General

Ph.D. & Associate Professor Hongyan Li

Institute of Modern Physics, Chinese Academy of Sciences

E-mail: lihy@impcas.ac.cn

Address: 509 Nanchang Rd., Lanzhou 730000, China

Postcode: 730000


Research Areas

Heavy Ion Radiation Biology and Medicine 

Radiation Toxicology

Cell Biology

Education

2013-2014, MPG (Max Planck Institute in Germany) and CAS (Chinese Academy of Sciences) joint Ph.D.

2011-2014, Ph.D. in Institute of Modern Physics, CAS, Lanzhou, China.

2008-2011, M.S. in Gansu Agricultural University, Lanzhou, China.

2004-2008, B.S. in Gansu Agricultural University, Lanzhou, China. 


Experience



Work Experience

Since Nov 2016, Associate professor in Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China.  

Oct 2014-Oct 2016, Research assistant in Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, China. 



Publications

   
Papers

(1) Mitochondrial proteomics reveals the mechanism of spermatogenic cells apoptosis induced by carbon ion radiation in zebrafish, Journal of cellular physiology, 2019first author

(2) Apoptosis Induction by Iron Radiation via Inhibition of Autophagy in Trp53 +/- Mouse Testes: Is Chronic Restraint - Induced Stress a Modifying Factor?, International Journal of Biological Sciences, 2018, first author

(3) Comparative proteomics reveals the underlying toxicological mechanism of low sperm motility induced by iron ion radiation in mice, Reproductive Toxicology, 2016, first author

(4) Comparative analysis of the serum proteome for biomarker discovery to reveal hepatotoxicity induced by iron ion radiation in mice, Life Sciences, 2016, first author
(5) Comparative proteomic profiling and possible toxicological mechanism of acute injury induced by carbon ion radiation in pubertal mice testes, Reproductive Toxicology, 2015, first author
(6) Differential proteome and gene expression reveal response to carbon ion irradiation in pubertal mice testes, Toxicology Letters, 2014, first author
(7) Carbon Ion Irradiation Induces Reduction of b-tubulin in Sperm of Pubertal Mice, Biomedical and Environmental Sciences, 2014, first author
(8) Proteome analysis for profiling infertility markers in male mouse sperm after carbon ion radiation, Toxicology, 2013, first author
(9) Proteomic analysis for testis of mice exposed to carbon ion radiation, Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 2013, first author
(10) Simulated microgravity conditions and carbon ion irradiation induce spermatogenic cell apoptosis and sperm DNA damage, Biomedical and Environmental Sciences, 2013, first author


Research Interests

I pay more attention to the heavy-ion biology research. On the one hand, I continue to focus on the effects of radiotherapy on male reproductive system by using mice model, because radiation impairs spermatogenesis and leads to infertility. On the other hand, combined with the research focus of our laboratory, I am gradually doing the mechanism study of heavy-ion radiotherapy and I choose the research subject is “The mechanism of radiation-induced cellular apoptosis without p53”. 


Students

现指导学生

徐度玲  硕士研究生  071011-生物物理学  

Honors & Distinctions

Second Class Prize of Gansu Medical Science and Technology Award, 2018

First Class Prize of Gansu Environmental Science and Technology Award, 2018

Second Class Prize of Gansu Province Science and Technology Progress Award, 2016

Chinese Academy of Sciences President Award, 2014

Second Class Prize of Gansu Province Science and Technology Progress Award, 2014