminary Version of Heavy Ion Treatment Planning System at IMP, 原子核物理评论, 2010, 第 6 作者
(37) 初步的IMP重离子治疗计划系统, A Preliminary Version of Heavy Ion Treatment Planning System at IMP, 原子核物理评论, 2010, 第 6 作者
(38) 自制CsI(Tl)晶体的光输出非均匀性, 原子能科学技术, 2008, 第 9 作者
(39) Property measurement of the CsI(Tl) crystal prepared at IMP, Property measurement of the CsI(Tl) crystal prepared at IMP, CHINESE PHYSICS C, 2008,
(40) Property measurement of the CsI(Tl) crystal prepared at IMP, Property measurement of the CsI(Tl) crystal prepared at IMP, 中国物理C:英文版, 2008, 第 13 作者
(41) 自制CsI(TI)晶体的光输出非均匀性, Non-uniformity of Home-Made CsI(Tl) Crystal, 原子能科学技术, 2008, 第 9 作者
(2) Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy, EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 第 3 作者
(3) Mitochondrial-Targeted Antioxidant MitoQ-Mediated Autophagy: A Novel Strategy for Precise Radiation Protection, ANTIOXIDANTS, 2023, 第 4 作者
(4) PERK Regulates the Sensitivity of Hepatocellular Carcinoma Cells to High-LET Carbon Ions via either Apoptosis or Ferroptosis, JOURNAL OF CANCER, 2022, 第 6 作者
(5) Hyperthermia ablation combined with transarterial chemoembolization versus monotherapy for hepatocellular carcinoma: A systematic review and meta-analysis, CANCER MEDICINE, 2021, 第 7 作者
(6) Genistein inhibits radiation-induced invasion and migration of glioblastoma cells by blocking the DNA-PKcs/Akt2/Rac1 signaling pathway, RADIOTHERAPY AND ONCOLOGY, 2021, 第 8 作者
(7) Citrulline, A Potential Biomarker of Radiation-Induced SmallIntestine Damage, DOSE-RESPONSE, 2020, 第 1 作者
(8) Inhibition of endoplasmic reticulum stress-induced autophagy promotes the killing effect of X-rays on sarcoma in mice, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 第 6 作者
(9) Different mitochondrial fragmentation after irradiation with X-rays and carbon ions in HeLa cells and its influence on cellular apoptosis, BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 第 6 作者
(10) Genistein sensitizes glioblastoma cells to carbon ions via inhibiting DNA-PKcs phosphorylation and subsequently repressing NHEJ and delaying HR repair pathways, RADIOTHERAPY AND ONCOLOGY, 2018, 第 9 作者
(11) Inhibiting autophagy with chloroquine enhances the anti-tumor effect of high-LET carbon ions via ER stress-related apoptosis, MEDICAL ONCOLOGY, 2017, 第 6 作者
(12) The influence of non-DNA-targeted effects on carbon ion-induced low-dose hyper-radiosensitivity in MRC-5 cells, JOURNAL OF RADIATION RESEARCH, 2016, 第 1 作者
(13) The synergistic radiosensitizing effect of tirapazamine-conjugated gold nanoparticles on human hepatoma HepG2 cells under X-ray irradiation, INTERNATIONAL JOURNAL OF NANOMEDICINE, 2016, 第 6 作者
(14) Radiosensitizing effect of functionalized gold nanoparticles on human hepatoma HepG2 cells, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2016, 第 5 作者
(15) The Radiation Enhancement of 15 nm Citrate-Capped Gold Nanoparticles Exposed to 70 keV/mu m Carbon Ions, JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2016, 第 6 作者
(16) Different Roles of CHOP and JNK in Mediating Radiation-Induced Autophagy and Apoptosis in Breast Cancer Cells, RADIATION RESEARCH, 2016, 第 6 作者
(17) 碳离子辐照发育中小鼠对海马体中NRF2和自噬通路的长期影响, Sci Rep, 2015, 第 1 作者
(18) The dependence of radiation enhancement effect on the concentration of gold nanoparticles exposed to low- and high-LET radiations, PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 2015, 第 7 作者
(19) Long-term Autophagy and Nrf2 Signaling in the Hippocampi of Developing Mice after Carbon Ion Exposure, SCIENTIFIC REPORTS, 2015, 第 1 作者
(20) The dependence of radiation enhancement effect on the concentration of gold nanoparticles exposed to low- and high-LET radiations, PHYSICA MEDICA, 2015, 第 7 作者
(21) The first interdisciplinary experiments at the IMP high energy microbeam, NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS, 2015, 第 6 作者
(22) 非靶效应在碳离子引起的MRC-5细胞低剂量超敏感性中的影响, J Radiat Res, 2015, 第 1 作者
(23) The first interdisciplinary experiments at the IMP high energy microbeam, NUCLEAR INST. AND METHODS IN PHYSICS RESEARCH, B, 2015, 第 6 作者
(24) 自噬在高传能线密度辐射诱导的肿瘤细胞毒性中的作用, Cancer Sci, 2014, 第 1 作者
(25) Mitotic DNA damages induced by carbon-ion radiation incur additional chromosomal breaks in polyploidy, Toxicology Letters, 2014, 第 6 作者
(26) Role of autophagy in high linear energy transfer radiation-induced cytotoxicity to tumor cells, CANCER SCIENCE, 2014, 第 3 作者
(27) 辐照诱导人正常肝细胞系HL-7702细胞远后的微卫星不稳定性, Radiation-induced Delayed Microsatellite Instability in Human Normal Liver HL-7702 Cells, 原子核物理评论, 2013, 第 2 作者
(28) Genistein Enhances the Radiosensitivity of Breast Cancer Cells via G(2)/M Cell Cycle Arrest and Apoptosis, MOLECULES, 2013, 第 5 作者
(29) Genistein Enhances the Radiosensitivity of Breast Cancer Cells via G2/M Cell Cycle Arrest and Apoptosis, MOLECULES, 2013, 第 5 作者
(30) Experimental measurement of the correlation between CT number and heavy ion range, CHINESE PHYSICS C, 2012, 第 4 作者
(31) Experimental measurement of the correlation between CT number and heavy ion range, CHINESE PHYSICS C, 2012, 第 4 作者
(32) 面向HIRFL-CSR主动式点扫描技术的剂量标定方法研究, Calibration Procedure for Beam Monitors in Scanned Carbon Beam Therapy at HIRFL, NUCLEAR PHYSICS REVIEW, 2012, 第 4 作者
(33) 面向HIRFL-CSR主动式点扫描技术的剂量标定方法研究(英文), 原子核物理评论, 2012, 第 4 作者
(34) 重离子治癌相关研究, Researches Related to Heavy Ion Cancer Therapy, 原子核物理评论, 2010, 第 1 作者
(35) 重离子治癌相关研究;Researches Related to Heavy Ion Cancer Therapy, 原子核物理评论, 2010, 第 1 作者
(36) 初步的IMP重离子治疗计划系统;A Preliminary Version of Heavy Ion Treatment Planning System at IMP, 原子核物理评论, 2010, 第 6 作者
(37) 初步的IMP重离子治疗计划系统, A Preliminary Version of Heavy Ion Treatment Planning System at IMP, 原子核物理评论, 2010, 第 6 作者
(38) 自制CsI(Tl)晶体的光输出非均匀性, 原子能科学技术, 2008, 第 9 作者
(39) Property measurement of the CsI(Tl) crystal prepared at IMP, Property measurement of the CsI(Tl) crystal prepared at IMP, CHINESE PHYSICS C, 2008,
(40) Property measurement of the CsI(Tl) crystal prepared at IMP, Property measurement of the CsI(Tl) crystal prepared at IMP, 中国物理C:英文版, 2008, 第 13 作者
(41) 自制CsI(TI)晶体的光输出非均匀性, Non-uniformity of Home-Made CsI(Tl) Crystal, 原子能科学技术, 2008, 第 9 作者